Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 7184548 . C A CCDS12176.1:NM_000208.2:c.753aaG>aaT_NP_000199.2:p.251K>N Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7bw7 1 P06213 100.0 0.0 EM
 2021-04-14 LYS A:224 A:224 73.0 0.365 S -132.0 30.2 73.0 0.365 0.0
LYS B:224 NA:NA DO NA DO DO DO NA NA NA
7bw8 1 P06213 100.0 0.0 EM
 2021-04-14 LYS A:224 A:224 100.0 0.5 S -130.4 38.1 100.0 0.5 0.0
LYS B:224 NA:NA DO NA DO DO DO NA NA NA
7bwa 1 P06213 100.0 0.0 EM
 2021-04-14 LYS A:224 A:224 102.0 0.51 T -104.1 38.9 102.0 0.51 0.0
LYS B:224 C:224 102.0 0.51 T -104.0 38.9 NA NA NA
7pg0 1 P06213 99.13 0.0 EM
 2022-02-02 LYS A:251 A:224 65.0 0.325 T -100.1 33.7 65.0 0.325 0.0
LYS B:251 B:224 97.0 0.485 G -111.4 6.9 97.0 0.485 0.0
7pg2 1 P06213 99.13 0.0 EM
 2022-02-02 LYS A:251 A:224 91.0 0.455 S -133.1 109.0 91.0 0.455 0.0
LYS B:251 B:224 94.0 0.47 S -121.3 110.8 94.0 0.47 0.0
7pg3 1 P06213 99.13 0.0 EM
 2022-02-02 LYS A:251 A:224 73.0 0.365 S -121.5 3.6 73.0 0.365 0.0
LYS B:251 B:224 102.0 0.51 G -89.9 7.7 102.0 0.51 0.0
7pg4 1 P06213 99.13 0.0 EM
 2022-02-02 LYS A:251 A:224 74.0 0.37 G -132.2 43.3 74.0 0.37 0.0
LYS B:251 B:224 93.0 0.465 T -92.1 -0.9 93.0 0.465 0.0
6pxv 1 P06213 98.6 0.0 EM
 2019-09-04 LYS A:224 A:224 56.0 0.28 G -118.9 21.0 56.0 0.28 0.0
LYS B:224 C:224 55.0 0.275 G -119.0 21.0 55.0 0.275 0.0
6pxw 1 P06213 98.6 0.0 EM
 2019-09-04 LYS A:224 A:224 55.0 0.275 G -118.9 21.0 55.0 0.275 0.0
LYS B:224 B:224 55.0 0.275 G -119.0 21.0 55.0 0.275 0.0
6ce7 1 P06213 99.89 0.0 EM
 2018-03-14 LYS A:224 B:224 58.0 0.29 -124.8 23.3 58.0 0.29 0.0
LYS B:224 A:224 88.0 0.44 T -97.4 31.3 88.0 0.44 0.0
6ce9 1 P06213 98.6 0.0 EM
 2018-03-14 LYS A:224 A:224 65.0 0.325 S -136.0 47.8 65.0 0.325 0.0 NAG
 8.924
 O
 C1
LYS B:224 B:224 66.0 0.33 S -136.0 47.9 66.0 0.33 0.0 NAG
 8.951
 O
 C1
6ceb 1 P06213 98.6 0.0 EM
 2018-03-14 LYS A:224 A:224 66.0 0.33 G -134.0 48.7 66.0 0.33 0.0 NAG
 8.861
 O
 C1
LYS B:224 B:224 67.0 0.335 S -134.3 48.6 67.0 0.335 0.0 NAG
 9.115
 O
 C1
6hn4 1 P06213,P03069 95.7 0.0 EM
 2018-11-21 LYS A:224 NA:NA DO NA DO DO DO NA NA NA
LYS B:224 F:224 69.0 0.345 S -117.9 19.1 69.0 0.345 0.0 NAG
 7.572
 O
 O5
6hn5 3 P06213,P03069 95.7 0.0 EM
 2018-11-21 LYS C:224 E:224 51.0 0.255 S -94.3 36.3 51.0 0.255 0.0 NAG
 7.156
 O
 O6
LYS D:224 NA:NA DO NA DO DO DO NA NA NA
4zxb 5 P06213 95.48 0.0 X-RAY
 2016-02-24 LYS E:224 E:224 47.0 0.235 S -117.9 18.0 47.0 0.235 0.0 NAG
 7.209
 O
 O5
6sof 1 P06213 100.0 0.0 EM
