Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6685157 . C A CCDS32883.1:NM_000064.2:c.3811Gcc>Tcc_NP_000055.2:p.1271A>S Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 ALA B:600 B:1271 0.0 0.0 H -61.4 -52.6 0.0 0.0 0.0
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 ALA B:599 B:1249 1.0 0.009 H -62.1 -51.1 1.0 0.009 0.0
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 ALA B:523 B:1249 1.0 0.009 H -42.4 -48.0 1.0 0.009 0.0
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 ALA B:523 B:1249 2.0 0.017 H -63.2 -44.3 2.0 0.017 0.0 HOH
 3.406
 CB
 O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 ALA B:523 B:1249 4.0 0.035 H -62.6 -32.5 4.0 0.035 0.0
ALA D:523 D:1249 3.0 0.026 H -62.6 -32.6 NA NA NA
ALA F:523 F:1249 4.0 0.035 H -62.6 -32.4 NA NA NA
ALA H:523 H:1249 3.0 0.026 H -69.0 -17.3 3.0 0.026 0.0
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 ALA B:523 B:1249 4.0 0.035 H -66.6 -26.8 4.0 0.035 0.0
ALA D:523 D:1249 3.0 0.026 H -48.2 -56.5 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 ALA B:523 B:1249 1.0 0.009 H -66.4 -17.1 1.0 0.009 0.0
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 ALA B:523 B:1271 3.0 0.026 H -64.8 -22.3 3.0 0.026 0.0
ALA G:523 F:1271 4.0 0.035 H -65.0 -22.4 4.0 0.035 0.0
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 ALA B:523 B:1271 4.0 0.035 H -64.7 -22.0 4.0 0.035 0.0
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 ALA F:523 B:1249 3.0 0.026 H -65.3 -43.4 3.0 0.026 0.0
ALA H:523 H:1249 4.0 0.035 H -63.6 -44.2 4.0 0.035 0.0
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 ALA H:523 B:1249 3.0 0.026 H -68.5 -42.4 3.0 0.026 0.0
ALA J:523 H:1249 1.0 0.009 H -68.2 -42.4 1.0 0.009 0.0
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 ALA B:523 B:1249 3.0 0.026 H -62.3 -39.6 3.0 0.026 0.0 HOH
 2.952
 N
 O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 ALA B:523 B:1249 3.0 0.026 H -51.8 -42.1 3.0 0.026 0.0
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 ALA B:523 B:1249 0.0 0.0 H -55.2 -48.1 0.0 0.0 0.0
ALA D:523 D:1249 0.0 0.0 H -55.3 -48.2 NA NA NA
ALA F:523 F:1249 0.0 0.0 H -55.4 -48.2 NA NA NA
ALA H:523 H:1249 0.0 0.0 H -55.2 -47.9 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ALA B:523 B:1271 4.0 0.035 H -65.0 -22.1 4.0 0.035 0.0
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ALA B:523 B:1271 3.0 0.026 H -63.8 -41.5 3.0 0.026 0.0 EDO
EDO
HOH
 9.950
7.770
3.056
 C
O
N
 O1
C2
O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ALA B:523 B:1271 2.0 0.017 H -57.9 -55.6 NA NA NA
ALA E:523 E:1271 2.0 0.017 H -58.1 -55.0 2.0 0.017 0.0
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ALA B:523 B:1271 2.0 0.017 H -50.5 -41.2 2.0 0.017 0.0
ALA D:523 D:1271 0.0 0.0 H -52.2 -42.3 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ALA B:523 B:1271 5.0 0.043 H -63.5 -41.1 5.0 0.043 0.0 HOH
 4.687
 N
 O
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 ALA B:523 B:1271 2.0 0.017 H -66.8 -35.3 2.0 0.017 0.0
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 ALA B:523 B:1271 2.0 0.017 H -66.7 -35.3 2.0 0.017 0.0
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 ALA B:520 B:1249 0.0 0.0 H -70.2 -25.0 0.0 0.0 0.0
ALA D:520 D:1249 0.0 0.0 H -71.8 -24.0 NA NA NA
6rmt 1 P01024 99.68 0.0 X-RAY
 2020-11-18 ALA A:278 A:278 3.0 0.026 H -62.2 -38.2 3.0 0.026 0.0 HOH
 2.183
 H
 O
ALA B:278 B:278 3.0 0.026 H -57.8 -41.2 3.0 0.026 0.0 HOH
 2.122
