Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 7267401 . C A CCDS12176.1:NM_000208.2:c.607Ggg>Tgg_NP_000199.2:p.203G>W Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7bw7 1 P06213 100.0 0.0 EM
 2021-04-14 GLY A:176 NA:NA DO NA DO DO DO NA NA NA
GLY B:176 NA:NA DO NA DO DO DO NA NA NA
7bw8 1 P06213 100.0 0.0 EM
 2021-04-14 GLY A:176 NA:NA DO NA DO DO DO NA NA NA
GLY B:176 NA:NA DO NA DO DO DO NA NA NA
7bwa 1 P06213 100.0 0.0 EM
 2021-04-14 GLY A:176 NA:NA DO NA DO DO DO NA NA NA
GLY B:176 NA:NA DO NA DO DO DO NA NA NA
7pg0 1 P06213 99.13 0.0 EM
 2022-02-02 GLY A:203 A:176 78.0 1.0 S -61.0 -41.2 78.0 1.0 0.0
GLY B:203 NA:NA DO NA DO DO DO NA NA NA
7pg2 1 P06213 99.13 0.0 EM
 2022-02-02 GLY A:203 A:176 47.0 0.627 S 102.7 14.1 47.0 0.627 0.0
GLY B:203 NA:NA DO NA DO DO DO NA NA NA
7pg3 1 P06213 99.13 0.0 EM
 2022-02-02 GLY A:203 A:176 51.0 0.68 S 107.6 32.6 51.0 0.68 0.0
GLY B:203 NA:NA DO NA DO DO DO NA NA NA
7pg4 1 P06213 99.13 0.0 EM
 2022-02-02 GLY A:203 A:176 54.0 0.72 S 75.5 21.0 54.0 0.72 0.0
GLY B:203 NA:NA DO NA DO DO DO NA NA NA
6pxv 1 P06213 98.6 0.0 EM
 2019-09-04 GLY A:176 A:176 71.0 0.947 S -145.6 7.6 71.0 0.947 0.0
GLY B:176 C:176 71.0 0.947 S -145.5 7.6 71.0 0.947 0.0
6pxw 1 P06213 98.6 0.0 EM
 2019-09-04 GLY A:176 A:176 72.0 0.96 S -145.6 7.6 72.0 0.96 0.0
GLY B:176 B:176 71.0 0.947 S -145.5 7.5 71.0 0.947 0.0
6ce7 1 P06213 99.89 0.0 EM
 2018-03-14 GLY A:176 NA:NA DO NA DO DO DO NA NA NA
GLY B:176 NA:NA DO NA DO DO DO NA NA NA
6ce9 1 P06213 98.6 0.0 EM
 2018-03-14 GLY A:176 A:176 74.0 0.987 S -116.3 -34.5 74.0 0.987 0.0
GLY B:176 B:176 72.0 0.96 S -116.3 -34.6 72.0 0.96 0.0
6ceb 1 P06213 98.6 0.0 EM
 2018-03-14 GLY A:176 A:176 75.0 1.0 S -117.9 -33.7 75.0 1.0 0.0
GLY B:176 B:176 74.0 0.987 S -117.8 -34.5 74.0 0.987 0.0
6hn4 1 P06213,P03069 95.7 0.0 EM
 2018-11-21 GLY A:176 NA:NA DO NA DO DO DO NA NA NA
GLY B:176 F:176 68.0 0.907 S 117.6 -41.7 68.0 0.907 0.0 NAG
 5.702
 O
 O4
6hn5 3 P06213,P03069 95.7 0.0 EM
 2018-11-21 GLY C:176 E:176 79.0 1.0 S -76.2 -2.2 79.0 1.0 0.0
GLY D:176 NA:NA DO NA DO DO DO NA NA NA
4zxb 5 P06213 95.48 0.0 X-RAY
