Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6690728 . C A CCDS32883.1:NM_000064.2:c.3401cGg>cTg_NP_000055.2:p.1134R>L Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 ARG B:463 B:1134 237.0 1.0 S -61.7 -32.7 237.0 1.0 0.0
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 ARG B:462 NA:NA DO NA DO DO DO NA NA NA
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 ARG B:386 B:1112 131.0 0.582 G -65.8 -26.8 131.0 0.582 0.0
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 ARG B:386 B:1112 101.0 0.449 G -72.6 -26.5 101.0 0.449 0.0 GOL
HOH
 6.390
3.056
 N
O
 O1
O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 ARG B:386 B:1112 114.0 0.507 G -70.6 -27.1 114.0 0.507 0.0
ARG D:386 D:1112 114.0 0.507 G -70.6 -27.2 NA NA NA
ARG F:386 F:1112 114.0 0.507 G -70.6 -27.1 NA NA NA
ARG H:386 H:1112 113.0 0.502 G -72.3 -26.6 113.0 0.502 0.0
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 ARG B:386 B:1112 111.0 0.493 G -55.9 -35.8 111.0 0.493 0.0
ARG D:386 D:1112 116.0 0.516 G -65.4 -16.1 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 ARG B:386 B:1112 92.0 0.409 -40.9 -28.4 92.0 0.409 0.0
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 ARG B:386 B:1134 74.0 0.329 T -68.6 132.2 74.0 0.329 0.0
ARG G:386 F:1134 84.0 0.373 T -68.5 134.2 84.0 0.373 0.0
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 ARG B:386 B:1134 93.0 0.413 G -67.7 -38.5 93.0 0.413 0.0
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 ARG F:386 B:1112 119.0 0.529 G -66.0 -29.7 119.0 0.529 0.0
ARG H:386 H:1112 84.0 0.373 G -62.8 -33.7 84.0 0.373 0.0
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 ARG H:386 B:1112 118.0 0.524 G -68.7 -27.1 118.0 0.524 0.0
ARG J:386 H:1112 112.0 0.498 G -69.9 -27.0 112.0 0.498 0.0
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 ARG B:386 B:1112 74.0 0.329 T -70.9 138.5 74.0 0.329 0.0 PEG
HOH
 4.269
2.890
 CA
O
 O4
O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 ARG B:386 B:1112 100.0 0.444 S -53.1 -41.3 100.0 0.444 0.0
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 ARG B:386 B:1112 115.0 0.511 S -60.5 -58.2 115.0 0.511 0.0
ARG D:386 D:1112 117.0 0.52 S -60.2 -58.3 NA NA NA
ARG F:386 F:1112 116.0 0.516 S -60.7 -57.9 NA NA NA
ARG H:386 H:1112 118.0 0.524 S -60.4 -58.3 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ARG B:386 B:1134 102.0 0.453 G -66.1 -37.4 102.0 0.453 0.0
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ARG B:386 B:1134 79.0 0.351 T -63.0 132.4 79.0 0.351 0.0 EDO
HOH
 6.271
2.625
 CA
O
 C2
O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ARG B:386 B:1134 109.0 0.484 -74.7 -167.4 NA NA NA
ARG E:386 E:1134 113.0 0.502 S -76.8 161.7 113.0 0.502 0.0
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ARG B:386 B:1134 75.0 0.333 T -54.1 -35.0 75.0 0.333 0.0
ARG D:386 D:1134 105.0 0.467 T -48.9 -52.4 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ARG B:386 B:1134 121.0 0.538 G -62.4 -31.5 121.0 0.538 0.0 IOD
HOH
 6.741
2.788
 N
O
 I
O
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 ARG B:386 B:1134 75.0 0.333 T -77.0 140.4 75.0 0.333 0.0
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 ARG B:386 B:1134 73.0 0.324 T -77.0 140.3 73.0 0.324 0.0
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 ARG B:383 B:1112 118.0 0.524 S -63.0 -32.7 118.0 0.524 0.0
ARG D:383 D:1112 116.0 0.516 S -64.0 -32.8 NA NA NA
6rmt 1 P01024 99.68 0.0 X-RAY
 2020-11-18 ARG A:141 A:141 87.0 0.387 T -69.0 126.0 87.0 0.387 0.0 HOH
 2.074
 HH12
 O
ARG B:141 B:141 105.0 0.467 G -60.1 -29.5 105.0 0.467 0.0 HOH
 2.212
 HH12
 O
6rmu 1 P01024 99.68 0.0 X-RAY
 2020-11-18 ARG A:141 A:141 68.0 0.302 T -69.7 142.4 68.0 0.302 0.0 HOH
