Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 7267844 . A C CCDS12176.1:NM_000208.2:c.164gTc>gGc_NP_000199.2:p.55V>G Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7bw7 1 P06213 100.0 0.0 EM
 2021-04-14 VAL A:28 A:28 18.0 0.116 -151.9 144.1 18.0 0.116 0.0
VAL B:28 NA:NA DO NA DO DO DO NA NA NA
7bw8 1 P06213 100.0 0.0 EM
 2021-04-14 VAL A:28 A:28 31.0 0.2 -148.9 139.7 31.0 0.2 0.0
VAL B:28 NA:NA DO NA DO DO DO NA NA NA
7bwa 1 P06213 100.0 0.0 EM
 2021-04-14 VAL A:28 A:28 20.0 0.129 E -129.3 157.6 20.0 0.129 0.0
VAL B:28 C:28 21.0 0.135 E -129.3 157.6 NA NA NA
7pg0 1 P06213 99.13 0.0 EM
 2022-02-02 VAL A:55 A:28 0.0 0.0 E -131.4 122.4 0.0 0.0 0.0
VAL B:55 B:28 0.0 0.0 E -125.5 118.3 0.0 0.0 0.0
7pg2 1 P06213 99.13 0.0 EM
 2022-02-02 VAL A:55 A:28 0.0 0.0 E -126.5 130.4 0.0 0.0 0.0
VAL B:55 B:28 9.0 0.058 E -137.1 126.6 9.0 0.058 0.0
7pg3 1 P06213 99.13 0.0 EM
 2022-02-02 VAL A:55 A:28 1.0 0.006 E -144.3 142.2 1.0 0.006 0.0
VAL B:55 B:28 2.0 0.013 E -130.4 108.1 2.0 0.013 0.0
7pg4 1 P06213 99.13 0.0 EM
 2022-02-02 VAL A:55 A:28 6.0 0.039 E -150.2 160.8 6.0 0.039 0.0
VAL B:55 B:28 23.0 0.148 E -125.1 124.7 23.0 0.148 0.0
6pxv 1 P06213 98.6 0.0 EM
 2019-09-04 VAL A:28 A:28 2.0 0.013 E -128.8 134.6 2.0 0.013 0.0
VAL B:28 C:28 2.0 0.013 E -128.9 134.6 2.0 0.013 0.0
6pxw 1 P06213 98.6 0.0 EM
 2019-09-04 VAL A:28 A:28 3.0 0.019 E -128.9 134.6 3.0 0.019 0.0
VAL B:28 B:28 2.0 0.013 E -128.9 134.6 2.0 0.013 0.0
6ce7 1 P06213 99.89 0.0 EM
 2018-03-14 VAL A:28 B:28 13.0 0.084 E -125.7 136.6 13.0 0.084 0.0
VAL B:28 A:28 43.0 0.277 E -140.2 129.8 43.0 0.277 0.0
6ce9 1 P06213 98.6 0.0 EM
 2018-03-14 VAL A:28 A:28 6.0 0.039 E -140.2 117.7 6.0 0.039 0.0
VAL B:28 B:28 8.0 0.052 E -140.3 117.8 8.0 0.052 0.0
6ceb 1 P06213 98.6 0.0 EM
 2018-03-14 VAL A:28 A:28 9.0 0.058 E -134.5 114.1 9.0 0.058 0.0
VAL B:28 B:28 9.0 0.058 E -136.5 117.1 9.0 0.058 0.0
6hn4 1 P06213,P03069 95.7 0.0 EM
 2018-11-21 VAL A:28 NA:NA DO NA DO DO DO NA NA NA
VAL B:28 F:28 22.0 0.142 E -132.9 134.3 22.0 0.142 0.0
6hn5 3 P06213,P03069 95.7 0.0 EM
 2018-11-21 VAL C:28 E:28 0.0 0.0 E -134.3 137.3 0.0 0.0 0.0
VAL D:28 NA:NA DO NA DO DO DO NA NA NA
4zxb 5 P06213 95.48 0.0 X-RAY
