Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 52729031 | . | G | A | CCDS12849.1:NM_014225.5:c.1723Gtc>Atc_NP_055040.2:p.575V>I | Homo sapiens protein phosphatase 2 scaffold subunit Aalpha (PPP2R1A), transcript variant 1, mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 2ie3 | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-11-07 | VAL | A:575 | A:575 | 0.0 | 0.0 | H | -62.9 | -43.8 | 0.0 | 0.0 | 0.0 | ||||||
| 2ie4 | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-11-07 | VAL | A:575 | A:575 | 0.0 | 0.0 | H | -68.6 | -38.5 | 0.0 | 0.0 | 0.0 |
HOH |
6.932 |
CG2 |
O |
||
| 2npp | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | VAL | A:575 | A:575 | 0.0 | 0.0 | H | -55.3 | -37.9 | NA | NA | NA | ||||||
| VAL | D:575 | D:575 | 0.0 | 0.0 | H | -51.6 | -40.2 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 3k7v | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2009-11-03 | VAL | A:575 | A:575 | 0.0 | 0.0 | H | -65.3 | -42.3 | 0.0 | 0.0 | 0.0 |
SO4 HOH |
6.290 7.525 |
CG2 N |
O3 O |
||
| 3k7w | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2009-11-03 | VAL | A:575 | A:575 | 0.0 | 0.0 | H | -64.7 | -38.7 | 0.0 | 0.0 | 0.0 |
SO4 HOH |
6.240 7.834 |
CG2 CG2 |
O3 O |
||
| 6nts | 1 | P30153 | 100.0 | 0.0 |
EM |
2020-05-06 | VAL | A:575 | A:575 | 0.0 | 0.0 | H | -62.2 | -35.4 | 0.0 | 0.0 | 0.0 | ||||||
| 7cun | 10 | P30153 | 100.0 | 0.0 |
EM |
2020-11-25 | VAL | J:575 | P:575 | 0.0 | 0.0 | H | -64.2 | -35.3 | 0.0 | 0.0 | 0.0 | ||||||
| 7k36 | 1 | P30153 | 100.0 | 0.0 |
EM |
2021-03-10 | VAL | A:575 | A:575 | 0.0 | 0.0 | H | -67.0 | -34.5 | 0.0 | 0.0 | 0.0 | ||||||
| 7pks | 31 | P30153 | 100.0 | 0.0 |
EM |
2021-12-08 | VAL | EA:575 | p:575 | 0.0 | 0.0 | H | -63.1 | -43.2 | 0.0 | 0.0 | 0.0 | ||||||
| 2iae | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2006-12-26 | VAL | A:575 | A:575 | 4.0 | 0.026 | H | -67.0 | -38.1 | 4.0 | 0.026 | 0.0 | ||||||
| VAL | D:575 | D:575 | 5.0 | 0.032 | H | -45.8 | -37.3 | NA | NA | NA | |||||||||||||
| 2pf4 | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2007-08-07 | VAL | A:575 | A:575 | 0.0 | 0.0 | H | -66.4 | -45.1 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | B:575 | B:575 | 1.0 | 0.006 | H | -52.9 | -60.9 | NA | NA | NA | |||||||||||||
| VAL | C:575 | C:575 | 0.0 | 0.0 | H | -66.9 | -54.5 | NA | NA | NA | |||||||||||||
| VAL | D:575 | D:575 | 16.0 | 0.103 | S | -131.3 | -22.1 | NA | NA | NA | |||||||||||||
| 1b3u | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
1999-04-12 | VAL | A:574 | A:574 | 0.0 | 0.0 | H | -61.0 | -45.7 | 0.0 | 0.0 | 0.0 |
HOH |
6.266 |
N |
O |
||
| VAL | B:574 | B:574 | 0.0 | 0.0 | T | -76.4 | 14.4 | NA | NA | NA | |||||||||||||
| 3fga | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2009-09-22 | VAL | A:574 | A:575 | 0.0 | 0.0 | H | -67.5 | -47.3 | 0.0 | 0.0 | 0.0 | ||||||
| 6ef4 | 1 | Q76MZ3 | 99.66 | 0.0 |
X-RAY |
2019-06-26 | VAL | A:576 | A:575 | 0.0 | 0.0 | H | -68.3 | -54.1 | 0.0 | 0.0 | 0.0 | ||||||
