Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 8464908 . G A CCDS12201.1:NM_004218.3:c.202Gct>Act_NP_004209.2:p.68A>T Homo sapiens RAB11B, member RAS oncogene family (RAB11B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4ojk 1 Q15907 100.0 3e-146 X-RAY
 2014-08-06 ALA A:63 A:68 37.0 0.322 T -67.7 -45.9 37.0 0.322 0.0 GDP
 5.560
 CB
 O2B
ALA B:63 NA:NA DO NA DO DO DO NA NA NA
5fbl 2 P62491 91.28 1e-145 X-RAY
 2016-12-28 ALA B:73 NA:NA DO NA DO DO DO NA NA NA
5fbq 2 P62491 91.28 1e-145 X-RAY
 2016-12-28 ALA B:73 NA:NA DO NA DO DO DO NA NA NA
2f9l 1 Q15907 99.49 2e-145 X-RAY
 2006-04-04 ALA A:62 A:68 23.0 0.2 S -104.3 29.9 23.0 0.2 0.0 MG
GDP
HOH
 5.554
7.397
3.646
 C
C
O
 MG
O3B
O
2f9m 1 Q15907 99.49 2e-145 X-RAY
 2006-04-04 ALA A:62 A:68 23.0 0.2 -67.7 139.4 23.0 0.2 0.0 MG
GNP
HOH
 4.963
3.401
2.904
 CA
CA
N
 MG
O3G
O
5fbr 2 P62491 90.83 2e-144 X-RAY
 2016-12-28 ALA B:73 B:68 16.0 0.139 -126.2 161.4 16.0 0.139 0.0 GSP
 4.007
 CA
 O2G
5fbv 2 P62491 90.83 2e-144 X-RAY
 2016-12-28 ALA B:73 B:68 11.0 0.096 -131.2 165.7 11.0 0.096 0.0 GSP
 3.653
 CA
 S1G
5fbw 2 P62491 90.83 2e-144 X-RAY
 2016-12-28 ALA B:73 NA:NA DO NA DO DO DO NA NA NA
4d0l 2 P62491 90.83 3e-144 X-RAY
 2014-05-28 ALA B:71 B:68 3.0 0.026 92.1 118.1 3.0 0.026 0.0 GSP
MG
HOH
 3.584
5.421
3.059
 CA
CA
N
 O2G
MG
O
ALA D:71 D:68 2.0 0.017 -102.5 133.2 NA NA NA
ALA F:71 F:68 2.0 0.017 -102.2 133.4 NA NA NA
4d0m 2 P62491 90.83 3e-144 X-RAY
 2014-05-28 ALA B:71 B:68 4.0 0.035 93.5 124.2 4.0 0.035 0.0 GSP
MG
 3.918
5.733
 CA
CA
 O2G
MG
ALA D:71 D:68 4.0 0.035 93.5 124.4 4.0 0.035 0.0 GSP
MG
 3.868
5.561
 CA
CA
 O2G
MG
ALA H:71 H:68 4.0 0.035 93.4 124.0 NA NA NA
ALA J:71 J:68 4.0 0.035 92.9 124.1 NA NA NA
ALA N:71 N:68 4.0 0.035 94.0 124.4 NA NA NA
ALA P:71 P:68 4.0 0.035 94.1 124.6 4.0 0.035 0.0 GSP
MG
 3.634
5.830
 CA
CA
 O2G
MG
ALA R:71 R:68 4.0 0.035 93.7 124.3 NA NA NA
ALA T:71 T:68 5.0 0.043 93.8 124.3 5.0 0.043 0.0 GSP
MG
 3.860
5.910
 CA
CA
 O2G
MG
ALA X:71 X:68 4.0 0.035 93.5 124.2 NA NA NA
ALA Z:71 Z:68 4.0 0.035 93.6 124.5 NA NA NA
ALA DA:71 d:68 4.0 0.035 94.0 124.8 NA NA NA
ALA HA:71 h:68 4.0 0.035 94.1 124.6 NA NA NA
5c46 2 P62491 90.83 3e-144 X-RAY
 2016-01-20 ALA B:71 F:68 2.0 0.017 -85.2 128.9 2.0 0.017 0.0 GSP
MG
HOH
 4.236
6.660
7.817
 C
CA
CB
 O2G
MG
O
5c4g 1 P62491 90.83 3e-144 X-RAY
 2016-01-20 ALA A:71 B:68 89.0 0.774 -126.9 360.0 89.0 0.774 0.0 MG
GDP
 5.942
6.058
 CB
CA
 MG
O3B
