Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 7267841 | . | A | C | CCDS12176.1:NM_000208.2:c.167aTc>aGc_NP_000199.2:p.56I>S | Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 7bw7 | 1 | P06213 | 100.0 | 0.0 |
EM |
2021-04-14 | ILE | A:29 | A:29 | 2.0 | 0.011 | B | -106.4 | 125.8 | 2.0 | 0.011 | 0.0 | ||||||
| ILE | B:29 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 7bw8 | 1 | P06213 | 100.0 | 0.0 |
EM |
2021-04-14 | ILE | A:29 | A:29 | 3.0 | 0.017 | -101.9 | 123.8 | 3.0 | 0.017 | 0.0 | |||||||
| ILE | B:29 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 7bwa | 1 | P06213 | 100.0 | 0.0 |
EM |
2021-04-14 | ILE | A:29 | A:29 | 8.0 | 0.046 | E | -116.8 | 120.1 | 8.0 | 0.046 | 0.0 | ||||||
| ILE | B:29 | C:29 | 7.0 | 0.04 | E | -116.7 | 120.1 | NA | NA | NA | |||||||||||||
| 7pg0 | 1 | P06213 | 99.13 | 0.0 |
EM |
2022-02-02 | ILE | A:56 | A:29 | 1.0 | 0.006 | E | -95.6 | 90.1 | 1.0 | 0.006 | 0.0 | ||||||
| ILE | B:56 | B:29 | 0.0 | 0.0 | E | -90.0 | 86.1 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 7pg2 | 1 | P06213 | 99.13 | 0.0 |
EM |
2022-02-02 | ILE | A:56 | A:29 | 1.0 | 0.006 | E | -121.6 | 107.1 | 1.0 | 0.006 | 0.0 | ||||||
| ILE | B:56 | B:29 | 2.0 | 0.011 | E | -89.3 | 87.4 | 2.0 | 0.011 | 0.0 | |||||||||||||
| 7pg3 | 1 | P06213 | 99.13 | 0.0 |
EM |
2022-02-02 | ILE | A:56 | A:29 | 0.0 | 0.0 | E | -132.8 | 98.2 | 0.0 | 0.0 | 0.0 | ||||||
| ILE | B:56 | B:29 | 0.0 | 0.0 | E | -87.6 | 86.0 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 7pg4 | 1 | P06213 | 99.13 | 0.0 |
EM |
2022-02-02 | ILE | A:56 | A:29 | 5.0 | 0.029 | E | -131.1 | 99.5 | 5.0 | 0.029 | 0.0 | ||||||
| ILE | B:56 | B:29 | 0.0 | 0.0 | E | -105.3 | 119.0 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 6pxv | 1 | P06213 | 98.6 | 0.0 |
EM |
2019-09-04 | ILE | A:29 | A:29 | 0.0 | 0.0 | E | -96.4 | 117.6 | 0.0 | 0.0 | 0.0 | ||||||
| ILE | B:29 | C:29 | 0.0 | 0.0 | E | -96.4 | 117.5 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 6pxw | 1 | P06213 | 98.6 | 0.0 |
EM |
2019-09-04 | ILE | A:29 | A:29 | 0.0 | 0.0 | E | -96.4 | 117.6 | 0.0 | 0.0 | 0.0 | ||||||
| ILE | B:29 | B:29 | 0.0 | 0.0 | E | -96.4 | 117.6 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 6ce7 | 1 | P06213 | 99.89 | 0.0 |
EM |
2018-03-14 | ILE | A:29 | B:29 | 0.0 | 0.0 | E | -103.2 | 110.9 | 0.0 | 0.0 | 0.0 | ||||||
| ILE | B:29 | A:29 | 14.0 | 0.08 | E | -89.8 | 123.0 | 14.0 | 0.08 | 0.0 | |||||||||||||
| 6ce9 | 1 | P06213 | 98.6 | 0.0 |
EM |
2018-03-14 | ILE | A:29 | A:29 | 6.0 | 0.034 | E | -85.9 | 122.9 | 6.0 | 0.034 | 0.0 | ||||||
| ILE | B:29 | B:29 | 6.0 | 0.034 | E | -85.9 | 122.9 | 6.0 | 0.034 | 0.0 | |||||||||||||
| 6ceb | 1 | P06213 | 98.6 | 0.0 |
EM |
2018-03-14 | ILE | A:29 | A:29 | 9.0 | 0.051 | E | -81.9 | 120.6 | 9.0 | 0.051 | 0.0 | ||||||
| ILE | B:29 | B:29 | 6.0 | 0.034 | E | -82.1 | 120.4 | 6.0 | 0.034 | 0.0 | |||||||||||||
| 6hn4 | 1 | P06213,P03069 | 95.7 | 0.0 |
EM |
2018-11-21 | ILE | A:29 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| ILE | B:29 | F:29 | 1.0 | 0.006 | E | -100.3 | 114.4 | 1.0 | 0.006 | 0.0 | |||||||||||||
| 6hn5 | 3 | P06213,P03069 | 95.7 | 0.0 |
EM |
2018-11-21 | ILE | C:29 | E:29 | 0.0 | 0.0 | E | -106.1 | 113.3 | 0.0 | 0.0 | 0.0 | ||||||
