Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 52728981 | . | G | A | CCDS12849.1:NM_014225.5:c.1673aGt>aAt_NP_055040.2:p.558S>N | Homo sapiens protein phosphatase 2 scaffold subunit Aalpha (PPP2R1A), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 2ie3 | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-11-07 | SER | A:558 | A:558 | 63.0 | 0.548 | I | -65.6 | -57.0 | 63.0 | 0.548 | 0.0 | ||||||
| 2ie4 | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-11-07 | SER | A:558 | A:558 | 76.0 | 0.661 | I | -88.2 | -23.5 | 76.0 | 0.661 | 0.0 | ||||||
| 2npp | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | SER | A:558 | A:558 | 75.0 | 0.652 | I | -176.5 | -41.6 | NA | NA | NA | ||||||
| SER | D:558 | D:558 | 77.0 | 0.67 | I | -174.7 | -39.7 | 77.0 | 0.67 | 0.0 | |||||||||||||
| 3k7v | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2009-11-03 | SER | A:558 | A:558 | 70.0 | 0.609 | I | -81.1 | -38.8 | 70.0 | 0.609 | 0.0 | ||||||
| 3k7w | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2009-11-03 | SER | A:558 | A:558 | 71.0 | 0.617 | I | -80.8 | -46.0 | 71.0 | 0.617 | 0.0 | ||||||
| 6nts | 1 | P30153 | 100.0 | 0.0 |
EM |
2020-05-06 | SER | A:558 | A:558 | 76.0 | 0.661 | I | -75.8 | -46.7 | 76.0 | 0.661 | 0.0 | ||||||
| 7cun | 10 | P30153 | 100.0 | 0.0 |
EM |
2020-11-25 | SER | J:558 | P:558 | 65.0 | 0.565 | I | -76.8 | -60.4 | 65.0 | 0.565 | 0.0 | ||||||
| 7k36 | 1 | P30153 | 100.0 | 0.0 |
EM |
2021-03-10 | SER | A:558 | A:558 | 57.0 | 0.496 | I | -80.9 | -47.6 | 57.0 | 0.496 | 0.0 | ||||||
| 7pks | 31 | P30153 | 100.0 | 0.0 |
EM |
2021-12-08 | SER | EA:558 | p:558 | 85.0 | 0.739 | I | -70.6 | -42.7 | 85.0 | 0.739 | 0.0 | ||||||
| 2iae | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2006-12-26 | SER | A:558 | A:558 | 78.0 | 0.678 | S | -132.0 | -7.5 | 78.0 | 0.678 | 0.0 | ||||||
| SER | D:558 | D:558 | 67.0 | 0.583 | I | -105.1 | -44.8 | NA | NA | NA | |||||||||||||
| 2pf4 | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2007-08-07 | SER | A:558 | A:558 | 63.0 | 0.548 | I | -80.9 | -53.9 | 63.0 | 0.548 | 0.0 | ||||||
| SER | B:558 | B:558 | 69.0 | 0.6 | I | -78.3 | -46.2 | NA | NA | NA | |||||||||||||
| SER | C:558 | C:558 | 85.0 | 0.739 | I | -127.7 | -17.1 | NA | NA | NA | |||||||||||||
| SER | D:558 | D:558 | 76.0 | 0.661 | H | -100.2 | -9.4 | NA | NA | NA | |||||||||||||
| 1b3u | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
1999-04-12 | SER | A:557 | A:557 | 78.0 | 0.678 | I | -90.4 | -17.8 | 78.0 | 0.678 | 0.0 |
HOH |
2.806 |
OG |
O |
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| SER | B:557 | B:557 | 67.0 | 0.583 | I | -79.1 | -30.4 | NA | NA | NA | |||||||||||||
| 3fga | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2009-09-22 | SER | A:557 | A:558 | 83.0 | 0.722 | I | -93.7 | -21.8 | 83.0 | 0.722 | 0.0 |
HOH |
8.845 |
OG |
O |
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| 6ef4 | 1 | Q76MZ3 | 99.66 | 0.0 |
X-RAY |
2019-06-26 | SER | A:559 | A:558 | 73.0 | 0.635 | I | -67.9 | -71.0 | 73.0 | 0.635 | 0.0 | ||||||