 2019-11-13 LYS A:224 A:224 97.0 0.485 S -114.2 29.5 97.0 0.485 0.0
LYS C:224 C:224 100.0 0.5 S -88.9 25.5 100.0 0.5 0.0
7qid 1 P06213 100.0 0.0 EM
 2022-02-02 LYS A:224 A:224 61.0 0.305 S -120.7 46.8 61.0 0.305 0.0
LYS C:224 C:224 84.0 0.42 T -68.4 -15.0 84.0 0.42 0.0
5kqv 5 P06213 99.83 0.0 X-RAY
 2017-07-19 LYS E:224 E:224 63.0 0.315 S -118.9 17.6 63.0 0.315 0.0
LYS F:224 F:224 62.0 0.31 S -120.0 18.0 62.0 0.31 0.0
2hr7 1 P06213 99.59 0.0 X-RAY
 2006-08-15 LYS A:224 A:224 68.0 0.34 S -120.5 16.9 68.0 0.34 0.0 NAG
NAG
GOL
GOL
HOH
 6.409
8.458
3.856
6.474
4.654
 O
O
N
CD
CB
 C6
C8
O3
C1
O
LYS B:224 B:224 77.0 0.385 S -121.9 18.9 77.0 0.385 0.0 NAG
NAG
SO4
GOL
HOH
 6.083
7.802
7.086
3.141
4.225
 O
O
N
N
CG
 C6
C8
O2
O3
O
4oga 5 P06213 99.68 0.0 X-RAY
 2014-08-27 LYS E:224 E:224 70.0 0.35 S -117.8 19.1 64.0 0.32 0.03 C:None:0.03
 NAG
 6.605
 O
 C6
4xss 2 P06213 99.68 0.0 X-RAY
 2015-06-10 LYS B:224 E:224 66.0 0.33 S -118.4 15.7 66.0 0.33 0.0 NAG
 6.860
 O
 C6
4xst 1 P06213 99.68 0.0 X-RAY
 2015-06-10 LYS A:224 E:224 82.0 0.41 S -117.5 16.6 82.0 0.41 0.0 NAG
 6.424
 O
 O6
5j3h 4 P06213 99.68 0.0 X-RAY
 2016-06-15 LYS D:224 E:224 75.0 0.375 S -117.5 17.1 73.0 0.365 0.01 B:None:0.01
 NAG
 6.379
 O
 O6
6vep 5 P06213 99.68 0.0 X-RAY
 2020-06-03 LYS E:224 E:224 64.0 0.32 S -111.4 12.8 59.0 0.295 0.025 C:None:0.025
 NAG
HOH
 5.923
7.401
 O
O
 O6
O
LYS K:224 K:224 64.0 0.32 S -112.0 12.5 NA NA NA
LYS Q:224 Q:224 63.0 0.315 S -111.7 12.3 NA NA NA
LYS W:224 W:224 62.0 0.31 S -111.5 12.3 NA NA NA
6veq 3 P06213 99.68 0.0 X-RAY
 2020-06-03 LYS C:224 E:224 70.0 0.35 G -108.6 14.5 68.0 0.34 0.01 E:None:0.01
 NAG
 6.933
 O
 O6
LYS G:224 K:224 70.0 0.35 G -108.3 13.3 NA NA NA
7kd6 4 P06213 99.68 0.0 X-RAY
 2021-10-13 LYS D:224 E:224 62.0 0.31 S -112.4 12.7 60.0 0.3 0.01 B:None:0.01
 NAG
SO4
HOH
 6.097
9.768
4.664
 O
N
CB
 O6
O3
O
LYS I:224 K:224 62.0 0.31 S -111.8 12.2 NA NA NA
LYS N:224 Q:224 66.0 0.33 S -117.2 9.2 NA NA NA
LYS S:224 W:224 63.0 0.315 S -111.1 15.4 NA NA NA
3w11 5 P06213 99.68 0.0 X-RAY
 2013-01-09 LYS E:224 E:224 78.0 0.39 S -115.5 20.6 74.0 0.37 0.02 C:None:0.02
 NAG
 7.141
 O
 O6
3w12 1 P06213 99.68 0.0 X-RAY
 2013-01-09 LYS A:224 E:224 81.0 0.405 S -113.4 25.0 78.0 0.39 0.015 B:None:0.015
 NAG
 7.431
 O
 O5
3w13 1 P06213 99.68 0.0 X-RAY
 2013-01-09 LYS A:224 E:224 80.0 0.4 S -107.9 19.0 75.0 0.375 0.025 B:None:0.025
 NAG
 7.300
 O
 O5

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06213-f1 1 P06213 100.0 0.0 LYS A:251 A:251 55.0 0.275 S -118.1 5.4