Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 7184495 . G A CCDS12176.1:NM_000208.2:c.806cCg>cTg_NP_000199.2:p.269P>L Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7bw7 1 P06213 100.0 0.0 EM
2021-04-14 PRO A:242 A:242 92.0 0.634 -69.0 168.0 92.0 0.634 0.0
PRO B:242 NA:NA DO NA DO DO DO NA NA NA
7bw8 1 P06213 100.0 0.0 EM
2021-04-14 PRO A:242 A:242 87.0 0.6 -68.0 162.8 87.0 0.6 0.0
PRO B:242 NA:NA DO NA DO DO DO NA NA NA
7bwa 1 P06213 100.0 0.0 EM
2021-04-14 PRO A:242 A:242 59.0 0.407 -68.6 152.7 59.0 0.407 0.0
PRO B:242 C:242 57.0 0.393 -68.6 152.7 NA NA NA
7pg0 1 P06213 99.13 0.0 EM
2022-02-02 PRO A:269 A:242 56.0 0.386 -64.7 161.4 56.0 0.386 0.0
PRO B:269 B:242 59.0 0.407 -57.8 143.8 59.0 0.407 0.0
7pg2 1 P06213 99.13 0.0 EM
2022-02-02 PRO A:269 A:242 69.0 0.476 -60.7 153.9 69.0 0.476 0.0
PRO B:269 B:242 69.0 0.476 -67.6 166.4 69.0 0.476 0.0
7pg3 1 P06213 99.13 0.0 EM
2022-02-02 PRO A:269 A:242 64.0 0.441 -49.4 156.4 64.0 0.441 0.0
PRO B:269 B:242 61.0 0.421 -76.5 126.7 61.0 0.421 0.0
7pg4 1 P06213 99.13 0.0 EM
2022-02-02 PRO A:269 A:242 70.0 0.483 -48.1 133.4 70.0 0.483 0.0
PRO B:269 B:242 56.0 0.386 -85.7 149.2 56.0 0.386 0.0
6pxv 1 P06213 98.6 0.0 EM
2019-09-04 PRO A:242 A:242 56.0 0.386 -77.5 156.9 56.0 0.386 0.0
PRO B:242 C:242 56.0 0.386 -77.5 156.9 56.0 0.386 0.0
6pxw 1 P06213 98.6 0.0 EM
2019-09-04 PRO A:242 A:242 55.0 0.379 -77.5 156.9 55.0 0.379 0.0
PRO B:242 B:242 56.0 0.386 -77.5 156.9 56.0 0.386 0.0
6ce7 1 P06213 99.89 0.0 EM
2018-03-14 PRO A:242 B:242 62.0 0.428 -87.4 168.1 62.0 0.428 0.0
PRO B:242 A:242 56.0 0.386 -62.8 144.2 56.0 0.386 0.0
6ce9 1 P06213 98.6 0.0 EM
2018-03-14 PRO A:242 A:242 62.0 0.428 -73.0 155.3 62.0 0.428 0.0
PRO B:242 B:242 63.0 0.434 -73.0 155.3 63.0 0.434 0.0
6ceb 1 P06213 98.6 0.0 EM
2018-03-14 PRO A:242 A:242 59.0 0.407 -71.4 156.2 59.0 0.407 0.0
PRO B:242 B:242 54.0 0.372 -71.2 155.1 54.0 0.372 0.0
6hn4 1 P06213,P03069 95.7 0.0 EM
2018-11-21 PRO A:242 NA:NA DO NA DO DO DO NA NA NA
PRO B:242 F:242 60.0 0.414 -79.1 154.4 60.0 0.414 0.0
6hn5 3 P06213,P03069 95.7 0.0 EM
2018-11-21 PRO C:242 E:242 76.0 0.524 -65.6 149.0 76.0 0.524 0.0
PRO D:242 NA:NA DO NA DO DO DO NA NA NA
4zxb 5 P06213 95.48 0.0 X-RAY
2016-02-24 PRO E:242 E:242 54.0 0.372 -78.2 153.6 5.0 0.034 0.338 B:P01837:0.09
A:U5LP42:0.269