| 6iur | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2019-12-04 | SER | A:556 | A:558 | 71.0 | 0.617 | I | -89.2 | -34.9 | 71.0 | 0.617 | 0.0 | ||||||
| SER | B:556 | B:558 | 80.0 | 0.696 | H | -52.9 | -13.6 | 80.0 | 0.696 | 0.0 | |||||||||||||
| SER | E:556 | E:558 | 61.0 | 0.53 | H | -78.9 | -32.1 | NA | NA | NA | |||||||||||||
| SER | F:556 | F:558 | 73.0 | 0.635 | I | -86.2 | -37.9 | NA | NA | NA | |||||||||||||
| 2nyl | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | SER | A:551 | A:558 | 66.0 | 0.574 | I | -90.8 | -77.6 | 66.0 | 0.574 | 0.0 | ||||||
| SER | D:551 | D:558 | 70.0 | 0.609 | I | -98.5 | -74.1 | NA | NA | NA | |||||||||||||
| 2nym | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | SER | A:551 | A:558 | 64.0 | 0.557 | I | -132.3 | -63.8 | 64.0 | 0.557 | 0.0 | ||||||
| SER | D:551 | D:558 | 69.0 | 0.6 | I | -133.3 | -58.5 | NA | NA | NA | |||||||||||||
| 4i5l | 1 | P30153 | 99.66 | 0.0 |
X-RAY |
2013-05-08 | SER | A:553 | A:558 | 82.0 | 0.713 | I | -90.3 | -26.2 | 82.0 | 0.713 | 0.0 |
HOH |
5.695 |
N |
O |
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| SER | D:553 | D:558 | 85.0 | 0.739 | I | -86.2 | -30.0 | NA | NA | NA | |||||||||||||
| 4i5n | 1 | P30153 | 99.66 | 0.0 |
X-RAY |
2013-05-08 | SER | A:553 | A:558 | 78.0 | 0.678 | I | -84.8 | -45.6 | 78.0 | 0.678 | 0.0 |
HOH |
7.929 |
OG |
O |
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| SER | D:553 | D:558 | 81.0 | 0.704 | I | -98.5 | -26.8 | NA | NA | NA | |||||||||||||
| 3dw8 | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2008-10-07 | SER | A:551 | A:558 | 62.0 | 0.539 | H | -43.7 | -88.3 | 62.0 | 0.539 | 0.0 | ||||||
| SER | D:551 | D:558 | 48.0 | 0.417 | H | -42.0 | -93.0 | NA | NA | NA | |||||||||||||
| 5w0w | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2018-01-17 | SER | A:554 | A:558 | 66.0 | 0.574 | I | -92.3 | -61.6 | 66.0 | 0.574 | 0.0 | ||||||
| SER | D:554 | D:558 | 73.0 | 0.635 | I | -94.3 | -61.2 | NA | NA | NA | |||||||||||||
| SER | G:554 | G:558 | 82.0 | 0.713 | I | -96.0 | -58.4 | NA | NA | NA | |||||||||||||
| SER | J:554 | J:558 | 75.0 | 0.652 | I | -129.1 | -33.1 | NA | NA | NA | |||||||||||||
| 2pkg | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2007-05-15 | SER | A:549 | A:558 | 85.0 | 0.739 | I | -80.9 | -49.3 | 85.0 | 0.739 | 0.0 | ||||||
| SER | B:549 | B:558 | 79.0 | 0.687 | I | -79.3 | -55.6 | NA | NA | NA | |||||||||||||
| 3c5w | 1 | P30153 | 88.39 | 1e-141 |
X-RAY |
2008-04-15 | SER | A:201 | A:558 | 80.0 | 0.696 | I | -101.8 | -22.7 | 80.0 | 0.696 | 0.0 | ||||||
| 4lac | 2 | ? | 85.71 | 9e-137 |
X-RAY |
2013-10-09 | SER | B:227 | A:558 | 72.0 | 0.626 | I | -99.6 | -34.8 | 72.0 | 0.626 | 0.0 | ||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p30153-f1 | 1 | P30153 | 100.0 | 0.0 | SER | A:558 | A:558 | 78.0 | 0.678 | I | -85.2 | -31.3 | |
| af-p30154-f1 | 1 | P30154 | 86.4 | 0.0 | GLY | A:570 | A:570 | 54.0 | 0.72 | I | -85.0 | -31.7 | |