Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 9949166 | . | G | A | CCDS12220.1:NM_006221.3:c.113aGc>aAc_NP_006212.1:p.38S>N | Homo sapiens peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (PIN1), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1pin | 1 | Q13526 | 100.0 | 9e-121 |
X-RAY |
1998-10-14 | SER | A:38 | A:38 | 31.0 | 0.27 | -165.3 | 170.3 | 5.0 | 0.043 | 0.227 |
A:Q13526:0.226 |
1PG HOH |
9.121 2.841 |
O O |
C1 O |
||
| 7sa5 | 1 | Q13526 | 100.0 | 9e-121 |
NMR |
2021-10-20 | SER | A:38 | A:38 | 66.0 | 0.574 | 55.7 | 25.7 | 66.0 | 0.574 | 0.0 | |||||||
| 1f8a | 1 | Q13526 | 100.0 | 2e-120 |
X-RAY |
2000-08-23 | SER | A:42 | B:42 | 44.0 | 0.383 | 115.4 | 360.0 | 44.0 | 0.383 | 0.0 |
HOH |
5.527 |
N |
O |
|||
| 2zr4 | 1 | Q13526 | 99.39 | 2e-120 |
X-RAY |
2009-08-25 | SER | A:38 | A:38 | 27.0 | 0.235 | -151.0 | 154.1 | 27.0 | 0.235 | 0.0 |
HOH |
2.902 |
O |
O |
|||
| 2zr5 | 1 | Q13526 | 99.39 | 6e-120 |
X-RAY |
2009-08-25 | SER | A:38 | A:38 | 38.0 | 0.33 | -129.5 | -174.2 | 38.0 | 0.33 | 0.0 |
HOH |
2.728 |
O |
O |
|||
| 2zqt | 1 | Q13526 | 99.39 | 7e-120 |
X-RAY |
2009-08-25 | SER | A:38 | A:38 | 26.0 | 0.226 | -149.1 | 157.6 | 26.0 | 0.226 | 0.0 |
HOH |
3.587 |
CB |
O |
|||
| 2zr6 | 1 | Q13526 | 99.39 | 8e-120 |
X-RAY |
2009-08-25 | SER | A:38 | A:38 | 30.0 | 0.261 | -126.5 | 157.3 | 30.0 | 0.261 | 0.0 |
HOH |
4.518 |
CA |
O |
|||
| 3oob | 1 | Q13526 | 99.39 | 8e-120 |
X-RAY |
2011-08-17 | SER | A:38 | A:38 | 130.0 | 1.0 | -58.5 | 360.0 | 130.0 | 1.0 | 0.0 |
PE4 HOH |
9.692 3.238 |
N N |
C2 O |
|||
| 3wh0 | 1 | Q13526 | 99.39 | 8e-120 |
X-RAY |
2014-10-15 | SER | A:38 | A:38 | 135.0 | 1.0 | -99.4 | 360.0 | 135.0 | 1.0 | 0.0 |
HOH |
2.921 |
N |
O |
|||
| 5uy9 | 1 | Q13526 | 99.39 | 8e-120 |
X-RAY |
2017-04-26 | SER | A:38 | A:38 | 141.0 | 1.0 | -142.3 | 360.0 | 141.0 | 1.0 | 0.0 |
HOH |
7.844 |
N |
O |
|||
| 2zqv | 1 | Q13526 | 99.39 | 1e-119 |
X-RAY |
2009-08-25 | SER | A:38 | A:38 | 61.0 | 0.53 | -174.3 | 136.8 | 61.0 | 0.53 | 0.0 |
HOH |
2.538 |
OG |
O |
|||
| 3tc5 | 1 | Q13526 | 99.39 | 1e-119 |
X-RAY |
2011-08-31 | SER | A:41 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6o33 | 1 | Q13526 | 98.77 | 1e-119 |
X-RAY |
2020-02-26 | SER | A:38 | A:38 | 35.0 | 0.304 | -159.2 | 152.4 | 35.0 | 0.304 | 0.0 |
SO4 HOH |
9.784 4.834 |
CB CB |
O2 O |
|||
| 2zqs | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2009-08-25 | SER | A:38 | A:38 | 24.0 | 0.209 | -154.1 | 149.6 | 24.0 | 0.209 | 0.0 |
HOH |
3.120 |
O |
O |
|||
| 2itk | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2007-05-22 | SER | A:42 | A:38 | 131.0 | 1.0 | -58.7 | 360.0 | 131.0 | 1.0 | 0.0 |
HOH |
5.294 |
O |
O |
|||
| 2q5a | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2007-06-26 | SER | A:42 | A:38 | 121.0 | 1.0 | -80.5 | 360.0 | 121.0 | 1.0 | 0.0 |
