Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 7267857 . C A CCDS12176.1:NM_000208.2:c.151Gag>Tag_NP_000199.2:p.51E>* Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7bw7 1 P06213 100.0 0.0 EM
 2021-04-14 GLU A:24 A:24 161.0 0.847 S -61.7 -66.2 161.0 0.847 0.0
GLU B:24 NA:NA DO NA DO DO DO NA NA NA
7bw8 1 P06213 100.0 0.0 EM
 2021-04-14 GLU A:24 A:24 144.0 0.758 S -58.5 -42.1 144.0 0.758 0.0
GLU B:24 NA:NA DO NA DO DO DO NA NA NA
7bwa 1 P06213 100.0 0.0 EM
 2021-04-14 GLU A:24 A:24 131.0 0.689 T -54.0 -67.0 131.0 0.689 0.0
GLU B:24 C:24 134.0 0.705 T -54.0 -67.0 NA NA NA
7pg0 1 P06213 99.13 0.0 EM
 2022-02-02 GLU A:51 A:24 59.0 0.311 T -69.5 -11.5 59.0 0.311 0.0
GLU B:51 B:24 65.0 0.342 H -57.5 -49.6 65.0 0.342 0.0
7pg2 1 P06213 99.13 0.0 EM
 2022-02-02 GLU A:51 A:24 49.0 0.258 G -99.0 0.8 49.0 0.258 0.0
GLU B:51 B:24 63.0 0.332 H -62.9 -49.0 63.0 0.332 0.0
7pg3 1 P06213 99.13 0.0 EM
 2022-02-02 GLU A:51 A:24 51.0 0.268 T -87.2 -7.5 51.0 0.268 0.0
GLU B:51 B:24 93.0 0.489 G -65.3 -41.2 93.0 0.489 0.0
7pg4 1 P06213 99.13 0.0 EM
 2022-02-02 GLU A:51 A:24 108.0 0.568 G -93.1 -9.0 108.0 0.568 0.0
GLU B:51 B:24 55.0 0.289 G -63.2 -15.8 55.0 0.289 0.0
6pxv 1 P06213 98.6 0.0 EM
 2019-09-04 GLU A:24 A:24 108.0 0.568 S -77.1 -49.0 108.0 0.568 0.0
GLU B:24 C:24 107.0 0.563 S -77.1 -49.1 107.0 0.563 0.0
6pxw 1 P06213 98.6 0.0 EM
 2019-09-04 GLU A:24 A:24 109.0 0.574 S -77.1 -49.1 109.0 0.574 0.0
GLU B:24 B:24 109.0 0.574 S -77.1 -49.0 109.0 0.574 0.0
6ce7 1 P06213 99.89 0.0 EM
 2018-03-14 GLU A:24 B:24 100.0 0.526 T -63.6 -66.7 100.0 0.526 0.0
GLU B:24 A:24 133.0 0.7 T -40.0 -46.6 133.0 0.7 0.0
6ce9 1 P06213 98.6 0.0 EM
 2018-03-14 GLU A:24 A:24 83.0 0.437 S -87.7 -61.7 83.0 0.437 0.0 NAG
NAG
FUC
 4.561
7.874
8.562
 OE1
OE1
OE1
 N2
O7
O5
GLU B:24 B:24 82.0 0.432 S -87.8 -61.7 82.0 0.432 0.0 NAG
NAG
FUC
 4.614
7.950
8.683
 OE1
OE1
OE1
 N2
O7
O5
6ceb 1 P06213 98.6 0.0 EM
 2018-03-14 GLU A:24 A:24 81.0 0.426 S -91.0 -57.1 81.0 0.426 0.0 NAG
NAG
FUC
 4.647
8.179
8.888
 N
OE1
OE1
 C8
O7
O5
GLU B:24 B:24 82.0 0.432 S -85.9 -64.1 82.0 0.432 0.0 NAG
NAG
FUC
 4.194
8.002
8.489
 OE1
OE1
OE1
 N2
C1
O5
6hn4 1 P06213,P03069 95.7 0.0 EM
 2018-11-21 GLU A:24 NA:NA DO NA DO DO DO NA NA NA
GLU B:24 F:24 124.0 0.653 T -36.1 -50.9 124.0 0.653 0.0 NAG
 3.200
 OE1
 N2
6hn5 3 P06213,P03069 95.7 0.0 EM
 2018-11-21 GLU C:24 E:24 96.0 0.505 T -73.3 -9.7 96.0 0.505 0.0 NAG
 3.162
 OE1
 O7
GLU D:24 NA:NA DO NA DO DO DO NA NA NA
4zxb 5 P06213 95.48 0.0 X-RAY
 2016-02-24 GLU E:24 E:24 126.0 0.663 T -35.6 -51.2 126.0 0.663 0.0 NAG
NAG
FUC
 3.212
4.880
8.133
