Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6686157 . C A CCDS32883.1:NM_000064.2:c.3788gGt>gTt_NP_000055.2:p.1263G>V Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 GLY B:592 B:1263 12.0 0.16 T 68.8 -164.4 12.0 0.16 0.0 NAG
NAG
 5.887
9.269
 CA
CA
 O7
O6
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 GLY B:591 B:1241 15.0 0.2 S 60.0 -166.6 15.0 0.2 0.0 NAG
 5.962
 CA
 O7
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 GLY B:515 B:1241 9.0 0.12 47.3 -153.9 9.0 0.12 0.0
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 GLY B:515 B:1241 10.0 0.133 72.4 175.3 10.0 0.133 0.0 HOH
 5.977
 C
 O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 GLY B:515 B:1241 10.0 0.133 68.1 -174.9 10.0 0.133 0.0
GLY D:515 D:1241 11.0 0.147 68.2 -175.0 NA NA NA
GLY F:515 F:1241 11.0 0.147 68.1 -175.0 NA NA NA
GLY H:515 H:1241 12.0 0.16 70.2 -172.7 12.0 0.16 0.0
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 GLY B:515 B:1241 12.0 0.16 76.2 -159.5 12.0 0.16 0.0
GLY D:515 D:1241 13.0 0.173 69.2 -174.8 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 GLY B:515 B:1241 13.0 0.173 84.8 -165.9 13.0 0.173 0.0
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 GLY B:515 B:1263 7.0 0.093 70.8 175.3 7.0 0.093 0.0
GLY G:515 F:1263 9.0 0.12 71.2 175.9 9.0 0.12 0.0
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 GLY B:515 B:1263 11.0 0.147 71.1 175.3 11.0 0.147 0.0
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 GLY F:515 B:1241 14.0 0.187 69.6 -179.1 14.0 0.187 0.0
GLY H:515 H:1241 15.0 0.2 71.4 -179.8 15.0 0.2 0.0
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 GLY H:515 B:1241 17.0 0.227 73.9 -177.5 17.0 0.227 0.0
GLY J:515 H:1241 15.0 0.2 73.2 -176.2 15.0 0.2 0.0
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 GLY B:515 B:1241 11.0 0.147 74.9 175.5 11.0 0.147 0.0 HOH
 4.541
 C
 O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 GLY B:515 B:1241 7.0 0.093 61.9 -175.5 7.0 0.093 0.0
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 GLY B:515 B:1241 13.0 0.173 62.7 -164.2 13.0 0.173 0.0
GLY D:515 D:1241 13.0 0.173 61.9 -164.2 NA NA NA
GLY F:515 F:1241 13.0 0.173 61.8 -164.0 NA NA NA
GLY H:515 H:1241 14.0 0.187 63.0 -164.1 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 GLY B:515 B:1263 11.0 0.147 71.4 175.8 11.0 0.147 0.0
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 GLY B:515 B:1263 9.0 0.12 77.9 165.9 9.0 0.12 0.0 EDO
EDO
HOH
 6.039
6.839
3.505
 C
N
O
 C1
C1
O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 GLY B:515 B:1263 15.0 0.2 70.1 -173.5 NA NA NA
GLY E:515 E:1263 16.0 0.213 69.7 -172.5 16.0 0.213 0.0
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 GLY B:515 B:1263 9.0 0.12 57.2 -170.4 9.0 0.12 0.0
GLY D:515 D:1263 6.0 0.08 S 57.4 -175.8 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 GLY B:515 B:1263 9.0 0.12 62.2 -169.1 9.0 0.12 0.0 GOL
GOL
HOH
 4.980
3.588
9.480
 O
O
C
 O1
O1
O
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 GLY B:515 B:1263 11.0 0.147 74.1 -175.0 11.0 0.147 0.0
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 GLY B:515 B:1263 11.0 0.147 74.1 -175.0 11.0 0.147 0.0
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 GLY B:512 B:1241 12.0 0.16 56.1 -164.3 12.0 0.16 0.0
GLY D:512 D:1241 12.0 0.16 57.1 -164.4 NA NA NA
6rmt 1 P01024 99.68 0.0 X-RAY
 2020-11-18 GLY A:270 A:270 10.0 0.133 76.2 172.6 10.0 0.133 0.0 HOH
 3.747
 H
 O
GLY B:270 B:270 9.0 0.12 76.2 173.7 9.0 0.12 0.0 HOH
