Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6694511 . C A CCDS32883.1:NM_000064.2:c.3085Gat>Tat_NP_000055.2:p.1029D>Y Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 ASP B:358 B:1029 44.0 0.293 H -71.3 -42.3 44.0 0.293 0.0
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 ASP B:357 B:1007 47.0 0.313 H -70.8 -45.4 47.0 0.313 0.0
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 ASP B:281 B:1007 47.0 0.313 H -66.0 -49.5 27.0 0.18 0.133 A:P01024:0.133
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 ASP B:281 B:1007 51.0 0.34 H -66.0 -45.0 36.0 0.24 0.1 A:P01024:0.1
 HOH
 7.212
 OD1
 O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 ASP B:281 B:1007 51.0 0.34 H -72.6 -42.4 33.0 0.22 0.12 A:P01024:0.12
ASP D:281 D:1007 52.0 0.347 H -72.6 -42.4 NA NA NA
ASP F:281 F:1007 51.0 0.34 H -72.6 -42.5 NA NA NA
ASP H:281 H:1007 54.0 0.36 H -74.9 -39.4 43.0 0.287 0.073 G:P01024:0.073
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 ASP B:281 B:1007 49.0 0.327 H -66.1 -46.3 31.0 0.207 0.12 A:P01024:0.12
ASP D:281 D:1007 56.0 0.373 H -58.1 -52.6 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 ASP B:281 B:1007 43.0 0.287 H -77.3 -49.9 20.0 0.133 0.154 A:P01024:0.153
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 ASP B:281 B:1029 53.0 0.353 H -68.3 -42.2 33.0 0.22 0.133 A:P01024:0.133
ASP G:281 F:1029 56.0 0.373 H -68.2 -42.5 40.0 0.267 0.106 F:P01024:0.107
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 ASP B:281 B:1029 54.0 0.36 H -68.3 -42.6 35.0 0.233 0.127 A:P01024:0.127
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 ASP F:281 B:1007 46.0 0.307 H -66.0 -49.7 25.0 0.167 0.14 E:P01024:0.14
ASP H:281 H:1007 41.0 0.273 H -66.4 -49.5 20.0 0.133 0.14 G:P01024:0.14
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 ASP H:281 B:1007 44.0 0.293 H -68.8 -50.1 20.0 0.133 0.16 G:P01024:0.16
ASP J:281 H:1007 45.0 0.3 H -69.3 -49.8 24.0 0.16 0.14 I:P01024:0.14
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 ASP B:281 B:1007 44.0 0.293 H -58.4 -53.0 27.0 0.18 0.113 A:P01024:0.113
 HOH
 3.027
 OD2
 O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 ASP B:281 B:1007 36.0 0.24 H -72.6 -28.6 25.0 0.167 0.073 A:P01024:0.073
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 ASP B:281 B:1007 37.0 0.247 H -75.9 -30.1 6.0 0.04 0.207 A:P01024:0.207
ASP D:281 D:1007 37.0 0.247 H -75.2 -30.0 NA NA NA
ASP F:281 F:1007 38.0 0.253 H -75.4 -29.9 NA NA NA
