Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6709765 . C A CCDS32883.1:NM_000064.2:c.1775cGg>cTg_NP_000055.2:p.592R>L Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2wii 1 P01024 100.0 0.0 X-RAY
 2009-06-09 ARG A:570 A:570 145.0 0.644 -92.0 121.8 39.0 0.173 0.471 B:P01024:0.4
C:P08603:0.071
 GOL
GOL
HOH
 8.983
7.063
3.055
 NH1
NH1
NH1
 O2
C3
O
2win 1 P01024 100.0 0.0 X-RAY
 2009-06-09 ARG A:570 A:570 150.0 0.667 -97.4 133.2 61.0 0.271 0.396 B:P01024:0.396
ARG C:570 C:570 147.0 0.653 -97.3 133.2 NA NA NA
ARG E:570 E:570 149.0 0.662 -97.5 133.3 NA NA NA
ARG G:570 G:570 139.0 0.618 -97.4 133.2 51.0 0.227 0.391 H:P01024:0.391
2xwj 1 P01024 100.0 0.0 X-RAY
 2011-01-12 ARG A:570 A:570 143.0 0.636 -91.6 121.5 58.0 0.258 0.378 B:P01024:0.378
ARG C:570 C:570 144.0 0.64 -91.8 121.4 NA NA NA
ARG E:570 E:570 144.0 0.64 -92.0 121.1 NA NA NA
ARG G:570 G:570 143.0 0.636 -91.8 121.4 NA NA NA
3l3o 1 P01024 100.0 0.0 X-RAY
 2010-08-04 ARG A:570 A:570 148.0 0.658 -105.5 135.6 62.0 0.276 0.382 B:P01024:0.382
ARG F:570 D:570 146.0 0.649 -105.4 135.6 NA NA NA
3l5n 1 P01024 100.0 0.0 X-RAY
 2010-08-04 ARG A:570 A:570 145.0 0.644 -85.5 151.3 76.0 0.338 0.306 B:P01024:0.307
3nms 1 P01024 100.0 0.0 X-RAY
 2010-08-04 ARG A:570 A:570 143.0 0.636 -105.4 135.6 58.0 0.258 0.378 D:P01024:0.378
3ohx 1 P01024 100.0 0.0 X-RAY
 2010-09-01 ARG A:570 A:570 148.0 0.658 -105.5 135.6 61.0 0.271 0.387 B:P01024:0.387
ARG H:570 D:570 148.0 0.658 -105.5 135.6 NA NA NA
3t4a 1 P01024 100.0 0.0 X-RAY
 2011-11-23 ARG A:570 A:570 145.0 0.644 -87.2 132.4 56.0 0.249 0.395 B:P01024:0.396
ARG D:570 D:570 144.0 0.64 -87.2 132.4 NA NA NA
5fo7 1 P01024 100.0 0.0 X-RAY
 2016-04-06 ARG A:570 A:592 151.0 0.671 -91.4 118.4 67.0 0.298 0.373 B:P01024:0.373
5fo8 1 P01024 100.0 0.0 X-RAY
 2016-04-06 ARG A:570 A:592 141.0 0.627 -97.6 123.6 54.0 0.24 0.387 B:P01024:0.387
 EDO
HOH
 8.184
6.202
 NH1
O
 O1
O
5fo9 1 P01024 100.0 0.0 X-RAY
 2016-04-06 ARG A:570 A:592 156.0 0.693 -105.8 132.4 NA NA NA
ARG D:570 D:592 150.0 0.667 -106.8 132.8 44.0 0.196 0.471 E:P01024:0.391
F:P17927:0.084
5foa 1 P01024 100.0 0.0 X-RAY
 2016-04-06 ARG A:570 A:592 150.0 0.667 -118.0 131.2 61.0 0.271 0.396 B:P01024:0.382
E:P08174:0.013
ARG C:570 C:592 157.0 0.698 -117.2 130.2 NA NA NA
5fob 1 P01024 100.0 0.0 X-RAY
 2016-04-06 ARG A:570 A:592 146.0 0.649 -91.8 120.0 53.0 0.236 0.413 B:P01024:0.413
 HOH
 4.847
 CB
 O
5o32 1 P01024 100.0 0.0 X-RAY
