Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 7267416 . C A CCDS12176.1:NM_000208.2:c.592Gcc>Tcc_NP_000199.2:p.198A>S Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7bw7 1 P06213 100.0 0.0 EM
 2021-04-14 ALA A:171 NA:NA DO NA DO DO DO NA NA NA
ALA B:171 NA:NA DO NA DO DO DO NA NA NA
7bw8 1 P06213 100.0 0.0 EM
 2021-04-14 ALA A:171 NA:NA DO NA DO DO DO NA NA NA
ALA B:171 NA:NA DO NA DO DO DO NA NA NA
7bwa 1 P06213 100.0 0.0 EM
 2021-04-14 ALA A:171 NA:NA DO NA DO DO DO NA NA NA
ALA B:171 NA:NA DO NA DO DO DO NA NA NA
7pg0 1 P06213 99.13 0.0 EM
 2022-02-02 ALA A:198 A:171 37.0 0.322 54.9 -157.5 37.0 0.322 0.0
ALA B:198 B:171 86.0 0.748 -70.6 149.3 86.0 0.748 0.0
7pg2 1 P06213 99.13 0.0 EM
 2022-02-02 ALA A:198 A:171 39.0 0.339 55.0 61.2 39.0 0.339 0.0
ALA B:198 B:171 10.0 0.087 -59.2 146.9 10.0 0.087 0.0
7pg3 1 P06213 99.13 0.0 EM
 2022-02-02 ALA A:198 A:171 24.0 0.209 65.2 40.9 24.0 0.209 0.0
ALA B:198 B:171 43.0 0.374 -138.0 20.5 43.0 0.374 0.0
7pg4 1 P06213 99.13 0.0 EM
 2022-02-02 ALA A:198 A:171 35.0 0.304 64.2 41.0 35.0 0.304 0.0
ALA B:198 B:171 81.0 0.704 -61.1 140.9 81.0 0.704 0.0
6pxv 1 P06213 98.6 0.0 EM
 2019-09-04 ALA A:171 A:171 54.0 0.47 E -143.8 105.1 54.0 0.47 0.0
ALA B:171 C:171 56.0 0.487 E -143.8 105.1 56.0 0.487 0.0
6pxw 1 P06213 98.6 0.0 EM
 2019-09-04 ALA A:171 A:171 54.0 0.47 E -143.8 105.2 54.0 0.47 0.0
ALA B:171 B:171 55.0 0.478 E -143.8 105.1 55.0 0.478 0.0
6ce7 1 P06213 99.89 0.0 EM
 2018-03-14 ALA A:171 B:171 55.0 0.478 B -120.1 140.3 55.0 0.478 0.0
ALA B:171 NA:NA DO NA DO DO DO NA NA NA
6ce9 1 P06213 98.6 0.0 EM
 2018-03-14 ALA A:171 A:171 52.0 0.452 E -94.7 94.6 52.0 0.452 0.0
ALA B:171 B:171 51.0 0.443 E -94.7 94.6 51.0 0.443 0.0
6ceb 1 P06213 98.6 0.0 EM
 2018-03-14 ALA A:171 A:171 52.0 0.452 E -97.6 89.0 52.0 0.452 0.0
ALA B:171 B:171 52.0 0.452 E -97.5 95.0 52.0 0.452 0.0
6hn4 1 P06213,P03069 95.7 0.0 EM
 2018-11-21 ALA A:171 NA:NA DO NA DO DO DO NA NA NA
ALA B:171 F:171 37.0 0.322 E -124.5 140.8 37.0 0.322 0.0 NAG
 9.606
 CB
 O4
6hn5 3 P06213,P03069 95.7 0.0 EM
 2018-11-21 ALA C:171 E:171 49.0 0.426 57.7 67.4 49.0 0.426 0.0
ALA D:171 NA:NA DO NA DO DO DO NA NA NA
4zxb 5 P06213 95.48 0.0 X-RAY
 2016-02-24 ALA E:171 E:171 28.0 0.243 B -120.3 141.7 28.0 0.243 0.0
