Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 7184582 . A C CCDS12176.1:NM_000208.2:c.719cTg>cGg_NP_000199.2:p.240L>R Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7bw7 1 P06213 100.0 0.0 EM
 2021-04-14 LEU A:213 A:213 14.0 0.082 -127.0 148.8 14.0 0.082 0.0
LEU B:213 NA:NA DO NA DO DO DO NA NA NA
7bw8 1 P06213 100.0 0.0 EM
 2021-04-14 LEU A:213 A:213 19.0 0.112 -139.8 166.6 19.0 0.112 0.0
LEU B:213 NA:NA DO NA DO DO DO NA NA NA
7bwa 1 P06213 100.0 0.0 EM
 2021-04-14 LEU A:213 A:213 34.0 0.2 -87.8 90.8 34.0 0.2 0.0
LEU B:213 C:213 34.0 0.2 -87.7 90.8 NA NA NA
7pg0 1 P06213 99.13 0.0 EM
 2022-02-02 LEU A:240 A:213 19.0 0.112 -113.1 125.3 19.0 0.112 0.0
LEU B:240 B:213 0.0 0.0 -121.1 136.4 0.0 0.0 0.0
7pg2 1 P06213 99.13 0.0 EM
 2022-02-02 LEU A:240 A:213 1.0 0.006 -131.3 156.4 1.0 0.006 0.0
LEU B:240 B:213 0.0 0.0 E -144.5 137.3 0.0 0.0 0.0
7pg3 1 P06213 99.13 0.0 EM
 2022-02-02 LEU A:240 A:213 15.0 0.088 E -139.2 141.4 15.0 0.088 0.0
LEU B:240 B:213 0.0 0.0 -153.0 142.9 0.0 0.0 0.0
7pg4 1 P06213 99.13 0.0 EM
 2022-02-02 LEU A:240 A:213 0.0 0.0 E -134.7 149.3 0.0 0.0 0.0
LEU B:240 B:213 0.0 0.0 S -157.9 107.5 0.0 0.0 0.0
6pxv 1 P06213 98.6 0.0 EM
 2019-09-04 LEU A:213 A:213 8.0 0.047 -153.4 112.7 8.0 0.047 0.0
LEU B:213 C:213 8.0 0.047 -153.3 112.8 8.0 0.047 0.0
6pxw 1 P06213 98.6 0.0 EM
 2019-09-04 LEU A:213 A:213 8.0 0.047 -153.4 112.7 8.0 0.047 0.0
LEU B:213 B:213 7.0 0.041 -153.4 112.8 7.0 0.041 0.0
6ce7 1 P06213 99.89 0.0 EM
 2018-03-14 LEU A:213 B:213 9.0 0.053 E -159.6 131.8 9.0 0.053 0.0
LEU B:213 A:213 14.0 0.082 -136.1 126.6 14.0 0.082 0.0
6ce9 1 P06213 98.6 0.0 EM
 2018-03-14 LEU A:213 A:213 10.0 0.059 E -152.6 119.6 10.0 0.059 0.0 NAG
NAG
NAG
 3.848
7.654
8.785
 CD1
CD1
O
 O5
O5
C8
LEU B:213 B:213 10.0 0.059 E -152.6 119.6 10.0 0.059 0.0 NAG
NAG
NAG
 3.877
7.698
8.777
 CD1
CD1
O
 O5
O5
C8
6ceb 1 P06213 98.6 0.0 EM
 2018-03-14 LEU A:213 A:213 9.0 0.053 E -156.8 125.0 9.0 0.053 0.0 NAG
NAG
NAG
 3.849
7.706
8.805
 CD1
CD1
O
 O5
O5
C8
LEU B:213 B:213 10.0 0.059 E -154.9 123.5 10.0 0.059 0.0 NAG
NAG
NAG
 3.607
7.511
8.643
 CD1
CD1
O
 O5
O5
C8
6hn4 1 P06213,P03069 95.7 0.0 EM
 2018-11-21 LEU A:213 NA:NA DO NA DO DO DO NA NA NA
LEU B:213 F:213 5.0 0.029 -135.8 119.9 5.0 0.029 0.0 NAG
NAG
 3.455
8.728
 CD1
O
 O5
C1
6hn5 3 P06213,P03069 95.7 0.0 EM
 2018-11-21 LEU C:213 E:213 5.0 0.029 E -135.6 136.3 5.0 0.029 0.0 NAG
NAG
NAG
 3.262
7.764
9.339
 CD1
CD1
O
 O5
C1
C1
LEU D:213 NA:NA DO NA DO DO DO NA NA NA
4zxb 5 P06213 95.48 0.0 X-RAY
 2016-02-24 LEU E:213 E:213 5.0 0.029 -135.5 118.8 5.0 0.029 0.0 NAG
NAG
NAG
 3.406
6.863
8.749
 CD1
CD2
O
 O5
O6
C1
6sof 1 P06213 100.0 0.0 EM
