Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 9946061 . G A CCDS12220.1:NM_006221.3:c.41cGc>cAc_NP_006212.1:p.14R>H Homo sapiens peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (PIN1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1pin 1 Q13526 100.0 9e-121 X-RAY
 1998-10-14 ARG A:14 A:14 108.0 0.48 E -130.3 174.7 108.0 0.48 0.0 1PG
HOH
 7.507
2.847
 CB
NH2
 C6
O
7sa5 1 Q13526 100.0 9e-121 NMR
 2021-10-20 ARG A:14 A:14 123.0 0.547 E -140.0 171.0 123.0 0.547 0.0
1f8a 1 Q13526 100.0 2e-120 X-RAY
 2000-08-23 ARG A:18 B:18 113.0 0.502 E -146.3 173.1 57.0 0.253 0.249 B:None:0.249
 HOH
 3.378
 CB
 O
2zr4 1 Q13526 99.39 2e-120 X-RAY
 2009-08-25 ARG A:14 A:14 106.0 0.471 E -130.0 175.8 106.0 0.471 0.0 1PG
HOH
 7.523
2.640
 CB
NH2
 O1
O
2zr5 1 Q13526 99.39 6e-120 X-RAY
 2009-08-25 ARG A:14 A:14 124.0 0.551 -132.8 -149.9 124.0 0.551 0.0 1PG
HOH
 7.563
2.729
 CB
O
 O5
O
2zqt 1 Q13526 99.39 7e-120 X-RAY
 2009-08-25 ARG A:14 A:14 108.0 0.48 E -130.6 169.5 108.0 0.48 0.0 1PG
HOH
 7.390
3.106
 CB
NH2
 C6
O
2zr6 1 Q13526 99.39 8e-120 X-RAY
 2009-08-25 ALA A:14 A:14 41.0 0.357 E 162.5 -156.8 41.0 0.357 0.0 1PG
HOH
 7.178
3.286
 O
CB
 C9
O
3oob 1 Q13526 99.39 8e-120 X-RAY
 2011-08-17 ALA A:14 A:14 23.0 0.2 E -141.0 176.6 23.0 0.2 0.0 PE4
KDH
HOH
 7.364
6.342
5.945
 CB
CB
N
 C15
O7
O
3wh0 1 Q13526 99.39 8e-120 X-RAY
 2014-10-15 ALA A:14 A:14 19.0 0.165 E -134.0 174.0 19.0 0.165 0.0 O4B
HOH
 7.263
3.425
 CB
CB
 CAJ
O
5uy9 1 Q13526 99.39 8e-120 X-RAY
 2017-04-26 ALA A:14 A:14 24.0 0.209 E -139.3 175.9 24.0 0.209 0.0 PE4
HOH
 7.369
6.809
 CB
CB
 C5
O
2zqv 1 Q13526 99.39 1e-119 X-RAY
 2009-08-25 ARG A:14 A:14 21.0 NA E -146.6 -178.9 21.0 NA NA HOH
 3.391
 CB
 O
3tc5 1 Q13526 99.39 1e-119 X-RAY
 2011-08-31 ALA A:17 A:14 20.0 0.174 E -138.6 170.1 20.0 0.174 0.0 P6G
HOH
 7.094
3.670
 CB
CB
 C3
O
6o33 1 Q13526 98.77 1e-119 X-RAY
 2020-02-26 ARG A:14 A:14 107.0 0.476 E -123.0 170.5 107.0 0.476 0.0 HOH
 4.880
 N
 O
2zqs 1 Q13526 99.39 2e-119 X-RAY
 2009-08-25 ARG A:14 A:14 110.0 0.489 E -132.7 178.3 110.0 0.489 0.0 1PG
HOH
 7.678
3.286
 CB
NH1
 C6
O
2itk 1 Q13526 99.39 2e-119 X-RAY
 2007-05-22 ALA A:18 A:14 22.0 0.191 E -138.6 177.8 22.0 0.191 0.0 PE4
HOH
 7.223
3.773
 CB
CB
 C5
O
2q5a 1 Q13526 99.39 2e-119 X-RAY
 2007-06-26 ALA A:18 A:14 24.0 0.209 E -138.8 178.5 24.0 0.209 0.0 16P
HOH
 7.076
3.825
 CB
CB
 C13
O
