Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6684591 . A C CCDS32883.1:NM_000064.2:c.4100aTa>aGa_NP_000055.2:p.1367I>R Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 ILE B:696 B:1367 20.0 0.114 E -128.0 127.1 20.0 0.114 0.0
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 ILE B:695 B:1345 12.0 0.069 E -134.3 123.8 12.0 0.069 0.0
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 ILE B:619 B:1345 8.0 0.046 E -141.6 121.4 8.0 0.046 0.0
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 ILE B:619 B:1345 12.0 0.069 E -126.7 125.0 12.0 0.069 0.0 HOH
 9.725
 CD1
 O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 ILE B:619 B:1345 29.0 0.166 E -127.9 115.0 29.0 0.166 0.0
ILE D:619 D:1345 29.0 0.166 E -127.9 115.0 NA NA NA
ILE F:619 F:1345 29.0 0.166 E -128.0 114.2 NA NA NA
ILE H:619 H:1345 30.0 0.171 E -127.9 114.2 30.0 0.171 0.0
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 ILE B:619 B:1345 7.0 0.04 E -128.5 125.4 7.0 0.04 0.0
ILE D:619 D:1345 18.0 0.103 E -130.6 119.9 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 ILE B:619 B:1345 35.0 0.2 E -138.5 115.2 35.0 0.2 0.0
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 ILE B:619 B:1367 25.0 0.143 E -129.3 116.9 25.0 0.143 0.0
ILE G:619 F:1367 8.0 0.046 E -129.0 117.5 8.0 0.046 0.0
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 ILE B:619 B:1367 24.0 0.137 E -128.7 117.0 24.0 0.137 0.0
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 ILE F:619 B:1345 22.0 0.126 E -115.9 131.9 22.0 0.126 0.0
ILE H:619 H:1345 24.0 0.137 E -114.0 132.9 24.0 0.137 0.0
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 ILE H:619 B:1345 26.0 0.149 E -115.3 129.6 26.0 0.149 0.0
ILE J:619 H:1345 26.0 0.149 E -114.7 128.2 26.0 0.149 0.0
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 ILE B:619 B:1345 29.0 0.166 E -135.3 134.5 29.0 0.166 0.0 HOH
 2.737
 N
 O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 ILE B:619 B:1345 29.0 0.166 E -126.9 105.9 29.0 0.166 0.0
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 ILE B:619 B:1345 23.0 0.131 E -117.4 133.8 23.0 0.131 0.0
ILE D:619 D:1345 24.0 0.137 E -117.3 133.7 NA NA NA
ILE F:619 F:1345 25.0 0.143 E -117.2 133.9 NA NA NA
ILE H:619 H:1345 24.0 0.137 E -117.3 134.1 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ILE B:619 B:1367 25.0 0.143 E -128.9 116.8 25.0 0.143 0.0
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ILE B:619 B:1367 24.0 0.137 E -141.1 117.7 24.0 0.137 0.0 HOH
 5.200
 CD1
 O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ILE B:619 B:1367 12.0 0.069 E -112.2 115.4 NA NA NA
ILE E:619 E:1367 23.0 0.131 E -109.6 118.5 23.0 0.131 0.0
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ILE B:619 B:1367 19.0 0.109 E -124.8 107.8 19.0 0.109 0.0
ILE D:619 D:1367 20.0 0.114 E -126.7 106.6 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ILE B:619 B:1367 26.0 0.149 E -124.2 123.3 26.0 0.149 0.0 HOH
 3.931
 CA
 O
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 ILE B:619 B:1367 24.0 0.137 E -117.9 121.6 24.0 0.137 0.0
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 ILE B:619 B:1367 24.0 0.137 E -117.9 121.6 24.0 0.137 0.0
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 ILE B:616 B:1345 25.0 0.143 E -118.3 119.0 25.0 0.143 0.0
ILE D:616 D:1345 25.0 0.143 E -117.5 119.3 NA NA NA
2a74 3 P01024 100.0 0.0 X-RAY
 2005-09-27 ILE C:47 C:1345 27.0 0.154 E -127.7 126.1 27.0 0.154 0.0 HOH
 3.862
 CG2
 O
ILE F:47 F:1345 23.0 0.131 E -129.4 120.9 NA NA NA
2ice 3 P01024 100.0 0.0 X-RAY
 2006-11-07 ILE C:47 C:1345 5.0 0.029 E -124.4 124.9 5.0 0.029 0.0
ILE G:47 F:1345 23.0 0.131 E -105.5 113.6 NA NA NA
2qki 3 P01024 100.0 0.0 X-RAY
 2007-08-14 ILE C:47 C:1345 15.0 0.086 E -125.8 118.5 15.0 0.086 0.0 HOH
 3.087
 N
 O
ILE F:47 F:1345 20.0 0.114 E -126.2 122.1 NA NA NA
3l3o 4 P01024 100.0 0.0 X-RAY
 2010-08-04 ILE E:47 F:1345 29.0 0.166 E -102.5 90.4 NA NA NA
ILE G:47 C:1345 30.0 0.171 E -102.5 90.4 30.0 0.171 0.0
3nms 2 P01024 100.0 0.0 X-RAY
 2010-08-04 ILE B:47 C:1345 31.0 0.177 E -115.7 98.3 31.0 0.177 0.0
3ohx 3 P01024 100.0 0.0 X-RAY
 2010-09-01 ILE C:47 C:1345 29.0 0.166 E -102.5 90.4 29.0 0.166 0.0
ILE G:47 F:1345 30.0 0.171 E -102.5 90.4 NA NA NA
3t4a 3 P01024 100.0 0.0 X-RAY
 2011-11-23 ILE C:47 C:1345 30.0 0.171 E -121.9 113.1 30.0 0.171 0.0
ILE F:47 F:1345 35.0 0.2 E -126.7 115.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 ILE A:1367 A:1367 24.0 0.137 E -115.6 138.4