 2.261
 HE
 O
ARG C:141 B:141 84.0 0.373 T -55.6 131.3 84.0 0.373 0.0 EDO
HOH
 4.719
2.468
 HA
HE
 H11
O
2wy7 1 P01024 99.35 0.0 X-RAY
 2010-12-01 ARG A:141 A:148 84.0 0.373 T -65.4 129.1 60.0 0.267 0.106 B:C8LN82:0.107
 GOL
HOH
 5.682
2.755
 CA
O
 O1
O
2wy8 1 P01024 99.35 0.0 X-RAY
 2010-12-01 ARG A:141 A:148 82.0 0.364 T -64.6 128.3 82.0 0.364 0.0 GOL
HOH
 5.710
2.771
 CA
O
 O1
O
3oed 1 P01024 99.35 0.0 X-RAY
 2011-05-11 ARG A:141 A:141 109.0 0.484 G -63.6 -33.7 109.0 0.484 0.0
ARG C:141 B:141 112.0 0.498 G -52.3 -30.5 NA NA NA
3oxu 1 P01024 99.68 0.0 X-RAY
 2011-02-16 ARG A:148 A:141 80.0 0.356 T -65.8 131.4 NA NA NA
ARG B:148 B:141 108.0 0.48 G -60.5 -28.5 108.0 0.48 0.0 GOL
HOH
 5.646
2.785
 CA
NH1
 C1
O
ARG C:148 C:141 110.0 0.489 G -65.5 -40.4 NA NA NA
3rj3 1 P01024 99.68 0.0 X-RAY
 2012-03-14 ARG A:148 A:141 85.0 0.378 T -47.3 -74.3 81.0 0.36 0.018 D:Q03591:0.018
 GOL
HOH
 5.350
2.781
 O
O
 O1
O
ARG B:148 B:141 109.0 0.484 G -55.5 -27.8 NA NA NA
ARG C:148 C:141 78.0 0.347 T -55.5 -61.2 NA NA NA
4ont 2 P01024 99.68 0.0 X-RAY
 2014-11-26 ARG B:148 A:141 83.0 0.369 T -68.7 135.4 NA NA NA
ARG D:148 B:141 123.0 0.547 G -57.9 -16.3 123.0 0.547 0.0 GOL
HOH
 6.007
3.741
 CA
CB
 O1
O
ARG F:148 C:141 111.0 0.493 -55.9 -39.9 NA NA NA
4zh1 1 P01024 99.68 0.0 X-RAY
 2016-01-13 ARG A:148 A:141 82.0 0.364 T -64.5 129.5 82.0 0.364 0.0 GOL
HOH
 6.185
2.652
 CA
NH1
 O1
O
ARG B:148 B:141 126.0 0.56 T -62.2 -39.0 NA NA NA
ARG C:148 C:141 108.0 0.48 G -61.5 -32.9 NA NA NA
1ghq 1 P01024 99.02 0.0 X-RAY
 2001-06-13 ARG A:141 A:141 119.0 0.529 G -62.9 -34.7 119.0 0.529 0.0 HOH
 2.708
 NH1
 O
4m76 1 P01024 99.66 0.0 X-RAY
 2013-10-02 ARG A:144 A:1134 74.0 0.329 T -72.9 123.4 74.0 0.329 0.0 HOH
 7.017
 N
 O
5nbq 1 P01024 99.66 0.0 X-RAY
 2017-12-06 ARG A:141 A:1134 109.0 0.484 G -58.7 -36.7 109.0 0.484 0.0
ARG B:141 B:1134 102.0 0.453 G -58.5 -38.4 NA NA NA
ARG C:141 C:1134 104.0 0.462 G -57.9 -37.6 NA NA NA
2gox 1 P01024 98.98 0.0 X-RAY
 2007-03-20 ARG A:144 A:1134 114.0 0.507 G -61.0 -33.2 114.0 0.507 0.0 HOH
 2.318
 O
 O
ARG C:144 C:1134 104.0 0.462 G -59.8 -34.0 NA NA NA
2noj 1 P01024 98.98 0.0 X-RAY
 2007-08-14 ARG A:144 A:1134 117.0 0.52 G -72.8 -30.1 117.0 0.52 0.0 HOH
 2.839
 NH2
 O
ARG C:144 C:1134 37.0 NA G -84.6 -21.7 NA NA NA
ARG E:144 E:1134 142.0 0.631 G -56.0 -19.9 NA NA NA
ARG G:144 G:1134 117.0 0.52 G -69.0 -16.1 NA NA NA
3d5r 1 P01024 98.98 0.0 X-RAY
 2008-09-09 ARG A:144 A:145 105.0 0.467 G -73.3 -33.0 105.0 0.467 0.0 HOH
 2.764
 NH1
 O
ARG C:144 B:145 104.0 0.462 G -72.6 -28.1 NA NA NA
3d5s 1 P01024 98.98 0.0 X-RAY
 2008-09-16 ARG A:144 A:145 113.0 0.502 G -68.1 -28.2 113.0 0.502 0.0 HOH
 3.812
 CD
 O
ARG C:144 B:145 112.0 0.498 G -70.9 -25.0 NA NA NA
1c3d 1 P01024 99.32 0.0 X-RAY
 1998-10-07 ARG A:141 A:141 106.0 0.471 G -60.9 -30.8 106.0 0.471 0.0 GOL
HOH
 6.061
3.292
 CA
NH1
 O3
O
2xqw 1 P01024 99.32 0.0 X-RAY
 2011-02-02 ARG A:141 A:141 108.0 0.48 S -54.3 -45.9 108.0 0.48 0.0 HOH
 2.699
 NH1
 O
ARG B:141 B:141 100.0 0.444 G -69.0 -34.6 100.0 0.444 0.0 HOH
 2.531
 O
 O
1qqf 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 ARG A:125 A:1134 112.0 0.498 G -64.5 -32.2 68.0 0.302 0.196 A:P01026:0.196
 HOH
 2.997
 NH1
 O
1qsj 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 ARG A:125 A:1134 113.0 0.502 G -58.3 -38.8 81.0 0.36 0.142 B:P01026:0.142
 HOH
 2.714
 O
 O
ARG B:125 B:1134 114.0 0.507 G -61.5 -37.9 79.0 0.351 0.156 A:P01026:0.156
 HOH
 2.447
 NH1
 O
ARG C:125 C:1134 115.0 0.511 G -60.1 -38.0 NA NA NA
ARG D:125 D:1134 116.0 0.516 G -60.3 -37.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 ARG A:1134 A:1134 94.0 0.418 G -54.8 -27.3