2xp3 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ALA A:18 A:14 20.0 0.174 E -138.8 170.5 20.0 0.174 0.0 12P
HOH
 7.159
5.995
 CB
CB
 C23
O
2xp4 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ALA A:18 A:14 22.0 0.191 E -142.3 172.4 22.0 0.191 0.0 12P
HOH
 7.354
3.384
 CB
O
 O19
O
2xp5 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ALA A:18 A:14 30.0 0.261 E -135.6 175.0 30.0 0.261 0.0 12P
HOH
 7.290
5.975
 CB
CB
 C15
O
2xp7 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ALA A:18 A:14 25.0 0.217 E -141.1 -177.0 25.0 0.217 0.0 12P
HOH
 6.980
3.518
 CB
O
 C20
O
2xp8 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ALA A:18 A:14 24.0 0.209 E -151.5 162.1 24.0 0.209 0.0 12P
HOH
 6.557
8.198
 CB
O
 C26
O
2xp9 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ALA A:18 A:14 20.0 0.174 E -142.4 175.2 20.0 0.174 0.0 12P
HOH
 7.162
4.046
 CB
CB
 C35
O
2xpa 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ALA A:18 A:14 21.0 0.183 E -143.7 166.3 21.0 0.183 0.0 12P
HOH
 7.148
3.304
 CB
CB
 O34
O
2xpb 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ALA A:18 A:14 29.0 0.252 E -151.8 171.2 29.0 0.252 0.0 12P
HOH
 7.586
5.775
 O
CB
 C35
O
3kab 1 Q13526 99.39 2e-119 X-RAY
 2009-12-22 ALA A:18 A:14 22.0 0.191 E -127.9 170.7 22.0 0.191 0.0 12P
HOH
 6.915
7.226
 CB
O
 O16
O
3kag 1 Q13526 99.39 2e-119 X-RAY
 2009-12-22 ALA A:18 A:14 24.0 0.209 E -143.9 165.8 24.0 0.209 0.0 12P
HOH
 6.959
4.052
 CB
C
 C18
O
3kah 1 Q13526 99.39 2e-119 X-RAY
 2009-12-22 ALA A:18 A:14 28.0 0.243 E -150.2 179.7 28.0 0.243 0.0 12P
HOH
 7.699
3.643
 CB
CA
 C20
O
3kai 1 Q13526 99.39 2e-119 X-RAY
 2009-12-22 ALA A:18 A:14 17.0 0.148 E -133.6 179.1 17.0 0.148 0.0 12P
HOH
 6.983
3.722
 CB
O
 C15
O
3kce 1 Q13526 99.39 2e-119 X-RAY
 2009-12-22 ALA A:18 A:14 23.0 0.2 E -148.8 173.9 23.0 0.2 0.0 12P
HOH
 7.414
7.046
 CB
O
 C33
O
3ntp 1 Q13526 99.39 2e-119 X-RAY
 2012-01-04 ALA A:18 A:14 24.0 0.209 E -138.9 173.6 24.0 0.209 0.0 PE8
HOH
 7.335
7.258
 CB
O
 C8
O
3odk 1 Q13526 99.39 2e-119 X-RAY
 2010-10-27 ALA A:18 A:14 30.0 0.261 E -165.2 -171.5 30.0 0.261 0.0 PE4
HOH
 7.904
6.592
 CB
CB
 O8
O
6vaj 1 Q13526 98.77 2e-119 X-RAY
 2020-12-30 ARG A:29 A:14 116.0 0.516 E -134.5 175.1 116.0 0.516 0.0 PG4
HOH
 6.674
4.637
 CB
N
 H52
O
4u84 1 Q13526 99.39 2e-119 X-RAY
 2015-04-08 ALA A:32 A:14 21.0 0.183 E -142.6 173.7 21.0 0.183 0.0 15P
HOH
 6.971
3.684
 CB
CB
 O1
O
4u85 1 Q13526 99.39 2e-119 X-RAY
