Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6697482 . G A CCDS32883.1:NM_000064.2:c.2669cCc>cTc_NP_000055.2:p.890P>L Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 PRO B:219 B:890 53.0 0.366 T -68.7 147.5 53.0 0.366 0.0
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 PRO B:218 B:868 50.0 0.345 T -60.0 148.3 47.0 0.324 0.021 A:P01024:0.021
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 PRO B:142 B:868 56.0 0.386 S -71.5 173.8 56.0 0.386 0.0
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 PRO B:142 B:868 43.0 0.297 T -62.2 146.0 43.0 0.297 0.0 HOH
 8.000
 CB
 O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 PRO B:142 B:868 47.0 0.324 T -63.5 141.8 21.0 0.145 0.179 P:Q6GFB4:0.179
PRO D:142 D:868 47.0 0.324 T -63.5 141.8 NA NA NA
PRO F:142 F:868 47.0 0.324 T -63.6 141.8 NA NA NA
PRO H:142 H:868 47.0 0.324 T -63.5 141.8 23.0 0.159 0.165 N:Q6GFB4:0.166
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 PRO B:142 B:868 45.0 0.31 T -70.0 155.8 16.0 0.11 0.2 F:None:0.2
PRO D:142 D:868 50.0 0.345 T -68.7 147.0 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 PRO B:142 B:868 54.0 0.372 T -70.3 137.7 54.0 0.372 0.0
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 PRO B:142 B:890 43.0 0.297 T -60.8 150.5 43.0 0.297 0.0
PRO G:142 F:890 47.0 0.324 T -60.8 150.5 47.0 0.324 0.0
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 PRO B:142 B:890 41.0 0.283 T -60.9 150.8 41.0 0.283 0.0
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 PRO F:142 B:868 45.0 0.31 T -66.1 147.4 22.0 0.152 0.158 L:A0A0H2DUF0:0.159
PRO H:142 H:868 44.0 0.303 T -64.1 145.3 23.0 0.159 0.144 K:A0A0H2DUF0:0.145
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 PRO H:142 B:868 43.0 0.297 T -71.1 151.3 23.0 0.159 0.138 N:A0A0H2DUF0:0.138
PRO J:142 H:868 43.0 0.297 T -71.7 151.6 20.0 0.138 0.159 M:A0A0H2DUF0:0.159
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 PRO B:142 B:868 39.0 0.269 T -61.6 154.2 39.0 0.269 0.0 HOH
 6.504
 O
 O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 PRO B:142 B:868 51.0 0.352 T -59.5 135.8 51.0 0.352 0.0
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 PRO B:142 B:868 53.0 0.366 T -62.9 139.9 53.0 0.366 0.0
PRO D:142 D:868 55.0 0.379 T -63.0 140.2 NA NA NA
PRO F:142 F:868 54.0 0.372 T -62.7 139.9 NA NA NA
PRO H:142 H:868 54.0 0.372 T -62.7 140.1 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 PRO B:142 B:890 43.0 0.297 T -60.5 150.6 43.0 0.297 0.0
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 PRO B:142 B:890 44.0 0.303 T -64.5 146.1 44.0 0.303 0.0
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 PRO B:142 B:890 43.0 0.297 S -62.8 142.2 NA NA NA
PRO E:142 E:890 46.0 0.317 S -62.7 142.2 46.0 0.317 0.0
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 PRO B:142 B:890 43.0 0.297 T -59.7 136.1 43.0 0.297 0.0
PRO D:142 D:890 51.0 0.352 T -59.2 137.1 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 PRO B:142 B:890 40.0 0.276 T -60.8 150.5 40.0 0.276 0.0 GOL
 6.454
 C
 C3
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 PRO B:142 B:890 43.0 0.297 T -66.5 147.2 43.0 0.297 0.0
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 PRO B:142 B:890 42.0 0.29 T -66.6 147.3 42.0 0.29 0.0
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 PRO B:139 B:868 56.0 0.386 T -62.3 146.7 56.0 0.386 0.0
PRO D:139 D:868 56.0 0.386 T -62.4 146.9 NA NA NA
2ice 2 P01024 100.0 2e-138 X-RAY
 2006-11-07 PRO B:142 B:868 50.0 0.345 S -62.5 158.7 50.0 0.345 0.0
PRO F:142 E:868 44.0 0.303 T -65.8 141.1 NA NA NA
3l3o 2 P01024 100.0 2e-138 X-RAY
 2010-08-04 PRO B:142 B:868 36.0 0.248 S -84.4 165.0 36.0 0.248 0.0
PRO H:142 E:868 35.0 0.241 S -84.4 165.0 NA NA NA
3nms 4 P01024 100.0 2e-138 X-RAY
 2010-08-04 PRO D:142 B:868 41.0 0.283 S -86.7 161.1 41.0 0.283 0.0
3ohx 2 P01024 100.0 2e-138 X-RAY
 2010-09-01 PRO B:142 B:868 36.0 0.248 S -84.4 164.9 36.0 0.248 0.0
PRO D:142 E:868 35.0 0.241 S -84.5 165.0 NA NA NA
3t4a 2 P01024 100.0 2e-138 X-RAY
 2011-11-23 PRO B:142 B:868 43.0 0.297 S -68.6 169.9 43.0 0.297 0.0
PRO E:142 E:868 43.0 0.297 S -70.5 169.5 NA NA NA
2a74 2 P01024 100.0 5e-125 X-RAY
 2005-09-27 PRO B:142 B:868 46.0 0.317 T -51.8 144.7 46.0 0.317 0.0
PRO E:142 E:868 55.0 0.379 T -53.2 138.3 NA NA NA
2qki 2 P01024 100.0 5e-125 X-RAY
 2007-08-14 PRO B:142 B:868 43.0 0.297 T -57.7 150.5 43.0 0.297 0.0 HOH
 7.148
 CB
 O
PRO E:142 E:868 50.0 0.345 T -56.1 143.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 PRO A:890 A:890 54.0 0.372 T -55.7 145.3