 2016-02-24 VAL E:28 E:28 0.0 0.0 E -134.7 133.0 0.0 0.0 0.0
6sof 1 P06213 100.0 0.0 EM
 2019-11-13 VAL A:28 A:28 4.0 0.026 E -142.2 149.3 4.0 0.026 0.0
VAL C:28 C:28 22.0 0.142 -99.1 159.7 22.0 0.142 0.0
7qid 1 P06213 100.0 0.0 EM
 2022-02-02 VAL A:28 A:28 18.0 0.116 S -140.3 165.4 18.0 0.116 0.0
VAL C:28 C:28 12.0 0.077 E -141.5 127.5 12.0 0.077 0.0
5kqv 5 P06213 99.83 0.0 X-RAY
 2017-07-19 VAL E:28 E:28 13.0 0.084 E -137.1 134.3 13.0 0.084 0.0
VAL F:28 F:28 0.0 0.0 E -136.6 134.2 0.0 0.0 0.0 NAG
 8.981
 O
 C8
2hr7 1 P06213 99.59 0.0 X-RAY
 2006-08-15 VAL A:28 A:28 19.0 0.123 E -129.1 133.5 19.0 0.123 0.0 GOL
HOH
 7.832
6.374
 CG2
CG2
 C1
O
VAL B:28 B:28 13.0 0.084 E -142.8 130.5 13.0 0.084 0.0 GOL
HOH
 8.161
6.205
 CG2
N
 O1
O
4oga 5 P06213 99.68 0.0 X-RAY
 2014-08-27 VAL E:28 E:28 16.0 0.103 E -127.4 135.2 16.0 0.103 0.0
4xss 2 P06213 99.68 0.0 X-RAY
 2015-06-10 VAL B:28 E:28 0.0 0.0 E -128.4 137.4 0.0 0.0 0.0 FUC
 9.684
 CG2
 C6
4xst 1 P06213 99.68 0.0 X-RAY
 2015-06-10 VAL A:28 E:28 18.0 0.116 E -127.4 137.8 18.0 0.116 0.0
5j3h 4 P06213 99.68 0.0 X-RAY
 2016-06-15 VAL D:28 E:28 16.0 0.103 E -130.4 134.2 16.0 0.103 0.0
6vep 5 P06213 99.68 0.0 X-RAY
 2020-06-03 VAL E:28 E:28 14.0 0.09 E -134.3 129.7 14.0 0.09 0.0 HOH
 9.486
 CG1
 O
VAL K:28 K:28 15.0 0.097 E -135.2 130.5 NA NA NA
VAL Q:28 Q:28 16.0 0.103 E -134.5 130.0 NA NA NA
VAL W:28 W:28 14.0 0.09 E -135.0 131.2 NA NA NA
6veq 3 P06213 99.68 0.0 X-RAY
 2020-06-03 VAL C:28 E:28 18.0 0.116 E -126.4 124.2 18.0 0.116 0.0
VAL G:28 K:28 17.0 0.11 E -126.2 124.2 NA NA NA
7kd6 4 P06213 99.68 0.0 X-RAY
 2021-10-13 VAL D:28 E:28 15.0 0.097 E -132.6 132.8 15.0 0.097 0.0
VAL I:28 K:28 13.0 0.084 E -135.0 130.5 NA NA NA
VAL N:28 Q:28 13.0 0.084 E -142.5 124.0 NA NA NA
VAL S:28 W:28 13.0 0.084 E -136.5 133.0 NA NA NA
3w11 5 P06213 99.68 0.0 X-RAY
 2013-01-09 VAL E:28 E:28 17.0 0.11 E -125.3 130.6 17.0 0.11 0.0
3w12 1 P06213 99.68 0.0 X-RAY
 2013-01-09 VAL A:28 E:28 18.0 0.116 E -128.0 127.3 18.0 0.116 0.0
3w13 1 P06213 99.68 0.0 X-RAY
 2013-01-09 VAL A:28 E:28 17.0 0.11 E -130.9 129.3 17.0 0.11 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06213-f1 1 P06213 100.0 0.0 VAL A:55 A:55 0.0 0.0 E -129.9 131.1