HOH |
3.789 |
O |
O |
|||
| 2xp3 | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2011-01-12 | SER | A:42 | A:38 | 125.0 | 1.0 | 21.0 | 360.0 | 125.0 | 1.0 | 0.0 |
HOH |
2.116 |
CA |
O |
|||
| 2xp4 | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2011-01-12 | SER | A:42 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 2xp5 | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2011-01-12 | SER | A:42 | A:38 | 136.0 | 1.0 | 149.8 | 360.0 | 136.0 | 1.0 | 0.0 |
HOH |
4.647 |
N |
O |
|||
| 2xp7 | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2011-01-12 | SER | A:42 | A:38 | 124.0 | 1.0 | 41.3 | 360.0 | 124.0 | 1.0 | 0.0 |
HOH |
2.597 |
OG |
O |
|||
| 2xp8 | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2011-01-12 | SER | A:42 | A:38 | 151.0 | 1.0 | 75.9 | 360.0 | 151.0 | 1.0 | 0.0 |
HOH |
2.717 |
N |
O |
|||
| 2xp9 | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2011-01-12 | SER | A:42 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 2xpa | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2011-01-12 | SER | A:42 | A:38 | 121.0 | 1.0 | -94.8 | -65.0 | 121.0 | 1.0 | 0.0 |
HOH |
2.520 |
O |
O |
|||
| 2xpb | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2011-01-12 | SER | A:42 | A:38 | 89.0 | 0.774 | -111.7 | -43.9 | 89.0 | 0.774 | 0.0 |
HOH |
3.387 |
O |
O |
|||
| 3kab | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2009-12-22 | SER | A:42 | A:38 | 125.0 | 1.0 | 30.0 | 360.0 | 125.0 | 1.0 | 0.0 |
HOH |
2.584 |
OG |
O |
|||
| 3kag | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2009-12-22 | SER | A:42 | A:38 | 125.0 | 1.0 | -62.9 | 360.0 | 125.0 | 1.0 | 0.0 |
HOH |
4.282 |
OG |
O |
|||
| 3kah | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2009-12-22 | SER | A:42 | A:38 | 142.0 | 1.0 | 161.2 | 360.0 | 142.0 | 1.0 | 0.0 |
HOH |
3.195 |
O |
O |
|||
| 3kai | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2009-12-22 | SER | A:42 | A:38 | 108.0 | 0.939 | 104.1 | 360.0 | 108.0 | 0.939 | 0.0 |
HOH |
2.647 |
CB |
O |
|||
| 3kce | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2009-12-22 | SER | A:42 | A:38 | 104.0 | NA | -63.4 | 360.0 | 104.0 | NA | NA |
12P HOH |
9.505 6.695 |
N N |
O13 O |
|||
| 3ntp | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2012-01-04 | SER | A:42 | A:38 | 118.0 | 1.0 | 93.8 | 360.0 | 118.0 | 1.0 | 0.0 |
HOH |
2.559 |
N |
O |
|||
| 3odk | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2010-10-27 | SER | A:42 | A:38 | 127.0 | 1.0 | 3.2 | 360.0 | 127.0 | 1.0 | 0.0 |
PE4 HOH |
9.341 3.912 |
N N |
C2 O |
|||
| 6vaj | 1 | Q13526 | 98.77 | 2e-119 |
X-RAY |
2020-12-30 | SER | A:53 | A:38 | 34.0 | 0.296 | -150.8 | 153.6 | 34.0 | 0.296 | 0.0 |
HOH |
4.819 |
O |
O |
|||
| 4u84 | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2015-04-08 | SER | A:56 | A:38 | 145.0 | 1.0 | -142.3 | 360.0 | 145.0 | 1.0 | 0.0 |
