Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 7184535 . G A CCDS12176.1:NM_000208.2:c.766Cgc>Tgc_NP_000199.2:p.256R>C Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7bw7 1 P06213 100.0 0.0 EM
 2021-04-14 ARG A:229 A:229 88.0 0.391 S -101.6 -30.4 88.0 0.391 0.0
ARG B:229 NA:NA DO NA DO DO DO NA NA NA
7bw8 1 P06213 100.0 0.0 EM
 2021-04-14 ARG A:229 A:229 101.0 0.449 S -90.5 -19.2 101.0 0.449 0.0
ARG B:229 NA:NA DO NA DO DO DO NA NA NA
7bwa 1 P06213 100.0 0.0 EM
 2021-04-14 ARG A:229 A:229 69.0 0.307 S -74.5 -64.0 69.0 0.307 0.0
ARG B:229 C:229 68.0 0.302 S -74.4 -64.1 NA NA NA
7pg0 1 P06213 99.13 0.0 EM
 2022-02-02 ARG A:256 A:229 64.0 0.284 S -71.8 -21.0 64.0 0.284 0.0
ARG B:256 B:229 30.0 0.133 S -93.7 -52.8 30.0 0.133 0.0
7pg2 1 P06213 99.13 0.0 EM
 2022-02-02 ARG A:256 A:229 69.0 0.307 S -89.3 -39.7 69.0 0.307 0.0
ARG B:256 B:229 40.0 0.178 S -73.0 -39.7 40.0 0.178 0.0
7pg3 1 P06213 99.13 0.0 EM
 2022-02-02 ARG A:256 A:229 44.0 0.196 S -71.1 -41.9 44.0 0.196 0.0
ARG B:256 B:229 86.0 0.382 S -59.1 -34.8 86.0 0.382 0.0
7pg4 1 P06213 99.13 0.0 EM
 2022-02-02 ARG A:256 A:229 87.0 0.387 S -63.2 -52.1 87.0 0.387 0.0
ARG B:256 B:229 71.0 0.316 S -90.0 -12.4 71.0 0.316 0.0
6pxv 1 P06213 98.6 0.0 EM
 2019-09-04 ARG A:229 A:229 113.0 0.502 S -75.3 -45.5 113.0 0.502 0.0
ARG B:229 C:229 110.0 0.489 S -75.3 -45.6 110.0 0.489 0.0
6pxw 1 P06213 98.6 0.0 EM
 2019-09-04 ARG A:229 A:229 113.0 0.502 S -75.3 -45.6 113.0 0.502 0.0
ARG B:229 B:229 111.0 0.493 S -75.4 -45.6 111.0 0.493 0.0
6ce7 1 P06213 99.89 0.0 EM
 2018-03-14 ARG A:229 B:229 109.0 0.484 S -63.2 -65.6 109.0 0.484 0.0
ARG B:229 A:229 98.0 0.436 S -71.8 -56.9 98.0 0.436 0.0
6ce9 1 P06213 98.6 0.0 EM
 2018-03-14 ARG A:229 A:229 102.0 0.453 S -71.3 -51.2 102.0 0.453 0.0 NAG
NAG
BMA
 3.053
5.171
8.553
 NE
NH2
NH2
 O6
O7
C1
ARG B:229 B:229 104.0 0.462 S -71.3 -51.3 104.0 0.462 0.0 NAG
NAG
BMA
 3.092
5.215
8.579
 NE
NH2
NH2
 O6
O5
C1
6ceb 1 P06213 98.6 0.0 EM
 2018-03-14 ARG A:229 A:229 109.0 0.484 S -73.8 -50.1 109.0 0.484 0.0 NAG
NAG
BMA
 2.724
4.878
8.435
 NH2
NH2
NH2
 O6
O5
C1
ARG B:229 B:229 107.0 0.476 S -67.9 -58.5 107.0 0.476 0.0 NAG
NAG
BMA
 2.862
5.035
8.232
 NE
NH2
NH2
 O6
O5
C1
6hn4 1 P06213,P03069 95.7 0.0 EM
 2018-11-21 ARG A:229 NA:NA DO NA DO DO DO NA NA NA
ARG B:229 F:229 112.0 0.498 S -71.3 -43.2 112.0 0.498 0.0 NAG
 2.557
 NE
 O6
6hn5 3 P06213,P03069 95.7 0.0 EM
 2018-11-21 ARG C:229 E:229 94.0 0.418 S -90.4 -26.5 94.0 0.418 0.0 NAG
NAG
 3.359
4.433
 NH2
NH2
 C6
C1
ARG D:229 NA:NA DO NA DO DO DO NA NA NA
4zxb 5 P06213 95.48 0.0 X-RAY
 2016-02-24 ARG E:229 E:229 86.0 0.382 S -71.4 -42.8 86.0 0.382 0.0 NAG
NAG
BMA
 3.350
4.630
9.376
 NE
NH2
NH2
 O6
O7
C1
6sof 1 P06213 100.0 0.0 EM
