Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 7184490 . G A CCDS12176.1:NM_000208.2:c.811Ccg>Tcg_NP_000199.2:p.271P>S Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7bw7 1 P06213 100.0 0.0 EM
 2021-04-14 PRO A:244 A:244 85.0 0.586 T -94.5 47.4 85.0 0.586 0.0
PRO B:244 NA:NA DO NA DO DO DO NA NA NA
7bw8 1 P06213 100.0 0.0 EM
 2021-04-14 PRO A:244 A:244 72.0 0.497 T -84.1 40.7 72.0 0.497 0.0
PRO B:244 NA:NA DO NA DO DO DO NA NA NA
7bwa 1 P06213 100.0 0.0 EM
 2021-04-14 PRO A:244 A:244 67.0 0.462 T -90.5 31.0 67.0 0.462 0.0
PRO B:244 C:244 67.0 0.462 T -90.5 31.0 NA NA NA
7pg0 1 P06213 99.13 0.0 EM
 2022-02-02 PRO A:271 A:244 62.0 0.428 T -53.2 -41.1 62.0 0.428 0.0
PRO B:271 B:244 60.0 0.414 T -55.7 -39.2 60.0 0.414 0.0
7pg2 1 P06213 99.13 0.0 EM
 2022-02-02 PRO A:271 A:244 79.0 0.545 T -79.7 7.0 79.0 0.545 0.0
PRO B:271 B:244 63.0 0.434 T -98.6 19.1 63.0 0.434 0.0
7pg3 1 P06213 99.13 0.0 EM
 2022-02-02 PRO A:271 A:244 75.0 0.517 T -56.7 -24.5 75.0 0.517 0.0
PRO B:271 B:244 71.0 0.49 T -78.0 1.1 71.0 0.49 0.0
7pg4 1 P06213 99.13 0.0 EM
 2022-02-02 PRO A:271 A:244 88.0 0.607 T -39.0 -55.2 88.0 0.607 0.0
PRO B:271 B:244 56.0 0.386 T -84.3 5.4 56.0 0.386 0.0
6pxv 1 P06213 98.6 0.0 EM
 2019-09-04 PRO A:244 A:244 88.0 0.607 T -94.9 43.8 88.0 0.607 0.0
PRO B:244 C:244 88.0 0.607 T -95.0 43.8 88.0 0.607 0.0
6pxw 1 P06213 98.6 0.0 EM
 2019-09-04 PRO A:244 A:244 86.0 0.593 T -94.9 43.8 86.0 0.593 0.0
PRO B:244 B:244 88.0 0.607 T -95.0 43.8 88.0 0.607 0.0
6ce7 1 P06213 99.89 0.0 EM
 2018-03-14 PRO A:244 B:244 92.0 0.634 T -80.2 5.7 92.0 0.634 0.0
PRO B:244 A:244 83.0 0.572 T -87.0 17.9 83.0 0.572 0.0
6ce9 1 P06213 98.6 0.0 EM
 2018-03-14 PRO A:244 A:244 81.0 0.559 T -94.6 46.4 81.0 0.559 0.0 NAG
 6.969
 CG
 O7
PRO B:244 B:244 82.0 0.566 T -94.6 46.4 82.0 0.566 0.0 NAG
 6.896
 CG
 O7
6ceb 1 P06213 98.6 0.0 EM
 2018-03-14 PRO A:244 A:244 86.0 0.593 T -95.7 48.3 86.0 0.593 0.0 NAG
 7.475
 CG
 O7
PRO B:244 B:244 80.0 0.552 T -95.2 47.4 80.0 0.552 0.0 NAG
 6.700
 CG
 O7
6hn4 1 P06213,P03069 95.7 0.0 EM
 2018-11-21 PRO A:244 NA:NA DO NA DO DO DO NA NA NA
PRO B:244 F:244 95.0 0.655 T -94.7 30.8 95.0 0.655 0.0
6hn5 3 P06213,P03069 95.7 0.0 EM
 2018-11-21 PRO C:244 E:244 102.0 0.703 T -96.0 -10.8 102.0 0.703 0.0 NAG
 9.129
 O
 C8
PRO D:244 NA:NA DO NA DO DO DO NA NA NA
4zxb 5 P06213 95.48 0.0 X-RAY
 2016-02-24 PRO E:244 E:244 94.0 0.648 T -96.4 31.4 43.0 0.297 0.351 B:P01837:0.255
A:U5LP42:0.186
 NAG
 7.718
 CG
 O7
6sof 1 P06213 100.0 0.0 EM