HOH |
4.272 |
N |
O |
|||
| 4u85 | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2015-04-08 | SER | A:56 | A:38 | 136.0 | 1.0 | 146.8 | 360.0 | 136.0 | 1.0 | 0.0 |
HOH |
5.522 |
OG |
O |
|||
| 4u86 | 1 | Q13526 | 99.39 | 2e-119 |
X-RAY |
2015-04-08 | SER | A:56 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 2zqu | 1 | Q13526 | 99.39 | 3e-119 |
X-RAY |
2009-08-25 | SER | A:38 | A:38 | 33.0 | 0.287 | -178.2 | 158.3 | 33.0 | 0.287 | 0.0 |
HOH |
6.392 |
C |
O |
|||
| 6o34 | 1 | Q13526 | 98.16 | 7e-119 |
X-RAY |
2020-02-26 | SER | A:38 | A:38 | 32.0 | 0.278 | -153.5 | 150.3 | 32.0 | 0.278 | 0.0 |
HOH |
4.424 |
OG |
O |
|||
| 2xp6 | 1 | Q13526 | 98.77 | 9e-119 |
X-RAY |
2011-01-12 | SER | A:42 | A:38 | 114.0 | 0.991 | -165.5 | 360.0 | 114.0 | 0.991 | 0.0 |
HOH |
6.429 |
CB |
O |
|||
| 3kad | 1 | Q13526 | 98.77 | 9e-119 |
X-RAY |
2009-12-22 | SER | A:42 | A:38 | 129.0 | 1.0 | 127.5 | 360.0 | 129.0 | 1.0 | 0.0 |
HOH |
2.888 |
O |
O |
|||
| 3kaf | 1 | Q13526 | 98.77 | 9e-119 |
X-RAY |
2009-12-22 | SER | A:42 | A:38 | 142.0 | 1.0 | 173.5 | 360.0 | 142.0 | 1.0 | 0.0 |
HOH |
3.374 |
CB |
O |
|||
| 2f21 | 1 | Q13526 | 98.16 | 4e-117 |
X-RAY |
2006-06-20 | SER | A:37 | A:38 | 29.0 | 0.252 | -158.1 | 174.5 | 29.0 | 0.252 | 0.0 |
HOH |
3.472 |
CB |
O |
|||
| 1zcn | 1 | Q13526 | 98.16 | 6e-117 |
X-RAY |
2006-06-20 | SER | A:36 | A:38 | 92.0 | 0.8 | -138.0 | 360.0 | 92.0 | 0.8 | 0.0 |
HOH |
2.840 |
C |
O |
|||
| 3tcz | 1 | Q13526 | 99.37 | 1e-115 |
X-RAY |
2012-06-20 | SER | A:33 | A:38 | 142.0 | 1.0 | 177.1 | 360.0 | 142.0 | 1.0 | 0.0 |
HOH |
2.886 |
OG |
O |
|||
| 3tdb | 1 | Q13526 | 99.37 | 1e-115 |
X-RAY |
2012-06-27 | SER | A:33 | A:38 | 142.0 | 1.0 | -166.9 | 360.0 | 142.0 | 1.0 | 0.0 |
HOH |
2.535 |
CA |
O |
|||
| 4qib | 1 | Q13526 | 99.36 | 4e-115 |
X-RAY |
2015-02-04 | SER | A:34 | A:38 | 128.0 | 1.0 | -70.5 | 360.0 | 128.0 | 1.0 | 0.0 |
SO4 HOH |
7.261 3.633 |
HG H |
O4 O |
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| 2m8i | 1 | Q13526 | 100.0 | 3e-23 |
NMR |
2014-04-09 | SER | A:42 | A:42 | 128.0 | 1.0 | -152.2 | 75.5 | 128.0 | 1.0 | 0.0 | |||||||
| 2m8j | 1 | Q13526 | 97.44 | 1e-22 |
NMR |
2014-04-09 | SER | A:42 | A:42 | 112.0 | 0.974 | -149.9 | 116.3 | 112.0 | 0.974 | 0.0 | |||||||
| 2lb3 | 1 | Q13526 | 100.0 | 1e-20 |
NMR |
2011-07-06 | SER | A:33 | A:42 | 88.0 | 0.765 | T | -106.4 | 6.0 | 88.0 | 0.765 | 0.0 | ||||||
| 4gwt | 1 | Q13526 | 100.0 | 3e-19 |
X-RAY |
2013-10-16 | SER | A:35 | A:38 | 161.0 | 1.0 | 152.6 | 360.0 | 161.0 | 1.0 | 0.0 |
HOH |
6.039 |
CA |
O |
|||
| 4gwv | 1 | Q13526 | 100.0 | 3e-19 |
X-RAY |
2013-10-16 | SER | A:35 | A:38 | 153.0 | 1.0 | -3.0 | 360.0 | 153.0 | 1.0 | 0.0 | |||||||
| 5vtk | 1 | Q13526 | 100.0 | 3e-19 |
X-RAY |