 2019-11-13 ARG A:229 A:229 91.0 0.404 S -101.6 -58.6 91.0 0.404 0.0
ARG C:229 C:229 85.0 0.378 S -69.1 -33.8 85.0 0.378 0.0
7qid 1 P06213 100.0 0.0 EM
 2022-02-02 ARG A:229 A:229 110.0 0.489 S -78.1 -13.0 110.0 0.489 0.0
ARG C:229 C:229 69.0 0.307 S -70.5 -27.5 69.0 0.307 0.0
5kqv 5 P06213 99.83 0.0 X-RAY
 2017-07-19 ARG E:229 E:229 97.0 0.431 S -72.7 -41.9 97.0 0.431 0.0
ARG F:229 F:229 97.0 0.431 S -72.6 -41.6 97.0 0.431 0.0
2hr7 1 P06213 99.59 0.0 X-RAY
 2006-08-15 ARG A:229 A:229 110.0 0.489 S -66.9 -45.5 110.0 0.489 0.0 NAG
NAG
BMA
MAN
GOL
GOL
GOL
HOH
 3.266
4.166
7.349
9.581
9.016
7.634
8.127
3.135
 NH1
NH2
NH2
O
CD
NH1
N
NH1
 C6
O5
C1
O6
O3
O1
O1
O
ARG B:229 B:229 99.0 0.44 S -74.3 -38.1 99.0 0.44 0.0 NAG
NAG
BMA
MAN
GOL
HOH
 3.727
6.278
9.630
8.633
8.108
2.624
 CG
NE
NE
O
N
NH1
 O6
O5
C1
C6
C1
O
4oga 5 P06213 99.68 0.0 X-RAY
 2014-08-27 ARG E:229 E:229 77.0 0.342 S -69.9 -45.6 77.0 0.342 0.0 NAG
NAG
BMA
MAN
 3.768
6.082
9.817
9.357
 CG
O
O
O
 O6
O6
C1
O6
4xss 2 P06213 99.68 0.0 X-RAY
 2015-06-10 ARG B:229 E:229 116.0 0.516 S -71.7 -46.6 116.0 0.516 0.0 NAG
 3.359
 NH1
 C6
4xst 1 P06213 99.68 0.0 X-RAY
 2015-06-10 ARG A:229 E:229 121.0 0.538 S -72.8 -44.6 121.0 0.538 0.0 NAG
 3.344
 NH1
 O6
5j3h 4 P06213 99.68 0.0 X-RAY
 2016-06-15 ARG D:229 E:229 81.0 0.36 S -72.9 -41.8 81.0 0.36 0.0 NAG
NAG
 3.447
4.584
 CG
O
 O6
O6
6vep 5 P06213 99.68 0.0 X-RAY
 2020-06-03 ARG E:229 E:229 95.0 0.422 S -70.3 -38.6 95.0 0.422 0.0 NAG
 3.402
 CG
 O6
ARG K:229 K:229 90.0 0.4 S -69.3 -39.3 NA NA NA
ARG Q:229 Q:229 96.0 0.427 S -70.9 -39.8 NA NA NA
ARG W:229 W:229 94.0 0.418 S -68.8 -40.7 NA NA NA
6veq 3 P06213 99.68 0.0 X-RAY
 2020-06-03 ARG C:229 E:229 100.0 0.444 S -66.9 -33.5 100.0 0.444 0.0 NAG
NAG
BMA
MAN
 3.493
3.715
8.903
9.399
 CG
NH2
NH2
O
 O6
O7
O5
C6
ARG G:229 K:229 103.0 0.458 S -67.2 -32.6 NA NA NA
7kd6 4 P06213 99.68 0.0 X-RAY
 2021-10-13 ARG D:229 E:229 92.0 0.409 S -61.8 -37.1 92.0 0.409 0.0 SO4
NAG
HOH
 9.769
3.381
4.054
 NH1
CG
O
 O3
O6
O
ARG I:229 K:229 90.0 0.4 S -62.9 -39.7 NA NA NA
ARG N:229 Q:229 90.0 0.4 S -65.7 -40.0 NA NA NA
ARG S:229 W:229 106.0 0.471 S -61.9 -41.8 NA NA NA
3w11 5 P06213 99.68 0.0 X-RAY
 2013-01-09 ARG E:229 E:229 92.0 0.409 S -62.0 -42.9 92.0 0.409 0.0 NAG
NAG
BMA
MAN
 3.561
5.852
9.724
9.351
 CG
O
O
O
 O6
O6
C1
O6
3w12 1 P06213 99.68 0.0 X-RAY
 2013-01-09 ARG A:229 E:229 84.0 0.373 S -86.6 -48.7 84.0 0.373 0.0 NAG
NAG
BMA
MAN
 3.609
5.488
9.518
9.097
 CG
NE
NH2
O
 O6
O6
C1
O6
3w13 1 P06213 99.68 0.0 X-RAY
 2013-01-09 ARG A:229 E:229 83.0 0.369 S -80.9 -47.7 83.0 0.369 0.0 NAG
NAG
BMA
MAN
 3.683
5.514
9.547
9.785
 CG
O
NH2
O
 O6
O6
O5
O6

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06213-f1 1 P06213 100.0 0.0 ARG A:256 A:256 103.0 0.458 S -65.8 -56.6