Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 187490219 . A C CCDS2292.1:NM_002210.4:c.428cAt>cCt_NP_002201.1:p.143H>P Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6uja 1 P06756 99.9 0.0 EM
 2020-02-05 HIS A:113 A:113 49.0 0.251 E -114.4 154.0 16.0 0.082 0.169 B:P26012:0.169
6ujb 1 P06756 99.9 0.0 EM
 2020-02-05 HIS A:113 A:113 47.0 0.241 E -118.1 154.6 12.0 0.062 0.179 B:P26012:0.179
6ujc 1 P06756 99.9 0.0 EM
 2020-02-05 HIS A:113 A:113 41.0 0.21 E -115.7 156.0 10.0 0.051 0.159 B:P26012:0.159
3ije 1 P06756 99.9 0.0 X-RAY
 2009-09-29 HIS A:113 A:113 47.0 0.241 E -102.5 155.3 14.0 0.072 0.169 B:P05106:0.169
6msl 1 P06756 99.9 0.0 X-RAY
 2019-10-23 HIS A:113 A:113 42.0 0.215 E -102.3 159.8 13.0 0.067 0.148 B:P05106:0.149
6msu 1 P06756 99.9 0.0 X-RAY
 2019-10-23 HIS A:113 A:113 46.0 0.236 E -93.9 153.3 16.0 0.082 0.154 B:P05106:0.154
6djp 1 P06756 99.9 0.0 EM
 2018-07-25 HIS A:113 A:113 24.0 NA E -107.2 147.6 24.0 NA NA
4o02 1 P06756 99.9 0.0 X-RAY
 2014-04-02 HIS A:113 A:113 45.0 0.231 E -101.1 149.2 16.0 0.082 0.149 B:P05106:0.149
4g1e 1 P06756 99.9 0.0 X-RAY
 2012-12-12 HIS A:113 A:113 44.0 0.226 E -104.3 175.7 18.0 0.092 0.134 B:P05106:0.133
 SO4
HOH
 7.414
9.061
 CB
CE1
 O3
O
4g1m 1 P06756 99.9 0.0 X-RAY
 2012-12-12 HIS A:113 A:113 45.0 0.231 E -101.5 156.0 17.0 0.087 0.144 B:P05106:0.144
 HOH
 2.485
 ND1
 O
4mmx 1 P06756 99.9 0.0 X-RAY
 2014-03-26 HIS A:113 A:113 44.0 0.226 B -117.6 159.9 15.0 0.077 0.149 B:P05106:0.149
4mmy 1 P06756 99.9 0.0 X-RAY
 2014-03-26 HIS A:113 A:113 41.0 0.21 B -118.1 161.2 14.0 0.072 0.138 B:P05106:0.138
4mmz 1 P06756 99.9 0.0 X-RAY
 2014-03-26 HIS A:113 A:113 42.0 0.215 -112.6 152.6 9.0 0.046 0.169 B:P05106:0.169
6avq 1 P06756 100.0 0.0 EM
 2017-11-01 HIS A:113 A:113 25.0 NA E -116.5 148.6 25.0 NA NA
6avr 1 P06756 100.0 0.0 EM
 2017-11-01 HIS A:113 A:113 27.0 NA E -115.7 149.0 27.0 NA NA
6avu 1 P06756 100.0 0.0 EM
 2017-11-01 HIS A:113 A:113 26.0 NA E -117.2 147.7 26.0 NA NA
1jv2 1 14743192 99.9 0.0 X-RAY
 2001-10-17 HIS A:113 A:113 46.0 0.236 E -96.8 138.1 18.0 0.092 0.144 B:2443452:0.144
1l5g 1 14743192 99.9 0.0 X-RAY
 2002-04-17 HIS A:113 A:113 56.0 0.287 E -98.3 152.2 22.0 0.113 0.174 B:P05106:0.174
1m1x 1 14743192 99.9 0.0 X-RAY
