Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6685112 . C A CCDS32883.1:NM_000064.2:c.3856Gcc>Tcc_NP_000055.2:p.1286A>S Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 ALA B:615 B:1286 48.0 0.417 -119.3 65.9 48.0 0.417 0.0
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 ALA B:614 B:1264 34.0 0.296 -71.6 129.9 34.0 0.296 0.0
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 ALA B:538 B:1264 9.0 0.078 S -57.3 143.2 9.0 0.078 0.0
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 ALA B:538 B:1264 27.0 0.235 S -52.5 124.9 27.0 0.235 0.0 GOL
HOH
 8.163
8.633
 N
CB
 O2
O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 ALA B:538 B:1264 27.0 0.235 -68.1 131.5 27.0 0.235 0.0
ALA D:538 D:1264 24.0 0.209 -66.7 131.1 NA NA NA
ALA F:538 F:1264 25.0 0.217 -66.9 131.1 NA NA NA
ALA H:538 H:1264 33.0 0.287 -58.6 -174.0 33.0 0.287 0.0
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 ALA B:538 B:1264 4.0 0.035 S -62.6 130.8 4.0 0.035 0.0
ALA D:538 D:1264 26.0 0.226 -134.7 126.2 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 ALA B:538 B:1264 12.0 0.104 -29.8 119.8 12.0 0.104 0.0
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 ALA B:538 B:1286 22.0 0.191 -65.2 122.0 22.0 0.191 0.0
ALA G:538 F:1286 26.0 0.226 -65.0 122.2 26.0 0.226 0.0
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 ALA B:538 B:1286 19.0 0.165 -64.8 122.2 19.0 0.165 0.0
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 ALA F:538 B:1264 33.0 0.287 -53.7 129.9 33.0 0.287 0.0
ALA H:538 H:1264 54.0 0.47 24.6 90.3 54.0 0.47 0.0
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 ALA H:538 B:1264 34.0 0.296 -70.4 142.4 34.0 0.296 0.0
ALA J:538 H:1264 33.0 0.287 -69.3 144.0 33.0 0.287 0.0
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 ALA B:538 B:1264 13.0 0.113 S -66.4 128.1 13.0 0.113 0.0 HOH
 5.989
 O
 O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 ALA B:538 B:1264 36.0 0.313 -60.8 155.3 36.0 0.313 0.0
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 ALA B:538 B:1264 20.0 0.174 -69.7 120.3 20.0 0.174 0.0
ALA D:538 D:1264 18.0 0.157 -68.2 111.2 NA NA NA
ALA F:538 F:1264 17.0 0.148 -69.7 115.2 NA NA NA
ALA H:538 H:1264 8.0 0.07 S -69.6 110.4 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ALA B:538 B:1286 64.0 0.557 -65.2 120.1 64.0 0.557 0.0
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ALA B:538 B:1286 24.0 0.209 -64.6 131.3 24.0 0.209 0.0 HOH
 5.412
 CB
 O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ALA B:538 B:1286 19.0 0.165 -75.9 121.0 NA NA NA
ALA E:538 E:1286 18.0 0.157 -77.7 120.8 18.0 0.157 0.0
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ALA B:538 B:1286 19.0 0.165 71.6 16.3 19.0 0.165 0.0
ALA D:538 D:1286 46.0 0.4 64.6 26.7 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ALA B:538 B:1286 20.0 0.174 -65.8 134.1 20.0 0.174 0.0 HOH
 8.895
 N
 O
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 ALA B:538 B:1286 45.0 0.391 -154.0 139.9 45.0 0.391 0.0
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 ALA B:538 B:1286 48.0 0.417 -154.0 139.9 48.0 0.417 0.0
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 ALA B:535 B:1264 16.0 0.139 -97.5 110.9 16.0 0.139 0.0