6sof 1 P06213 100.0 0.0 EM
 2019-11-13 ALA A:171 A:171 62.0 0.539 E -81.1 64.7 62.0 0.539 0.0
ALA C:171 C:171 33.0 0.287 -81.4 154.8 33.0 0.287 0.0
7qid 1 P06213 100.0 0.0 EM
 2022-02-02 ALA A:171 A:171 60.0 0.522 E -72.5 95.4 60.0 0.522 0.0
ALA C:171 C:171 42.0 0.365 -95.2 106.3 42.0 0.365 0.0
5kqv 5 P06213 99.83 0.0 X-RAY
 2017-07-19 ALA E:171 E:171 53.0 0.461 -117.8 137.9 53.0 0.461 0.0
ALA F:171 F:171 54.0 0.47 E -120.8 136.0 54.0 0.47 0.0
2hr7 1 P06213 99.59 0.0 X-RAY
 2006-08-15 ALA A:171 A:171 37.0 0.322 -58.5 155.4 35.0 0.304 0.018 B:P06213:0.017
 GOL
HOH
 4.563
6.429
 O
CB
 O2
O
ALA B:171 B:171 52.0 0.452 E -125.9 135.4 28.0 0.243 0.209 A:P06213:0.209
 SO4
HOH
 5.942
4.799
 CB
O
 O3
O
4oga 5 P06213 99.68 0.0 X-RAY
 2014-08-27 ALA E:171 E:171 46.0 0.4 -51.4 136.3 46.0 0.4 0.0
4xss 2 P06213 99.68 0.0 X-RAY
 2015-06-10 ALA B:171 E:171 34.0 0.296 E -106.4 139.0 34.0 0.296 0.0 SO4
 4.290
 O
 O2
4xst 1 P06213 99.68 0.0 X-RAY
 2015-06-10 ALA A:171 E:171 47.0 0.409 -57.3 151.5 47.0 0.409 0.0 SO4
 4.522
 O
 O2
5j3h 4 P06213 99.68 0.0 X-RAY
 2016-06-15 ALA D:171 E:171 56.0 0.487 E -123.9 137.0 56.0 0.487 0.0
6vep 5 P06213 99.68 0.0 X-RAY
 2020-06-03 ALA E:171 E:171 57.0 0.496 E -121.8 128.4 57.0 0.496 0.0
ALA K:171 K:171 52.0 0.452 E -123.6 131.5 NA NA NA
ALA Q:171 Q:171 51.0 0.443 E -122.2 129.8 NA NA NA
ALA W:171 W:171 51.0 0.443 E -123.0 131.0 NA NA NA
6veq 3 P06213 99.68 0.0 X-RAY
 2020-06-03 ALA C:171 E:171 37.0 0.322 E -123.7 129.1 37.0 0.322 0.0
ALA G:171 K:171 51.0 0.443 E -123.0 128.5 NA NA NA
7kd6 4 P06213 99.68 0.0 X-RAY
 2021-10-13 ALA D:171 E:171 47.0 0.409 E -122.9 139.4 47.0 0.409 0.0
ALA I:171 K:171 47.0 0.409 E -119.3 138.6 NA NA NA
ALA N:171 Q:171 49.0 0.426 E -111.6 136.5 NA NA NA
ALA S:171 W:171 44.0 0.383 E -118.3 137.9 NA NA NA
3w11 5 P06213 99.68 0.0 X-RAY
 2013-01-09 ALA E:171 E:171 51.0 0.443 E -94.5 149.2 51.0 0.443 0.0
3w12 1 P06213 99.68 0.0 X-RAY
 2013-01-09 ALA A:171 E:171 42.0 0.365 E -116.3 136.2 42.0 0.365 0.0
3w13 1 P06213 99.68 0.0 X-RAY
 2013-01-09 ALA A:171 E:171 45.0 0.391 E -123.0 140.2 45.0 0.391 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06213-f1 1 P06213 100.0 0.0 ALA A:198 A:198 28.0 0.243 E -119.3 140.7