 H
 O
6rmu 1 P01024 99.68 0.0 X-RAY
 2020-11-18 ALA A:278 A:278 4.0 0.035 H -65.5 -41.9 4.0 0.035 0.0 HOH
 2.004
 H
 O
ALA C:278 B:278 3.0 0.026 H -63.9 -36.3 3.0 0.026 0.0 HOH
 2.028
 H
 O
2wy7 1 P01024 99.35 0.0 X-RAY
 2010-12-01 ALA A:278 A:285 2.0 0.017 H -62.4 -40.1 2.0 0.017 0.0 HOH
 2.963
 N
 O
2wy8 1 P01024 99.35 0.0 X-RAY
 2010-12-01 ALA A:278 A:285 3.0 0.026 H -61.8 -40.4 3.0 0.026 0.0 HOH
 2.939
 N
 O
3oed 1 P01024 99.35 0.0 X-RAY
 2011-05-11 ALA A:278 A:278 1.0 0.009 H -55.3 -38.6 1.0 0.009 0.0
ALA C:278 B:278 4.0 0.035 H -52.1 -52.5 NA NA NA
3oxu 1 P01024 99.68 0.0 X-RAY
 2011-02-16 ALA A:285 A:278 3.0 0.026 H -58.1 -41.5 NA NA NA
ALA B:285 B:278 9.0 0.078 H -60.5 -44.8 9.0 0.078 0.0 HOH
 3.194
 N
 O
ALA C:285 C:278 3.0 0.026 H -61.3 -40.5 NA NA NA
3rj3 1 P01024 99.68 0.0 X-RAY
 2012-03-14 ALA A:285 A:278 3.0 0.026 H -54.5 -44.0 3.0 0.026 0.0 HOH
 3.175
 N
 O
ALA B:285 B:278 2.0 0.017 H -59.5 -41.0 NA NA NA
ALA C:285 C:278 3.0 0.026 H -57.5 -42.9 NA NA NA
4ont 2 P01024 99.68 0.0 X-RAY
 2014-11-26 ALA B:285 A:278 3.0 0.026 H -54.8 -44.8 NA NA NA
ALA D:285 B:278 8.0 0.07 H -58.3 -46.2 8.0 0.07 0.0 HOH
 3.011
 N
 O
ALA F:285 C:278 3.0 0.026 H -56.5 -46.5 NA NA NA
4zh1 1 P01024 99.68 0.0 X-RAY
 2016-01-13 ALA A:285 A:278 3.0 0.026 H -51.8 -44.7 3.0 0.026 0.0 HOH
 2.977
 N
 O
ALA B:285 B:278 9.0 0.078 H -51.3 -44.7 NA NA NA
ALA C:285 C:278 4.0 0.035 H -52.7 -44.9 NA NA NA
1ghq 1 P01024 99.02 0.0 X-RAY
 2001-06-13 ALA A:278 A:278 26.0 0.226 H -60.6 -42.1 26.0 0.226 0.0 HOH
 3.110
 N
 O
4m76 1 P01024 99.66 0.0 X-RAY
 2013-10-02 ALA A:281 A:1271 3.0 0.026 H -62.1 -41.0 3.0 0.026 0.0 HOH
 3.063
 N
 O
5nbq 1 P01024 99.66 0.0 X-RAY
 2017-12-06 ALA A:278 A:1271 2.0 0.017 H -55.4 -47.4 2.0 0.017 0.0
ALA B:278 B:1271 2.0 0.017 H -58.0 -47.9 NA NA NA
ALA C:278 C:1271 3.0 0.026 H -55.1 -47.6 NA NA NA
2gox 1 P01024 98.98 0.0 X-RAY
 2007-03-20 ALA A:281 A:1271 3.0 0.026 H -58.5 -41.0 3.0 0.026 0.0 HOH
 2.809
 N
 O
ALA C:281 C:1271 3.0 0.026 H -66.1 -38.7 NA NA NA
2noj 1 P01024 98.98 0.0 X-RAY
 2007-08-14 ALA A:281 A:1271 14.0 0.122 H -60.3 -52.1 14.0 0.122 0.0 HOH
 4.618
 N
 O
ALA C:281 C:1271 9.0 0.078 H -70.4 -56.3 NA NA NA
ALA E:281 E:1271 2.0 0.017 H -70.5 -53.0 NA NA NA
ALA G:281 G:1271 4.0 0.035 H -65.7 -43.8 NA NA NA
3d5r 1 P01024 98.98 0.0 X-RAY
 2008-09-09 ALA A:281 A:282 3.0 0.026 H -64.2 -37.5 3.0 0.026 0.0 HOH
 3.180
 N
 O
ALA C:281 B:282 3.0 0.026 H -65.1 -35.2 NA NA NA
3d5s 1 P01024 98.98 0.0 X-RAY
 2008-09-16 ALA A:281 A:282 3.0 0.026 H -62.4 -42.4 3.0 0.026 0.0 HOH
 3.008
 N
 O
ALA C:281 B:282 3.0 0.026 H -66.8 -39.3 NA NA NA
1c3d 1 P01024 99.32 0.0 X-RAY
 1998-10-07 ALA A:278 A:278 3.0 0.026 H -62.8 -38.7 3.0 0.026 0.0 GOL
HOH
 9.523
2.891
 C
N
 O3
O
2xqw 1 P01024 99.32 0.0 X-RAY
 2011-02-02 ALA A:278 A:278 3.0 0.026 H -61.3 -39.3 3.0 0.026 0.0 HOH
 2.820
 N
 O
ALA B:278 B:278 4.0 0.035 H -69.7 -31.8 4.0 0.035 0.0 HOH
 2.807
 N
 O
1qqf 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 ALA A:262 A:1271 3.0 0.026 H -57.8 -41.1 3.0 0.026 0.0 HOH
 2.954
 N
 O
1qsj 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 ALA A:262 A:1271 2.0 0.017 H -72.5 -28.6 2.0 0.017 0.0 HOH
 3.444
 CB
 O
ALA B:262 B:1271 2.0 0.017 H -72.6 -27.8 2.0 0.017 0.0 HOH
 3.084
 N
 O
ALA C:262 C:1271 2.0 0.017 H -72.5 -28.9 NA NA NA
ALA D:262 D:1271 2.0 0.017 H -72.2 -29.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 ALA A:1271 A:1271 1.0 0.009 H -58.1 -53.3