Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 7267734 . G A CCDS12176.1:NM_000208.2:c.274Cgg>Tgg_NP_000199.2:p.92R>W Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7bw7 1 P06213 100.0 0.0 EM
 2021-04-14 ARG A:65 A:65 71.0 0.316 E 54.2 66.1 12.0 0.053 0.263 C:P01308+A6XGL2:0.262
ARG B:65 NA:NA DO NA DO DO DO NA NA NA
7bw8 1 P06213 100.0 0.0 EM
 2021-04-14 ARG A:65 A:65 78.0 0.347 E 57.2 69.9 14.0 0.062 0.285 C:P01308+A6XGL2:0.28
B:P06213:0.018
ARG B:65 NA:NA DO NA DO DO DO NA NA NA
7bwa 1 P06213 100.0 0.0 EM
 2021-04-14 ARG A:65 A:65 84.0 0.373 57.5 67.3 84.0 0.373 0.0
ARG B:65 C:65 83.0 0.369 57.5 67.2 NA NA NA
7pg0 1 P06213 99.13 0.0 EM
 2022-02-02 ARG A:92 A:65 63.0 0.28 S 56.5 62.5 59.0 0.262 0.018 D:P01308:0.018
ARG B:92 B:65 83.0 0.369 S 48.9 49.6 12.0 0.053 0.316 F:P01308:0.316
7pg2 1 P06213 99.13 0.0 EM
 2022-02-02 ARG A:92 A:65 49.0 0.218 E 53.2 62.1 35.0 0.156 0.062 D:P01308:0.062
ARG B:92 B:65 87.0 0.387 E 44.9 59.9 28.0 0.124 0.263 F:P01308:0.262
7pg3 1 P06213 99.13 0.0 EM
 2022-02-02 ARG A:92 A:65 56.0 0.249 E 47.0 61.7 45.0 0.2 0.049 D:P01308:0.049
ARG B:92 B:65 89.0 0.396 E 53.4 62.0 39.0 0.173 0.223 F:P01308:0.222
7pg4 1 P06213 99.13 0.0 EM
 2022-02-02 ARG A:92 A:65 40.0 0.178 E 49.0 61.7 30.0 0.133 0.045 D:P01308:0.044
ARG B:92 B:65 63.0 0.28 E 54.9 62.1 63.0 0.28 0.0
6pxv 1 P06213 98.6 0.0 EM
 2019-09-04 ARG A:65 A:65 68.0 0.302 E 58.4 65.9 23.0 0.102 0.2 C:A6XGL2:0.2
ARG B:65 C:65 69.0 0.307 E 58.5 66.0 22.0 0.098 0.209 D:A6XGL2:0.209
6pxw 1 P06213 98.6 0.0 EM
 2019-09-04 ARG A:65 A:65 67.0 0.298 E 58.4 66.0 22.0 0.098 0.2 C:A6XGL2:0.2
ARG B:65 B:65 67.0 0.298 E 58.5 65.9 22.0 0.098 0.2 D:A6XGL2:0.2
6ce7 1 P06213 99.89 0.0 EM
 2018-03-14 ARG A:65 B:65 84.0 0.373 E 55.7 53.0 84.0 0.373 0.0
ARG B:65 A:65 87.0 0.387 59.0 24.5 21.0 0.093 0.294 D:P01318:0.293
6ce9 1 P06213 98.6 0.0 EM
 2018-03-14 ARG A:65 A:65 82.0 0.364 E 59.1 64.2 17.0 0.076 0.288 G:P01318:0.289
H:P06213:0.013
ARG B:65 B:65 82.0 0.364 E 59.1 64.1 18.0 0.08 0.284 C:P06213:0.013
E:P01318:0.284
6ceb 1 P06213 98.6 0.0 EM
 2018-03-14 ARG A:65 A:65 86.0 0.382 E 59.8 61.1 17.0 0.076 0.306 G:P01318:0.307
H:P06213:0.013
B:P06213:0.004
ARG B:65 B:65 83.0 0.369 E 59.1 63.4 16.0 0.071 0.298 E:P01318:0.298
C:P06213:0.013
6hn4 1 P06213,P03069 95.7 0.0 EM
 2018-11-21 ARG A:65 NA:NA DO NA DO DO DO NA NA NA
ARG B:65 F:65 89.0 0.396 E 49.6 55.7 24.0 0.107 0.289 A:P06213+P03069:0.289
6hn5 3 P06213,P03069 95.7 0.0 EM
 2018-11-21 ARG C:65 E:65 58.0 0.258 E 57.0 68.3 18.0 0.08 0.178 B:P01308:0.178
