Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 6707846 | . | G | A | CCDS32883.1:NM_000064.2:c.1940aCg>aTg_NP_000055.2:p.647T>M | Homo sapiens complement component 3 (C3), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 2wii | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2009-06-09 | THR | A:625 | A:625 | 6.0 | 0.043 | E | -144.0 | 124.3 | 6.0 | 0.043 | 0.0 |
GOL HOH |
9.784 6.408 |
OG1 OG1 |
O3 O |
||
| 2win | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2009-06-09 | THR | A:625 | A:625 | 7.0 | 0.05 | E | -151.4 | 124.9 | 7.0 | 0.05 | 0.0 | ||||||
| THR | C:625 | C:625 | 6.0 | 0.043 | E | -151.4 | 124.9 | NA | NA | NA | |||||||||||||
| THR | E:625 | E:625 | 6.0 | 0.043 | E | -151.4 | 124.8 | NA | NA | NA | |||||||||||||
| THR | G:625 | G:625 | 9.0 | 0.064 | E | -151.5 | 125.0 | 9.0 | 0.064 | 0.0 | |||||||||||||
| 2xwj | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2011-01-12 | THR | A:625 | A:625 | 5.0 | 0.036 | E | -141.2 | 119.3 | 5.0 | 0.036 | 0.0 | ||||||
| THR | C:625 | C:625 | 8.0 | 0.057 | B | -141.0 | 120.6 | NA | NA | NA | |||||||||||||
| THR | E:625 | E:625 | 8.0 | 0.057 | B | -140.9 | 120.9 | NA | NA | NA | |||||||||||||
| THR | G:625 | G:625 | 4.0 | 0.029 | E | -140.7 | 121.1 | NA | NA | NA | |||||||||||||
| 3l3o | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2010-08-04 | THR | A:625 | A:625 | 4.0 | 0.029 | E | -120.7 | 124.2 | 4.0 | 0.029 | 0.0 | ||||||
| THR | F:625 | D:625 | 4.0 | 0.029 | E | -120.7 | 124.2 | NA | NA | NA | |||||||||||||
| 3l5n | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2010-08-04 | THR | A:625 | A:625 | 11.0 | 0.079 | E | -166.6 | 155.7 | 11.0 | 0.079 | 0.0 | ||||||
| 3nms | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2010-08-04 | THR | A:625 | A:625 | 4.0 | 0.029 | E | -120.6 | 124.2 | 4.0 | 0.029 | 0.0 | ||||||
| 3ohx | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2010-09-01 | THR | A:625 | A:625 | 4.0 | 0.029 | E | -120.7 | 124.2 | 4.0 | 0.029 | 0.0 | ||||||
| THR | H:625 | D:625 | 4.0 | 0.029 | E | -120.7 | 124.2 | NA | NA | NA | |||||||||||||
| 3t4a | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2011-11-23 | THR | A:625 | A:625 | 3.0 | 0.021 | E | -147.0 | 136.8 | 3.0 | 0.021 | 0.0 | ||||||
| THR | D:625 | D:625 | 4.0 | 0.029 | E | -147.0 | 136.9 | NA | NA | NA | |||||||||||||
| 5fo7 | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2016-04-06 | THR | A:625 | A:647 | 6.0 | 0.043 | E | -148.1 | 112.4 | 6.0 | 0.043 | 0.0 | ||||||
| 5fo8 | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2016-04-06 | THR | A:625 | A:647 | 5.0 | 0.036 | E | -145.2 | 129.2 | 5.0 | 0.036 | 0.0 |
HOH |
2.707 |
OG1 |
O |
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| 5fo9 | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2016-04-06 | THR | A:625 | A:647 | 5.0 | 0.036 | E | -131.9 | 140.4 | NA | NA | NA | ||||||
| THR | D:625 | D:647 | 4.0 | 0.029 | E | -132.4 | 140.3 | 4.0 | 0.029 | 0.0 | |||||||||||||
| 5foa | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2016-04-06 | THR | A:625 | A:647 | 6.0 | 0.043 | E | -126.1 | 132.4 | 6.0 | 0.043 | 0.0 | ||||||
| THR | C:625 | C:647 | 4.0 | 0.029 | E | -127.9 | 134.4 | NA | NA | NA | |||||||||||||
| 5fob | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2016-04-06 | THR | A:625 | A:647 | 3.0 | 0.021 | E | -142.2 | 138.7 | 3.0 | 0.021 | 0.0 |
HOH |
