Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 7267473 . T A CCDS12176.1:NM_000208.2:c.535Aac>Tac_NP_000199.2:p.179N>Y Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7bw7 1 P06213 100.0 0.0 EM
 2021-04-14 ASN A:152 A:152 125.0 0.781 -64.4 360.0 125.0 0.781 0.0
ASN B:152 NA:NA DO NA DO DO DO NA NA NA
7bw8 1 P06213 100.0 0.0 EM
 2021-04-14 ASN A:152 A:152 147.0 0.919 -63.5 360.0 147.0 0.919 0.0
ASN B:152 NA:NA DO NA DO DO DO NA NA NA
7bwa 1 P06213 100.0 0.0 EM
 2021-04-14 ASN A:152 A:152 125.0 0.781 -66.7 360.0 125.0 0.781 0.0
ASN B:152 C:152 125.0 0.781 -66.7 360.0 NA NA NA
7pg0 1 P06213 99.13 0.0 EM
 2022-02-02 ASN A:179 A:152 91.0 0.569 S -79.5 -178.8 91.0 0.569 0.0
ASN B:179 B:152 94.0 0.588 T -75.7 -10.6 94.0 0.588 0.0
7pg2 1 P06213 99.13 0.0 EM
 2022-02-02 ASN A:179 A:152 103.0 0.644 S -127.4 -171.8 72.0 0.45 0.194 G:P01308:0.194
ASN B:179 B:152 99.0 0.619 T -118.7 -8.0 99.0 0.619 0.0
7pg3 1 P06213 99.13 0.0 EM
 2022-02-02 ASN A:179 A:152 104.0 0.65 S -119.7 -174.0 77.0 0.481 0.169 G:P01308:0.169
ASN B:179 B:152 100.0 0.625 T -104.3 5.9 60.0 0.375 0.25 A:P06213:0.25
7pg4 1 P06213 99.13 0.0 EM
 2022-02-02 ASN A:179 A:152 130.0 0.812 G -98.3 11.6 122.0 0.762 0.05 E:P01308:0.05
ASN B:179 B:152 146.0 0.912 T -116.2 13.0 146.0 0.912 0.0
6pxv 1 P06213 98.6 0.0 EM
 2019-09-04 ASN A:152 A:152 115.0 0.719 H -74.3 -43.7 95.0 0.594 0.125 E:A6XGL2:0.125
ASN B:152 C:152 115.0 0.719 H -74.2 -43.8 92.0 0.575 0.144 F:A6XGL2:0.144
6pxw 1 P06213 98.6 0.0 EM
 2019-09-04 ASN A:152 A:152 115.0 0.719 H -74.2 -43.7 96.0 0.6 0.119 E:A6XGL2:0.119
ASN B:152 B:152 114.0 0.713 H -74.3 -43.7 92.0 0.575 0.138 F:A6XGL2:0.138
6ce7 1 P06213 99.89 0.0 EM
 2018-03-14 ASN A:152 B:152 124.0 0.775 T -72.3 102.1 124.0 0.775 0.0
ASN B:152 A:152 111.0 0.694 T -81.9 86.7 111.0 0.694 0.0
6ce9 1 P06213 98.6 0.0 EM
 2018-03-14 ASN A:152 A:152 123.0 0.769 S -112.1 104.4 123.0 0.769 0.0
ASN B:152 B:152 123.0 0.769 S -112.1 104.4 123.0 0.769 0.0
6ceb 1 P06213 98.6 0.0 EM
 2018-03-14 ASN A:152 A:152 124.0 0.775 S -113.3 101.8 124.0 0.775 0.0
ASN B:152 B:152 123.0 0.769 S -120.9 102.2 123.0 0.769 0.0
6hn4 1 P06213,P03069 95.7 0.0 EM
 2018-11-21 ASN A:152 NA:NA DO NA DO DO DO NA NA NA
ASN B:152 F:152 132.0 0.825 T -89.0 75.5 123.0 0.769 0.056 A:P06213+P03069:0.056
6hn5 3 P06213,P03069 95.7 0.0 EM
 2018-11-21 ASN C:152 E:152 84.0 0.525 S -89.0 149.9 84.0 0.525 0.0
