Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6693022 . G A CCDS32883.1:NM_000064.2:c.3303tgC>tgT_NP_000055.2:p.1101C>C Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 CYS B:430 B:1101 9.0 0.067 H -65.4 -38.8 9.0 0.067 0.0
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 CYS B:429 B:1079 4.0 0.03 H -79.3 -24.0 4.0 0.03 0.0
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 CYS B:353 B:1079 8.0 0.059 T -99.3 20.8 8.0 0.059 0.0
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 CYS B:353 B:1079 4.0 0.03 H -66.2 -34.3 4.0 0.03 0.0 HOH
 7.796
 O
 O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 CYS B:353 B:1079 6.0 0.044 H -69.0 -25.8 6.0 0.044 0.0
CYS D:353 D:1079 6.0 0.044 H -68.9 -26.3 NA NA NA
CYS F:353 F:1079 5.0 0.037 H -68.9 -25.9 NA NA NA
CYS H:353 H:1079 6.0 0.044 H -73.9 -22.9 6.0 0.044 0.0
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 CYS B:353 B:1079 9.0 0.067 H -67.3 -23.6 9.0 0.067 0.0
CYS D:353 D:1079 5.0 0.037 H -86.9 -28.1 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 CYS B:353 B:1079 12.0 0.089 T -91.5 20.5 12.0 0.089 0.0
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 CYS B:353 B:1101 4.0 0.03 H -65.9 -32.3 0.0 0.0 0.03 C:P08603:0.03
CYS G:353 F:1101 5.0 0.037 H -65.7 -32.0 1.0 0.007 0.03 H:P08603:0.03
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 CYS B:353 B:1101 2.0 0.015 H -66.0 -32.0 2.0 0.015 0.0
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 CYS F:353 B:1079 6.0 0.044 H -72.1 -24.6 6.0 0.044 0.0
CYS H:353 H:1079 6.0 0.044 H -71.9 -24.8 6.0 0.044 0.0
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 CYS H:353 B:1079 5.0 0.037 H -73.1 -18.6 5.0 0.037 0.0
CYS J:353 H:1079 5.0 0.037 H -73.7 -19.3 5.0 0.037 0.0
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 CYS B:353 B:1079 4.0 0.03 H -77.2 -24.4 4.0 0.03 0.0 HOH
 6.307
 N
 O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 CYS B:353 B:1079 4.0 0.03 H -76.1 -25.1 4.0 0.03 0.0
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 CYS B:353 B:1079 2.0 0.015 H -71.3 -23.7 2.0 0.015 0.0
CYS D:353 D:1079 2.0 0.015 H -72.0 -23.5 NA NA NA
CYS F:353 F:1079 2.0 0.015 H -72.0 -23.8 NA NA NA
CYS H:353 H:1079 2.0 0.015 H -71.5 -23.5 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 CYS B:353 B:1101 5.0 0.037 H -66.9 -32.9 5.0 0.037 0.0
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 CYS B:353 B:1101 3.0 0.022 H -75.2 -27.2 3.0 0.022 0.0 EDO
HOH
 7.772
4.931
 O
C
 C2
O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 CYS B:353 B:1101 5.0 0.037 H -61.7 -26.4 NA NA NA
CYS E:353 E:1101 2.0 0.015 H -61.1 -25.4 2.0 0.015 0.0
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 CYS B:353 B:1101 3.0 0.022 H -74.9 -26.1 3.0 0.022 0.0
CYS D:353 D:1101 1.0 0.007 H -76.2 -25.9 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 CYS B:353 B:1101 1.0 0.007 H -62.7 -28.8 1.0 0.007 0.0 IOD
CL
 7.490
3.858
 O
C
 I
CL
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 CYS B:353 B:1101 4.0 0.03 H -73.9 -25.9 4.0 0.03 0.0
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 CYS B:353 B:1101 5.0 0.037 H -73.9 -25.9 5.0 0.037 0.0
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 CYS B:350 B:1079 4.0 0.03 H -79.2 -22.6 4.0 0.03 0.0
CYS D:350 D:1079 4.0 0.03 H -80.0 -21.9 NA NA NA
6rmt 1 P01024 99.68 0.0 X-RAY
 2020-11-18 CYS A:108 A:108 4.0 0.03 H -77.2 -21.9 4.0 0.03 0.0 HOH
 2.699
 HB2
 O
CYS B:108 B:108 4.0 0.03 H -79.3 -28.7 4.0 0.03 0.0 HOH
