Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6690659 . A C CCDS32883.1:NM_000064.2:c.3470aTt>aGt_NP_000055.2:p.1157I>S Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 ILE B:486 B:1157 64.0 0.366 T -85.5 -45.1 64.0 0.366 0.0
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 ILE B:485 B:1135 65.0 0.371 T -113.2 -43.7 65.0 0.371 0.0
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 ILE B:409 B:1135 102.0 0.583 T -75.9 -69.6 102.0 0.583 0.0
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 ILE B:409 B:1135 49.0 0.28 H -103.6 -36.5 8.0 0.046 0.234 C:P08603:0.234
 HOH
 4.720
 CD1
 O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 ILE B:409 B:1135 54.0 0.309 G -76.0 -32.4 54.0 0.309 0.0
ILE D:409 D:1135 54.0 0.309 G -76.4 -32.5 NA NA NA
ILE F:409 F:1135 54.0 0.309 G -76.0 -32.4 NA NA NA
ILE H:409 H:1135 54.0 0.309 T -76.4 -33.3 54.0 0.309 0.0
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 ILE B:409 B:1135 102.0 0.583 T -99.6 -60.6 102.0 0.583 0.0
ILE D:409 D:1135 59.0 0.337 T -69.8 -31.2 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 ILE B:409 B:1135 74.0 0.423 T -44.6 -49.6 74.0 0.423 0.0
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 ILE B:409 B:1157 64.0 0.366 T -92.1 -40.5 15.0 0.086 0.28 C:P08603:0.28
ILE G:409 F:1157 55.0 0.314 T -92.1 -41.2 14.0 0.08 0.234 H:P08603:0.234
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 ILE B:409 B:1157 61.0 0.349 T -93.5 -42.0 10.0 0.057 0.292 C:P08603:0.291
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 ILE F:409 B:1135 52.0 0.297 H -78.8 -42.6 52.0 0.297 0.0
ILE H:409 H:1135 57.0 0.326 T -77.5 -42.3 57.0 0.326 0.0
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 ILE H:409 B:1135 60.0 0.343 H -78.7 -41.1 60.0 0.343 0.0
ILE J:409 H:1135 52.0 0.297 H -78.7 -41.7 52.0 0.297 0.0
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 ILE B:409 B:1135 50.0 0.286 H -79.0 -36.6 50.0 0.286 0.0 HOH
 4.504
 CD1
 O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 ILE B:409 B:1135 53.0 0.303 G -78.4 -28.4 53.0 0.303 0.0
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 ILE B:409 B:1135 58.0 0.331 T -96.2 -51.4 58.0 0.331 0.0
ILE D:409 D:1135 59.0 0.337 T -96.5 -51.2 NA NA NA
ILE F:409 F:1135 59.0 0.337 T -96.2 -51.6 NA NA NA
ILE H:409 H:1135 57.0 0.326 T -96.4 -51.3 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ILE B:409 B:1157 66.0 0.377 T -92.6 -41.5 66.0 0.377 0.0
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ILE B:409 B:1157 43.0 0.246 T -69.1 -37.1 1.0 0.006 0.24 C:P15529:0.24
 HOH
 3.282
 N
 O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ILE B:409 B:1157 55.0 0.314 H -80.7 -42.4 NA NA NA
ILE E:409 E:1157 59.0 0.337 H -80.8 -43.4 59.0 0.337 0.0
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ILE B:409 B:1157 49.0 0.28 T -80.2 -29.6 49.0 0.28 0.0
ILE D:409 D:1157 32.0 0.183 G -79.2 -28.7 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ILE B:409 B:1157 45.0 0.257 H -86.2 -28.6 8.0 0.046 0.211 C:Q76U65:0.211
 GOL
CL
 9.823
8.825
 N
O
 O3
CL
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 ILE B:409 B:1157 60.0 0.343 T -106.2 -21.3 60.0 0.343 0.0
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 ILE B:409 B:1157 58.0 0.331 T -106.2 -21.2 58.0 0.331 0.0
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 ILE B:406 B:1135 55.0 0.314 T -102.7 -46.5 55.0 0.314 0.0
ILE D:406 D:1135 55.0 0.314 T -102.3 -47.1 NA NA NA
6rmt 1 P01024 99.68 0.0 X-RAY
 2020-11-18 ILE A:164 A:164 59.0 0.337 H -74.7 -34.4 59.0 0.337 0.0 HOH
 2.246
 H
 O
ILE B:164 B:164 55.0 0.314 H -74.9 -40.1 55.0 0.314 0.0 HOH
 2.325
 H
 O
6rmu 1 P01024 99.68 0.0 X-RAY