 OE1
OE2
OE2
 N2
O7
C1
6sof 1 P06213 100.0 0.0 EM
 2019-11-13 GLU A:24 A:24 172.0 0.905 S -91.3 53.9 172.0 0.905 0.0
GLU C:24 C:24 138.0 0.726 S -56.3 -48.1 138.0 0.726 0.0
7qid 1 P06213 100.0 0.0 EM
 2022-02-02 GLU A:24 A:24 101.0 0.532 T -69.1 118.2 101.0 0.532 0.0
GLU C:24 C:24 126.0 0.663 S -137.0 -3.7 126.0 0.663 0.0
5kqv 5 P06213 99.83 0.0 X-RAY
 2017-07-19 GLU E:24 E:24 110.0 0.579 T -53.2 -30.8 110.0 0.579 0.0 NAG
FUC
 3.032
6.774
 OE2
OE2
 C3
O2
GLU F:24 F:24 109.0 0.574 T -53.2 -30.7 109.0 0.574 0.0 NAG
FUC
 3.200
6.810
 OE2
OE2
 C3
O5
2hr7 1 P06213 99.59 0.0 X-RAY
 2006-08-15 GLU A:24 A:24 111.0 0.584 T -58.9 -28.6 111.0 0.584 0.0 NAG
NAG
HOH
 2.543
6.276
3.237
 OE2
OE2
O
 N2
C1
O
GLU B:24 B:24 111.0 0.584 T -31.8 -53.8 111.0 0.584 0.0 NAG
HOH
 3.116
3.248
 OE1
O
 N2
O
4oga 5 P06213 99.68 0.0 X-RAY
 2014-08-27 GLU E:24 E:24 109.0 0.574 S -51.8 -38.4 109.0 0.574 0.0 NAG
 2.650
 OE2
 N2
4xss 2 P06213 99.68 0.0 X-RAY
 2015-06-10 GLU B:24 E:24 116.0 0.611 T -50.8 -30.3 116.0 0.611 0.0 NAG
NAG
FUC
 3.087
6.342
7.267
 OE2
OE2
OE2
 N2
C1
C1
4xst 1 P06213 99.68 0.0 X-RAY
 2015-06-10 GLU A:24 E:24 108.0 0.568 T -53.9 -31.1 108.0 0.568 0.0 NAG
 3.143
 OE2
 N2
5j3h 4 P06213 99.68 0.0 X-RAY
 2016-06-15 GLU D:24 E:24 111.0 0.584 T -53.4 -32.0 111.0 0.584 0.0 NAG
NAG
FUC
 3.000
6.303
7.418
 OE2
OE2
OE2
 N2
C1
O5
6vep 5 P06213 99.68 0.0 X-RAY
 2020-06-03 GLU E:24 E:24 119.0 0.626 T -48.3 -27.0 119.0 0.626 0.0 NAG
NAG
FUC
 3.452
6.016
7.563
 OE1
OE1
OE1
 C1
O7
C1
GLU K:24 K:24 122.0 0.642 T -29.9 -48.5 NA NA NA
GLU Q:24 Q:24 123.0 0.647 T -31.5 -47.7 NA NA NA
GLU W:24 W:24 116.0 0.611 T -30.2 -49.3 NA NA NA
6veq 3 P06213 99.68 0.0 X-RAY
 2020-06-03 GLU C:24 E:24 113.0 0.595 T -66.0 -41.6 113.0 0.595 0.0 NAG
 2.730
 OE2
 N2
GLU G:24 K:24 119.0 0.626 T -65.1 -40.9 NA NA NA
7kd6 4 P06213 99.68 0.0 X-RAY
 2021-10-13 GLU D:24 E:24 120.0 0.632 T -47.8 -36.5 120.0 0.632 0.0 NAG
NAG
FUC
 3.412
6.659
7.096
 OE1
OE1
OE1
 C1
C1
C1
GLU I:24 K:24 113.0 0.595 T -49.3 -36.9 NA NA NA
GLU N:24 Q:24 117.0 0.616 T -49.4 -34.5 NA NA NA
GLU S:24 W:24 116.0 0.611 T -48.5 -34.0 NA NA NA
3w11 5 P06213 99.68 0.0 X-RAY
 2013-01-09 GLU E:24 E:24 109.0 0.574 S -50.3 -37.7 109.0 0.574 0.0 NAG
 2.835
 OE2
 N2
3w12 1 P06213 99.68 0.0 X-RAY
 2013-01-09 GLU A:24 E:24 115.0 0.605 T -54.5 -34.7 115.0 0.605 0.0 NAG
 3.033
 OE2
 N2
3w13 1 P06213 99.68 0.0 X-RAY
 2013-01-09 GLU A:24 E:24 115.0 0.605 T -52.3 -38.8 115.0 0.605 0.0 NAG
 2.982
 OE2
 N2

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06213-f1 1 P06213 100.0 0.0 GLU A:51 A:51 120.0 0.632 T -55.8 -33.1