6sof 1 P06213 100.0 0.0 EM
2019-11-13 PRO A:242 A:242 84.0 0.579 -66.7 168.2 84.0 0.579 0.0
PRO C:242 C:242 56.0 0.386 -73.7 147.4 56.0 0.386 0.0
7qid 1 P06213 100.0 0.0 EM
2022-02-02 PRO A:242 A:242 102.0 0.703 -66.0 164.9 102.0 0.703 0.0
PRO C:242 C:242 44.0 0.303 -73.7 156.7 44.0 0.303 0.0
5kqv 5 P06213 99.83 0.0 X-RAY
2017-07-19 PRO E:242 E:242 52.0 0.359 -79.1 161.8 52.0 0.359 0.0
PRO F:242 F:242 52.0 0.359 -79.6 162.0 52.0 0.359 0.0
2hr7 1 P06213 99.59 0.0 X-RAY
2006-08-15 PRO A:242 A:242 55.0 0.379 -87.3 167.3 55.0 0.379 0.0 FUC
GOL
HOH
9.131
5.596
5.138
O
N
O
C6
O1
O
PRO B:242 B:242 52.0 0.359 -70.7 152.5 52.0 0.359 0.0 HOH
5.046
O
O
4oga 5 P06213 99.68 0.0 X-RAY
2014-08-27 PRO E:242 E:242 53.0 0.366 -85.6 159.7 5.0 0.034 0.332 C:None:0.255
D:None:0.076
4xss 2 P06213 99.68 0.0 X-RAY
2015-06-10 PRO B:242 E:242 53.0 0.366 -83.8 165.1 53.0 0.366 0.0
4xst 1 P06213 99.68 0.0 X-RAY
2015-06-10 PRO A:242 E:242 53.0 0.366 -85.4 162.4 53.0 0.366 0.0 NAG
9.954
O
O7
5j3h 4 P06213 99.68 0.0 X-RAY
2016-06-15 PRO D:242 E:242 53.0 0.366 -82.0 155.1 4.0 0.028 0.338 B:None:0.262
C:None:0.097
6vep 5 P06213 99.68 0.0 X-RAY
2020-06-03 PRO E:242 E:242 56.0 0.386 -79.0 155.3 6.0 0.041 0.345 D:None:0.09
C:None:0.262
HOH
9.666
CD
O
PRO K:242 K:242 57.0 0.393 -79.2 156.3 NA NA NA
PRO Q:242 Q:242 57.0 0.393 -80.9 155.8 NA NA NA
PRO W:242 W:242 56.0 0.386 -79.7 156.6 NA NA NA
6veq 3 P06213 99.68 0.0 X-RAY
2020-06-03 PRO C:242 E:242 59.0 0.407 -77.7 160.2 3.0 0.021 0.386 E:None:0.29
F:None:0.138
PRO G:242 K:242 58.0 0.4 -78.0 159.8 NA NA NA
7kd6 4 P06213 99.68 0.0 X-RAY
2021-10-13 PRO D:242 E:242 57.0 0.393 -82.4 151.8 7.0 0.048 0.345 B:None:0.262
C:None:0.09
HOH
8.361
O
O
PRO I:242 K:242 58.0 0.4 -81.9 153.3 NA NA NA
PRO N:242 Q:242 54.0 0.372 -84.4 155.6 NA NA NA
PRO S:242 W:242 57.0 0.393 -81.9 153.2 NA NA NA
3w11 5 P06213 99.68 0.0 X-RAY
2013-01-09 PRO E:242 E:242 56.0 0.386 -80.5 156.6 4.0 0.028 0.358 D:None:0.097
C:None:0.276
3w12 1 P06213 99.68 0.0 X-RAY
2013-01-09 PRO A:242 E:242 65.0 0.448 -80.9 152.5 3.0 0.021 0.427 B:None:0.317
C:None:0.145
3w13 1 P06213 99.68 0.0 X-RAY
2013-01-09 PRO A:242 E:242 65.0 0.448 -84.6 151.3 3.0 0.021 0.427 B:None:0.317
C:None:0.152

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06213-f1 1 P06213 100.0 0.0 PRO A:269 A:269 55.0 0.379 -66.5 145.0