 2020-11-18 ILE A:164 A:164 45.0 0.257 H -81.7 -22.6 4.0 0.023 0.234 B:Q931F4:0.234
 HOH
 2.963
 O
 O
ILE C:164 B:164 46.0 0.263 H -85.1 -22.7 12.0 0.069 0.194 D:Q931F4:0.194
 HOH
 2.729
 O
 O
2wy7 1 P01024 99.35 0.0 X-RAY
 2010-12-01 ILE A:164 A:171 45.0 0.257 H -81.8 -38.7 45.0 0.257 0.0 HOH
 2.790
 O
 O
2wy8 1 P01024 99.35 0.0 X-RAY
 2010-12-01 ILE A:164 A:171 46.0 0.263 H -81.8 -38.3 11.0 0.063 0.2 B:C8LN82:0.2
 HOH
 2.761
 O
 O
3oed 1 P01024 99.35 0.0 X-RAY
 2011-05-11 ILE A:164 A:164 59.0 0.337 H -91.6 -46.7 6.0 0.034 0.303 B:P20023:0.303
ILE C:164 B:164 57.0 0.326 H -79.3 -32.1 NA NA NA
3oxu 1 P01024 99.68 0.0 X-RAY
 2011-02-16 ILE A:171 A:164 48.0 0.274 H -74.6 -37.0 NA NA NA
ILE B:171 B:164 57.0 0.326 H -56.8 -45.6 57.0 0.326 0.0 GOL
HOH
 7.238
2.424
 CD1
O
 O2
O
ILE C:171 C:164 54.0 0.309 H -74.6 -37.5 NA NA NA
3rj3 1 P01024 99.68 0.0 X-RAY
 2012-03-14 ILE A:171 A:164 45.0 0.257 H -82.3 -39.1 45.0 0.257 0.0 HOH
 5.195
 CD1
 O
ILE B:171 B:164 63.0 0.36 H -73.5 -33.6 NA NA NA
ILE C:171 C:164 56.0 0.32 H -85.1 -36.6 NA NA NA
4ont 2 P01024 99.68 0.0 X-RAY
 2014-11-26 ILE B:171 A:164 52.0 0.297 H -67.8 -34.3 NA NA NA
ILE D:171 B:164 53.0 0.303 H -63.5 -39.7 53.0 0.303 0.0 GOL
HOH
 8.054
2.548
 CD1
O
 C1
O
ILE F:171 C:164 65.0 0.371 H -69.6 -33.5 NA NA NA
4zh1 1 P01024 99.68 0.0 X-RAY
 2016-01-13 ILE A:171 A:164 53.0 0.303 H -74.0 -37.9 53.0 0.303 0.0 HOH
 2.989
 CD1
 O
ILE B:171 B:164 62.0 0.354 H -66.6 -34.6 NA NA NA
ILE C:171 C:164 63.0 0.36 H -71.6 -36.6 NA NA NA
1ghq 1 P01024 99.02 0.0 X-RAY
 2001-06-13 ILE A:164 A:164 53.0 0.303 H -67.2 -36.2 53.0 0.303 0.0 HOH
 2.777
 O
 O
4m76 1 P01024 99.66 0.0 X-RAY
 2013-10-02 ILE A:167 A:1157 79.0 0.451 T -80.3 -16.8 79.0 0.451 0.0 HOH
 9.361
 N
 O
5nbq 1 P01024 99.66 0.0 X-RAY
 2017-12-06 ILE A:164 A:1157 54.0 0.309 H -67.9 -35.2 54.0 0.309 0.0
ILE B:164 B:1157 50.0 0.286 H -69.2 -36.8 NA NA NA
ILE C:164 C:1157 48.0 0.274 H -62.9 -43.4 NA NA NA
2gox 1 P01024 98.98 0.0 X-RAY
 2007-03-20 ILE A:167 A:1157 47.0 0.269 H -87.4 -28.8 15.0 0.086 0.183 B:P68799:0.183
 HOH
 3.231
 CG1
 O
ILE C:167 C:1157 48.0 0.274 H -85.4 -33.0 NA NA NA
2noj 1 P01024 98.98 0.0 X-RAY
 2007-08-14 ILE A:167 A:1157 56.0 0.32 H -64.5 -59.5 6.0 0.034 0.286 B:Q99UV2:0.286
 HOH
 8.934
 O
 O
ILE C:167 C:1157 68.0 0.389 H -64.6 -56.5 NA NA NA
ILE E:167 E:1157 60.0 0.343 H -109.3 -49.4 NA NA NA
ILE G:167 G:1157 59.0 0.337 H -96.6 -36.8 NA NA NA
3d5r 1 P01024 98.98 0.0 X-RAY
 2008-09-09 ILE A:167 A:168 58.0 0.331 H -72.7 -36.7 14.0 0.08 0.251 B:A6QG59:0.251
 HOH
 6.025
 CG2
 O
ILE C:167 B:168 48.0 0.274 H -72.6 -33.4 NA NA NA
3d5s 1 P01024 98.98 0.0 X-RAY
 2008-09-16 ILE A:167 A:168 53.0 0.303 H -73.1 -33.6 14.0 0.08 0.223 B:A6QG59:0.223
 HOH
 5.821
 CG1
 O
ILE C:167 B:168 54.0 0.309 H -71.0 -36.3 NA NA NA
1c3d 1 P01024 99.32 0.0 X-RAY
 1998-10-07 ILE A:164 A:164 59.0 0.337 H -65.2 -38.0 59.0 0.337 0.0 GOL
HOH
 9.783
4.611
 CD1
CD1
 C2
O
2xqw 1 P01024 99.32 0.0 X-RAY
 2011-02-02 ILE A:164 A:164 48.0 0.274 H -82.5 -33.3 48.0 0.274 0.0 HOH
 3.549
 O
 O
ILE B:164 B:164 62.0 0.354 H -72.1 -26.4 62.0 0.354 0.0 HOH
 5.484
 CD1
 O
1qqf 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 ILE A:148 A:1157 54.0 0.309 H -88.0 -37.6 54.0 0.309 0.0 HOH
 2.998
 N
 O
1qsj 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 ILE A:148 A:1157 58.0 0.331 H -99.3 -36.1 58.0 0.331 0.0 HOH
 2.609
 O
 O
ILE B:148 B:1157 57.0 0.326 H -99.1 -36.5 57.0 0.326 0.0 HOH
 2.946
 N
 O
ILE C:148 C:1157 59.0 0.337 H -98.7 -37.3 NA NA NA
ILE D:148 D:1157 57.0 0.326 H -100.3 -37.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 ILE A:1157 A:1157 51.0 0.291 H -87.0 -35.0