5euq 1 P62491 90.83 3e-144 X-RAY
 2016-02-24 ALA A:71 B:68 101.0 0.878 -120.8 360.0 101.0 0.878 0.0 GDP
 5.920
 CA
 O3B
6djl 1 P62491 90.83 3e-144 X-RAY
 2018-09-26 ALA A:71 A:68 7.0 0.061 64.0 34.9 7.0 0.061 0.0
ALA F:71 F:68 15.0 0.13 -65.1 -33.8 NA NA NA
ALA G:71 G:68 3.0 0.026 72.1 39.5 NA NA NA
ALA H:71 H:68 18.0 0.157 67.1 37.9 NA NA NA
4uj4 1 P62491 95.63 9e-128 X-RAY
 2015-08-12 ALA A:67 A:68 26.0 0.226 -61.0 126.3 NA NA NA
ALA D:67 D:68 26.0 0.226 -64.8 127.7 21.0 0.183 0.043 F:O75154:0.043
 GNP
MG
 3.837
5.158
 C
N
 O2G
MG
ALA G:67 G:68 25.0 0.217 -61.0 126.2 25.0 0.217 0.0 GNP
MG
 3.849
5.048
 C
CA
 O2G
MG
ALA J:67 J:68 23.0 0.2 -63.3 130.1 NA NA NA
4uj3 1 P62491 95.08 3e-127 X-RAY
 2015-08-12 ALA A:69 A:68 25.0 0.217 -61.5 127.3 25.0 0.217 0.0 GNP
MG
HOH
 4.135
5.687
5.452
 C
CA
CB
 O2G
MG
O
ALA D:69 D:68 27.0 0.235 -64.7 127.8 NA NA NA
ALA G:69 G:68 26.0 0.226 -61.2 126.4 NA NA NA
ALA J:69 J:68 25.0 0.217 -63.2 130.0 NA NA NA
ALA M:69 M:68 20.0 0.174 -64.4 130.4 NA NA NA
ALA P:69 P:68 25.0 0.217 -62.6 128.7 NA NA NA
ALA S:69 S:68 30.0 0.261 -64.5 129.2 NA NA NA
ALA V:69 V:68 39.0 0.339 -66.0 130.3 NA NA NA
5jcz 1 P62491 97.74 3e-126 X-RAY
 2016-09-28 ALA A:70 A:68 4.0 0.035 -74.7 149.4 4.0 0.035 0.0 MG
GDP
BEF
EDO
HOH
 5.048
5.471
3.236
3.788
2.987
 CA
CA
CA
O
N
 MG
O3B
F1
C1
O
ALA D:70 D:68 4.0 0.035 -75.7 145.8 NA NA NA
ALA F:70 I:68 30.0 0.261 -70.6 149.7 NA NA NA
4lwz 1 P62491 97.74 3e-126 X-RAY
 2013-11-20 ALA A:68 A:68 75.0 0.652 -63.6 360.0 75.0 0.652 0.0 GDP
MG
HOH
 6.636
6.019
4.260
 CA
CA
CA
 O3B
MG
O
ALA C:68 C:68 91.0 0.791 -46.9 360.0 NA NA NA
4lx0 1 P62491 97.74 3e-126 X-RAY
 2013-11-20 ALA A:68 A:68 1.0 0.009 -64.4 132.3 1.0 0.009 0.0 MG
BEF
GDP
GOL
HOH
 5.822
3.886
6.357
8.004
2.719
 CA
C
C
O
O
 MG
F1
O3B
O1
O
ALA C:68 C:68 2.0 0.017 -74.3 135.8 NA NA NA
4uj5 1 P62491 94.54 8e-126 X-RAY
 2015-08-12 ALA A:67 A:68 35.0 0.304 -62.0 143.5 35.0 0.304 0.0 GNP
MG
HOH
 3.684
5.291
4.073
 C
CA
O
 O2G
MG
O
ALA B:67 B:68 18.0 0.157 -62.5 144.2 NA NA NA
4c4p 1 P62491 97.69 2e-123 X-RAY
 2013-09-18 ALA A:68 A:68 15.0 0.13 -67.3 149.5 15.0 0.13 0.0 GNP
MG
HOH
 2.552
4.121
2.132
 HA
HA
H
 O2G
MG
O
6ixv 2 P62491 97.69 2e-123 X-RAY
 2019-03-20 ALA E:70 E:68 13.0 0.113 -70.9 -33.4 13.0 0.113 0.0 PO4
 8.525
 N
 O1
ALA F:70 F:68 8.0 0.07 -60.5 -56.8 NA NA NA
ALA G:70 G:68 8.0 0.07 -62.1 -53.3 NA NA NA
ALA H:70 H:68 8.0 0.07 -57.0 -57.2 NA NA NA
