Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 7267670 . C A CCDS12176.1:NM_000208.2:c.338cGa>cTa_NP_000199.2:p.113R>L Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7bw7 1 P06213 100.0 0.0 EM
 2021-04-14 ARG A:86 A:86 114.0 0.507 S -142.4 90.2 114.0 0.507 0.0
ARG B:86 NA:NA DO NA DO DO DO NA NA NA
7bw8 1 P06213 100.0 0.0 EM
 2021-04-14 ARG A:86 A:86 126.0 0.56 S -133.0 101.5 126.0 0.56 0.0
ARG B:86 NA:NA DO NA DO DO DO NA NA NA
7bwa 1 P06213 100.0 0.0 EM
 2021-04-14 ARG A:86 A:86 150.0 0.667 S -78.1 177.3 150.0 0.667 0.0
ARG B:86 C:86 147.0 0.653 S -78.0 177.3 NA NA NA
7pg0 1 P06213 99.13 0.0 EM
 2022-02-02 ARG A:113 A:86 59.0 0.262 S -129.7 138.6 59.0 0.262 0.0
ARG B:113 B:86 95.0 0.422 S -126.9 146.4 95.0 0.422 0.0
7pg2 1 P06213 99.13 0.0 EM
 2022-02-02 ARG A:113 A:86 83.0 0.369 S -132.9 156.7 83.0 0.369 0.0
ARG B:113 B:86 61.0 0.271 S -110.9 157.4 61.0 0.271 0.0
7pg3 1 P06213 99.13 0.0 EM
 2022-02-02 ARG A:113 A:86 82.0 0.364 S -113.5 128.1 82.0 0.364 0.0
ARG B:113 B:86 88.0 0.391 -126.9 153.2 88.0 0.391 0.0
7pg4 1 P06213 99.13 0.0 EM
 2022-02-02 ARG A:113 A:86 60.0 0.267 S -115.5 149.2 60.0 0.267 0.0
ARG B:113 B:86 11.0 0.049 S -103.5 124.8 11.0 0.049 0.0
6pxv 1 P06213 98.6 0.0 EM
 2019-09-04 ARG A:86 A:86 104.0 0.462 S -124.9 136.7 104.0 0.462 0.0
ARG B:86 C:86 106.0 0.471 S -124.9 136.7 106.0 0.471 0.0
6pxw 1 P06213 98.6 0.0 EM
 2019-09-04 ARG A:86 A:86 106.0 0.471 S -124.9 136.7 106.0 0.471 0.0
ARG B:86 B:86 105.0 0.467 S -124.9 136.7 105.0 0.467 0.0
6ce7 1 P06213 99.89 0.0 EM
 2018-03-14 ARG A:86 B:86 102.0 0.453 S -120.6 142.8 102.0 0.453 0.0
ARG B:86 A:86 129.0 0.573 S -122.9 130.8 129.0 0.573 0.0
6ce9 1 P06213 98.6 0.0 EM
 2018-03-14 ARG A:86 A:86 112.0 0.498 S -81.6 114.5 112.0 0.498 0.0
ARG B:86 B:86 114.0 0.507 S -81.7 114.5 114.0 0.507 0.0
6ceb 1 P06213 98.6 0.0 EM
 2018-03-14 ARG A:86 A:86 111.0 0.493 S -89.0 113.9 111.0 0.493 0.0
ARG B:86 B:86 109.0 0.484 S -83.8 114.2 109.0 0.484 0.0
6hn4 1 P06213,P03069 95.7 0.0 EM
 2018-11-21 ARG A:86 NA:NA DO NA DO DO DO NA NA NA
ARG B:86 F:86 127.0 0.564 S -121.0 144.2 127.0 0.564 0.0
6hn5 3 P06213,P03069 95.7 0.0 EM
 2018-11-21 ARG C:86 E:86 147.0 0.653 S -127.4 121.0 147.0 0.653 0.0
ARG D:86 NA:NA DO NA DO DO DO NA NA NA
4zxb 5 P06213 95.48 0.0 X-RAY
 2016-02-24 ARG E:86 E:86 156.0 0.693 S -122.2 144.2 156.0 0.693 0.0
6sof 1 P06213 100.0 0.0 EM
