Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 7184589 . C A CCDS12176.1:NM_000208.2:c.712Gag>Tag_NP_000199.2:p.238E>* Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7bw7 1 P06213 100.0 0.0 EM
 2021-04-14 GLU A:211 A:211 29.0 0.153 T -108.9 32.6 29.0 0.153 0.0
GLU B:211 NA:NA DO NA DO DO DO NA NA NA
7bw8 1 P06213 100.0 0.0 EM
 2021-04-14 GLU A:211 A:211 21.0 0.111 T -140.8 47.0 21.0 0.111 0.0
GLU B:211 NA:NA DO NA DO DO DO NA NA NA
7bwa 1 P06213 100.0 0.0 EM
 2021-04-14 GLU A:211 A:211 25.0 0.132 T -85.0 23.6 25.0 0.132 0.0
GLU B:211 C:211 25.0 0.132 T -85.0 23.6 NA NA NA
7pg0 1 P06213 99.13 0.0 EM
 2022-02-02 GLU A:238 A:211 17.0 0.089 T -138.4 8.7 17.0 0.089 0.0
GLU B:238 B:211 37.0 0.195 S -58.5 -46.9 37.0 0.195 0.0
7pg2 1 P06213 99.13 0.0 EM
 2022-02-02 GLU A:238 A:211 38.0 0.2 T -97.1 8.2 38.0 0.2 0.0
GLU B:238 B:211 18.0 0.095 S -78.6 -14.4 18.0 0.095 0.0
7pg3 1 P06213 99.13 0.0 EM
 2022-02-02 GLU A:238 A:211 45.0 0.237 T -124.8 23.4 45.0 0.237 0.0
GLU B:238 B:211 36.0 0.189 T -111.6 -19.4 36.0 0.189 0.0
7pg4 1 P06213 99.13 0.0 EM
 2022-02-02 GLU A:238 A:211 7.0 0.037 T -88.1 21.1 7.0 0.037 0.0
GLU B:238 B:211 99.0 0.521 S -124.1 42.7 99.0 0.521 0.0
6pxv 1 P06213 98.6 0.0 EM
 2019-09-04 GLU A:211 A:211 17.0 0.089 T -114.6 4.3 17.0 0.089 0.0
GLU B:211 C:211 16.0 0.084 T -114.6 4.2 16.0 0.084 0.0
6pxw 1 P06213 98.6 0.0 EM
 2019-09-04 GLU A:211 A:211 18.0 0.095 T -114.6 4.3 18.0 0.095 0.0
GLU B:211 B:211 16.0 0.084 T -114.6 4.3 16.0 0.084 0.0
6ce7 1 P06213 99.89 0.0 EM
 2018-03-14 GLU A:211 B:211 19.0 0.1 T -125.1 0.8 19.0 0.1 0.0
GLU B:211 A:211 9.0 0.047 T -96.5 -1.3 9.0 0.047 0.0
6ce9 1 P06213 98.6 0.0 EM
 2018-03-14 GLU A:211 A:211 18.0 0.095 T -114.0 -2.7 18.0 0.095 0.0 NAG
 8.867
 O
 C6
GLU B:211 B:211 18.0 0.095 T -114.0 -2.6 18.0 0.095 0.0 NAG
 8.917
 O
 C6
6ceb 1 P06213 98.6 0.0 EM
 2018-03-14 GLU A:211 A:211 15.0 0.079 T -118.8 -0.9 15.0 0.079 0.0 NAG
 8.861
 O
 C6
GLU B:211 B:211 16.0 0.084 T -115.6 -3.4 16.0 0.084 0.0 NAG
 8.537
 O
 C6
6hn4 1 P06213,P03069 95.7 0.0 EM
 2018-11-21 GLU A:211 NA:NA DO NA DO DO DO NA NA NA
GLU B:211 F:211 30.0 0.158 T -92.1 -6.1 30.0 0.158 0.0 NAG
 8.382
 O
 O6
6hn5 3 P06213,P03069 95.7 0.0 EM
 2018-11-21 GLU C:211 E:211 32.0 0.168 T -85.1 15.3 32.0 0.168 0.0 NAG
 8.191
 O
 O6
GLU D:211 NA:NA DO NA DO DO DO NA NA NA
4zxb 5 P06213 95.48 0.0 X-RAY
 2016-02-24 GLU E:211 E:211 25.0 0.132 T -91.8 -5.8 14.0 0.074 0.058 A:U5LP42:0.058
 NAG
 8.269
 O
 C6
6sof 1 P06213 100.0 0.0 EM
 2019-11-13 GLU A:211 A:211 13.0 0.068 S -93.3 -10.1 13.0 0.068 0.0