| ILE | D:29 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 4zxb | 5 | P06213 | 95.48 | 0.0 |
X-RAY |
2016-02-24 | ILE | E:29 | E:29 | 0.0 | 0.0 | E | -101.0 | 113.7 | 0.0 | 0.0 | 0.0 | ||||||
| 6sof | 1 | P06213 | 100.0 | 0.0 |
EM |
2019-11-13 | ILE | A:29 | A:29 | 15.0 | 0.086 | E | -114.1 | 143.0 | 15.0 | 0.086 | 0.0 | ||||||
| ILE | C:29 | C:29 | 20.0 | 0.114 | -137.7 | 140.4 | 20.0 | 0.114 | 0.0 | ||||||||||||||
| 7qid | 1 | P06213 | 100.0 | 0.0 |
EM |
2022-02-02 | ILE | A:29 | A:29 | 7.0 | 0.04 | E | -97.9 | 143.9 | 7.0 | 0.04 | 0.0 | ||||||
| ILE | C:29 | C:29 | 8.0 | 0.046 | E | -111.8 | 113.0 | 8.0 | 0.046 | 0.0 | |||||||||||||
| 5kqv | 5 | P06213 | 99.83 | 0.0 |
X-RAY |
2017-07-19 | ILE | E:29 | E:29 | 0.0 | 0.0 | E | -101.7 | 114.2 | 0.0 | 0.0 | 0.0 | ||||||
| ILE | F:29 | F:29 | 0.0 | 0.0 | E | -101.8 | 114.6 | 0.0 | 0.0 | 0.0 |
NAG |
9.036 |
CG1 |
C8 |
|||||||||
| 2hr7 | 1 | P06213 | 99.59 | 0.0 |
X-RAY |
2006-08-15 | ILE | A:29 | A:29 | 0.0 | 0.0 | E | -101.3 | 117.4 | 0.0 | 0.0 | 0.0 |
HOH |
6.158 |
CG2 |
O |
||
| ILE | B:29 | B:29 | 0.0 | 0.0 | E | -98.7 | 115.3 | 0.0 | 0.0 | 0.0 |
HOH |
6.081 |
CG2 |
O |
|||||||||
| 4oga | 5 | P06213 | 99.68 | 0.0 |
X-RAY |
2014-08-27 | ILE | E:29 | E:29 | 0.0 | 0.0 | E | -101.8 | 115.1 | 0.0 | 0.0 | 0.0 | ||||||
| 4xss | 2 | P06213 | 99.68 | 0.0 |
X-RAY |
2015-06-10 | ILE | B:29 | E:29 | 0.0 | 0.0 | E | -104.1 | 113.3 | 0.0 | 0.0 | 0.0 | ||||||
| 4xst | 1 | P06213 | 99.68 | 0.0 |
X-RAY |
2015-06-10 | ILE | A:29 | E:29 | 0.0 | 0.0 | E | -104.2 | 112.4 | 0.0 | 0.0 | 0.0 | ||||||
| 5j3h | 4 | P06213 | 99.68 | 0.0 |
X-RAY |
2016-06-15 | ILE | D:29 | E:29 | 0.0 | 0.0 | E | -101.8 | 113.8 | 0.0 | 0.0 | 0.0 | ||||||
| 6vep | 5 | P06213 | 99.68 | 0.0 |
X-RAY |
2020-06-03 | ILE | E:29 | E:29 | 0.0 | 0.0 | E | -103.6 | 107.5 | 0.0 | 0.0 | 0.0 | ||||||
| ILE | K:29 | K:29 | 0.0 | 0.0 | E | -103.1 | 108.3 | NA | NA | NA | |||||||||||||
| ILE | Q:29 | Q:29 | 0.0 | 0.0 | E | -103.8 | 109.3 | NA | NA | NA | |||||||||||||
| ILE | W:29 | W:29 | 0.0 | 0.0 | E | -103.7 | 107.4 | NA | NA | NA | |||||||||||||
| 6veq | 3 | P06213 | 99.68 | 0.0 |
X-RAY |
2020-06-03 | ILE | C:29 | E:29 | 0.0 | 0.0 | E | -97.1 | 98.6 | 0.0 | 0.0 | 0.0 | ||||||
| ILE | G:29 | K:29 | 0.0 | 0.0 | E | -96.4 | 99.2 | NA | NA | NA | |||||||||||||
| 7kd6 | 4 | P06213 | 99.68 | 0.0 |
X-RAY |
2021-10-13 | ILE | D:29 | E:29 | 0.0 | 0.0 | E | -102.1 | 109.4 | 0.0 | 0.0 | 0.0 |
HOH |
9.197 |
O |
O |
||
| ILE | I:29 | K:29 | 1.0 | 0.006 | E | -99.9 | 118.5 | NA | NA | NA | |||||||||||||
| ILE | N:29 | Q:29 | 0.0 | 0.0 | E | -94.5 | 117.9 | NA | NA | NA | |||||||||||||
| ILE | S:29 | W:29 | 1.0 | 0.006 | E | -100.9 | 118.0 | NA | NA | NA | |||||||||||||
| 3w11 | 5 | P06213 | 99.68 | 0.0 |
X-RAY |
2013-01-09 | ILE | E:29 | E:29 | 0.0 | 0.0 | E | -99.3 | 114.7 | 0.0 | 0.0 | 0.0 | ||||||
| 3w12 | 1 | P06213 | 99.68 | 0.0 |
X-RAY |
2013-01-09 | ILE | A:29 | E:29 | 1.0 | 0.006 | E | -93.1 | 115.8 | 1.0 | 0.006 | 0.0 | ||||||
| 3w13 | 1 | P06213 | 99.68 | 0.0 |
X-RAY |
2013-01-09 | ILE | A:29 | E:29 | 1.0 | 0.006 | E | -95.0 | 111.1 | 1.0 | 0.006 | 0.0 | ||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p06213-f1 | 1 | P06213 | 100.0 | 0.0 | ILE | A:56 | A:56 | 0.0 | 0.0 | E | -96.5 | 107.7 | |