Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 9959808 . G A CCDS12220.1:NM_006221.3:c.425cGg>cAg_NP_006212.1:p.142R>Q Homo sapiens peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (PIN1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1pin 1 Q13526 100.0 9e-121 X-RAY
 1998-10-14 ARG A:142 A:142 90.0 0.4 -93.5 163.4 45.0 0.2 0.2 A:Q13526:0.2
 1PG
1PG
HOH
 9.090
8.451
3.810
 O
O
CA
 C3
C2
O
7sa5 1 Q13526 100.0 9e-121 NMR
 2021-10-20 ARG A:142 A:142 184.0 0.818 -97.0 161.8 184.0 0.818 0.0
1f8a 1 Q13526 100.0 2e-120 X-RAY
 2000-08-23 ARG A:146 B:146 87.0 0.387 -89.9 156.0 87.0 0.387 0.0 HOH
 2.385
 NH1
 O
2zr4 1 Q13526 99.39 2e-120 X-RAY
 2009-08-25 ARG A:142 A:142 89.0 0.396 -100.1 161.0 89.0 0.396 0.0 HOH
 3.368
 CA
 O
2zr5 1 Q13526 99.39 6e-120 X-RAY
 2009-08-25 ARG A:142 A:142 74.0 0.329 -110.5 159.1 74.0 0.329 0.0 HOH
 3.430
 CG
 O
2zqt 1 Q13526 99.39 7e-120 X-RAY
 2009-08-25 ARG A:142 A:142 86.0 0.382 -92.1 162.7 86.0 0.382 0.0 HOH
 3.006
 NH1
 O
2zr6 1 Q13526 99.39 8e-120 X-RAY
 2009-08-25 ARG A:142 A:142 79.0 0.351 -94.6 155.7 79.0 0.351 0.0 HOH
 4.075
 NH1
 O
3oob 1 Q13526 99.39 8e-120 X-RAY
 2011-08-17 ARG A:142 A:142 66.0 0.293 -89.0 158.7 66.0 0.293 0.0 PE4
HOH
 9.294
3.358
 NH2
NH2
 C2
O
3wh0 1 Q13526 99.39 8e-120 X-RAY
 2014-10-15 ARG A:142 A:142 167.0 0.742 -78.6 161.7 167.0 0.742 0.0 HOH
 2.713
 NH1
 O
5uy9 1 Q13526 99.39 8e-120 X-RAY
 2017-04-26 ARG A:142 A:142 69.0 0.307 -84.3 162.2 69.0 0.307 0.0 PE4
HOH
 9.276
3.225
 O
NH2
 C16
O
2zqv 1 Q13526 99.39 1e-119 X-RAY
 2009-08-25 ARG A:142 A:142 58.0 0.258 -114.5 152.3 58.0 0.258 0.0 HOH
 3.165
 CD
 O
3tc5 1 Q13526 99.39 1e-119 X-RAY
 2011-08-31 ARG A:145 A:142 87.0 NA -82.0 161.2 87.0 NA NA HOH
 3.129
 CD
 O
6o33 1 Q13526 98.77 1e-119 X-RAY
 2020-02-26 ARG A:142 A:142 90.0 0.4 -89.2 163.0 90.0 0.4 0.0 SO4
HOH
 3.821
2.790
 CG
NH1
 O2
O
2zqs 1 Q13526 99.39 2e-119 X-RAY
 2009-08-25 ARG A:142 A:142 85.0 0.378 -100.6 159.2 85.0 0.378 0.0 HOH
 3.508
 CA
 O
2itk 1 Q13526 99.39 2e-119 X-RAY
 2007-05-22 ARG A:146 A:142 60.0 0.267 -89.7 163.3 60.0 0.267 0.0 PE4
HOH
 8.322
2.703
 NH2
CZ
 C16
O
2q5a 1 Q13526 99.39 2e-119 X-RAY
 2007-06-26 ARG A:146 A:142 64.0 0.284 -83.6 161.2 64.0 0.284 0.0 16P
HOH
 6.390
2.678
 NH2
NH2
 C1
O
2xp3 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ARG A:146 A:142 72.0 0.32 -87.1 151.7 72.0 0.32 0.0 HOH
 3.762
 N
 O
2xp4 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ARG A:146 A:142 97.0 0.431 -81.8 158.9 97.0 0.431 0.0 12P
HOH
 8.442
3.056
 NH2
NH1
 C35
O
2xp5 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ARG A:146 A:142 70.0 0.311 -92.2 167.5 70.0 0.311 0.0 12P
HOH
 9.276
2.525
 NH2
NH2
 O34
O
2xp7 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ARG A:146 A:142 69.0 0.307 -87.3 166.4 69.0 0.307 0.0 12P
HOH