 2002-08-14 HIS A:113 A:113 46.0 0.236 E -94.9 145.1 19.0 0.097 0.139 B:P05106:0.138
1u8c 1 P06756 99.9 0.0 X-RAY
 2004-12-28 HIS A:113 A:113 38.0 0.195 E -107.5 152.4 11.0 0.056 0.139 B:P05106:0.138
6mk0 1 P06756 99.9 0.0 X-RAY
 2019-09-25 HIS A:113 A:113 41.0 0.21 -109.3 155.8 13.0 0.067 0.143 B:P05106:0.144
6naj 1 P06756 99.9 0.0 X-RAY
 2019-12-11 HIS A:113 A:113 40.0 0.205 -105.7 163.7 8.0 0.041 0.164 B:P05106:0.164
4um8 1 P06756 99.66 0.0 X-RAY
 2014-11-12 HIS A:113 A:113 29.0 0.149 E -92.7 152.8 7.0 0.036 0.113 B:P18564:0.113
 CL
HOH
 7.965
6.845
 O
CD2
 CL
O
HIS C:113 C:113 27.0 0.138 E -92.8 152.1 NA NA NA
4um9 1 P06756 99.66 0.0 X-RAY
 2014-11-12 HIS A:113 A:113 28.0 0.144 E -108.6 152.5 NA NA NA
HIS C:113 C:113 27.0 0.138 E -109.3 151.1 6.0 0.031 0.107 D:P18564:0.108
 SO4
HOH
 7.148
7.002
 O
CD2
 O3
O
5ner 5 P06756 99.83 0.0 EM
 2017-06-21 HIS E:113 A:113 26.0 0.133 E -100.6 152.4 6.0 0.031 0.102 F:P18564:0.103
5net 5 P06756 99.83 0.0 EM
 2017-06-21 HIS E:113 A:113 24.0 0.123 E -100.6 152.4 5.0 0.026 0.097 F:P18564:0.097
5ffg 1 P06756 99.5 0.0 X-RAY
 2017-01-25 HIS A:113 A:113 49.0 0.251 E -107.3 152.0 22.0 0.113 0.138 B:P18564:0.138
 HOH
 4.451
 NE2
 O
5ffo 1 P06756 99.5 0.0 X-RAY
 2017-01-25 HIS A:113 A:113 34.0 0.174 E -104.6 150.0 10.0 0.051 0.123 B:P18564:0.123
HIS E:113 E:113 32.0 0.164 E -104.2 150.0 9.0 0.046 0.118 F:P18564:0.118
6om1 1 P06756 99.33 0.0 X-RAY
 2019-12-11 HIS A:113 A:113 47.0 0.241 E -119.8 152.1 14.0 0.072 0.169 B:P26012:0.169
 EDO
HOH
 9.723
2.618
 HE1
ND1
 O2
O
HIS C:113 C:113 53.0 0.272 E -115.0 151.8 NA NA NA
HIS E:113 E:113 53.0 0.272 E -119.1 148.4 NA NA NA
HIS G:113 G:113 51.0 0.262 E -104.3 148.2 NA NA NA
6om2 1 P06756 99.33 0.0 X-RAY
 2019-12-11 HIS A:113 A:113 47.0 0.241 E -108.4 157.0 15.0 0.077 0.164 B:P26012:0.164
 HOH
 7.097
 HD2
 O
HIS C:113 C:113 49.0 0.251 E -116.9 154.9 16.0 0.082 0.169 D:P26012:0.169
 MAN
HOH
 8.997
6.852
 HE1
HB2
 C6
O
5nem 5 P06756 99.16 0.0 EM
 2017-06-21 HIS E:111 A:113 25.0 0.128 E -100.6 152.4 6.0 0.031 0.097 F:P18564:0.097
5neu 5 P06756 99.16 0.0 EM
 2017-06-21 HIS E:111 A:113 28.0 0.144 E -85.5 152.5 9.0 0.046 0.098 F:P18564:0.097

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06756-f1 1 P06756 99.9 0.0 HIS A:143 A:143 44.0 0.226 E -102.1 146.3