 3.573
 H
 O
6rmu 1 P01024 99.68 0.0 X-RAY
 2020-11-18 GLY A:270 A:270 28.0 0.373 76.2 169.7 12.0 0.16 0.213 C:P01024:0.213
 HOH
 5.255
 C
 O
GLY C:270 B:270 25.0 0.333 84.6 174.0 11.0 0.147 0.186 A:P01024:0.187
 HOH
 4.922
 C
 O
2wy7 1 P01024 99.35 0.0 X-RAY
 2010-12-01 GLY A:270 A:277 14.0 0.187 78.2 175.7 14.0 0.187 0.0 HOH
 3.757
 O
 O
2wy8 1 P01024 99.35 0.0 X-RAY
 2010-12-01 GLY A:270 A:277 13.0 0.173 78.7 176.8 13.0 0.173 0.0 HOH
 3.846
 O
 O
3oed 1 P01024 99.35 0.0 X-RAY
 2011-05-11 GLY A:270 A:270 6.0 0.08 S 67.5 169.2 6.0 0.08 0.0
GLY C:270 B:270 10.0 0.133 69.6 174.0 NA NA NA
3oxu 1 P01024 99.68 0.0 X-RAY
 2011-02-16 GLY A:277 A:270 10.0 0.133 83.7 170.0 NA NA NA
GLY B:277 B:270 67.0 0.893 360.0 118.2 67.0 0.893 0.0 HOH
 2.971
 N
 O
GLY C:277 C:270 12.0 0.16 81.4 -179.1 NA NA NA
3rj3 1 P01024 99.68 0.0 X-RAY
 2012-03-14 GLY A:277 A:270 10.0 0.133 75.3 175.3 5.0 0.067 0.066 D:Q03591:0.067
 HOH
 4.953
 C
 O
GLY B:277 B:270 5.0 0.067 -126.3 58.9 NA NA NA
GLY C:277 C:270 11.0 0.147 83.4 -170.5 NA NA NA
4ont 2 P01024 99.68 0.0 X-RAY
 2014-11-26 GLY B:277 A:270 12.0 0.16 80.0 169.6 NA NA NA
GLY D:277 NA:NA DO NA DO DO DO NA NA NA
GLY F:277 C:270 10.0 0.133 67.1 169.5 NA NA NA
4zh1 1 P01024 99.68 0.0 X-RAY
 2016-01-13 GLY A:277 A:270 12.0 0.16 80.5 174.6 12.0 0.16 0.0 HOH
 2.477
 O
 O
GLY B:277 NA:NA DO NA DO DO DO NA NA NA
GLY C:277 C:270 17.0 0.227 82.6 175.1 NA NA NA
1ghq 1 P01024 99.02 0.0 X-RAY
 2001-06-13 GLY A:270 A:270 25.0 0.333 -52.3 -37.0 25.0 0.333 0.0 HOH
 3.499
 C
 O
4m76 1 P01024 99.66 0.0 X-RAY
 2013-10-02 GLY A:273 A:1263 11.0 0.147 77.7 -174.8 11.0 0.147 0.0 HOH
 5.852
 C
 O
5nbq 1 P01024 99.66 0.0 X-RAY
 2017-12-06 GLY A:270 A:1263 11.0 0.147 65.1 -172.3 11.0 0.147 0.0
GLY B:270 B:1263 10.0 0.133 65.3 -173.5 NA NA NA
GLY C:270 C:1263 10.0 0.133 66.2 -173.2 NA NA NA
2gox 1 P01024 98.98 0.0 X-RAY
 2007-03-20 GLY A:273 A:1263 11.0 0.147 67.7 176.7 11.0 0.147 0.0 HOH
 3.276
 O
 O
GLY C:273 C:1263 12.0 0.16 61.7 -178.4 NA NA NA
2noj 1 P01024 98.98 0.0 X-RAY
 2007-08-14 GLY A:273 NA:NA DO NA DO DO DO NA NA NA
GLY C:273 NA:NA DO NA DO DO DO NA NA NA
GLY E:273 E:1263 5.0 0.067 68.2 158.9 NA NA NA
GLY G:273 G:1263 7.0 0.093 85.3 177.3 NA NA NA
3d5r 1 P01024 98.98 0.0 X-RAY
 2008-09-09 GLY A:273 A:274 11.0 0.147 64.1 -178.9 11.0 0.147 0.0 HOH
 4.961
 C
 O
GLY C:273 B:274 11.0 0.147 65.2 179.8 NA NA NA
3d5s 1 P01024 98.98 0.0 X-RAY
 2008-09-16 GLY A:273 A:274 11.0 0.147 62.6 -178.6 11.0 0.147 0.0 HOH
 5.052
 C
 O
GLY C:273 B:274 11.0 0.147 63.5 179.4 NA NA NA
1c3d 1 P01024 99.32 0.0 X-RAY
 1998-10-07 GLY A:270 A:270 8.0 0.107 71.0 175.4 8.0 0.107 0.0 GOL
HOH
 5.635
4.672
 C
O
 O3
O
2xqw 1 P01024 99.32 0.0 X-RAY
 2011-02-02 GLY A:270 A:270 10.0 0.133 72.5 172.5 10.0 0.133 0.0 HOH
 4.328
 C
 O
GLY B:270 B:270 11.0 0.147 S 77.5 177.8 11.0 0.147 0.0 HOH
 2.631
 O
 O
1qqf 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 GLY A:254 A:1263 38.0 0.507 T -53.2 139.8 1.0 0.013 0.494 A:P01026:0.493
 HOH
 2.719
 O
 O
1qsj 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 GLY A:254 A:1263 34.0 0.453 T -12.0 -86.8 11.0 0.147 0.306 B:P01026:0.307
 HOH
 2.963
 N
 O
GLY B:254 B:1263 34.0 0.453 T -11.6 -86.0 14.0 0.187 0.266 A:P01026:0.267
 HOH
 3.075
 N
 O
GLY C:254 C:1263 33.0 0.44 T -12.6 -86.6 NA NA NA
GLY D:254 D:1263 17.0 0.227 T -5.8 -90.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 GLY A:1263 A:1263 38.0 0.507 T 63.7 19.9