 8.357
2.758
 NH2
NH1
 C36
O
2xp8 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ARG A:146 A:142 106.0 0.471 -79.4 165.1 106.0 0.471 0.0 HOH
 4.138
 NE
 O
2xp9 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ARG A:146 A:142 100.0 0.444 -80.5 152.0 100.0 0.444 0.0 12P
HOH
 8.792
3.128
 NH2
NE
 C20
O
2xpa 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ARG A:146 A:142 79.0 0.351 -79.8 154.2 79.0 0.351 0.0 12P
HOH
 9.011
3.390
 NH1
NE
 C20
O
2xpb 1 Q13526 99.39 2e-119 X-RAY
 2011-01-12 ARG A:146 A:142 66.0 0.293 -93.4 162.4 66.0 0.293 0.0 HOH
 3.206
 CG
 O
3kab 1 Q13526 99.39 2e-119 X-RAY
 2009-12-22 ARG A:146 A:142 75.0 0.333 -95.4 164.2 75.0 0.333 0.0 12P
HOH
 8.140
3.578
 NH2
CG
 C32
O
3kag 1 Q13526 99.39 2e-119 X-RAY
 2009-12-22 ARG A:146 A:142 65.0 0.289 -81.8 155.3 65.0 0.289 0.0 12P
HOH
 6.646
3.594
 NH2
CD
 O37
O
3kah 1 Q13526 99.39 2e-119 X-RAY
 2009-12-22 ARG A:146 A:142 66.0 0.293 -91.6 162.1 66.0 0.293 0.0 12P
HOH
 9.399
3.392
 NH2
NH2
 C36
O
3kai 1 Q13526 99.39 2e-119 X-RAY
 2009-12-22 ARG A:146 A:142 71.0 0.316 -83.2 158.4 71.0 0.316 0.0 12P
HOH
 8.932
3.686
 NH2
CA
 O31
O
3kce 1 Q13526 99.39 2e-119 X-RAY
 2009-12-22 ARG A:146 A:142 68.0 0.302 -96.8 164.8 68.0 0.302 0.0 12P
HOH
 8.934
3.348
 NH2
CD
 C15
O
3ntp 1 Q13526 99.39 2e-119 X-RAY
 2012-01-04 ARG A:146 A:142 52.0 0.231 -93.6 161.4 52.0 0.231 0.0 PE8
HOH
 9.105
3.749
 NH1
CB
 C24
O
3odk 1 Q13526 99.39 2e-119 X-RAY
 2010-10-27 ARG A:146 A:142 66.0 0.293 -109.6 146.0 66.0 0.293 0.0 PE4
HOH
 8.888
3.532
 O
CG
 C3
O
6vaj 1 Q13526 98.77 2e-119 X-RAY
 2020-12-30 ARG A:157 A:142 89.0 0.396 -91.3 162.6 89.0 0.396 0.0 SO4
HOH
 3.706
2.941
 CA
NH1
 O1
O
4u84 1 Q13526 99.39 2e-119 X-RAY
 2015-04-08 ARG A:160 A:142 100.0 0.444 -80.3 163.3 100.0 0.444 0.0 15P
HOH
 8.372
2.877
 NH2
NH1
 O6
O
4u85 1 Q13526 99.39 2e-119 X-RAY
 2015-04-08 ARG A:160 A:142 54.0 0.24 -88.8 162.8 54.0 0.24 0.0 HOH
 2.908
 NE
 O
4u86 1 Q13526 99.39 2e-119 X-RAY
 2015-04-08 ARG A:160 A:142 104.0 0.462 -77.9 161.9 104.0 0.462 0.0 1PG
HOH
 8.490
3.133
 NH2
NH1
 C1
O
2zqu 1 Q13526 99.39 3e-119 X-RAY
 2009-08-25 ARG A:142 A:142 89.0 0.396 -102.7 156.0 89.0 0.396 0.0 HOH
 3.409
 CB
 O
6o34 1 Q13526 98.16 7e-119 X-RAY
 2020-02-26 ARG A:142 A:142 87.0 0.387 -89.2 161.7 87.0 0.387 0.0 2PE
GOL
HOH
 7.811
3.546
3.028
 NH2
CB
NH1
 C24
C3
O
2xp6 1 Q13526 98.77 9e-119 X-RAY
 2011-01-12 ARG A:146 A:142 65.0 0.289 -94.2 161.1 65.0 0.289 0.0 12P
HOH
 9.031
3.162
 NH2
NH1
 O34
O
3kad 1 Q13526 98.77 9e-119 X-RAY
 2009-12-22 ARG A:146 A:142 71.0 0.316 -95.5 159.3 71.0 0.316 0.0 12P
HOH
 9.074
3.385
 NH2
CD
 C36
O
3kaf 1 Q13526 98.77 9e-119 X-RAY
 2009-12-22 ARG A:146 A:142 86.0 0.382 -87.8 158.2 86.0 0.382 0.0 HOH
 3.672
 CA
 O
2f21 1 Q13526 98.16 4e-117 X-RAY
 2006-06-20 ARG A:141 A:142 89.0 0.396 -99.7 163.8 89.0 0.396 0.0 HOH