 2.966
 HB2
 O
6rmu 1 P01024 99.68 0.0 X-RAY
 2020-11-18 CYS A:108 A:108 4.0 0.03 H -69.5 -29.2 4.0 0.03 0.0 HOH
 5.260
 O
 O
CYS C:108 B:108 5.0 0.037 H -77.1 -31.4 5.0 0.037 0.0 HOH
 4.968
 O
 O
2wy7 1 P01024 99.35 0.0 X-RAY
 2010-12-01 CYS A:108 A:115 2.0 0.015 H -76.6 -26.8 2.0 0.015 0.0 HOH
 3.639
 CB
 O
2wy8 1 P01024 99.35 0.0 X-RAY
 2010-12-01 CYS A:108 A:115 2.0 0.015 H -76.5 -26.4 2.0 0.015 0.0 HOH
 3.691
 CB
 O
3oed 1 P01024 99.35 0.0 X-RAY
 2011-05-11 CYS A:108 A:108 2.0 0.015 H -65.9 -35.8 2.0 0.015 0.0
CYS C:108 B:108 4.0 0.03 H -69.6 -29.1 NA NA NA
3oxu 1 P01024 99.68 0.0 X-RAY
 2011-02-16 CYS A:115 A:108 8.0 0.059 H -71.0 -28.5 NA NA NA
CYS B:115 B:108 4.0 0.03 H -79.2 -24.6 0.0 0.0 0.03 F:Q14006:0.03
 HOH
 4.775
 O
 O
CYS C:115 C:108 4.0 0.03 H -72.4 -29.3 NA NA NA
3rj3 1 P01024 99.68 0.0 X-RAY
 2012-03-14 CYS A:115 A:108 7.0 0.052 H -73.6 -22.7 7.0 0.052 0.0 HOH
 5.101
 O
 O
CYS B:115 B:108 3.0 0.022 H -75.4 -28.5 NA NA NA
CYS C:115 C:108 5.0 0.037 H -76.4 -22.4 NA NA NA
4ont 2 P01024 99.68 0.0 X-RAY
 2014-11-26 CYS B:115 A:108 6.0 0.044 H -73.2 -25.5 NA NA NA
CYS D:115 B:108 5.0 0.037 H -76.2 -28.1 0.0 0.0 0.037 A:P08603:0.037
 HOH
 4.996
 O
 O
CYS F:115 C:108 5.0 0.037 H -75.7 -25.9 NA NA NA
4zh1 1 P01024 99.68 0.0 X-RAY
 2016-01-13 CYS A:115 A:108 5.0 0.037 H -73.1 -26.9 0.0 0.0 0.037 E:P08603:0.037
 HOH
 5.093
 O
 O
CYS B:115 B:108 5.0 0.037 H -74.1 -25.7 NA NA NA
CYS C:115 C:108 5.0 0.037 H -71.4 -28.0 NA NA NA
1ghq 1 P01024 99.02 0.0 X-RAY
 2001-06-13 CYS A:108 A:108 3.0 0.022 H -71.9 -25.3 3.0 0.022 0.0 ZN
HOH
 9.467
3.802
 O
CB
 ZN
O
4m76 1 P01024 99.66 0.0 X-RAY
 2013-10-02 CYS A:111 A:1101 1.0 0.007 H -72.8 -30.3 1.0 0.007 0.0 HOH
 9.733
 N
 O
5nbq 1 P01024 99.66 0.0 X-RAY
 2017-12-06 CYS A:108 A:1101 4.0 0.03 H -68.4 -24.0 0.0 0.0 0.03 D:P08603:0.03
CYS B:108 B:1101 4.0 0.03 H -69.7 -23.1 NA NA NA
CYS C:108 C:1101 3.0 0.022 H -63.2 -37.7 NA NA NA
2gox 1 P01024 98.98 0.0 X-RAY
 2007-03-20 CYS A:111 A:1101 0.0 0.0 H -66.8 -31.2 0.0 0.0 0.0 HOH
 4.564
 C
 O
CYS C:111 C:1101 1.0 0.007 H -63.6 -32.5 NA NA NA
2noj 1 P01024 98.98 0.0 X-RAY
 2007-08-14 CYS A:111 A:1101 8.0 0.059 H -72.6 -31.9 8.0 0.059 0.0 HOH
 6.719
 N
 O
CYS C:111 C:1101 11.0 0.081 H -65.9 -31.4 NA NA NA
CYS E:111 E:1101 5.0 0.037 H -85.0 -23.9 NA NA NA
CYS G:111 G:1101 17.0 0.126 H -67.9 -22.0 NA NA NA
3d5r 1 P01024 98.98 0.0 X-RAY
 2008-09-09 CYS A:111 A:112 0.0 0.0 H -73.9 -22.5 0.0 0.0 0.0 HOH
 6.152
 N
 O
CYS C:111 B:112 0.0 0.0 H -73.5 -25.0 NA NA NA
3d5s 1 P01024 98.98 0.0 X-RAY
 2008-09-16 CYS A:111 A:112 0.0 0.0 H -74.9 -20.7 0.0 0.0 0.0 HOH
 5.212
 O
 O
CYS C:111 B:112 0.0 0.0 H -77.1 -20.9 NA NA NA
1c3d 1 P01024 99.32 0.0 X-RAY
 1998-10-07 CYS A:108 A:108 3.0 0.022 H -68.4 -24.4 3.0 0.022 0.0 HOH
 6.202
 C
 O
2xqw 1 P01024 99.32 0.0 X-RAY
 2011-02-02 CYS A:108 A:108 1.0 0.007 H -71.2 -29.1 1.0 0.007 0.0 HOH
 5.167
 O
 O
CYS B:108 B:108 3.0 0.022 H -72.7 -29.7 3.0 0.022 0.0 HOH
 6.187
 N
 O
1qqf 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 CYS A:92 A:1101 0.0 0.0 H -75.5 -22.9 0.0 0.0 0.0 HOH
 3.769
 CB
 O
1qsj 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 CYS A:92 A:1101 4.0 0.03 H -74.7 -19.9 4.0 0.03 0.0 HOH
 5.619
 SG
 O
CYS B:92 B:1101 4.0 0.03 H -70.1 -24.5 4.0 0.03 0.0 HOH
 4.041
 C
 O
CYS C:92 C:1101 3.0 0.022 H -71.7 -22.6 NA NA NA
CYS D:92 D:1101 4.0 0.03 H -70.6 -23.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 CYS A:1101 A:1101 4.0 0.03 H -71.6 -22.2