ASP H:281 H:1007 36.0 0.24 H -75.7 -29.7 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ASP B:281 B:1029 50.0 0.333 H -68.5 -43.4 33.0 0.22 0.113 A:P01024:0.113
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ASP B:281 B:1029 53.0 0.353 H -62.2 -47.8 35.0 0.233 0.12 A:P01024:0.12
 EDO
EDO
HOH
 5.104
4.993
3.091
 OD2
O
O
 O1
O2
O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ASP B:281 B:1029 60.0 0.4 H -62.6 -47.5 NA NA NA
ASP E:281 E:1029 58.0 0.387 H -65.0 -45.3 36.0 0.24 0.147 D:P01024:0.147
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ASP B:281 B:1029 45.0 0.3 H -71.9 -28.0 29.0 0.193 0.107 A:P01024:0.107
ASP D:281 D:1029 21.0 0.14 H -72.0 -27.1 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ASP B:281 B:1029 43.0 0.287 H -61.6 -46.0 30.0 0.2 0.087 A:P01024:0.087
 IOD
HOH
 5.402
7.242
 O
OD1
 I
O
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 ASP B:281 B:1029 56.0 0.373 H -70.1 -37.5 30.0 0.2 0.173 A:P01024:0.173
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 ASP B:281 B:1029 53.0 0.353 H -70.1 -37.5 26.0 0.173 0.18 A:None:0.18
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 ASP B:278 B:1007 39.0 0.26 H -72.3 -29.8 27.0 0.18 0.08 A:P01024:0.08
ASP D:278 D:1007 39.0 0.26 H -72.3 -30.0 NA NA NA
6rmt 1 P01024 99.68 0.0 X-RAY
 2020-11-18 ASP A:36 A:36 47.0 0.313 H -59.2 -55.8 47.0 0.313 0.0 HOH
 2.993
 O
 O
ASP B:36 B:36 47.0 0.313 H -54.2 -59.2 47.0 0.313 0.0 CL
HOH
 7.137
2.722
 OD1
OD2
 CL
O
6rmu 1 P01024 99.68 0.0 X-RAY
 2020-11-18 ASP A:36 A:36 51.0 0.34 H -55.9 -42.3 7.0 0.047 0.293 B:Q931F4:0.293
 HOH
 2.495
 O
 O
ASP C:36 B:36 47.0 0.313 H -60.5 -46.6 6.0 0.04 0.273 D:Q931F4:0.273
 HOH
 3.079
 HB2
 O
2wy7 1 P01024 99.35 0.0 X-RAY
 2010-12-01 ASP A:36 A:43 42.0 0.28 H -59.7 -54.9 42.0 0.28 0.0 HOH
 2.649
 O
 O
2wy8 1 P01024 99.35 0.0 X-RAY
 2010-12-01 ASP A:36 A:43 43.0 0.287 H -60.3 -54.3 6.0 0.04 0.247 B:C8LN82:0.247
 HOH
 2.644
 O
 O
3oed 1 P01024 99.35 0.0 X-RAY
 2011-05-11 ASP A:36 A:36 42.0 0.28 H -53.7 -58.2 9.0 0.06 0.22 B:P20023:0.22
 HOH
 5.784
 O
 O
ASP C:36 B:36 40.0 0.267 H -64.8 -46.7 NA NA NA
3oxu 1 P01024 99.68 0.0 X-RAY
 2011-02-16 ASP A:43 A:36 46.0 0.307 H -55.0 -55.1 NA NA NA
ASP B:43 B:36 43.0 0.287 H -66.6 -49.4 43.0 0.287 0.0 HOH
 2.654
 O
 O
ASP C:43 C:36 44.0 0.293 H -69.6 -47.0 NA NA NA
3rj3 1 P01024 99.68 0.0 X-RAY
 2012-03-14 ASP A:43 A:36 47.0 0.313 H -54.5 -48.7 47.0 0.313 0.0 HOH
 4.274
 O
 O
ASP B:43 B:36 39.0 0.26 H -71.1 -45.0 NA NA NA
ASP C:43 C:36 33.0 0.22 T -103.3 -49.9 NA NA NA
4ont 2 P01024 99.68 0.0 X-RAY
