Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6702542 . C A CCDS32883.1:NM_000064.2:c.2294aGt>aTt_NP_000055.2:p.765S>I Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 SER B:94 B:765 92.0 0.8 -140.6 -161.7 1.0 0.009 0.791 A:P01024:0.791
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 SER B:93 B:743 113.0 0.983 -126.6 -27.2 4.0 0.035 0.948 A:P01024:0.948
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 SER B:17 B:743 35.0 0.304 -112.8 -35.5 35.0 0.304 0.0
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 SER B:17 B:743 33.0 0.287 -123.5 -24.9 24.0 0.209 0.078 C:P08603:0.078
 GOL
HOH
 8.734
4.813
 O
O
 O2
O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 SER B:17 B:743 42.0 0.365 -122.2 -33.7 42.0 0.365 0.0
SER D:17 D:743 44.0 0.383 -122.1 -33.7 NA NA NA
SER F:17 F:743 43.0 0.374 -122.1 -33.9 NA NA NA
SER H:17 H:743 44.0 0.383 -122.2 -33.8 44.0 0.383 0.0
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 SER B:17 B:743 36.0 0.313 -135.9 -32.9 36.0 0.313 0.0
SER D:17 D:743 37.0 0.322 -136.0 -28.1 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 SER B:17 B:743 42.0 0.365 -104.0 9.8 42.0 0.365 0.0
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 SER B:17 B:765 35.0 0.304 -136.8 -10.7 30.0 0.261 0.043 C:P08603:0.043
SER G:17 F:765 38.0 0.33 -136.8 -10.9 32.0 0.278 0.052 H:P08603:0.052
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 SER B:17 B:765 37.0 0.322 -136.4 -10.4 33.0 0.287 0.035 C:P08603:0.035
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 SER F:17 B:743 46.0 0.4 -145.0 -17.4 43.0 0.374 0.026 K:A0A0H2DUF0:0.026
SER H:17 H:743 45.0 0.391 -144.6 -16.1 40.0 0.348 0.043 L:A0A0H2DUF0:0.043
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 SER H:17 B:743 47.0 0.409 -142.5 -21.3 46.0 0.4 0.009 M:A0A0H2DUF0:0.009
SER J:17 H:743 48.0 0.417 -142.4 -20.4 46.0 0.4 0.017 N:A0A0H2DUF0:0.017
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 SER B:17 B:743 25.0 0.217 -150.2 -14.7 25.0 0.217 0.0 HOH
 2.569
 O
 O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 SER B:17 B:743 44.0 0.383 -124.7 -31.6 44.0 0.383 0.0
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 SER B:17 B:743 40.0 0.348 -156.0 -35.3 31.0 0.27 0.078 I:P00751:0.078
SER D:17 D:743 42.0 0.365 -160.0 -35.5 NA NA NA
SER F:17 F:743 42.0 0.365 -143.5 -31.5 NA NA NA
SER H:17 H:743 43.0 0.374 -146.7 -33.6 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 SER B:17 B:765 34.0 0.296 -136.5 -10.6 34.0 0.296 0.0
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 SER B:17 B:765 32.0 0.278 -143.7 -10.1 32.0 0.278 0.0 HOH
 8.384
 O
 O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 SER B:17 B:765 42.0 0.365 -100.5 -53.8 NA NA NA
SER E:17 E:765 47.0 0.409 -98.2 -24.2 37.0 0.322 0.087 F:P17927:0.087
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 SER B:17 B:765 35.0 0.304 -124.3 -31.2 35.0 0.304 0.0
SER D:17 D:765 40.0 0.348 -125.5 -33.3 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 SER B:17 B:765 35.0 0.304 -147.6 -18.9 5.0 0.043 0.261 C:Q76U65:0.261
 NA
CL
HOH
 9.882
7.742
2.711
 N
OG
OG
 NA
CL
O
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 SER B:17 B:765 48.0 0.417 -129.1 -21.3 48.0 0.417 0.0
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 SER B:17 B:765 58.0 0.504 -129.1 -21.3 58.0 0.504 0.0
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 SER B:14 B:743 36.0 0.313 -155.0 -38.0 22.0 0.191 0.122 E:P00751:0.122
SER D:14 D:743 43.0 0.374 -149.0 -31.9 NA NA NA
2ice 2 P01024 100.0 2e-138 X-RAY
 2006-11-07 SER B:17 B:743 30.0 0.261 -139.6 -26.4 30.0 0.261 0.0
SER F:17 E:743 38.0 0.33 -133.1 4.6 NA NA NA
3l3o 2 P01024 100.0 2e-138 X-RAY
 2010-08-04 SER B:17 B:743 39.0 0.339 -144.6 -21.2 38.0 0.33 0.009 C:Q931M7:0.009
SER H:17 E:743 39.0 0.339 -144.6 -21.2 NA NA NA
3nms 4 P01024 100.0 2e-138 X-RAY
 2010-08-04 SER D:17 B:743 35.0 0.304 -167.2 -32.5 31.0 0.27 0.034 C:Q931M7:0.035
3ohx 2 P01024 100.0 2e-138 X-RAY
 2010-09-01 SER B:17 B:743 39.0 0.339 -144.5 -21.2 37.0 0.322 0.017 E:Q931M7:0.017
SER D:17 E:743 39.0 0.339 -144.6 -21.2 NA NA NA
3t4a 2 P01024 100.0 2e-138 X-RAY
 2011-11-23 SER B:17 B:743 44.0 0.383 -144.7 -21.1 39.0 0.339 0.044 G:Q99UU9:0.043
SER E:17 E:743 45.0 0.391 -145.3 -23.7 NA NA NA
2a74 2 P01024 100.0 5e-125 X-RAY
 2005-09-27 SER B:17 B:743 47.0 0.409 -141.5 -15.8 47.0 0.409 0.0 GOL
HOH
 8.393
2.669
 CB
O
 O3
O
SER E:17 E:743 43.0 0.374 -146.6 -10.6 NA NA NA
2qki 2 P01024 100.0 5e-125 X-RAY
 2007-08-14 SER B:17 B:743 42.0 0.365 -135.1 -18.5 42.0 0.365 0.0 BR
GOL
HOH
 6.101
5.090
2.577
 O
N
O
 BR
O2
O
SER E:17 E:743 37.0 0.322 -148.6 -8.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 SER A:765 A:765 67.0 0.583 -152.5 -24.1