Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6686274 . C A CCDS32883.1:NM_000064.2:c.3671gGt>gTt_NP_000055.2:p.1224G>V Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 GLY B:553 B:1224 33.0 0.44 T 99.8 -13.1 33.0 0.44 0.0
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 GLY B:552 B:1202 51.0 0.68 S 88.6 -39.3 51.0 0.68 0.0
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 GLY B:476 B:1202 52.0 0.693 S 153.7 -126.0 52.0 0.693 0.0
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 GLY B:476 B:1202 59.0 0.787 S 145.2 -152.8 59.0 0.787 0.0 HOH
 3.978
 C
 O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 GLY B:476 B:1202 64.0 0.853 S 173.5 -141.9 64.0 0.853 0.0
GLY D:476 D:1202 64.0 0.853 S 173.5 -141.8 NA NA NA
GLY F:476 F:1202 64.0 0.853 S 173.5 -141.8 NA NA NA
GLY H:476 H:1202 66.0 0.88 S 174.5 -141.1 66.0 0.88 0.0
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 GLY B:476 B:1202 65.0 0.867 S 122.9 -105.5 65.0 0.867 0.0
GLY D:476 D:1202 55.0 0.733 S 136.3 -163.6 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 GLY B:476 B:1202 69.0 0.92 S 110.0 -131.0 69.0 0.92 0.0
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 GLY B:476 B:1224 62.0 0.827 S 150.7 -151.6 62.0 0.827 0.0
GLY G:476 F:1224 63.0 0.84 S 150.6 -151.1 63.0 0.84 0.0
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 GLY B:476 B:1224 64.0 0.853 S 150.3 -151.4 64.0 0.853 0.0
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 GLY F:476 B:1202 66.0 0.88 S 134.3 -153.0 66.0 0.88 0.0
GLY H:476 H:1202 65.0 0.867 S 136.3 -155.3 65.0 0.867 0.0
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 GLY H:476 B:1202 67.0 0.893 S 128.9 -147.4 67.0 0.893 0.0
GLY J:476 H:1202 67.0 0.893 S 128.7 -147.4 67.0 0.893 0.0
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 GLY B:476 B:1202 59.0 0.787 S 144.9 -154.6 59.0 0.787 0.0 HOH
 2.101
 O
 O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 GLY B:476 B:1202 60.0 0.8 S -160.5 -143.6 60.0 0.8 0.0
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 GLY B:476 B:1202 48.0 0.64 S 127.5 133.6 48.0 0.64 0.0
GLY D:476 D:1202 46.0 0.613 S 127.4 133.5 NA NA NA
GLY F:476 F:1202 48.0 0.64 S 127.3 133.5 NA NA NA
GLY H:476 H:1202 47.0 0.627 S 127.4 133.7 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 GLY B:476 B:1224 63.0 0.84 S 150.0 -151.5 63.0 0.84 0.0
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 GLY B:476 B:1224 64.0 0.853 S 125.1 -159.3 64.0 0.853 0.0 EDO
HOH
 3.319
3.150
 O
C
 O1
O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 GLY B:476 B:1224 57.0 0.76 S 147.8 -163.2 NA NA NA
GLY E:476 E:1224 63.0 0.84 S 148.3 -162.6 63.0 0.84 0.0
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 GLY B:476 B:1224 60.0 0.8 S 123.3 -143.5 60.0 0.8 0.0
GLY D:476 D:1224 64.0 0.853 S 131.3 -146.3 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 GLY B:476 B:1224 68.0 0.907 S 133.0 -149.5 68.0 0.907 0.0
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 GLY B:476 B:1224 35.0 0.467 S 143.5 -178.1 35.0 0.467 0.0
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 GLY B:476 B:1224 38.0 0.507 S 143.5 -178.1 38.0 0.507 0.0
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 GLY B:473 B:1202 45.0 0.6 S 121.4 135.3 45.0 0.6 0.0
GLY D:473 D:1202 44.0 0.587 S 122.4 136.1 NA NA NA
6rmt 1 P01024 99.68 0.0 X-RAY
 2020-11-18 GLY A:231 A:231 77.0 1.0 T 90.4 -1.2 77.0 1.0 0.0 HOH
 2.195
 H
 O
GLY B:231 B:231 57.0 0.76 S 159.0 -158.0 57.0 0.76 0.0 HOH
 2.763
 O
 O