 2.906
 NH1
 O
1zcn 1 Q13526 98.16 6e-117 X-RAY
 2006-06-20 ARG A:140 A:142 88.0 0.391 -95.3 160.5 88.0 0.391 0.0 HOH
 2.952
 NH1
 O
3tcz 1 Q13526 99.37 1e-115 X-RAY
 2012-06-20 ARG A:137 A:142 70.0 0.311 -98.1 163.7 70.0 0.311 0.0 PE4
HOH
 9.176
3.252
 NH2
NH1
 C16
O
3tdb 1 Q13526 99.37 1e-115 X-RAY
 2012-06-27 ARG A:137 A:142 63.0 0.28 -91.4 161.2 63.0 0.28 0.0 PE4
HOH
 8.764
2.662
 NH2
NH1
 C16
O
4qib 1 Q13526 99.36 4e-115 X-RAY
 2015-02-04 ARG A:138 A:142 153.0 0.68 -81.6 160.7 153.0 0.68 0.0 PE4
SO4
HOH
 7.481
2.298
2.920
 H
HH21
HG3
 H161
O4
O
3kac 1 Q13526 97.54 8e-85 X-RAY
 2009-12-22 ARG A:102 A:142 196.0 0.871 -79.1 158.8 196.0 0.871 0.0 HOH
 2.415
 NH2
 O
ARG B:102 B:142 198.0 0.88 -80.7 160.7 NA NA NA
4tns 1 Q13526 98.35 1e-84 X-RAY
 2015-04-08 ARG A:130 A:142 185.0 0.822 -79.7 157.2 185.0 0.822 0.0 HOH
 3.599
 CA
 O
ARG B:130 B:142 200.0 0.889 -70.7 159.1 NA NA NA
3i6c 1 Q13526 98.32 1e-83 X-RAY
 2010-04-21 ARG A:102 A:142 104.0 NA -84.0 158.0 104.0 NA NA HOH
 3.562
 CA
 O
ARG B:102 B:142 197.0 0.876 -79.4 160.6 NA NA NA
3ik8 1 Q13526 98.32 1e-83 X-RAY
 2009-09-22 ARG A:102 A:142 186.0 0.827 -81.2 157.2 186.0 0.827 0.0 HOH
 1.551
 HH22
 H1
ARG B:102 B:142 188.0 0.836 -92.0 166.8 NA NA NA
3ikd 1 Q13526 98.32 1e-83 X-RAY
 2009-09-22 ARG A:102 A:142 184.0 0.818 -79.8 160.6 184.0 0.818 0.0 HOH
 2.155
 HH11
 O
ARG B:102 B:142 189.0 0.84 -77.7 159.3 NA NA NA
3ikg 1 Q13526 98.32 1e-83 X-RAY
 2009-09-22 ARG A:102 A:142 187.0 0.831 -79.6 155.2 187.0 0.831 0.0 HOH
 2.972
 NE
 O
ARG B:102 B:142 187.0 0.831 -79.1 159.7 NA NA NA
3jyj 1 Q13526 98.32 1e-83 X-RAY
 2010-04-07 ARG A:102 A:142 201.0 0.893 -88.0 157.7 201.0 0.893 0.0 HOH
 2.795
 CG
 O
ARG B:102 B:142 198.0 0.88 -79.7 159.0 NA NA NA
4tyo 1 Q13526 98.32 1e-83 X-RAY
 2014-08-20 ARG A:102 A:142 200.0 0.889 -86.5 159.7 200.0 0.889 0.0 HOH
 3.419
 CA
 O
ARG B:102 B:142 200.0 0.889 -82.3 160.7 NA NA NA
6dun 1 Q13526 98.31 5e-83 X-RAY
 2019-03-06 ARG A:101 A:142 187.0 0.831 -75.8 158.3 187.0 0.831 0.0 HOH
 2.107
 HH11
 O
ARG B:101 B:142 192.0 0.853 -80.4 157.1 NA NA NA
1nmw 1 Q13526 100.0 9e-81 NMR
 2003-07-15 ARG A:93 A:142 188.0 0.836 -87.5 177.2 188.0 0.836 0.0
2ruc 1 Q13526 100.0 5e-80 NMR
 2014-12-17 ARG A:96 A:96 169.0 0.751 -137.3 -175.7 169.0 0.751 0.0
5gph 1 Q13526 99.12 1e-79 NMR
 2017-08-09 ARG A:96 A:96 191.0 0.849 -90.5 168.7 191.0 0.849 0.0
2ruq 1 Q13526 99.12 1e-78 NMR
 2016-01-06 ARG A:96 A:96 176.0 0.782 -103.9 171.3 176.0 0.782 0.0
2rur 1 Q13526 99.12 2e-78 NMR
 2016-01-06 ARG A:96 A:96 166.0 0.738 -104.1 173.5 166.0 0.738 0.0
2rud 1 Q13526 99.12 4e-78 NMR
 2014-12-17 ARG A:96 A:96 172.0 0.764 -93.4 -178.8 172.0 0.764 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q13526-f1 1 Q13526 100.0 4e-121 ARG A:142 A:142 75.0 0.333 -79.1 159.7