GLU C:211 C:211 31.0 0.163 T -140.6 -8.4 31.0 0.163 0.0
7qid 1 P06213 100.0 0.0 EM
 2022-02-02 GLU A:211 A:211 33.0 0.174 T 75.9 -5.0 33.0 0.174 0.0
GLU C:211 C:211 32.0 0.168 T -75.7 -27.8 32.0 0.168 0.0
5kqv 5 P06213 99.83 0.0 X-RAY
 2017-07-19 GLU E:211 E:211 25.0 0.132 T -88.4 -9.2 25.0 0.132 0.0
GLU F:211 F:211 23.0 0.121 T -88.6 -9.5 23.0 0.121 0.0
2hr7 1 P06213 99.59 0.0 X-RAY
 2006-08-15 GLU A:211 A:211 26.0 0.137 T -87.8 -11.0 26.0 0.137 0.0 NAG
GOL
GOL
HOH
 7.808
3.831
6.862
2.650
 O
OE2
O
OE1
 O6
O3
O3
O
GLU B:211 B:211 19.0 0.1 T -89.1 -6.3 19.0 0.1 0.0 NAG
SO4
GOL
HOH
 8.187
9.889
7.229
2.679
 O
CG
O
OE1
 O6
O1
O3
O
4oga 5 P06213 99.68 0.0 X-RAY
 2014-08-27 GLU E:211 E:211 21.0 0.111 T -89.7 -7.9 10.0 0.053 0.058 C:None:0.058
 NAG
NAG
 7.809
9.616
 O
OE2
 O6
O6
4xss 2 P06213 99.68 0.0 X-RAY
 2015-06-10 GLU B:211 E:211 27.0 0.142 T -87.3 -11.6 27.0 0.142 0.0 NAG
 8.133
 O
 C6
4xst 1 P06213 99.68 0.0 X-RAY
 2015-06-10 GLU A:211 E:211 25.0 0.132 T -85.4 -12.6 25.0 0.132 0.0 NAG
 7.664
 O
 O6
5j3h 4 P06213 99.68 0.0 X-RAY
 2016-06-15 GLU D:211 E:211 17.0 0.089 T -91.6 -8.0 10.0 0.053 0.036 B:None:0.037
 NAG
NAG
 8.268
8.946
 O
OE1
 O6
O6
6vep 5 P06213 99.68 0.0 X-RAY
 2020-06-03 GLU E:211 E:211 18.0 0.095 T -92.3 -9.2 11.0 0.058 0.037 C:None:0.037
 NAG
 7.711
 O
 O6
GLU K:211 K:211 17.0 0.089 T -93.8 -7.5 NA NA NA
GLU Q:211 Q:211 19.0 0.1 T -93.1 -8.0 NA NA NA
GLU W:211 W:211 18.0 0.095 T -93.7 -8.3 NA NA NA
6veq 3 P06213 99.68 0.0 X-RAY
 2020-06-03 GLU C:211 E:211 22.0 0.116 T -102.9 -8.2 12.0 0.063 0.053 E:None:0.053
 NAG
NAG
 7.687
9.836
 O
OE2
 O6
O7
GLU G:211 K:211 22.0 0.116 T -103.9 -8.1 NA NA NA
7kd6 4 P06213 99.68 0.0 X-RAY
 2021-10-13 GLU D:211 E:211 16.0 0.084 T -98.3 -8.2 9.0 0.047 0.037 B:None:0.037
 SO4
NAG
HOH
 5.725
7.716
4.475
 CG
O
OE2
 O3
O6
O
GLU I:211 K:211 18.0 0.095 T -91.8 -12.6 NA NA NA
GLU N:211 Q:211 18.0 0.095 T -88.9 -8.3 NA NA NA
GLU S:211 W:211 18.0 0.095 T -95.5 -8.3 NA NA NA
3w11 5 P06213 99.68 0.0 X-RAY
 2013-01-09 GLU E:211 E:211 24.0 0.126 T -91.1 -4.5 11.0 0.058 0.068 C:None:0.068
 NAG
NAG
 7.828
9.296
 O
OE2
 O6
O6
3w12 1 P06213 99.68 0.0 X-RAY
 2013-01-09 GLU A:211 E:211 23.0 0.121 T -100.6 -2.4 11.0 0.058 0.063 B:None:0.063
 NAG
NAG
 7.991
8.545
 O
OE2
 O6
O6
3w13 1 P06213 99.68 0.0 X-RAY
 2013-01-09 GLU A:211 E:211 26.0 0.137 T -102.3 -0.8 13.0 0.068 0.069 B:None:0.068
 NAG
NAG
 7.986
8.885
 O
OE2
 O6
O6

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06213-f1 1 P06213 100.0 0.0 GLU A:238 A:238 26.0 0.137 T -90.1 -7.8