Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6682235 . C A CCDS32883.1:NM_000064.2:c.4178cGg>cTg_NP_000055.2:p.1393R>L Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 ARG B:722 B:1393 138.0 0.613 -98.4 7.3 138.0 0.613 0.0
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 ARG B:721 B:1371 116.0 0.516 -98.9 26.3 116.0 0.516 0.0
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 ARG B:645 B:1371 97.0 0.431 S -71.1 160.6 97.0 0.431 0.0
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 ARG B:645 B:1371 108.0 0.48 -91.8 88.5 108.0 0.48 0.0 HOH
 7.346
 O
 O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 ARG B:645 B:1371 129.0 0.573 -85.3 37.4 129.0 0.573 0.0
ARG D:645 D:1371 122.0 0.542 -85.4 37.4 NA NA NA
ARG F:645 F:1371 117.0 0.52 -85.1 39.3 NA NA NA
ARG H:645 H:1371 118.0 0.524 -85.2 39.3 118.0 0.524 0.0
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 ARG B:645 B:1371 107.0 0.476 S -122.5 111.6 107.0 0.476 0.0
ARG D:645 D:1371 102.0 0.453 S -60.4 139.3 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 ARG B:645 B:1371 122.0 0.542 -79.5 49.8 122.0 0.542 0.0
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 ARG B:645 B:1393 136.0 0.604 -92.5 67.9 136.0 0.604 0.0
ARG G:645 F:1393 127.0 0.564 -92.3 67.5 127.0 0.564 0.0
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 ARG B:645 B:1393 124.0 0.551 -91.6 67.9 124.0 0.551 0.0
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 ARG F:645 B:1371 123.0 0.547 -96.8 -9.1 123.0 0.547 0.0
ARG H:645 H:1371 118.0 0.524 -96.1 -7.6 118.0 0.524 0.0
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 ARG H:645 B:1371 130.0 0.578 -99.3 -7.0 130.0 0.578 0.0
ARG J:645 H:1371 122.0 0.542 -99.0 -7.4 122.0 0.542 0.0
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 ARG B:645 B:1371 130.0 0.578 -97.0 79.7 130.0 0.578 0.0 HOH
 3.258
 CA
 O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 ARG B:645 B:1371 112.0 0.498 -99.0 29.6 112.0 0.498 0.0
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 ARG B:645 B:1371 142.0 0.631 -88.3 91.7 142.0 0.631 0.0
ARG D:645 D:1371 142.0 0.631 -88.4 91.5 NA NA NA
ARG F:645 F:1371 142.0 0.631 -88.2 91.4 NA NA NA
ARG H:645 H:1371 142.0 0.631 -88.2 91.7 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ARG B:645 B:1393 123.0 0.547 -91.3 68.3 123.0 0.547 0.0
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ARG B:645 B:1393 114.0 0.507 -97.3 84.6 114.0 0.507 0.0 EDO
HOH
 8.197
6.843
 CD
NE
 O2
O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ARG B:645 B:1393 97.0 0.431 -92.5 110.0 NA NA NA
ARG E:645 E:1393 123.0 0.547 -92.4 110.5 123.0 0.547 0.0
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ARG B:645 B:1393 122.0 0.542 -98.9 32.0 122.0 0.542 0.0
ARG D:645 D:1393 121.0 0.538 -99.7 32.0 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ARG B:645 B:1393 120.0 0.533 -103.4 12.8 120.0 0.533 0.0 GOL
HOH
 3.399
6.924
 O
CD
 C1
O
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 ARG B:645 B:1393 97.0 0.431 -96.8 26.4 97.0 0.431 0.0
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 ARG B:645 B:1393 94.0 0.418 -96.8 26.4 94.0 0.418 0.0
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 ARG B:642 B:1371 137.0 0.609 -91.9 87.5 137.0 0.609 0.0
ARG D:642 D:1371 139.0 0.618 -92.2 87.8 NA NA NA
2a74 3 P01024 100.0 0.0 X-RAY
 2005-09-27 ARG C:73 C:1371 129.0 0.573 -91.1 72.7 129.0 0.573 0.0 HOH
 2.771
 NE
 O
ARG F:73 F:1371 138.0 0.613 S -90.9 82.3 NA NA NA
2ice 3 P01024 100.0 0.0 X-RAY
 2006-11-07 ARG C:73 C:1371 112.0 0.498 S -105.0 125.3 112.0 0.498 0.0
ARG G:73 F:1371 129.0 0.573 S -130.5 85.2 NA NA NA
2qki 3 P01024 100.0 0.0 X-RAY
 2007-08-14 ARG C:73 C:1371 106.0 0.471 -97.9 55.8 106.0 0.471 0.0 HOH
 5.784
 CD
 O
ARG F:73 F:1371 132.0 0.587 -90.7 37.6 NA NA NA
3l3o 4 P01024 100.0 0.0 X-RAY
 2010-08-04 ARG E:73 F:1371 139.0 0.618 -89.5 91.1 NA NA NA
ARG G:73 C:1371 143.0 0.636 -89.6 91.1 143.0 0.636 0.0
3nms 2 P01024 100.0 0.0 X-RAY
 2010-08-04 ARG B:73 C:1371 145.0 0.644 -81.1 80.2 145.0 0.644 0.0
3ohx 3 P01024 100.0 0.0 X-RAY
 2010-09-01 ARG C:73 C:1371 138.0 0.613 -89.6 91.1 138.0 0.613 0.0
ARG G:73 F:1371 141.0 0.627 -89.6 91.2 NA NA NA
3t4a 3 P01024 100.0 0.0 X-RAY
 2011-11-23 ARG C:73 C:1371 140.0 0.622 -84.0 63.2 140.0 0.622 0.0
ARG F:73 F:1371 140.0 0.622 S -79.3 46.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 ARG A:1393 A:1393 134.0 0.596 -124.2 32.4