| 6iur | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2019-12-04 | VAL | A:573 | A:575 | 0.0 | 0.0 | H | -61.6 | -40.4 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | B:573 | B:575 | 21.0 | 0.135 | H | -50.5 | -48.3 | 21.0 | 0.135 | 0.0 | |||||||||||||
| VAL | E:573 | E:575 | 0.0 | 0.0 | H | -56.7 | -50.2 | NA | NA | NA | |||||||||||||
| VAL | F:573 | F:575 | 0.0 | 0.0 | H | -60.1 | -40.8 | NA | NA | NA | |||||||||||||
| 2nyl | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | VAL | A:568 | A:575 | 0.0 | 0.0 | H | -50.6 | -54.0 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | D:568 | D:575 | 0.0 | 0.0 | H | -49.5 | -45.0 | NA | NA | NA | |||||||||||||
| 2nym | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | VAL | A:568 | A:575 | 0.0 | 0.0 | H | -43.4 | -44.4 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | D:568 | D:575 | 0.0 | 0.0 | H | -45.9 | -38.0 | NA | NA | NA | |||||||||||||
| 4i5l | 1 | P30153 | 99.66 | 0.0 |
X-RAY |
2013-05-08 | VAL | A:570 | A:575 | 0.0 | 0.0 | H | -68.8 | -36.7 | 0.0 | 0.0 | 0.0 |
HOH |
5.285 |
CG2 |
O |
||
| VAL | D:570 | D:575 | 0.0 | 0.0 | H | -58.5 | -54.6 | NA | NA | NA | |||||||||||||
| 4i5n | 1 | P30153 | 99.66 | 0.0 |
X-RAY |
2013-05-08 | VAL | A:570 | A:575 | 0.0 | 0.0 | H | -69.5 | -38.8 | 0.0 | 0.0 | 0.0 |
HOH |
5.354 |
CG2 |
O |
||
| VAL | D:570 | D:575 | 0.0 | 0.0 | H | -69.9 | -41.5 | NA | NA | NA | |||||||||||||
| 3dw8 | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2008-10-07 | VAL | A:568 | A:575 | 0.0 | 0.0 | H | -87.3 | -27.9 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | D:568 | D:575 | 0.0 | 0.0 | H | -99.5 | -29.3 | NA | NA | NA | |||||||||||||
| 5w0w | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2018-01-17 | VAL | A:571 | A:575 | 1.0 | 0.006 | H | -59.9 | -39.3 | 1.0 | 0.006 | 0.0 | ||||||
| VAL | D:571 | D:575 | 1.0 | 0.006 | H | -66.0 | -44.4 | NA | NA | NA | |||||||||||||
| VAL | G:571 | G:575 | 0.0 | 0.0 | H | -68.5 | -42.9 | NA | NA | NA | |||||||||||||
| VAL | J:571 | J:575 | 0.0 | 0.0 | H | -56.9 | -32.5 | NA | NA | NA | |||||||||||||
| 2pkg | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2007-05-15 | VAL | A:566 | A:575 | 0.0 | 0.0 | H | -50.6 | -55.4 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | B:566 | B:575 | 0.0 | 0.0 | H | -61.1 | -62.0 | NA | NA | NA | |||||||||||||
| 3c5w | 1 | P30153 | 88.39 | 1e-141 |
X-RAY |
2008-04-15 | VAL | A:218 | A:575 | 0.0 | 0.0 | H | -52.0 | -45.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.772 |
CG2 |
O |
||
| 4lac | 2 | ? | 85.71 | 9e-137 |
X-RAY |
2013-10-09 | VAL | B:244 | A:575 | 0.0 | 0.0 | H | -62.3 | -49.7 | 0.0 | 0.0 | 0.0 |
HOH |
5.709 |
CG1 |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p30153-f1 | 1 | P30153 | 100.0 | 0.0 | VAL | A:575 | A:575 | 0.0 | 0.0 | H | -58.7 | -46.5 | |
| af-p30154-f1 | 1 | P30154 | 86.4 | 0.0 | VAL | A:587 | A:587 | 0.0 | 0.0 | H | -59.2 | -46.4 | |