 2015-04-08 ALA A:32 A:14 22.0 0.191 E -144.4 175.8 22.0 0.191 0.0 HOH
 3.908
 CB
 O
4u86 1 Q13526 99.39 2e-119 X-RAY
 2015-04-08 ALA A:32 A:14 24.0 0.209 E -146.5 167.3 24.0 0.209 0.0 1PG
HOH
 7.045
3.739
 CB
CB
 O5
O
2zqu 1 Q13526 99.39 3e-119 X-RAY
 2009-08-25 ARG A:14 A:14 115.0 0.511 E -136.4 -176.7 115.0 0.511 0.0 HOH
 3.304
 NH1
 O
6o34 1 Q13526 98.16 7e-119 X-RAY
 2020-02-26 ARG A:14 A:14 121.0 0.538 E -129.2 175.2 121.0 0.538 0.0 2PE
HOH
 7.309
2.835
 CB
NH1
 C8
O
2xp6 1 Q13526 98.77 9e-119 X-RAY
 2011-01-12 ALA A:18 A:14 26.0 0.226 E -132.2 167.4 26.0 0.226 0.0 12P
HOH
 7.333
3.927
 CB
C
 C17
O
3kad 1 Q13526 98.77 9e-119 X-RAY
 2009-12-22 ALA A:18 A:14 23.0 0.2 E -145.9 172.0 23.0 0.2 0.0 12P
HOH
 7.600
3.465
 CB
CB
 C18
O
3kaf 1 Q13526 98.77 9e-119 X-RAY
 2009-12-22 ALA A:18 A:14 17.0 0.148 E -141.3 165.2 17.0 0.148 0.0 HOH
 8.411
 CB
 O
2f21 1 Q13526 98.16 4e-117 X-RAY
 2006-06-20 ARG A:14 A:14 131.0 0.582 E -131.5 175.7 131.0 0.582 0.0 1PE
HOH
 7.284
3.168
 CB
NH2
 C24
O
1zcn 1 Q13526 98.16 6e-117 X-RAY
 2006-06-20 ARG A:14 A:14 113.0 0.502 E -129.2 -178.9 113.0 0.502 0.0 1PE
HOH
 7.382
4.093
 CB
NH1
 C25
O
3tcz 1 Q13526 99.37 1e-115 X-RAY
 2012-06-20 ALA A:9 A:14 18.0 0.157 E -132.3 166.3 18.0 0.157 0.0 PE4
HOH
 7.128
3.166
 CB
CB
 C3
O
3tdb 1 Q13526 99.37 1e-115 X-RAY
 2012-06-27 ALA A:9 A:14 23.0 0.2 E -133.0 171.1 23.0 0.2 0.0 PE4
HOH
 7.031
6.974
 CB
CB
 C3
O
4qib 1 Q13526 99.36 4e-115 X-RAY
 2015-02-04 ALA A:10 A:14 24.0 0.209 E -141.5 178.0 24.0 0.209 0.0 PE4
HOH
 5.681
2.514
 HB3
HB1
 H42
O
2m8i 1 Q13526 100.0 3e-23 NMR
 2014-04-09 ARG A:18 A:18 107.0 0.476 E -124.2 -177.2 107.0 0.476 0.0
2m8j 1 Q13526 97.44 1e-22 NMR
 2014-04-09 ARG A:18 A:18 98.0 0.436 E -124.5 -177.7 98.0 0.436 0.0
2lb3 1 Q13526 100.0 1e-20 NMR
 2011-07-06 ARG A:9 A:18 128.0 0.569 E -150.7 150.0 97.0 0.431 0.138 B:Q15796:0.138
4gwt 1 Q13526 100.0 3e-19 X-RAY
 2013-10-16 ARG A:11 A:14 95.0 0.422 E -129.9 172.5 95.0 0.422 0.0 HOH
 3.293
 O
 O
4gwv 1 Q13526 100.0 3e-19 X-RAY
 2013-10-16 ARG A:11 A:14 86.0 0.382 E -126.9 173.0 86.0 0.382 0.0 FLC
HOH
 5.399
4.061
 NH2
NH2
 OA2
O
5vtk 1 Q13526 100.0 3e-19 X-RAY
 2018-02-21 ARG A:9 A:14 97.0 0.431 E -131.9 152.1 97.0 0.431 0.0 CL
CL
CL
CL
HOH
 3.836
5.582
8.450
9.805
2.434
 CA
CB
O
NH2
NH2
 CL
CL
CL
CL
O
5b3z 1 Q13526,P0AEX9 90.0 1e-18 X-RAY
 2016-10-26 ARG A:11 A:11 76.0 0.338 E -134.9 172.4 76.0 0.338 0.0 HOH
 3.617
 CB
 O