 2019-11-13 ARG A:86 A:86 174.0 0.773 S -130.5 85.1 174.0 0.773 0.0
ARG C:86 C:86 135.0 0.6 S -127.0 178.4 135.0 0.6 0.0
7qid 1 P06213 100.0 0.0 EM
 2022-02-02 ARG A:86 A:86 96.0 0.427 S -92.1 148.6 96.0 0.427 0.0
ARG C:86 C:86 106.0 0.471 S -79.3 154.9 106.0 0.471 0.0
5kqv 5 P06213 99.83 0.0 X-RAY
 2017-07-19 ARG E:86 E:86 164.0 0.729 S -122.8 145.0 164.0 0.729 0.0
ARG F:86 F:86 158.0 0.702 S -123.2 145.1 158.0 0.702 0.0
2hr7 1 P06213 99.59 0.0 X-RAY
 2006-08-15 ARG A:86 A:86 155.0 0.689 S -118.4 151.2 155.0 0.689 0.0 MAN
SO4
GOL
GOL
HOH
 8.562
3.112
9.363
6.859
3.983
 N
NE
NE
NH2
CB
 O6
O4
O1
O3
O
ARG B:86 B:86 184.0 0.818 S -121.7 147.1 180.0 0.8 0.018 A:P06213:0.018
 MAN
GOL
SO4
GOL
HOH
 7.732
9.740
3.576
8.736
3.799
 N
NH1
CA
C
CB
 O4
O3
O2
O2
O
4oga 5 P06213 99.68 0.0 X-RAY
 2014-08-27 ARG E:86 E:86 104.0 0.462 S -125.5 144.7 104.0 0.462 0.0 MAN
 8.399
 N
 O4
4xss 2 P06213 99.68 0.0 X-RAY
 2015-06-10 ARG B:86 E:86 181.0 0.804 S -123.4 145.8 181.0 0.804 0.0
4xst 1 P06213 99.68 0.0 X-RAY
 2015-06-10 ARG A:86 E:86 172.0 0.764 S -123.5 145.3 172.0 0.764 0.0 SO4
 3.330
 CA
 O1
5j3h 4 P06213 99.68 0.0 X-RAY
 2016-06-15 ARG D:86 E:86 182.0 0.809 S -121.7 144.9 182.0 0.809 0.0
6vep 5 P06213 99.68 0.0 X-RAY
 2020-06-03 ARG E:86 E:86 124.0 0.551 S -128.8 132.8 124.0 0.551 0.0
ARG K:86 K:86 124.0 0.551 S -129.5 133.2 NA NA NA
ARG Q:86 Q:86 94.0 0.418 S -128.5 132.2 NA NA NA
ARG W:86 W:86 124.0 0.551 S -129.9 132.3 NA NA NA
6veq 3 P06213 99.68 0.0 X-RAY
 2020-06-03 ARG C:86 E:86 163.0 0.724 S -127.8 130.1 163.0 0.724 0.0 MAN
SO4
 7.555
3.765
 N
CA
 O4
O3
ARG G:86 K:86 177.0 0.787 S -128.9 130.6 NA NA NA
7kd6 4 P06213 99.68 0.0 X-RAY
 2021-10-13 ARG D:86 E:86 105.0 0.467 S -123.3 136.4 105.0 0.467 0.0 HOH
 3.511
 NE
 O
ARG I:86 K:86 175.0 0.778 S -127.0 133.6 NA NA NA
ARG N:86 Q:86 187.0 0.831 S -128.2 135.1 NA NA NA
ARG S:86 W:86 183.0 0.813 S -127.0 138.2 NA NA NA
3w11 5 P06213 99.68 0.0 X-RAY
 2013-01-09 ARG E:86 E:86 114.0 0.507 S -129.3 139.1 114.0 0.507 0.0 MAN
 7.869
 N
 O6
3w12 1 P06213 99.68 0.0 X-RAY
 2013-01-09 ARG A:86 E:86 116.0 0.516 S -119.5 144.0 116.0 0.516 0.0 MAN
 8.472
 N
 O4
3w13 1 P06213 99.68 0.0 X-RAY
 2013-01-09 ARG A:86 E:86 108.0 0.48 S -123.0 141.7 108.0 0.48 0.0 MAN
 8.514
 N
 C6

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06213-f1 1 P06213 100.0 0.0 ARG A:113 A:113 137.0 0.609 S -118.0 145.9