Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6686191 . C A CCDS32883.1:NM_000064.2:c.3754Gtc>Ttc_NP_000055.2:p.1252V>F Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 VAL B:581 B:1252 1.0 0.006 H -68.2 -36.6 1.0 0.006 0.0
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 VAL B:580 B:1230 0.0 0.0 H -72.2 -45.8 0.0 0.0 0.0
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 VAL B:504 B:1230 0.0 0.0 H -56.3 -37.9 0.0 0.0 0.0
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 VAL B:504 B:1230 0.0 0.0 H -64.5 -47.2 0.0 0.0 0.0 GOL
HOH
 9.834
4.792
 O
N
 O3
O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 VAL B:504 B:1230 0.0 0.0 H -67.6 -49.6 0.0 0.0 0.0
VAL D:504 D:1230 0.0 0.0 H -67.7 -49.6 NA NA NA
VAL F:504 F:1230 0.0 0.0 H -67.6 -49.6 NA NA NA
VAL H:504 H:1230 0.0 0.0 H -69.5 -49.0 0.0 0.0 0.0
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 VAL B:504 B:1230 0.0 0.0 H -69.1 -46.9 0.0 0.0 0.0
VAL D:504 D:1230 0.0 0.0 H -72.5 -52.5 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 VAL B:504 B:1230 0.0 0.0 H -60.9 -22.7 0.0 0.0 0.0
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 VAL B:504 B:1252 0.0 0.0 H -57.3 -57.0 0.0 0.0 0.0
VAL G:504 F:1252 0.0 0.0 H -57.5 -57.4 0.0 0.0 0.0
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 VAL B:504 B:1252 0.0 0.0 H -57.1 -57.2 0.0 0.0 0.0
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 VAL F:504 B:1230 0.0 0.0 H -68.7 -48.3 0.0 0.0 0.0
VAL H:504 H:1230 0.0 0.0 H -69.3 -48.6 0.0 0.0 0.0
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 VAL H:504 B:1230 0.0 0.0 H -71.3 -45.4 0.0 0.0 0.0
VAL J:504 H:1230 0.0 0.0 H -72.2 -45.0 0.0 0.0 0.0
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 VAL B:504 B:1230 0.0 0.0 H -71.7 -47.7 0.0 0.0 0.0 HOH
 5.110
 N
 O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 VAL B:504 B:1230 0.0 0.0 H -70.1 -35.9 0.0 0.0 0.0
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 VAL B:504 B:1230 0.0 0.0 H -70.8 -56.8 0.0 0.0 0.0
VAL D:504 D:1230 0.0 0.0 H -70.8 -56.6 NA NA NA
VAL F:504 F:1230 0.0 0.0 H -71.0 -56.9 NA NA NA
VAL H:504 H:1230 0.0 0.0 H -71.6 -56.4 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 VAL B:504 B:1252 0.0 0.0 H -56.7 -57.4 0.0 0.0 0.0
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 VAL B:504 B:1252 0.0 0.0 H -63.8 -47.9 0.0 0.0 0.0 EDO
EDO
HOH
 9.836
8.481
4.528
 CG2
O
CG2
 C1
C2
O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 VAL B:504 B:1252 0.0 0.0 H -70.9 -51.9 NA NA NA
VAL E:504 E:1252 0.0 0.0 H -70.8 -51.3 0.0 0.0 0.0
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 VAL B:504 B:1252 0.0 0.0 H -77.0 -55.1 0.0 0.0 0.0
VAL D:504 D:1252 6.0 0.039 H -72.6 -37.1 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 VAL B:504 B:1252 0.0 0.0 H -64.3 -45.5 0.0 0.0 0.0
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 VAL B:504 B:1252 0.0 0.0 H -75.0 -45.3 0.0 0.0 0.0
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 VAL B:504 B:1252 0.0 0.0 H -75.0 -45.3 0.0 0.0 0.0
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 VAL B:501 B:1230 0.0 0.0 H -67.5 -51.2 0.0 0.0 0.0
VAL D:501 D:1230 0.0 0.0 H -69.2 -50.1 NA NA NA
6rmt 1 P01024 99.68 0.0 X-RAY
 2020-11-18 VAL A:259 A:259 0.0 0.0 H -70.7 -47.8 0.0 0.0 0.0 HOH
 3.807
 HG23
 O
VAL B:259 B:259 0.0 0.0 H -65.8 -48.6 0.0 0.0 0.0 HOH