 2019-11-13 PRO A:244 A:244 82.0 0.566 T -76.7 -6.1 82.0 0.566 0.0
PRO C:244 C:244 84.0 0.579 T -101.8 -11.7 84.0 0.579 0.0
7qid 1 P06213 100.0 0.0 EM
 2022-02-02 PRO A:244 A:244 74.0 0.51 T -81.7 -6.5 74.0 0.51 0.0
PRO C:244 C:244 80.0 0.552 T -56.7 -26.2 80.0 0.552 0.0
5kqv 5 P06213 99.83 0.0 X-RAY
 2017-07-19 PRO E:244 E:244 90.0 0.621 T -96.4 33.8 90.0 0.621 0.0
PRO F:244 F:244 91.0 0.628 T -96.5 33.9 91.0 0.628 0.0
2hr7 1 P06213 99.59 0.0 X-RAY
 2006-08-15 PRO A:244 A:244 94.0 0.648 T -96.1 34.5 94.0 0.648 0.0 NAG
FUC
HOH
 6.770
8.596
2.429
 CG
CD
O
 O7
C4
O
PRO B:244 B:244 94.0 0.648 T -96.3 33.2 94.0 0.648 0.0 NAG
HOH
 7.102
2.197
 CG
O
 O7
O
4oga 5 P06213 99.68 0.0 X-RAY
 2014-08-27 PRO E:244 E:244 93.0 0.641 T -96.2 31.6 44.0 0.303 0.338 C:None:0.172
D:None:0.221
 NAG
 7.664
 CG
 O7
4xss 2 P06213 99.68 0.0 X-RAY
 2015-06-10 PRO B:244 E:244 91.0 0.628 T -97.9 31.6 91.0 0.628 0.0 NAG
 6.903
 CG
 O7
4xst 1 P06213 99.68 0.0 X-RAY
 2015-06-10 PRO A:244 E:244 91.0 0.628 T -93.1 32.0 91.0 0.628 0.0 NAG
 6.317
 CG
 O7
5j3h 4 P06213 99.68 0.0 X-RAY
 2016-06-15 PRO D:244 E:244 89.0 0.614 T -99.9 29.5 34.0 0.234 0.38 B:None:0.221
C:None:0.276
 NAG
 8.014
 CG
 C8
6vep 5 P06213 99.68 0.0 X-RAY
 2020-06-03 PRO E:244 E:244 92.0 0.634 T -94.4 23.0 52.0 0.359 0.275 D:None:0.221
C:None:0.138
 NAG
 7.401
 CG
 O7
PRO K:244 K:244 90.0 0.621 T -95.3 22.9 NA NA NA
PRO Q:244 Q:244 92.0 0.634 T -94.4 23.0 NA NA NA
PRO W:244 W:244 94.0 0.648 T -93.7 21.9 NA NA NA
6veq 3 P06213 99.68 0.0 X-RAY
 2020-06-03 PRO C:244 E:244 97.0 0.669 T -95.1 36.4 55.0 0.379 0.29 E:None:0.11
F:None:0.248
 NAG
 8.167
 CG
 C8
PRO G:244 K:244 99.0 0.683 T -94.9 36.3 NA NA NA
7kd6 4 P06213 99.68 0.0 X-RAY
 2021-10-13 PRO D:244 E:244 95.0 0.655 T -88.3 15.5 50.0 0.345 0.31 B:None:0.152
C:None:0.255
 NAG
HOH
 7.466
3.847
 CG
CG
 O7
O
PRO I:244 K:244 94.0 0.648 T -91.9 28.2 NA NA NA
PRO N:244 Q:244 94.0 0.648 T -94.0 18.2 NA NA NA
PRO S:244 W:244 95.0 0.655 T -90.7 19.0 NA NA NA
3w11 5 P06213 99.68 0.0 X-RAY
 2013-01-09 PRO E:244 E:244 97.0 0.669 T -89.7 24.7 39.0 0.269 0.4 D:None:0.248
C:None:0.214
 NAG
 8.148
 CG
 O7
3w12 1 P06213 99.68 0.0 X-RAY
 2013-01-09 PRO A:244 E:244 86.0 0.593 T -91.1 28.2 40.0 0.276 0.317 B:None:0.159
C:None:0.207
 NAG
 8.029
 CG
 O7
3w13 1 P06213 99.68 0.0 X-RAY
 2013-01-09 PRO A:244 E:244 90.0 0.621 T -92.5 25.5 44.0 0.303 0.318 B:None:0.186
C:None:0.207
 NAG
 8.204
 CG
 O7

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06213-f1 1 P06213 100.0 0.0 PRO A:271 A:271 95.0 0.655 T -99.3 28.8