 2014-11-26 ASP B:43 A:36 45.0 0.3 H -54.6 -50.3 NA NA NA
ASP D:43 B:36 44.0 0.293 H -71.5 -41.6 44.0 0.293 0.0 GOL
HOH
 3.556
2.745
 O
OD1
 C3
O
ASP F:43 C:36 41.0 0.273 H -54.2 -50.3 NA NA NA
4zh1 1 P01024 99.68 0.0 X-RAY
 2016-01-13 ASP A:43 A:36 47.0 0.313 H -55.8 -48.9 47.0 0.313 0.0 HOH
 2.752
 OD2
 O
ASP B:43 B:36 44.0 0.293 H -58.9 -43.6 NA NA NA
ASP C:43 C:36 44.0 0.293 H -57.8 -47.5 NA NA NA
1ghq 1 P01024 99.02 0.0 X-RAY
 2001-06-13 ASP A:36 A:36 45.0 0.3 H -60.7 -50.2 45.0 0.3 0.0 HOH
 2.906
 OD2
 O
4m76 1 P01024 99.66 0.0 X-RAY
 2013-10-02 ASP A:39 A:1029 47.0 0.313 H -67.8 -49.3 47.0 0.313 0.0 HOH
 9.653
 CB
 O
5nbq 1 P01024 99.66 0.0 X-RAY
 2017-12-06 ASP A:36 A:1029 72.0 0.48 H -54.7 -53.9 72.0 0.48 0.0
ASP B:36 B:1029 42.0 0.28 H -63.6 -54.4 NA NA NA
ASP C:36 C:1029 44.0 0.293 H -64.0 -53.6 NA NA NA
2gox 1 P01024 98.98 0.0 X-RAY
 2007-03-20 ASP A:39 A:1029 48.0 0.32 H -65.9 -46.2 8.0 0.053 0.267 B:P68799:0.267
 HOH
 3.642
 C
 O
ASP C:39 C:1029 44.0 0.293 H -64.4 -52.6 NA NA NA
2noj 1 P01024 98.98 0.0 X-RAY
 2007-08-14 ASP A:39 A:1029 46.0 0.307 H -77.8 -50.2 12.0 0.08 0.227 B:Q99UV2:0.227
 HOH
 9.234
 OD2
 O
ASP C:39 C:1029 46.0 0.307 I -77.5 -46.5 NA NA NA
ASP E:39 E:1029 48.0 0.32 H -78.0 -36.9 NA NA NA
ASP G:39 G:1029 39.0 0.26 H -74.3 -43.0 NA NA NA
3d5r 1 P01024 98.98 0.0 X-RAY
 2008-09-09 ASP A:39 A:40 45.0 0.3 H -66.7 -51.2 9.0 0.06 0.24 B:A6QG59:0.24
 HOH
 3.191
 O
 O
ASP C:39 B:40 46.0 0.307 H -67.2 -53.1 NA NA NA
3d5s 1 P01024 98.98 0.0 X-RAY
 2008-09-16 ASP A:39 A:40 45.0 0.3 H -69.7 -50.1 25.0 0.167 0.133 B:A6QG59:0.133
 HOH
 5.446
 OD2
 O
ASP C:39 B:40 44.0 0.293 H -69.7 -48.9 NA NA NA
1c3d 1 P01024 99.32 0.0 X-RAY
 1998-10-07 ASP A:36 A:36 38.0 0.253 H -63.7 -59.0 38.0 0.253 0.0 GOL
HOH
 9.361
4.376
 OD2
OD2
 O1
O
2xqw 1 P01024 99.32 0.0 X-RAY
 2011-02-02 ASP A:36 A:36 41.0 0.273 H -63.2 -48.0 41.0 0.273 0.0 HOH
 2.760
 O
 O
ASP B:36 B:36 43.0 0.287 H -67.4 -49.5 14.0 0.093 0.194 C:P08603:0.193
 HOH
 3.014
 O
 O
1qqf 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 ASP A:20 A:1029 42.0 0.28 H -62.9 -53.6 42.0 0.28 0.0 HOH
 2.691
 OD2
 O
1qsj 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 ASP A:20 A:1029 38.0 0.253 H -65.1 -59.6 38.0 0.253 0.0 HOH
 2.788
 O
 O
ASP B:20 B:1029 35.0 0.233 H -67.6 -60.0 35.0 0.233 0.0 HOH
 2.471
 OD2
 O
ASP C:20 C:1029 38.0 0.253 H -66.9 -60.0 NA NA NA
ASP D:20 D:1029 36.0 0.24 H -66.1 -60.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 ASP A:1029 A:1029 47.0 0.313 H -66.9 -48.4