Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 9958804 . G A CCDS12220.1:NM_006221.3:c.370Gcc>Acc_NP_006212.1:p.124A>T Homo sapiens peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (PIN1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1pin 1 Q13526 100.0 9e-121 X-RAY
 1998-10-14 ALA A:124 A:124 42.0 0.365 E -83.7 150.4 42.0 0.365 0.0 PRO
HOH
 7.654
2.757
 O
O
 CG
O
7sa5 1 Q13526 100.0 9e-121 NMR
 2021-10-20 ALA A:124 A:124 44.0 0.383 E -84.9 126.9 44.0 0.383 0.0
1f8a 1 Q13526 100.0 2e-120 X-RAY
 2000-08-23 ALA A:128 B:128 37.0 0.322 E -89.9 138.5 37.0 0.322 0.0 HOH
 2.675
 O
 O
2zr4 1 Q13526 99.39 2e-120 X-RAY
 2009-08-25 ALA A:124 A:124 40.0 0.348 E -90.8 149.3 40.0 0.348 0.0 HOH
 2.788
 O
 O
2zr5 1 Q13526 99.39 6e-120 X-RAY
 2009-08-25 ALA A:124 A:124 43.0 0.374 E -75.5 136.3 43.0 0.374 0.0 HOH
 2.566
 O
 O
2zqt 1 Q13526 99.39 7e-120 X-RAY
 2009-08-25 ALA A:124 A:124 43.0 0.374 E -86.9 150.0 43.0 0.374 0.0 HOH
 2.647
 O
 O
2zr6 1 Q13526 99.39 8e-120 X-RAY
 2009-08-25 ALA A:124 A:124 37.0 0.322 E -59.9 143.2 37.0 0.322 0.0 HOH
 3.650
 O
 O
3oob 1 Q13526 99.39 8e-120 X-RAY
 2011-08-17 ALA A:124 A:124 43.0 0.374 E -94.8 148.6 43.0 0.374 0.0 PE4
HOH
 9.661
2.726
 O
O
 O3
O
3wh0 1 Q13526 99.39 8e-120 X-RAY
 2014-10-15 ALA A:124 A:124 40.0 0.348 E -88.5 145.5 40.0 0.348 0.0 HOH
 2.494
 O
 O
5uy9 1 Q13526 99.39 8e-120 X-RAY
 2017-04-26 ALA A:124 A:124 54.0 0.47 E -98.0 143.7 45.0 0.391 0.079 B:None:0.078
 SO4
HOH
 8.845
4.138
 O
CB
 O2
O
2zqv 1 Q13526 99.39 1e-119 X-RAY
 2009-08-25 ALA A:124 A:124 40.0 0.348 E -81.5 147.2 40.0 0.348 0.0 HOH
 2.750
 O
 O
3tc5 1 Q13526 99.39 1e-119 X-RAY
 2011-08-31 ALA A:127 A:124 46.0 0.4 E -95.3 153.4 46.0 0.4 0.0 3T5
HOH
 5.591
2.711
 O
O
 C12
O
6o33 1 Q13526 98.77 1e-119 X-RAY
 2020-02-26 ALA A:124 A:124 44.0 0.383 E -88.8 150.0 37.0 0.322 0.061 B:None:0.061
 HOH
 2.683
 O
 O
2zqs 1 Q13526 99.39 2e-119 X-RAY
 2009-08-25 ALA A:124 A:124 40.0 0.348 E -88.6 148.1 40.0 0.348 0.0 HOH
 2.402
 O
 O
2itk 1 Q13526 99.39 2e-119 X-RAY
 2007-05-22 ALA A:128 A:124 39.0 0.339 E -87.6 146.3 28.0 0.243 0.096 B:None:0.096
 HOH
 4.007
 CB
 O
2q5a 1 Q13526 99.39 2e-119 X-RAY
 2007-06-26 ALA A:128 A:124 39.0 0.339 E -89.8 150.7 35.0 0.304 0.035 B:None:0.035
 HOH
 2.752
 O
 O
2xp3 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ALA A:128 A:124 47.0 0.409 E -90.5 145.7 47.0 0.409 0.0 HOH
 2.674
 O
 O
2xp4 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ALA A:128 A:124 44.0 0.383 E -90.1 147.5 44.0 0.383 0.0 HOH
 2.625
 O
 O
2xp5 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ALA A:128 A:124 47.0 0.409 E -86.4 145.7 47.0 0.409 0.0 HOH
 3.791
 CB
 O
2xp7 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ALA A:128 A:124 43.0 0.374 E -85.7 153.0 43.0 0.374 0.0 HOH