7.607 |
OG1 |
O |
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| 5o32 | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2017-06-28 | THR | A:625 | A:647 | 5.0 | 0.036 | E | -148.7 | 112.5 | 5.0 | 0.036 | 0.0 | ||||||
| THR | F:625 | E:647 | 4.0 | 0.029 | E | -148.6 | 112.5 | 4.0 | 0.029 | 0.0 | |||||||||||||
| 5o35 | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2017-06-28 | THR | A:625 | A:647 | 7.0 | 0.05 | E | -148.2 | 112.1 | 7.0 | 0.05 | 0.0 | ||||||
| 6rur | 3 | P01024 | 100.0 | 0.0 |
X-RAY |
2019-08-21 | THR | E:625 | A:625 | 8.0 | 0.057 | E | -157.0 | 134.6 | 8.0 | 0.057 | 0.0 | ||||||
| THR | G:625 | G:625 | 12.0 | 0.086 | E | -157.0 | 133.9 | 12.0 | 0.086 | 0.0 | |||||||||||||
| 6ruv | 4 | P01024 | 100.0 | 0.0 |
X-RAY |
2019-08-21 | THR | G:625 | A:625 | 9.0 | 0.064 | E | -154.1 | 130.2 | 9.0 | 0.064 | 0.0 | ||||||
| THR | I:625 | G:625 | 8.0 | 0.057 | E | -153.8 | 130.0 | 8.0 | 0.057 | 0.0 | |||||||||||||
| 7bag | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | THR | A:625 | A:625 | 5.0 | 0.036 | E | -140.8 | 128.4 | 5.0 | 0.036 | 0.0 |
HOH |
2.648 |
OG1 |
O |
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| 6ru5 | 1 | P01024 | 99.84 | 0.0 |
X-RAY |
2019-08-21 | THR | A:625 | A:647 | 7.0 | 0.05 | E | -142.5 | 156.6 | 7.0 | 0.05 | 0.0 | ||||||
| 3g6j | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2009-03-10 | THR | A:625 | A:625 | 5.0 | 0.036 | E | -148.5 | 135.7 | 5.0 | 0.036 | 0.0 | ||||||
| THR | C:625 | C:625 | 1.0 | 0.007 | E | -150.0 | 125.7 | NA | NA | NA | |||||||||||||
| 6yo6 | 1 | ? | 99.69 | 0.0 |
X-RAY |
2021-02-24 | THR | A:625 | A:647 | 5.0 | 0.036 | E | -150.8 | 136.6 | 5.0 | 0.036 | 0.0 | ||||||
| 2i07 | 1 | P01024 | 99.84 | 0.0 |
X-RAY |
2006-10-24 | THR | A:625 | A:625 | 6.0 | 0.043 | E | -128.1 | 134.2 | 6.0 | 0.043 | 0.0 | ||||||
| 6ehg | 1 | P01024 | 99.69 | 0.0 |
X-RAY |
2018-02-14 | THR | A:625 | A:647 | 6.0 | 0.043 | E | -150.8 | 136.6 | 6.0 | 0.043 | 0.0 | ||||||
| 2xwb | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2011-01-12 | THR | A:625 | A:625 | 5.0 | 0.036 | E | -144.1 | 132.9 | 5.0 | 0.036 | 0.0 | ||||||
| THR | C:625 | C:625 | 5.0 | 0.036 | E | -144.5 | 132.6 | NA | NA | NA | |||||||||||||
| 2a73 | 1 | P01024 | 99.84 | 0.0 |
X-RAY |
2005-09-27 | THR | A:625 | A:625 | 3.0 | 0.021 | E | -139.4 | 128.0 | 3.0 | 0.021 | 0.0 | ||||||
| 2a74 | 1 | P01024 | 99.84 | 0.0 |
X-RAY |
2005-09-27 | THR | A:625 | A:625 | 7.0 | 0.05 | E | -144.9 | 130.4 | 7.0 | 0.05 | 0.0 |
HOH |
2.740 |
OG1 |
O |
||
| THR | D:625 | D:625 | 6.0 | 0.043 | E | -142.8 | 132.6 | NA | NA | NA | |||||||||||||
| 2qki | 1 | P01024 | 99.84 | 0.0 |
X-RAY |
2007-08-14 | THR | A:625 | A:625 | 6.0 | 0.043 | E | -148.7 | 119.0 | 6.0 | 0.043 | 0.0 |
HOH |
7.275 |
OG1 |
O |
||
| THR | D:625 | D:625 | 5.0 | 0.036 | E | -150.2 | 134.0 | NA | NA | NA | |||||||||||||
| 2ice | 1 | P01024 | 99.84 | 0.0 |
X-RAY |
2006-11-07 | THR | A:625 | A:625 | 5.0 | 0.036 | E | -147.3 | 137.2 | 5.0 | 0.036 | 0.0 | ||||||
| THR | E:625 | D:625 | 4.0 | 0.029 | E | -143.6 | 135.8 | NA | NA | NA | |||||||||||||
| 2icf | 1 | P01024 | 99.84 | 0.0 |
X-RAY |
2006-11-07 | THR | A:625 | A:625 | 2.0 | 0.014 | -166.7 | 166.0 | 2.0 | 0.014 | 0.0 | |||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p01024-f1 | 1 | P01024 | 100.0 | 0.0 | THR | A:647 | A:647 | 13.0 | 0.093 | E | -151.5 | 140.7 | |