 2019-11-13 LEU A:213 A:213 33.0 0.194 E -157.3 157.1 33.0 0.194 0.0
LEU C:213 C:213 10.0 0.059 E -164.5 153.4 10.0 0.059 0.0
7qid 1 P06213 100.0 0.0 EM
 2022-02-02 LEU A:213 A:213 49.0 0.288 S -134.5 -9.4 49.0 0.288 0.0
LEU C:213 C:213 3.0 0.018 -161.6 147.5 3.0 0.018 0.0
5kqv 5 P06213 99.83 0.0 X-RAY
 2017-07-19 LEU E:213 E:213 5.0 0.029 -134.1 119.7 5.0 0.029 0.0
LEU F:213 F:213 4.0 0.024 -134.2 119.8 4.0 0.024 0.0
2hr7 1 P06213 99.59 0.0 X-RAY
 2006-08-15 LEU A:213 A:213 5.0 0.029 -130.8 114.6 5.0 0.029 0.0 NAG
NAG
NAG
GOL
GOL
HOH
 3.408
7.350
8.583
7.813
7.833
3.615
 CD1
CD1
O
CD1
N
CD1
 O5
O5
C1
O3
O1
O
LEU B:213 B:213 3.0 0.018 -136.5 123.2 3.0 0.018 0.0 NAG
NAG
NAG
GOL
HOH
 3.590
7.499
8.587
7.996
3.835
 CD1
CD1
O
N
CD1
 O5
O5
C1
O3
O
4oga 5 P06213 99.68 0.0 X-RAY
 2014-08-27 LEU E:213 E:213 4.0 0.024 -132.2 114.1 4.0 0.024 0.0 NAG
NAG
NAG
 3.430
7.378
8.765
 CD1
CD1
O
 O5
O5
C1
4xss 2 P06213 99.68 0.0 X-RAY
 2015-06-10 LEU B:213 E:213 4.0 0.024 -139.7 118.4 4.0 0.024 0.0 NAG
NAG
 3.268
8.695
 CD1
O
 O5
C1
4xst 1 P06213 99.68 0.0 X-RAY
 2015-06-10 LEU A:213 E:213 4.0 0.024 -133.7 116.2 4.0 0.024 0.0 NAG
NAG
 8.774
3.203
 O
CD1
 C1
O6
5j3h 4 P06213 99.68 0.0 X-RAY
 2016-06-15 LEU D:213 E:213 4.0 0.024 -134.7 119.6 4.0 0.024 0.0 NAG
NAG
NAG
 3.313
7.348
8.766
 CD1
CD1
O
 O5
O5
C1
6vep 5 P06213 99.68 0.0 X-RAY
 2020-06-03 LEU E:213 E:213 4.0 0.024 E -139.5 125.9 4.0 0.024 0.0 NAG
NAG
HOH
 3.540
8.705
9.559
 CD1
O
CD1
 O5
C1
O
LEU K:213 K:213 4.0 0.024 E -139.3 126.0 NA NA NA
LEU Q:213 Q:213 4.0 0.024 E -139.2 127.0 NA NA NA
LEU W:213 W:213 4.0 0.024 E -140.3 126.0 NA NA NA
6veq 3 P06213 99.68 0.0 X-RAY
 2020-06-03 LEU C:213 E:213 7.0 0.041 -157.9 106.4 7.0 0.041 0.0 NAG
NAG
NAG
 3.399
7.192
9.147
 CD1
CD1
O
 O5
O5
C1
LEU G:213 K:213 4.0 0.024 -158.1 107.1 NA NA NA
7kd6 4 P06213 99.68 0.0 X-RAY
 2021-10-13 LEU D:213 E:213 5.0 0.029 -143.2 125.8 5.0 0.029 0.0 NAG
NAG
HOH
 8.671
3.531
5.396
 O
CD1
CD1
 C1
O6
O
LEU I:213 K:213 5.0 0.029 E -138.0 126.8 NA NA NA
LEU N:213 Q:213 5.0 0.029 -140.1 123.2 NA NA NA
LEU S:213 W:213 6.0 0.035 E -139.0 123.8 NA NA NA
3w11 5 P06213 99.68 0.0 X-RAY
 2013-01-09 LEU E:213 E:213 4.0 0.024 -101.8 -87.7 4.0 0.024 0.0 NAG
NAG
NAG
 3.598
7.404
9.779
 CD1
CD1
C
 O5
O5
C1
3w12 1 P06213 99.68 0.0 X-RAY
 2013-01-09 LEU A:213 E:213 6.0 0.035 -95.1 -86.7 6.0 0.035 0.0 NAG
NAG
NAG
 3.673
7.259
9.940
 CD1
CD1
C
 O5
O5
C1
3w13 1 P06213 99.68 0.0 X-RAY
 2013-01-09 LEU A:213 E:213 6.0 0.035 -99.4 -81.8 6.0 0.035 0.0 NAG
NAG
NAG
 3.650
7.235
9.933
 CD1
CD1
C
 O5
O5
C1

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06213-f1 1 P06213 100.0 0.0 LEU A:240 A:240 4.0 0.024 E -132.9 125.0