 3.019
 O
 O
2xp8 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ALA A:128 A:124 49.0 0.426 E -68.9 152.0 49.0 0.426 0.0 HOH
 3.011
 CB
 O
2xp9 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ALA A:128 A:124 44.0 0.383 E -90.9 147.6 44.0 0.383 0.0 HOH
 2.731
 O
 O
2xpa 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ALA A:128 A:124 37.0 0.322 E -91.4 145.1 37.0 0.322 0.0 HOH
 3.749
 CB
 O
2xpb 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ALA A:128 A:124 50.0 0.435 E -89.9 151.6 50.0 0.435 0.0 HOH
 2.792
 O
 O
3kab 1 Q13526 99.39 2e-119 X-RAY
 2009-12-22 ALA A:128 A:124 43.0 0.374 E -84.3 155.9 43.0 0.374 0.0 4BL
HOH
 9.997
3.919
 O
CB
 C12
O
3kag 1 Q13526 99.39 2e-119 X-RAY
 2009-12-22 ALA A:128 A:124 50.0 0.435 E -91.2 152.9 50.0 0.435 0.0 HOH
 2.575
 O
 O
3kah 1 Q13526 99.39 2e-119 X-RAY
 2009-12-22 ALA A:128 A:124 46.0 0.4 E -83.5 146.1 46.0 0.4 0.0 4DH
HOH
 8.933
3.659
 N
CB
 C29
O
3kai 1 Q13526 99.39 2e-119 X-RAY
 2009-12-22 ALA A:128 A:124 46.0 0.4 E -89.7 148.2 46.0 0.4 0.0 4FI
HOH
 9.040
3.469
 O
CB
 C24
O
3kce 1 Q13526 99.39 2e-119 X-RAY
 2009-12-22 ALA A:128 A:124 38.0 0.33 E -95.7 151.9 38.0 0.33 0.0 HOH
 3.283
 CB
 O
3ntp 1 Q13526 99.39 2e-119 X-RAY
 2012-01-04 ALA A:128 A:124 47.0 0.409 E -88.3 147.8 47.0 0.409 0.0 RZD
HOH
 4.627
2.978
 O
O
 C27
O
3odk 1 Q13526 99.39 2e-119 X-RAY
 2010-10-27 ALA A:128 A:124 54.0 0.47 E -59.9 158.6 54.0 0.47 0.0 HOH
 3.418
 CB
 O
6vaj 1 Q13526 98.77 2e-119 X-RAY
 2020-12-30 ALA A:139 A:124 42.0 0.365 E -84.0 145.2 42.0 0.365 0.0 QT7
HOH
 9.662
2.605
 O
O
 C3
O
4u84 1 Q13526 99.39 2e-119 X-RAY
 2015-04-08 ALA A:142 A:124 34.0 0.296 E -91.5 145.6 34.0 0.296 0.0 HOH
 2.582
 O
 O
4u85 1 Q13526 99.39 2e-119 X-RAY
 2015-04-08 ALA A:142 A:124 34.0 0.296 E -91.0 148.8 34.0 0.296 0.0 HOH
 4.502
 O
 O
4u86 1 Q13526 99.39 2e-119 X-RAY
 2015-04-08 ALA A:142 A:124 39.0 0.339 E -95.2 148.4 39.0 0.339 0.0 HOH
 2.694
 O
 O
2zqu 1 Q13526 99.39 3e-119 X-RAY
 2009-08-25 ALA A:124 A:124 46.0 0.4 E -98.8 155.1 46.0 0.4 0.0 HOH
 2.519
 O
 O
6o34 1 Q13526 98.16 7e-119 X-RAY
 2020-02-26 ALA A:124 A:124 40.0 0.348 E -88.0 147.2 35.0 0.304 0.044 B:None:0.043
 HOH
 2.071
 O
 O
2xp6 1 Q13526 98.77 9e-119 X-RAY
 2011-01-12 ALA A:128 A:124 47.0 0.409 E -89.4 152.9 47.0 0.409 0.0 HOH
 4.041
 CB
 O
3kad 1 Q13526 98.77 9e-119 X-RAY
 2009-12-22 ALA A:128 A:124 47.0 0.409 E -87.0 149.4 47.0 0.409 0.0 4C0
HOH
 8.605
3.676
 N
CB
 C21
O
3kaf 1 Q13526 98.77 9e-119 X-RAY
 2009-12-22 ALA A:128 A:124 47.0 0.409 E -82.9 152.5 47.0 0.409 0.0 4D9
HOH
 8.803
6.532
 O
N
 C26
O
2f21 1 Q13526 98.16 4e-117 X-RAY
 2006-06-20 ALA A:123 A:124 41.0 0.357 E -88.6 149.2 41.0 0.357 0.0 HOH
 2.697
 O
 O
1zcn 1 Q13526 98.16 6e-117 X-RAY