2018-02-21 | SER | A:33 | A:38 | 146.0 | 1.0 | -85.5 | 360.0 | 146.0 | 1.0 | 0.0 |
HOH |
3.805 |
CA |
O |
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| 5b3z | 1 | Q13526,P0AEX9 | 90.0 | 1e-18 |
X-RAY |
2016-10-26 | SER | A:35 | A:35 | 6.0 | 0.052 | T | -85.5 | 156.2 | 6.0 | 0.052 | 0.0 |
HOH |
3.704 |
CA |
O |
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| SER | B:35 | B:35 | 8.0 | 0.07 | S | -112.8 | 162.2 | NA | NA | NA | |||||||||||||
| SER | C:35 | C:35 | 11.0 | 0.096 | S | -142.9 | 168.3 | NA | NA | NA | |||||||||||||
| SER | D:35 | D:35 | 17.0 | 0.148 | S | -132.1 | 158.7 | NA | NA | NA | |||||||||||||
| 5vtj | 1 | Q13526 | 97.06 | 1e-18 |
X-RAY |
2018-02-21 | SER | A:33 | A:38 | 156.0 | 1.0 | -74.1 | 360.0 | 156.0 | 1.0 | 0.0 |
SO4 HOH |
9.344 4.637 |
N N |
O3 O |
|||
| 2n1o | 1 | Q13526 | 100.0 | 2e-18 |
NMR |
2015-10-28 | SER | A:32 | A:38 | 78.0 | 0.678 | T | -91.3 | -1.4 | 78.0 | 0.678 | 0.0 | ||||||
| 6svc | 1 | Q13526 | 94.12 | 1e-17 |
NMR |
2020-09-30 | SER | A:34 | A:38 | 117.0 | 1.0 | -114.3 | 149.1 | 117.0 | 1.0 | 0.0 | |||||||
| 6sve | 1 | Q13526 | 94.12 | 1e-17 |
NMR |
2020-10-07 | SER | A:34 | A:38 | 101.0 | 0.878 | -98.1 | 46.1 | 101.0 | 0.878 | 0.0 | |||||||
| 6svh | 1 | Q13526 | 94.12 | 1e-17 |
NMR |
2020-09-30 | SER | A:34 | A:38 | 119.0 | 1.0 | -73.2 | -58.7 | 119.0 | 1.0 | 0.0 | |||||||
| 2m9i | 1 | Q13526 | 88.24 | 7e-16 |
NMR |
2013-06-26 | SER | A:33 | A:33 | 83.0 | 0.722 | -73.5 | 59.8 | 83.0 | 0.722 | 0.0 | |||||||
| 2m9j | 1 | Q13526 | 88.24 | 7e-16 |
NMR |
2013-06-26 | SER | A:33 | A:33 | 86.0 | 0.748 | -114.1 | -82.1 | 86.0 | 0.748 | 0.0 | |||||||
| 5vti | 1 | Q13526 | 91.18 | 2e-15 |
X-RAY |
2018-02-21 | SER | A:31 | A:36 | 150.0 | 1.0 | -75.6 | 360.0 | 150.0 | 1.0 | 0.0 |
CL HOH |
6.234 3.248 |
O C |
CL O |
|||
| 2m9e | 1 | Q13526 | 82.35 | 4e-13 |
NMR |
2013-06-26 | SER | A:32 | A:32 | 99.0 | 0.861 | 57.7 | 51.6 | 99.0 | 0.861 | 0.0 | |||||||
| 2m9f | 1 | Q13526 | 82.35 | 4e-13 |
NMR |
2013-06-26 | SER | A:32 | A:32 | 123.0 | 1.0 | -61.2 | -23.4 | 123.0 | 1.0 | 0.0 | |||||||
| 2nc3 | 1 | ? | 82.35 | 4e-13 |
NMR |
2016-06-08 | SER | A:32 | A:32 | 90.0 | 0.783 | -146.9 | 154.0 | 90.0 | 0.783 | 0.0 | |||||||
| 2nc4 | 1 | ? | 82.35 | 4e-13 |
NMR |
2016-06-08 | SER | A:32 | A:32 | 119.0 | 1.0 | -133.5 | 10.0 | 119.0 | 1.0 | 0.0 | |||||||
| 2nc5 | 1 | ? | 82.35 | 4e-13 |
NMR |
2016-06-08 | SER | A:32 | A:32 | 124.0 | 1.0 | -85.6 | -22.8 | 124.0 | 1.0 | 0.0 | |||||||
| 2nc6 | 1 | ? | 82.35 | 4e-13 |
NMR |
2016-06-08 | SER | A:32 | A:32 | 97.0 | 0.843 | T | 49.4 | 48.3 | 97.0 | 0.843 | 0.0 | ||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q13526-f1 | 1 | Q13526 | 100.0 | 4e-121 | SER | A:38 | A:38 | 70.0 | 0.609 | -69.9 | 124.4 | ||
| af-o15428-f1 | 1 | O15428 | 90.48 | 7e-35 | SER | A:38 | A:38 | 69.0 | 0.6 | -79.4 | 140.1 | ||