 2016-02-24 GLY E:176 NA:NA DO NA DO DO DO NA NA NA
6sof 1 P06213 100.0 0.0 EM
 2019-11-13 GLY A:176 A:176 63.0 0.84 S 95.5 -98.2 63.0 0.84 0.0
GLY C:176 C:176 49.0 0.653 S 145.9 -7.7 49.0 0.653 0.0
7qid 1 P06213 100.0 0.0 EM
 2022-02-02 GLY A:176 A:176 70.0 0.933 T 98.9 -11.8 70.0 0.933 0.0
GLY C:176 C:176 51.0 0.68 S 86.2 -47.5 51.0 0.68 0.0
5kqv 5 P06213 99.83 0.0 X-RAY
 2017-07-19 GLY E:176 E:176 60.0 0.8 S -117.0 -14.0 60.0 0.8 0.0
GLY F:176 F:176 60.0 0.8 S -117.3 -13.6 60.0 0.8 0.0
2hr7 1 P06213 99.59 0.0 X-RAY
 2006-08-15 GLY A:176 A:176 75.0 1.0 T -110.4 17.5 53.0 0.707 0.293 B:P06213:0.293
 HOH
 4.653
 O
 O
GLY B:176 B:176 63.0 0.84 S -114.7 -17.5 8.0 0.107 0.733 A:P06213:0.733
 NAG
FUC
HOH
 9.696
7.338
7.887
 O
C
O
 O5
C6
O
4oga 5 P06213 99.68 0.0 X-RAY
 2014-08-27 GLY E:176 E:176 78.0 1.0 S -115.9 14.2 78.0 1.0 0.0
4xss 2 P06213 99.68 0.0 X-RAY
 2015-06-10 GLY B:176 E:176 77.0 1.0 T 77.3 -9.8 77.0 1.0 0.0 SO4
 8.386
 N
 O3
4xst 1 P06213 99.68 0.0 X-RAY
 2015-06-10 GLY A:176 E:176 65.0 0.867 T -119.1 16.8 65.0 0.867 0.0
5j3h 4 P06213 99.68 0.0 X-RAY
 2016-06-15 GLY D:176 NA:NA DO NA DO DO DO NA NA NA
6vep 5 P06213 99.68 0.0 X-RAY
 2020-06-03 GLY E:176 E:176 58.0 0.773 T 85.8 -17.1 58.0 0.773 0.0
GLY K:176 K:176 68.0 0.907 T 84.4 -15.5 NA NA NA
GLY Q:176 Q:176 110.0 1.0 360.0 -16.7 NA NA NA
GLY W:176 W:176 66.0 0.88 T 85.7 -16.8 NA NA NA
6veq 3 P06213 99.68 0.0 X-RAY
 2020-06-03 GLY C:176 E:176 69.0 0.92 S -146.6 29.6 69.0 0.92 0.0
GLY G:176 K:176 61.0 0.813 S -148.1 27.0 NA NA NA
7kd6 4 P06213 99.68 0.0 X-RAY
 2021-10-13 GLY D:176 NA:NA DO NA DO DO DO NA NA NA
GLY I:176 NA:NA DO NA DO DO DO NA NA NA
GLY N:176 Q:176 65.0 0.867 S 66.7 43.8 NA NA NA
GLY S:176 W:176 106.0 1.0 360.0 -94.0 NA NA NA
3w11 5 P06213 99.68 0.0 X-RAY
 2013-01-09 GLY E:176 E:176 74.0 0.987 S -103.9 -20.0 74.0 0.987 0.0
3w12 1 P06213 99.68 0.0 X-RAY
 2013-01-09 GLY A:176 E:176 81.0 1.0 S -118.7 21.7 81.0 1.0 0.0
3w13 1 P06213 99.68 0.0 X-RAY
 2013-01-09 GLY A:176 E:176 78.0 1.0 S -119.2 24.8 78.0 1.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06213-f1 1 P06213 100.0 0.0 GLY A:203 A:203 60.0 0.8 T 81.4 -5.8