 3.746
 HG23
 O
6rmu 1 P01024 99.68 0.0 X-RAY
 2020-11-18 VAL A:259 A:259 0.0 0.0 H -71.0 -44.6 0.0 0.0 0.0 HOH
 3.634
 HG23
 O
VAL C:259 B:259 0.0 0.0 H -73.6 -45.0 0.0 0.0 0.0 HOH
 3.948
 HG23
 O
2wy7 1 P01024 99.35 0.0 X-RAY
 2010-12-01 VAL A:259 A:266 0.0 0.0 H -69.0 -49.2 0.0 0.0 0.0 HOH
 4.506
 CG2
 O
2wy8 1 P01024 99.35 0.0 X-RAY
 2010-12-01 VAL A:259 A:266 0.0 0.0 H -70.4 -48.1 0.0 0.0 0.0 HOH
 4.479
 CG2
 O
3oed 1 P01024 99.35 0.0 X-RAY
 2011-05-11 VAL A:259 A:259 0.0 0.0 H -74.9 -60.4 0.0 0.0 0.0
VAL C:259 B:259 0.0 0.0 H -73.6 -59.3 NA NA NA
3oxu 1 P01024 99.68 0.0 X-RAY
 2011-02-16 VAL A:266 A:259 0.0 0.0 H -72.7 -50.9 NA NA NA
VAL B:266 B:259 0.0 0.0 H -58.5 -50.0 0.0 0.0 0.0 HOH
 4.750
 N
 O
VAL C:266 C:259 0.0 0.0 H -55.4 -45.7 NA NA NA
3rj3 1 P01024 99.68 0.0 X-RAY
 2012-03-14 VAL A:266 A:259 0.0 0.0 H -66.1 -49.3 0.0 0.0 0.0 HOH
 4.507
 CG2
 O
VAL B:266 B:259 0.0 0.0 H -49.7 -48.1 NA NA NA
VAL C:266 C:259 0.0 0.0 H -69.4 -52.2 NA NA NA
4ont 2 P01024 99.68 0.0 X-RAY
 2014-11-26 VAL B:266 A:259 0.0 0.0 H -66.7 -47.3 NA NA NA
VAL D:266 B:259 0.0 0.0 H -58.5 -52.4 0.0 0.0 0.0 HOH
 6.017
 N
 O
VAL F:266 C:259 0.0 0.0 H -61.5 -46.4 NA NA NA
4zh1 1 P01024 99.68 0.0 X-RAY
 2016-01-13 VAL A:266 A:259 0.0 0.0 H -66.5 -47.4 0.0 0.0 0.0 HOH
 4.618
 CG2
 O
VAL B:266 B:259 0.0 0.0 H -64.1 -48.2 NA NA NA
VAL C:266 C:259 0.0 0.0 H -65.7 -47.9 NA NA NA
1ghq 1 P01024 99.02 0.0 X-RAY
 2001-06-13 VAL A:259 A:259 0.0 0.0 H -70.3 -46.5 0.0 0.0 0.0 HOH
 4.567
 CG2
 O
4m76 1 P01024 99.66 0.0 X-RAY
 2013-10-02 VAL A:262 A:1252 0.0 0.0 H -69.8 -47.7 0.0 0.0 0.0 HOH
 4.595
 CG2
 O
5nbq 1 P01024 99.66 0.0 X-RAY
 2017-12-06 VAL A:259 A:1252 0.0 0.0 H -61.4 -52.2 0.0 0.0 0.0
VAL B:259 B:1252 0.0 0.0 H -61.4 -52.4 NA NA NA
VAL C:259 C:1252 0.0 0.0 H -61.9 -51.5 NA NA NA
2gox 1 P01024 98.98 0.0 X-RAY
 2007-03-20 VAL A:262 A:1252 0.0 0.0 H -70.6 -49.2 0.0 0.0 0.0 HOH
 4.490
 CG2
 O
VAL C:262 C:1252 0.0 0.0 H -62.8 -48.4 NA NA NA
2noj 1 P01024 98.98 0.0 X-RAY
 2007-08-14 VAL A:262 A:1252 8.0 0.052 H -43.0 -61.8 8.0 0.052 0.0
VAL C:262 C:1252 4.0 0.026 H -63.8 -42.7 NA NA NA
VAL E:262 E:1252 9.0 0.058 H -59.0 -59.7 NA NA NA
VAL G:262 G:1252 12.0 NA H -51.1 -50.4 NA NA NA
3d5r 1 P01024 98.98 0.0 X-RAY
 2008-09-09 VAL A:262 A:263 0.0 0.0 H -66.0 -48.3 0.0 0.0 0.0 HOH
 4.468
 CG2
 O
VAL C:262 B:263 0.0 0.0 H -66.2 -46.9 NA NA NA
3d5s 1 P01024 98.98 0.0 X-RAY
 2008-09-16 VAL A:262 A:263 0.0 0.0 H -66.3 -46.2 0.0 0.0 0.0 HOH
 4.647
 CG2
 O
VAL C:262 B:263 0.0 0.0 H -62.5 -46.4 NA NA NA
1c3d 1 P01024 99.32 0.0 X-RAY
 1998-10-07 VAL A:259 A:259 0.0 0.0 H -65.9 -46.6 0.0 0.0 0.0 HOH
 4.631
 N
 O
2xqw 1 P01024 99.32 0.0 X-RAY
 2011-02-02 VAL A:259 A:259 0.0 0.0 H -58.8 -43.2 0.0 0.0 0.0 HOH
 8.345
 O
 O
VAL B:259 B:259 0.0 0.0 H -65.1 -48.2 0.0 0.0 0.0
1qqf 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 VAL A:243 A:1252 1.0 0.006 H -65.0 -48.6 1.0 0.006 0.0 HOH
 3.933
 CG2
 O
1qsj 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 VAL A:243 A:1252 0.0 0.0 H -63.3 -49.4 0.0 0.0 0.0 HOH
 7.869
 O
 O
VAL B:243 B:1252 0.0 0.0 H -64.3 -48.9 0.0 0.0 0.0 HOH
 8.600
 O
 O
VAL C:243 C:1252 0.0 0.0 H -62.7 -50.2 NA NA NA
VAL D:243 D:1252 0.0 0.0 H -62.1 -49.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 VAL A:1252 A:1252 0.0 0.0 H -69.3 -46.3