Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6697495 . C A CCDS32883.1:NM_000064.2:c.2656Gta>Tta_NP_000055.2:p.886V>L Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 VAL B:215 B:886 26.0 0.168 E -125.9 166.3 26.0 0.168 0.0
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 VAL B:214 B:864 27.0 0.174 E -142.7 146.9 27.0 0.174 0.0
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 VAL B:138 B:864 26.0 0.168 E -142.9 159.7 26.0 0.168 0.0
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 VAL B:138 B:864 16.0 0.103 E -130.1 157.9 16.0 0.103 0.0 GOL
 9.181
 N
 O2
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 VAL B:138 B:864 30.0 0.194 -96.1 172.3 23.0 0.148 0.046 P:Q6GFB4:0.045
VAL D:138 D:864 28.0 0.181 -96.0 172.2 NA NA NA
VAL F:138 F:864 28.0 0.181 -96.1 172.2 NA NA NA
VAL H:138 H:864 26.0 0.168 -96.1 172.2 21.0 0.135 0.033 N:Q6GFB4:0.032
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 VAL B:138 B:864 24.0 0.155 E -128.4 157.7 24.0 0.155 0.0
VAL D:138 D:864 9.0 0.058 E -98.5 166.5 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 VAL B:138 B:864 26.0 0.168 -97.9 164.5 26.0 0.168 0.0
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 VAL B:138 B:886 21.0 0.135 E -113.4 166.2 21.0 0.135 0.0
VAL G:138 F:886 25.0 0.161 E -112.9 166.7 25.0 0.161 0.0
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 VAL B:138 B:886 14.0 0.09 E -113.5 166.2 14.0 0.09 0.0
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 VAL F:138 B:864 23.0 0.148 E -126.1 165.9 22.0 0.142 0.006 L:A0A0H2DUF0:0.006
VAL H:138 H:864 24.0 0.155 E -125.8 165.3 24.0 0.155 0.0
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 VAL H:138 B:864 23.0 0.148 E -124.9 171.4 23.0 0.148 0.0
VAL J:138 H:864 27.0 0.174 E -126.1 173.4 27.0 0.174 0.0
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 VAL B:138 B:864 12.0 0.077 E -135.6 166.3 12.0 0.077 0.0 HOH
 3.537
 C
 O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 VAL B:138 B:864 15.0 0.097 E -140.8 154.7 15.0 0.097 0.0
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 VAL B:138 B:864 17.0 0.11 E -119.8 166.3 17.0 0.11 0.0
VAL D:138 D:864 19.0 0.123 E -119.9 166.5 NA NA NA
VAL F:138 F:864 19.0 0.123 E -119.5 166.8 NA NA NA
VAL H:138 H:864 18.0 0.116 E -120.1 166.8 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 VAL B:138 B:886 3.0 0.019 E -113.0 166.7 3.0 0.019 0.0
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 VAL B:138 B:886 20.0 0.129 E -137.8 161.1 20.0 0.129 0.0 HOH
 7.402
 CG2
 O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 VAL B:138 B:886 17.0 0.11 E -134.5 149.8 NA NA NA
VAL E:138 E:886 24.0 0.155 E -133.2 150.4 24.0 0.155 0.0
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 VAL B:138 B:886 16.0 0.103 E -141.0 155.0 16.0 0.103 0.0
VAL D:138 D:886 16.0 0.103 E -140.9 154.6 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 VAL B:138 B:886 12.0 0.077 E -126.8 163.9 12.0 0.077 0.0 GOL
HOH
 9.645
6.947
 N
N
 O2
O
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 VAL B:138 B:886 13.0 0.084 E -124.7 164.1 13.0 0.084 0.0
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 VAL B:138 B:886 13.0 0.084 E -124.7 164.1 13.0 0.084 0.0
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 VAL B:135 B:864 19.0 0.123 E -129.7 163.9 19.0 0.123 0.0
VAL D:135 D:864 19.0 0.123 E -128.5 163.2 NA NA NA
2ice 2 P01024 100.0 2e-138 X-RAY
 2006-11-07 VAL B:138 B:864 26.0 0.168 E -112.5 159.2 9.0 0.058 0.11 C:P01024:0.11
VAL F:138 E:864 30.0 0.194 E -107.5 175.9 NA NA NA
3l3o 2 P01024 100.0 2e-138 X-RAY
 2010-08-04 VAL B:138 B:864 38.0 0.245 E -128.6 162.7 29.0 0.187 0.058 G:P01024:0.058
VAL H:138 E:864 37.0 0.239 E -128.6 162.7 NA NA NA
3nms 4 P01024 100.0 2e-138 X-RAY
 2010-08-04 VAL D:138 B:864 30.0 0.194 E -132.3 147.6 24.0 0.155 0.039 B:P01024:0.039
3ohx 2 P01024 100.0 2e-138 X-RAY
 2010-09-01 VAL B:138 B:864 37.0 0.239 E -128.7 162.6 28.0 0.181 0.058 C:P01024:0.058
VAL D:138 E:864 37.0 0.239 E -128.7 162.7 NA NA NA
3t4a 2 P01024 100.0 2e-138 X-RAY
 2011-11-23 VAL B:138 B:864 39.0 0.252 E -113.8 153.5 14.0 0.09 0.162 C:P01024:0.161
VAL E:138 E:864 38.0 0.245 E -113.0 153.5 NA NA NA
2a74 2 P01024 100.0 5e-125 X-RAY
 2005-09-27 VAL B:138 B:864 29.0 0.187 E -128.4 153.9 17.0 0.11 0.077 C:P01024:0.077
 GOL
HOH
 9.301
7.114
 N
O
 O2
O
VAL E:138 E:864 30.0 0.194 E -126.2 162.6 NA NA NA
2qki 2 P01024 100.0 5e-125 X-RAY
 2007-08-14 VAL B:138 B:864 23.0 0.148 E -144.1 155.7 17.0 0.11 0.038 C:P01024:0.039
 HOH
 5.411
 N
 O
VAL E:138 E:864 21.0 0.135 E -133.8 164.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 VAL A:886 A:886 16.0 0.103 E -141.4 154.0