1oiv 1 P24410 97.69 8e-123 X-RAY
 2004-01-08 ALA A:86 A:68 22.0 0.191 -83.3 -14.7 22.0 0.191 0.0 GDP
HOH
 6.320
3.497
 CA
O
 O3B
O
ALA B:86 B:68 30.0 0.261 -84.5 -11.7 30.0 0.261 0.0 GDP
HOH
 6.314
3.621
 CA
O
 O3B
O
2gzd 1 P62491 97.11 4e-122 X-RAY
 2006-08-15 ALA A:68 A:68 11.0 0.096 -56.0 143.0 11.0 0.096 0.0 MG
GTP
HOH
 4.898
3.503
2.876
 CA
CA
N
 MG
O3G
O
ALA B:68 B:68 14.0 0.122 -58.2 156.8 14.0 0.122 0.0 MG
GTP
HOH
 4.751
3.257
2.909
 CA
CA
N
 MG
O3G
O
2gzh 1 P62491 97.11 4e-122 X-RAY
 2006-08-15 ALA A:68 A:68 17.0 0.148 -62.9 131.9 17.0 0.148 0.0 MG
MG
GTP
HOH
 5.541
4.219
3.742
2.796
 CA
O
CA
O
 MG
MG
O3G
O
1oiw 1 P24410 97.11 2e-121 X-RAY
 2004-01-08 ALA A:86 A:68 32.0 0.278 -65.3 143.2 32.0 0.278 0.0 GSP
MG
HOH
 3.667
5.253
2.940
 CA
CA
N
 O3G
MG
O
1oix 1 P24410 97.11 2e-121 X-RAY
 2005-01-25 ALA A:86 A:68 33.0 0.287 -64.0 136.2 33.0 0.287 0.0 GDP
PO4
MG
CL
HOH
 6.668
3.243
5.477
6.513
2.982
 CA
CB
CA
CB
N
 O3B
O2
MG
CL
O
2hv8 1 P62491 97.06 3e-119 X-RAY
 2006-11-21 ALA A:65 A:68 11.0 0.096 -61.5 143.3 9.0 0.078 0.018 B:O75154:0.017
 MG
SO4
GTP
HOH
 4.960
7.618
3.357
2.915
 CA
C
CA
O
 MG
O3
O3G
O
ALA C:65 B:68 11.0 0.096 -60.0 142.7 NA NA NA
ALA E:65 C:68 13.0 0.113 -58.6 141.4 NA NA NA
6iy1 3 P62491 97.62 4e-119 X-RAY
 2019-12-18 ALA F:63 F:68 48.0 0.417 -80.5 -15.1 NA NA NA
1yzk 1 P62491 97.62 1e-118 X-RAY
 2005-07-26 ALA A:77 A:68 22.0 0.191 -68.3 141.7 22.0 0.191 0.0 MG
GNP
HOH
 5.157
3.468
2.901
 CA
CA
N
 MG
O3G
O
6iy1 2 P62491 97.6 3e-118 X-RAY
 2019-12-18 ALA D:62 D:68 42.0 0.365 -79.0 -10.7 NA NA NA
5ez5 1 P62491 97.02 4e-118 X-RAY
 2016-12-07 ALA A:61 A:68 19.0 0.165 -57.1 141.4 19.0 0.165 0.0 MG
GTP
HOH
 4.977
3.330
6.681
 N
CA
CA
 MG
O3G
O
ALA B:61 B:68 16.0 0.139 -57.6 142.0 16.0 0.139 0.0 MG
GTP
HOH
 4.877
3.247
6.367
 N
CA
CA
 MG
O2G
O
2d7c 1 P62491 97.01 5e-117 X-RAY
 2006-09-26 ALA A:62 A:68 9.0 0.078 -61.8 146.6 9.0 0.078 0.0 MG
GTP
HOH
 5.102
3.353
2.970
 CA
CA
O
 MG
O3G
O
ALA B:62 B:68 15.0 0.13 -65.5 151.2 NA NA NA
6iy1 1 P62491 97.58 2e-116 X-RAY
 2019-12-18 ALA A:60 A:68 13.0 0.113 -68.2 -33.5 13.0 0.113 0.0 GDP
HOH
 6.070
2.411
 O
O
 O2B
O
ALA B:60 B:68 15.0 0.13 -76.5 -24.2 NA NA NA
ALA C:60 C:68 13.0 0.113 -79.6 -21.8 NA NA NA
ALA E:60 E:68 49.0 0.426 -84.2 -1.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15907-f1 1 Q15907 100.0 1e-164 ALA A:68 A:68 1.0 0.009 -55.2 129.0
af-p62491-f1 1 P62491 91.28 6e-146 ALA A:68 A:68 1.0 0.009 -61.2 128.5