ASN D:152 NA:NA DO NA DO DO DO NA NA NA
4zxb 5 P06213 95.48 0.0 X-RAY
 2016-02-24 ASN E:152 E:152 126.0 0.787 T -99.6 72.7 121.0 0.756 0.031 E:P06213:0.031
6sof 1 P06213 100.0 0.0 EM
 2019-11-13 ASN A:152 A:152 69.0 0.431 T -84.3 16.7 59.0 0.369 0.062 I:P01308:0.062
ASN C:152 C:152 99.0 0.619 G -96.8 -2.1 76.0 0.475 0.144 K:P01308:0.144
7qid 1 P06213 100.0 0.0 EM
 2022-02-02 ASN A:152 A:152 75.0 0.469 T -81.9 -0.1 57.0 0.356 0.113 G:P01308:0.113
ASN C:152 C:152 79.0 0.494 G -85.8 9.1 79.0 0.494 0.0
5kqv 5 P06213 99.83 0.0 X-RAY
 2017-07-19 ASN E:152 E:152 87.0 0.544 S -95.1 -164.0 81.0 0.506 0.038 I:None:0.037
ASN F:152 F:152 89.0 0.556 T -94.8 -163.9 83.0 0.519 0.037 C:None:0.037
2hr7 1 P06213 99.59 0.0 X-RAY
 2006-08-15 ASN A:152 A:152 109.0 0.681 S -101.2 -161.3 105.0 0.656 0.025 B:P06213:0.025
 GOL
HOH
 3.412
2.611
 OD1
OD1
 C1
O
ASN B:152 B:152 109.0 0.681 H -75.8 10.6 81.0 0.506 0.175 A:P06213:0.175
 HOH
 6.818
 N
 O
4oga 5 P06213 99.68 0.0 X-RAY
 2014-08-27 ASN E:152 E:152 118.0 0.738 G -68.6 -26.6 118.0 0.738 0.0
4xss 2 P06213 99.68 0.0 X-RAY
 2015-06-10 ASN B:152 E:152 77.0 0.481 S -91.5 -169.7 77.0 0.481 0.0
4xst 1 P06213 99.68 0.0 X-RAY
 2015-06-10 ASN A:152 NA:NA DO NA DO DO DO NA NA NA
5j3h 4 P06213 99.68 0.0 X-RAY
 2016-06-15 ASN D:152 NA:NA DO NA DO DO DO NA NA NA
6vep 5 P06213 99.68 0.0 X-RAY
 2020-06-03 ASN E:152 E:152 135.0 0.844 H -102.5 -5.7 135.0 0.844 0.0
ASN K:152 K:152 120.0 0.75 G -104.1 16.9 NA NA NA
ASN Q:152 NA:NA DO NA DO DO DO NA NA NA
ASN W:152 W:152 163.0 1.0 S 61.0 80.9 NA NA NA
6veq 3 P06213 99.68 0.0 X-RAY
 2020-06-03 ASN C:152 E:152 117.0 0.731 G -77.6 2.7 117.0 0.731 0.0
ASN G:152 K:152 117.0 0.731 G -78.0 2.7 NA NA NA
7kd6 4 P06213 99.68 0.0 X-RAY
 2021-10-13 ASN D:152 E:152 95.0 0.594 H -127.5 -1.8 95.0 0.594 0.0
ASN I:152 K:152 94.0 0.588 T -69.0 4.8 NA NA NA
ASN N:152 Q:152 97.0 0.606 S -152.6 174.6 NA NA NA
ASN S:152 W:152 157.0 0.981 S -80.2 -33.8 NA NA NA
3w11 5 P06213 99.68 0.0 X-RAY
 2013-01-09 ASN E:152 E:152 110.0 0.688 S -103.3 69.7 110.0 0.688 0.0
3w12 1 P06213 99.68 0.0 X-RAY
 2013-01-09 ASN A:152 E:152 101.0 0.631 G -95.0 19.4 101.0 0.631 0.0
3w13 1 P06213 99.68 0.0 X-RAY
 2013-01-09 ASN A:152 E:152 100.0 0.625 G -93.3 13.1 100.0 0.625 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06213-f1 1 P06213 100.0 0.0 ASN A:179 A:179 115.0 0.719 G -91.9 5.0