Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6678452 . G A CCDS32883.1:NM_000064.2:c.4645Ctg>Ttg_NP_000055.2:p.1549L>L Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 LEU B:878 B:1549 0.0 0.0 E -68.1 100.8 0.0 0.0 0.0
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 LEU B:877 B:1527 0.0 0.0 E -66.0 109.2 0.0 0.0 0.0
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 LEU B:801 B:1527 1.0 0.006 E -80.0 116.0 1.0 0.006 0.0
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 LEU B:801 B:1527 0.0 0.0 E -72.2 103.1 0.0 0.0 0.0 GOL
HOH
 9.229
7.307
 N
CD2
 O1
O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 LEU B:801 B:1527 0.0 0.0 E -65.9 119.3 0.0 0.0 0.0
LEU D:801 D:1527 0.0 0.0 E -66.1 119.3 NA NA NA
LEU F:801 F:1527 0.0 0.0 E -66.1 119.3 NA NA NA
LEU H:801 H:1527 0.0 0.0 E -66.0 119.3 0.0 0.0 0.0
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 LEU B:801 B:1527 0.0 0.0 E -76.0 101.7 0.0 0.0 0.0
LEU D:801 D:1527 0.0 0.0 E -68.3 107.6 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 LEU B:801 B:1527 0.0 0.0 E -61.9 123.0 0.0 0.0 0.0
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 LEU B:801 B:1549 0.0 0.0 E -73.0 102.5 0.0 0.0 0.0
LEU G:801 F:1549 0.0 0.0 E -72.3 102.7 0.0 0.0 0.0
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 LEU B:801 B:1549 0.0 0.0 E -73.2 103.6 0.0 0.0 0.0
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 LEU F:801 B:1527 0.0 0.0 E -75.6 128.5 0.0 0.0 0.0
LEU H:801 H:1527 0.0 0.0 E -74.6 128.6 0.0 0.0 0.0
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 LEU H:801 B:1527 0.0 0.0 E -77.0 138.5 0.0 0.0 0.0
LEU J:801 H:1527 0.0 0.0 E -77.2 138.7 0.0 0.0 0.0
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 LEU B:801 B:1527 0.0 0.0 E -81.3 104.7 0.0 0.0 0.0 PEG
HOH
 8.736
6.473
 CD2
CD2
 O2
O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 LEU B:801 B:1527 0.0 0.0 E -85.6 105.3 0.0 0.0 0.0
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 LEU B:801 B:1527 0.0 0.0 E -61.5 104.0 0.0 0.0 0.0
LEU D:801 D:1527 0.0 0.0 E -61.7 104.3 NA NA NA
LEU F:801 F:1527 0.0 0.0 E -61.7 104.3 NA NA NA
LEU H:801 H:1527 0.0 0.0 E -62.0 104.2 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 LEU B:801 B:1549 0.0 0.0 E -72.6 102.6 0.0 0.0 0.0
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 LEU B:801 B:1549 0.0 0.0 E -73.9 108.2 0.0 0.0 0.0 EDO
HOH
 9.705
5.350
 N
CD2
 C1
O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 LEU B:801 B:1549 1.0 0.006 E -77.4 118.0 NA NA NA
LEU E:801 E:1549 0.0 0.0 E -78.5 118.6 0.0 0.0 0.0
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 LEU B:801 B:1549 0.0 0.0 E -86.2 106.9 0.0 0.0 0.0
LEU D:801 D:1549 0.0 0.0 E -86.6 104.8 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 LEU B:801 B:1549 0.0 0.0 E -74.2 112.6 0.0 0.0 0.0 HOH
 3.774
 O
 O
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 LEU B:801 B:1549 0.0 0.0 E -72.2 117.3 0.0 0.0 0.0
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 LEU B:801 B:1549 0.0 0.0 E -72.3 117.3 0.0 0.0 0.0
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 LEU B:798 B:1527 0.0 0.0 E -67.0 98.2 0.0 0.0 0.0
LEU D:798 D:1527 0.0 0.0 E -67.4 98.2 NA NA NA
2a74 3 P01024 100.0 0.0 X-RAY
 2005-09-27 LEU C:229 C:1527 0.0 0.0 E -80.8 108.0 0.0 0.0 0.0 GOL
HOH
 8.435
8.651
 CD2
N
 O1
O
LEU F:229 F:1527 0.0 0.0 E -80.1 111.4 NA NA NA
2ice 3 P01024 100.0 0.0 X-RAY
 2006-11-07 LEU C:229 C:1527 1.0 0.006 E -87.2 117.3 1.0 0.006 0.0
LEU G:229 F:1527 0.0 0.0 E -63.1 138.5 NA NA NA
2qki 3 P01024 100.0 0.0 X-RAY
 2007-08-14 LEU C:229 C:1527 0.0 0.0 E -77.5 110.8 0.0 0.0 0.0 GOL
 7.388
 N
 O1
LEU F:229 F:1527 1.0 0.006 E -73.6 111.8 NA NA NA
3l3o 4 P01024 100.0 0.0 X-RAY
 2010-08-04 LEU E:229 F:1527 2.0 0.012 E -99.7 113.4 NA NA NA
LEU G:229 C:1527 1.0 0.006 E -99.7 113.3 1.0 0.006 0.0
3nms 2 P01024 100.0 0.0 X-RAY
 2010-08-04 LEU B:229 C:1527 0.0 0.0 E -93.5 115.5 0.0 0.0 0.0
3ohx 3 P01024 100.0 0.0 X-RAY
 2010-09-01 LEU C:229 C:1527 1.0 0.006 E -57.5 114.7 1.0 0.006 0.0
LEU G:229 F:1527 0.0 0.0 E -61.9 127.6 NA NA NA
3t4a 3 P01024 100.0 0.0 X-RAY
 2011-11-23 LEU C:229 C:1527 1.0 0.006 E -82.4 98.2 1.0 0.006 0.0
LEU F:229 F:1527 0.0 0.0 E -82.4 98.3 NA NA NA
6s0b 3 P01024 100.0 2e-99 X-RAY
 2019-09-04 LEU C:35 C:1549 0.0 0.0 E -73.9 97.1 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 LEU A:1549 A:1549 0.0 0.0 E -75.0 115.6