6rmu 1 P01024 99.68 0.0 X-RAY
 2020-11-18 GLY A:231 A:231 62.0 0.827 S 139.6 -161.2 62.0 0.827 0.0 HOH
 2.917
 HA3
 O
GLY C:231 B:231 63.0 0.84 S 126.4 -163.0 63.0 0.84 0.0 HOH
 2.996
 HA3
 O
2wy7 1 P01024 99.35 0.0 X-RAY
 2010-12-01 GLY A:231 A:238 67.0 0.893 S 130.0 -152.6 67.0 0.893 0.0 HOH
 3.232
 C
 O
2wy8 1 P01024 99.35 0.0 X-RAY
 2010-12-01 GLY A:231 A:238 64.0 0.853 S 123.2 -164.3 64.0 0.853 0.0 HOH
 3.125
 C
 O
3oed 1 P01024 99.35 0.0 X-RAY
 2011-05-11 GLY A:231 A:231 39.0 0.52 S -61.6 -106.9 39.0 0.52 0.0
GLY C:231 B:231 54.0 0.72 S -167.5 -156.6 NA NA NA
3oxu 1 P01024 99.68 0.0 X-RAY
 2011-02-16 GLY A:238 A:231 65.0 0.867 S 124.4 -157.3 NA NA NA
GLY B:238 B:231 60.0 0.8 S 137.8 -165.8 60.0 0.8 0.0 HOH
 2.810
 O
 O
GLY C:238 C:231 63.0 0.84 S 140.0 -157.3 NA NA NA
3rj3 1 P01024 99.68 0.0 X-RAY
 2012-03-14 GLY A:238 A:231 64.0 0.853 S 129.4 -153.0 64.0 0.853 0.0 HOH
 3.178
 C
 O
GLY B:238 B:231 54.0 0.72 S 132.8 -173.1 NA NA NA
GLY C:238 C:231 63.0 0.84 S 154.3 -150.8 NA NA NA
4ont 2 P01024 99.68 0.0 X-RAY
 2014-11-26 GLY B:238 A:231 65.0 0.867 S 130.3 -153.5 NA NA NA
GLY D:238 B:231 61.0 0.813 S 147.4 -168.7 61.0 0.813 0.0 HOH
 2.898
 O
 O
GLY F:238 C:231 52.0 0.693 S 153.4 -176.1 NA NA NA
4zh1 1 P01024 99.68 0.0 X-RAY
 2016-01-13 GLY A:238 A:231 62.0 0.827 S 145.8 -150.9 62.0 0.827 0.0 HOH
 3.058
 C
 O
GLY B:238 B:231 51.0 0.68 S 154.1 -159.5 NA NA NA
GLY C:238 C:231 62.0 0.827 S 148.6 -156.0 NA NA NA
1ghq 1 P01024 99.02 0.0 X-RAY
 2001-06-13 GLY A:231 A:231 63.0 0.84 S 77.8 96.0 63.0 0.84 0.0 HOH
 4.728
 N
 O
4m76 1 P01024 99.66 0.0 X-RAY
 2013-10-02 GLY A:234 A:1224 42.0 0.56 S -116.8 -179.7 42.0 0.56 0.0 HOH
 9.506
 N
 O
5nbq 1 P01024 99.66 0.0 X-RAY
 2017-12-06 GLY A:231 A:1224 64.0 0.853 S 149.2 -149.4 64.0 0.853 0.0
GLY B:231 B:1224 63.0 0.84 S 147.9 -149.6 NA NA NA
GLY C:231 C:1224 63.0 0.84 S 149.4 -154.7 NA NA NA
2gox 1 P01024 98.98 0.0 X-RAY
 2007-03-20 GLY A:234 A:1224 46.0 0.613 S 157.2 -161.1 46.0 0.613 0.0 HOH
 2.581
 O
 O
GLY C:234 C:1224 56.0 0.747 S 143.8 -169.0 NA NA NA
2noj 1 P01024 98.98 0.0 X-RAY
 2007-08-14 GLY A:234 A:1224 56.0 0.747 S -149.5 -136.0 56.0 0.747 0.0 HOH
 5.163
 O
 O
GLY C:234 NA:NA DO NA DO DO DO NA NA NA
GLY E:234 E:1224 65.0 0.867 S 119.9 -169.3 NA NA NA
GLY G:234 G:1224 62.0 0.827 S 159.6 -141.7 NA NA NA
3d5r 1 P01024 98.98 0.0 X-RAY
 2008-09-09 GLY A:234 A:235 46.0 0.613 S 173.6 -155.0 46.0 0.613 0.0 HOH
 5.309
 CA
 O
GLY C:234 B:235 51.0 0.68 S 163.6 -155.9 NA NA NA
3d5s 1 P01024 98.98 0.0 X-RAY
 2008-09-16 GLY A:234 A:235 44.0 0.587 S 164.6 -160.9 44.0 0.587 0.0 HOH
 9.556
 C
 O
GLY C:234 B:235 46.0 0.613 S 165.0 -158.8 NA NA NA
1c3d 1 P01024 99.32 0.0 X-RAY
 1998-10-07 GLY A:231 A:231 57.0 0.76 S -166.8 -142.5 57.0 0.76 0.0 HOH
 2.633
 O
 O
2xqw 1 P01024 99.32 0.0 X-RAY
 2011-02-02 GLY A:231 A:231 63.0 0.84 S 129.3 -161.8 63.0 0.84 0.0 HOH
 3.285
 C
 O
GLY B:231 B:231 67.0 0.893 S 131.5 -162.0 67.0 0.893 0.0 HOH
 3.260
 C
 O
1qqf 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 GLY A:215 A:1224 79.0 1.0 T 64.1 32.6 25.0 0.333 0.667 A:P01026:0.72
 HOH
 2.774
 O
 O
1qsj 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 GLY A:215 A:1224 81.0 1.0 T 61.7 26.1 27.0 0.36 0.64 B:P01026:0.72
 HOH
 2.636
 O
 O
GLY B:215 B:1224 80.0 1.0 T 64.4 23.6 26.0 0.347 0.653 A:P01026:0.72
 HOH
 3.439
 N
 O
GLY C:215 C:1224 80.0 1.0 T 63.3 26.5 NA NA NA
GLY D:215 D:1224 80.0 1.0 T 63.5 27.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 GLY A:1224 A:1224 82.0 1.0 T 74.4 21.2