ALA D:535 D:1264 17.0 0.148 -100.4 105.9 NA NA NA
6rmt 1 P01024 99.68 0.0 X-RAY
 2020-11-18 ALA A:293 A:293 23.0 0.2 S -123.2 70.0 23.0 0.2 0.0 HOH
 2.764
 HA
 O
ALA B:293 B:293 0.0 0.0 -154.5 49.7 0.0 0.0 0.0 HOH
 2.981
 HA
 O
6rmu 1 P01024 99.68 0.0 X-RAY
 2020-11-18 ALA A:293 A:293 12.0 0.104 G -68.9 -45.5 12.0 0.104 0.0 HOH
 5.989
 HB3
 O
ALA C:293 B:293 5.0 0.043 S -67.6 -42.6 5.0 0.043 0.0 HOH
 6.208
 H
 O
2wy7 1 P01024 99.35 0.0 X-RAY
 2010-12-01 ALA A:293 A:300 36.0 0.313 -59.7 122.1 36.0 0.313 0.0 HOH
 6.074
 N
 O
2wy8 1 P01024 99.35 0.0 X-RAY
 2010-12-01 ALA A:293 A:300 37.0 0.322 -61.6 123.0 37.0 0.322 0.0 HOH
 4.731
 CB
 O
3oed 1 P01024 99.35 0.0 X-RAY
 2011-05-11 ALA A:293 A:293 47.0 0.409 -56.8 105.9 40.0 0.348 0.061 B:P20023:0.061
 HOH
 6.820
 N
 O
ALA C:293 B:293 59.0 0.513 -58.8 108.6 NA NA NA
3oxu 1 P01024 99.68 0.0 X-RAY
 2011-02-16 ALA A:300 A:293 40.0 0.348 -43.4 123.2 NA NA NA
ALA B:300 B:293 9.0 0.078 S -83.1 125.0 9.0 0.078 0.0 HOH
 2.808
 O
 O
ALA C:300 C:293 59.0 0.513 -77.5 -53.3 NA NA NA
3rj3 1 P01024 99.68 0.0 X-RAY
 2012-03-14 ALA A:300 A:293 33.0 0.287 -50.8 130.6 33.0 0.287 0.0 HOH
 9.642
 O
 O
ALA B:300 B:293 12.0 0.104 S -69.0 126.3 NA NA NA
ALA C:300 C:293 49.0 0.426 -79.5 -51.4 NA NA NA
4ont 2 P01024 99.68 0.0 X-RAY
 2014-11-26 ALA B:300 A:293 77.0 0.67 -56.8 100.0 NA NA NA
ALA D:300 B:293 9.0 0.078 S -93.3 126.6 9.0 0.078 0.0 HOH
 2.814
 O
 O
ALA F:300 C:293 52.0 0.452 -100.8 107.4 NA NA NA
4zh1 1 P01024 99.68 0.0 X-RAY
 2016-01-13 ALA A:300 A:293 34.0 0.296 -57.3 139.6 34.0 0.296 0.0 HOH
 8.091
 N
 O
ALA B:300 B:293 9.0 0.078 S -83.6 124.3 NA NA NA
ALA C:300 C:293 40.0 0.348 -58.4 -70.9 NA NA NA
1ghq 1 P01024 99.02 0.0 X-RAY
 2001-06-13 ALA A:293 A:293 28.0 0.243 G -47.9 -44.3 28.0 0.243 0.0 HOH
 2.685
 O
 O
4m76 1 P01024 99.66 0.0 X-RAY
 2013-10-02 ALA A:296 A:1286 29.0 0.252 -70.8 127.2 29.0 0.252 0.0 NI
HOH
 5.958
5.614
 CB
CB
 NI
O
5nbq 1 P01024 99.66 0.0 X-RAY
 2017-12-06 ALA A:293 NA:NA DO NA DO DO DO NA NA NA
ALA B:293 B:1286 69.0 0.6 -99.7 -172.6 NA NA NA
ALA C:293 C:1286 115.0 1.0 -170.1 360.0 NA NA NA
2gox 1 P01024 98.98 0.0 X-RAY
 2007-03-20 ALA A:296 A:1286 17.0 0.148 -73.0 137.6 17.0 0.148 0.0 HOH
 3.354
 O
 O
ALA C:296 C:1286 23.0 0.2 -72.5 133.0 NA NA NA
2noj 1 P01024 98.98 0.0 X-RAY
 2007-08-14 ALA A:296 A:1286 72.0 0.626 -111.4 360.0 72.0 0.626 0.0 HOH
 3.435
 CA
 O
ALA C:296 C:1286 75.0 0.652 -106.4 -51.0 NA NA NA
ALA E:296 E:1286 39.0 0.339 -60.0 133.8 NA NA NA
ALA G:296 G:1286 86.0 0.748 -75.8 360.0 NA NA NA
3d5r 1 P01024 98.98 0.0 X-RAY
 2008-09-09 ALA A:296 A:297 16.0 0.139 -28.3 135.6 16.0 0.139 0.0 HOH
 7.423
 N
 O
ALA C:296 B:297 18.0 0.157 -32.2 136.4 NA NA NA
3d5s 1 P01024 98.98 0.0 X-RAY
 2008-09-16 ALA A:296 A:297 18.0 0.157 -36.3 137.0 18.0 0.157 0.0 HOH
 7.529
 N
 O
ALA C:296 B:297 18.0 0.157 -35.2 136.3 NA NA NA
1c3d 1 P01024 99.32 0.0 X-RAY
 1998-10-07 ALA A:293 A:293 24.0 0.209 -73.7 120.1 24.0 0.209 0.0 HOH
 4.899
 N
 O
2xqw 1 P01024 99.32 0.0 X-RAY
 2011-02-02 ALA A:293 A:293 85.0 0.739 -104.3 88.2 85.0 0.739 0.0
ALA B:293 B:293 82.0 0.713 -120.3 77.8 82.0 0.713 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 ALA A:1286 A:1286 20.0 0.174 S -130.8 78.0