 2017-06-28 ARG A:570 A:592 147.0 0.653 -91.3 118.2 38.0 0.169 0.484 B:P01024:0.378
C:P08603:0.102
ARG F:570 E:592 146.0 0.649 -91.4 118.4 36.0 0.16 0.489 H:P08603:0.102
G:P01024:0.382
5o35 1 P01024 100.0 0.0 X-RAY
 2017-06-28 ARG A:570 A:592 145.0 0.644 -91.5 118.4 38.0 0.169 0.475 B:P01024:0.382
C:P08603:0.089
6rur 3 P01024 100.0 0.0 X-RAY
 2019-08-21 ARG E:570 A:570 140.0 0.622 -99.2 131.2 50.0 0.222 0.4 F:P01024:0.4
ARG G:570 G:570 152.0 0.676 -99.4 131.0 62.0 0.276 0.4 H:P01024:0.4
6ruv 4 P01024 100.0 0.0 X-RAY
 2019-08-21 ARG G:570 A:570 139.0 0.618 -106.7 128.8 47.0 0.209 0.409 H:P01024:0.409
ARG I:570 G:570 146.0 0.649 -106.6 129.1 53.0 0.236 0.413 J:P01024:0.413
7bag 1 P01024 100.0 0.0 X-RAY
 2022-01-12 ARG A:570 A:570 147.0 0.653 -90.9 123.9 59.0 0.262 0.391 B:P01024:0.391
 HOH
 2.760
 NH1
 O
6ru5 1 P01024 99.84 0.0 X-RAY
 2019-08-21 ARG A:570 A:592 173.0 0.769 -76.5 142.6 76.0 0.338 0.431 B:P01024:0.431
3g6j 1 P01024 100.0 0.0 X-RAY
 2009-03-10 ARG A:570 A:570 164.0 0.729 -81.2 147.9 71.0 0.316 0.413 B:P01024:0.413
ARG C:570 C:570 149.0 0.662 -89.1 142.8 NA NA NA
6yo6 1 ? 99.69 0.0 X-RAY
 2021-02-24 ARG A:570 A:592 172.0 0.764 -95.8 115.6 86.0 0.382 0.382 B:None:0.382
2i07 1 P01024 99.84 0.0 X-RAY
 2006-10-24 ARG A:570 A:570 133.0 0.591 -117.9 130.7 52.0 0.231 0.36 B:P01024:0.36
6ehg 1 P01024 99.69 0.0 X-RAY
 2018-02-14 ARG A:570 A:592 164.0 0.729 -95.9 115.5 78.0 0.347 0.382 B:P01024:0.382
2xwb 1 P01024 100.0 0.0 X-RAY
 2011-01-12 ARG A:570 A:570 147.0 0.653 -93.6 130.8 57.0 0.253 0.4 B:P01024:0.4
ARG C:570 C:570 151.0 0.671 -93.3 130.3 NA NA NA
2a73 1 P01024 99.84 0.0 X-RAY
 2005-09-27 ARG A:570 A:570 155.0 0.689 -101.8 129.9 69.0 0.307 0.382 B:P01024:0.382
2a74 1 P01024 99.84 0.0 X-RAY
 2005-09-27 ARG A:570 A:570 141.0 0.627 -81.6 128.7 57.0 0.253 0.374 B:P01024:0.373
 HOH
 6.204
 O
 O
ARG D:570 D:570 138.0 0.613 -88.2 123.4 NA NA NA
2qki 1 P01024 99.84 0.0 X-RAY
 2007-08-14 ARG A:570 A:570 151.0 0.671 -85.8 128.7 71.0 0.316 0.355 B:P01024:0.356
 BR
HOH
 6.452
2.954
 NH1
NH1
 BR
O
ARG D:570 D:570 129.0 0.573 -99.7 122.0 NA NA NA
2ice 1 P01024 99.84 0.0 X-RAY
 2006-11-07 ARG A:570 A:570 139.0 0.618 -93.2 126.7 55.0 0.244 0.374 B:P01024:0.373
ARG E:570 D:570 139.0 0.618 -86.3 127.7 NA NA NA
2icf 1 P01024 99.84 0.0 X-RAY
 2006-11-07 ARG A:570 A:570 137.0 0.609 -121.0 132.7 51.0 0.227 0.382 B:P01024:0.382

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 ARG A:592 A:592 62.0 0.276 E -89.9 122.5