ARG D:65 NA:NA DO NA DO DO DO NA NA NA
4zxb 5 P06213 95.48 0.0 X-RAY
 2016-02-24 ARG E:65 E:65 78.0 0.347 E 48.5 55.0 10.0 0.044 0.303 E:P06213:0.302
6sof 1 P06213 100.0 0.0 EM
 2019-11-13 ARG A:65 A:65 86.0 0.382 E 57.4 63.9 12.0 0.053 0.329 H:P01308:0.329
C:P06213:0.004
ARG C:65 C:65 121.0 0.538 E 56.8 66.4 49.0 0.218 0.32 F:P01308:0.32
7qid 1 P06213 100.0 0.0 EM
 2022-02-02 ARG A:65 A:65 87.0 0.387 E 58.4 65.2 34.0 0.151 0.236 F:P01308:0.236
ARG C:65 C:65 81.0 0.36 S 57.4 66.6 81.0 0.36 0.0
5kqv 5 P06213 99.83 0.0 X-RAY
 2017-07-19 ARG E:65 E:65 72.0 0.32 E 51.6 53.7 27.0 0.12 0.2 B:P01317:0.2
ARG F:65 F:65 70.0 0.311 E 51.5 53.8 24.0 0.107 0.204 H:P01317:0.204
2hr7 1 P06213 99.59 0.0 X-RAY
 2006-08-15 ARG A:65 A:65 67.0 0.298 E 50.3 53.6 67.0 0.298 0.0 P33
GOL
GOL
HOH
 3.935
3.685
2.978
3.640
 NE
NH2
NH1
NH2
 C14
C3
O2
O
ARG B:65 B:65 93.0 0.413 E 54.4 54.0 33.0 0.147 0.266 A:P06213:0.267
 NAG
P33
HOH
 6.902
5.553
2.838
 NH2
NH1
NH1
 C8
O22
O
4oga 5 P06213 99.68 0.0 X-RAY
 2014-08-27 ARG E:65 E:65 69.0 0.307 E 53.1 51.1 12.0 0.053 0.254 B:P01308:0.253
4xss 2 P06213 99.68 0.0 X-RAY
 2015-06-10 ARG B:65 E:65 68.0 0.302 E 52.0 52.4 22.0 0.098 0.204 A:P05019:0.204
4xst 1 P06213 99.68 0.0 X-RAY
 2015-06-10 ARG A:65 E:65 121.0 0.538 E 53.2 53.8 99.0 0.44 0.098 B:P15127:0.098
5j3h 4 P06213 99.68 0.0 X-RAY
 2016-06-15 ARG D:65 E:65 80.0 0.356 E 48.2 54.8 70.0 0.311 0.045 A:None:0.044
6vep 5 P06213 99.68 0.0 X-RAY
 2020-06-03 ARG E:65 E:65 68.0 0.302 E 51.4 50.0 6.0 0.027 0.275 B:P01308:0.276
ARG K:65 K:65 65.0 0.289 E 50.3 50.2 NA NA NA
ARG Q:65 Q:65 66.0 0.293 E 51.8 49.7 NA NA NA
ARG W:65 W:65 65.0 0.289 E 52.2 49.3 NA NA NA
6veq 3 P06213 99.68 0.0 X-RAY
 2020-06-03 ARG C:65 E:65 73.0 0.324 E 60.0 54.2 24.0 0.107 0.217 B:A0A0B5A8Q2:0.218
ARG G:65 K:65 73.0 0.324 E 60.3 55.6 NA NA NA
7kd6 4 P06213 99.68 0.0 X-RAY
 2021-10-13 ARG D:65 E:65 62.0 0.276 E 52.5 50.6 6.0 0.027 0.249 A:None:0.249
 HOH
 7.909
 O
 O
ARG I:65 K:65 63.0 0.28 E 51.8 50.1 NA NA NA
ARG N:65 Q:65 65.0 0.289 E 45.1 50.8 NA NA NA
ARG S:65 W:65 65.0 0.289 E 47.6 49.9 NA NA NA
3w11 5 P06213 99.68 0.0 X-RAY
 2013-01-09 ARG E:65 E:65 62.0 0.276 E 53.6 50.6 22.0 0.098 0.178 B:P01308:0.178
3w12 1 P06213 99.68 0.0 X-RAY
 2013-01-09 ARG A:65 E:65 71.0 0.316 E 54.4 56.6 20.0 0.089 0.227 E:P01308:0.227
3w13 1 P06213 99.68 0.0 X-RAY
 2013-01-09 ARG A:65 E:65 72.0 0.32 E 54.5 56.2 21.0 0.093 0.227 E:P01308:0.227

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06213-f1 1 P06213 100.0 0.0 ARG A:92 A:92 80.0 0.356 E 52.4 55.6