ARG B:11 B:11 80.0 0.356 E -129.2 174.2 NA NA NA
ARG C:11 C:11 74.0 0.329 E -138.1 167.0 NA NA NA
ARG D:11 D:11 79.0 0.351 E -134.2 174.0 NA NA NA
5vtj 1 Q13526 97.06 1e-18 X-RAY
 2018-02-21 ARG A:9 A:14 73.0 0.324 E -128.9 160.9 73.0 0.324 0.0 SO4
SO4
HOH
 7.413
7.127
2.847
 C
N
NH1
 O4
O1
O
2n1o 1 Q13526 100.0 2e-18 NMR
 2015-10-28 ARG A:8 A:14 104.0 0.462 E -125.7 150.6 96.0 0.427 0.035 B:Q9BZB8:0.036
6svc 1 Q13526 94.12 1e-17 NMR
 2020-09-30 ARG A:10 A:14 117.0 0.52 E -119.5 166.7 117.0 0.52 0.0
6sve 1 Q13526 94.12 1e-17 NMR
 2020-10-07 ARG A:10 A:14 147.0 0.653 E -135.6 168.3 147.0 0.653 0.0
6svh 1 Q13526 94.12 1e-17 NMR
 2020-09-30 ARG A:10 A:14 113.0 0.502 E -116.1 156.0 113.0 0.502 0.0
2m9i 1 Q13526 88.24 7e-16 NMR
 2013-06-26 ARG A:9 A:9 90.0 0.4 E -145.2 174.4 90.0 0.4 0.0
2m9j 1 Q13526 88.24 7e-16 NMR
 2013-06-26 ARG A:9 A:9 62.0 0.276 E -144.5 151.4 62.0 0.276 0.0 NAG
 8.395
 HG3
 H5
5vti 1 Q13526 91.18 2e-15 X-RAY
 2018-02-21 ARG A:9 A:14 81.0 0.36 E -127.8 174.1 81.0 0.36 0.0 HOH
 2.717
 NH2
 O
2m9e 1 Q13526 82.35 4e-13 NMR
 2013-06-26 ARG A:9 A:9 103.0 0.458 E -144.8 -175.0 103.0 0.458 0.0
2m9f 1 Q13526 82.35 4e-13 NMR
 2013-06-26 ARG A:9 A:9 71.0 0.316 E -143.6 -179.8 71.0 0.316 0.0 NAG
 8.768
 HB2
 H5
2nc3 1 ? 82.35 4e-13 NMR
 2016-06-08 ARG A:9 A:9 134.0 0.596 E -142.7 165.3 134.0 0.596 0.0 ALL
 8.967
 O
 H1
2nc4 1 ? 82.35 4e-13 NMR
 2016-06-08 ARG A:9 A:9 124.0 0.551 E -145.4 168.5 124.0 0.551 0.0 GAL
 8.839
 HG2
 H5
2nc5 1 ? 82.35 4e-13 NMR
 2016-06-08 ARG A:9 A:9 114.0 0.507 E -143.1 162.6 114.0 0.507 0.0 XYP
 8.872
 O
 H52
2nc6 1 ? 82.35 4e-13 NMR
 2016-06-08 ARG A:9 A:9 85.0 0.378 E -139.6 170.8 85.0 0.378 0.0 4N2
 8.304
 HB3
 HO3
5b3y 1 Q13526,P0AEX9 100.0 1e-05 X-RAY
 2016-10-26 ARG A:11 A:11 199.0 0.884 H -59.9 -20.9 199.0 0.884 0.0 HOH
 6.535
 O
 O
5bmy 1 Q13526,P0AEY0 100.0 0.0005 X-RAY
 2016-10-26 ARG A:11 A:11 56.0 0.249 H -64.1 -36.1 56.0 0.249 0.0 HOH
 2.811
 O
 O
5b3w 1 Q13526,P0AEX9 81.25 1.0 X-RAY
 2016-10-26 ARG A:11 A:11 227.0 1.0 H -61.7 -41.0 227.0 1.0 0.0 HOH
 3.010
 NH2
 O
ARG B:11 B:11 219.0 0.973 H -59.1 -38.6 NA NA NA
5b3x 1 Q13526,P0AEX9 81.25 1.0 X-RAY
 2016-10-26 ARG A:11 A:11 43.0 0.191 G -73.6 -4.3 43.0 0.191 0.0 HOH
 9.536
 CD
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q13526-f1 1 Q13526 100.0 4e-121 ARG A:14 A:14 93.0 0.413 E -122.7 164.3
af-o15428-f1 1 O15428 90.48 7e-35 ARG A:14 A:14 97.0 0.431 E -125.4 162.4