 2006-06-20 ALA A:122 A:124 46.0 0.4 E -90.9 148.0 46.0 0.4 0.0 1PE
HOH
 9.594
2.557
 O
O
 OH5
O
3tcz 1 Q13526 99.37 1e-115 X-RAY
 2012-06-20 ALA A:119 A:124 43.0 0.374 E -86.4 157.3 43.0 0.374 0.0 R2Z
HOH
 4.953
6.319
 O
N
 N5
O
3tdb 1 Q13526 99.37 1e-115 X-RAY
 2012-06-27 ALA A:119 A:124 33.0 0.287 E -81.8 152.7 33.0 0.287 0.0 3TB
HOH
 9.296
3.615
 O
CB
 O3
O
4qib 1 Q13526 99.36 4e-115 X-RAY
 2015-02-04 ALA A:120 A:124 45.0 0.391 E -93.5 148.5 45.0 0.391 0.0 HOH
 2.546
 O
 O
3kac 1 Q13526 97.54 8e-85 X-RAY
 2009-12-22 ALA A:84 A:124 35.0 0.304 E -82.5 147.9 35.0 0.304 0.0 HOH
 3.053
 O
 O
ALA B:84 B:124 38.0 0.33 E -90.0 145.1 NA NA NA
4tns 1 Q13526 98.35 1e-84 X-RAY
 2015-04-08 ALA A:112 A:124 40.0 0.348 E -89.8 147.7 40.0 0.348 0.0 REA
HOH
 9.928
3.068
 O
N
 C16
O
ALA B:112 B:124 27.0 0.235 E -89.6 150.8 NA NA NA
3i6c 1 Q13526 98.32 1e-83 X-RAY
 2010-04-21 ALA A:84 A:124 40.0 0.348 E -83.6 149.5 40.0 0.348 0.0 HOH
 2.921
 O
 O
ALA B:84 B:124 21.0 0.183 E -82.4 140.8 NA NA NA
3ik8 1 Q13526 98.32 1e-83 X-RAY
 2009-09-22 ALA A:84 A:124 42.0 0.365 E -89.8 146.2 42.0 0.365 0.0 HOH
 3.289
 O
 H1
ALA B:84 B:124 23.0 0.2 E -96.2 158.6 NA NA NA
3ikd 1 Q13526 98.32 1e-83 X-RAY
 2009-09-22 ALA A:84 A:124 43.0 0.374 E -83.3 150.4 43.0 0.374 0.0 J9Z
HOH
 6.164
3.369
 O
CB
 H12
H1
ALA B:84 B:124 26.0 0.226 E -88.6 154.1 NA NA NA
3ikg 1 Q13526 98.32 1e-83 X-RAY
 2009-09-22 ALA A:84 A:124 42.0 0.365 E -90.1 147.5 42.0 0.365 0.0 J8Z
HOH
 7.623
2.645
 N
O
 C19
O
ALA B:84 B:124 26.0 0.226 E -88.6 150.7 NA NA NA
3jyj 1 Q13526 98.32 1e-83 X-RAY
 2010-04-07 ALA A:84 A:124 41.0 0.357 E -87.9 143.1 41.0 0.357 0.0 JZI
HOH
 7.450
2.987
 O
O
 C16
O
ALA B:84 B:124 25.0 0.217 E -75.9 148.3 NA NA NA
4tyo 1 Q13526 98.32 1e-83 X-RAY
 2014-08-20 ALA A:84 A:124 42.0 0.365 E -87.1 144.8 42.0 0.365 0.0 39X
HOH
 6.510
3.067
 O
N
 H8
O
ALA B:84 B:124 32.0 0.278 E -76.8 141.4 NA NA NA
6dun 1 Q13526 98.31 5e-83 X-RAY
 2019-03-06 ALA A:83 A:124 28.0 0.243 E -82.8 144.7 28.0 0.243 0.0 HOH
 2.289
 H
 O
ALA B:83 B:124 42.0 0.365 E -89.0 146.4 NA NA NA
1nmw 1 Q13526 100.0 9e-81 NMR
 2003-07-15 ALA A:75 A:124 44.0 0.383 E -86.5 125.0 44.0 0.383 0.0
2ruc 1 Q13526 100.0 5e-80 NMR
 2014-12-17 ALA A:78 A:78 53.0 0.461 E -78.0 111.0 53.0 0.461 0.0
5gph 1 Q13526 99.12 1e-79 NMR
 2017-08-09 ALA A:78 A:78 62.0 0.539 E -81.8 119.9 62.0 0.539 0.0
2ruq 1 Q13526 99.12 1e-78 NMR
 2016-01-06 ALA A:78 A:78 56.0 0.487 E -86.1 108.4 56.0 0.487 0.0
2rur 1 Q13526 99.12 2e-78 NMR
 2016-01-06 ALA A:78 A:78 78.0 0.678 E -84.8 109.1 78.0 0.678 0.0
2rud 1 Q13526 99.12 4e-78 NMR
 2014-12-17 ALA A:78 A:78 33.0 0.287 E -84.4 110.0 33.0 0.287 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q13526-f1 1 Q13526 100.0 4e-121 ALA A:124 A:124 45.0 0.391 E -85.5 135.9