Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6702512 . A C CCDS32883.1:NM_000064.2:c.2324gTt>gGt_NP_000055.2:p.775V>G Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 VAL B:104 B:775 142.0 0.916 -108.8 107.2 53.0 0.342 0.574 A:P01024:0.574
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 VAL B:103 B:753 128.0 0.826 -121.0 129.9 49.0 0.316 0.51 A:P01024:0.51
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 VAL B:27 B:753 113.0 0.729 -120.1 120.8 63.0 0.406 0.323 A:P01024:0.323
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 VAL B:27 B:753 121.0 0.781 -131.5 139.2 65.0 0.419 0.362 A:P01024:0.361
 GOL
GOL
HOH
 8.578
3.286
4.408
 N
CG2
CG2
 C3
C2
O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 VAL B:27 B:753 123.0 0.794 -135.4 123.6 63.0 0.406 0.388 A:P01024:0.387
VAL D:27 D:753 122.0 0.787 -135.4 123.6 NA NA NA
VAL F:27 F:753 122.0 0.787 -135.3 123.5 NA NA NA
VAL H:27 H:753 123.0 0.794 -135.3 123.6 62.0 0.4 0.394 G:P01024:0.394
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 VAL B:27 B:753 122.0 0.787 -118.9 137.9 68.0 0.439 0.348 A:P01024:0.348
VAL D:27 D:753 121.0 0.781 -132.5 102.5 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 VAL B:27 B:753 123.0 0.794 -127.8 117.5 72.0 0.465 0.329 A:P01024:0.329
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 VAL B:27 B:775 125.0 0.806 -125.8 127.2 70.0 0.452 0.354 A:P01024:0.355
VAL G:27 F:775 125.0 0.806 -125.4 127.7 64.0 0.413 0.393 H:P08603:0.026
F:P01024:0.368
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 VAL B:27 B:775 124.0 0.8 -126.2 127.5 58.0 0.374 0.426 A:P01024:0.426
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 VAL F:27 B:753 127.0 0.819 -131.3 139.8 62.0 0.4 0.419 E:P01024:0.419
VAL H:27 H:753 129.0 0.832 -129.6 138.8 67.0 0.432 0.4 G:P01024:0.4
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 VAL H:27 B:753 123.0 0.794 -128.8 132.7 59.0 0.381 0.413 G:P01024:0.413
VAL J:27 H:753 122.0 0.787 -129.6 134.0 60.0 0.387 0.4 I:P01024:0.4
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 VAL B:27 B:753 125.0 0.806 -120.2 127.2 67.0 0.432 0.374 A:P01024:0.374
 HOH
 3.036
 N
 O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 VAL B:27 B:753 132.0 0.852 -125.2 107.3 68.0 0.439 0.413 A:P01024:0.413
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 VAL B:27 B:753 119.0 0.768 -134.7 139.8 45.0 0.29 0.478 I:P00751:0.174
A:P01024:0.368
VAL D:27 D:753 121.0 0.781 -134.6 140.3 NA NA NA
VAL F:27 F:753 121.0 0.781 -134.6 140.1 NA NA NA
VAL H:27 H:753 122.0 0.787 -135.0 139.7 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 VAL B:27 B:775 125.0 0.806 -124.8 127.7 70.0 0.452 0.354 A:P01024:0.355
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 VAL B:27 B:775 135.0 0.871 -112.5 125.0 66.0 0.426 0.445 A:P01024:0.445
 HOH
 7.433
 CG2
 O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 VAL B:27 B:775 130.0 0.839 -126.6 125.0 NA NA NA
VAL E:27 E:775 125.0 0.806 -123.7 127.6 26.0 0.168 0.638 D:P01024:0.387
F:P17927:0.252
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 VAL B:27 B:775 125.0 0.806 -125.1 108.1 57.0 0.368 0.438 A:P01024:0.374
E:P08174:0.058
VAL D:27 D:775 129.0 0.832 -125.2 107.4 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 VAL B:27 B:775 133.0 0.858 -102.2 119.8 51.0 0.329 0.529 A:P01024:0.432
C:Q76U65:0.09
 HOH
 2.936
 N
 O
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 VAL B:27 B:775 126.0 0.813 -132.4 116.3 63.0 0.406 0.407 A:P01024:0.406
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 VAL B:27 B:775 128.0 0.826 -132.4 116.3 69.0 0.445 0.381 A:None:0.381
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 VAL B:24 B:753 121.0 0.781 -125.0 146.0 43.0 0.277 0.504 A:P01024:0.387
E:P00751:0.206
VAL D:24 D:753 123.0 0.794 -129.8 145.2 NA NA NA
2ice 2 P01024 100.0 2e-138 X-RAY
 2006-11-07 VAL B:27 B:753 118.0 0.761 -119.3 135.8 67.0 0.432 0.329 A:P01024:0.329
VAL F:27 E:753 126.0 0.813 -116.7 129.7 NA NA NA
3l3o 2 P01024 100.0 2e-138 X-RAY
 2010-08-04 VAL B:27 B:753 126.0 0.813 -132.6 113.4 74.0 0.477 0.336 A:P01024:0.335
VAL H:27 E:753 126.0 0.813 -132.6 113.3 NA NA NA
3nms 4 P01024 100.0 2e-138 X-RAY
 2010-08-04 VAL D:27 B:753 130.0 0.839 -159.1 92.0 62.0 0.4 0.439 A:P01024:0.439
3ohx 2 P01024 100.0 2e-138 X-RAY
 2010-09-01 VAL B:27 B:753 124.0 0.8 -132.6 113.3 72.0 0.465 0.335 A:P01024:0.335
VAL D:27 E:753 124.0 0.8 -132.6 113.4 NA NA NA
3t4a 2 P01024 100.0 2e-138 X-RAY
 2011-11-23 VAL B:27 B:753 118.0 0.761 -136.9 119.9 70.0 0.452 0.309 A:P01024:0.31
VAL E:27 E:753 120.0 0.774 -134.6 121.5 NA NA NA
2a74 2 P01024 100.0 5e-125 X-RAY
 2005-09-27 VAL B:27 B:753 126.0 0.813 -118.6 128.5 60.0 0.387 0.426 A:P01024:0.426
 HOH
 2.773
 N
 O
VAL E:27 E:753 119.0 0.768 -110.3 135.8 NA NA NA
2qki 2 P01024 100.0 5e-125 X-RAY
 2007-08-14 VAL B:27 B:753 126.0 0.813 -123.6 131.4 85.0 0.548 0.265 A:P01024:0.265
 HOH
 3.105
 N
 O
VAL E:27 E:753 126.0 0.813 -125.4 123.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 VAL A:775 A:775 64.0 0.413 E -134.3 123.5