Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr2 | 187514597 | . | G | A | CCDS2292.1:NM_002210.4:c.1382cGa>cAa_NP_002201.1:p.461R>Q | Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6uja | 1 | P06756 | 99.9 | 0.0 |
EM |
2020-02-05 | ARG | A:431 | A:431 | 76.0 | 0.338 | E | -133.2 | 161.4 | 76.0 | 0.338 | 0.0 | ||||||
| 6ujb | 1 | P06756 | 99.9 | 0.0 |
EM |
2020-02-05 | ARG | A:431 | A:431 | 79.0 | 0.351 | E | -132.9 | 162.0 | 79.0 | 0.351 | 0.0 | ||||||
| 6ujc | 1 | P06756 | 99.9 | 0.0 |
EM |
2020-02-05 | ARG | A:431 | A:431 | 82.0 | 0.364 | E | -132.8 | 160.1 | 82.0 | 0.364 | 0.0 | ||||||
| 3ije | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2009-09-29 | ARG | A:431 | A:431 | 73.0 | 0.324 | E | -132.5 | 156.8 | 73.0 | 0.324 | 0.0 | ||||||
| 6msl | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2019-10-23 | ARG | A:431 | A:431 | 51.0 | 0.227 | E | -135.7 | 161.3 | 51.0 | 0.227 | 0.0 | ||||||
| 6msu | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2019-10-23 | ARG | A:431 | A:431 | 75.0 | 0.333 | E | -140.4 | 162.7 | 75.0 | 0.333 | 0.0 | ||||||
| 6djp | 1 | P06756 | 99.9 | 0.0 |
EM |
2018-07-25 | ARG | A:431 | A:431 | 31.0 | NA | E | -134.0 | 162.7 | 31.0 | NA | NA | ||||||
| 4o02 | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2014-04-02 | ARG | A:431 | A:431 | 72.0 | 0.32 | E | -136.7 | 157.3 | 72.0 | 0.32 | 0.0 | ||||||
| 4g1e | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2012-12-12 | ARG | A:431 | A:431 | 73.0 | 0.324 | E | -136.5 | 163.2 | 73.0 | 0.324 | 0.0 |
HOH |
2.929 |
NH2 |
O |
||
| 4g1m | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2012-12-12 | ARG | A:431 | A:431 | 58.0 | 0.258 | E | -135.6 | 145.8 | 58.0 | 0.258 | 0.0 |
HOH |
5.556 |
O |
O |
||
| 4mmx | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2014-03-26 | ARG | A:431 | A:431 | 54.0 | 0.24 | E | -137.7 | 162.5 | 54.0 | 0.24 | 0.0 | ||||||
| 4mmy | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2014-03-26 | ARG | A:431 | A:431 | 72.0 | 0.32 | E | -147.7 | 160.0 | 72.0 | 0.32 | 0.0 | ||||||
| 4mmz | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2014-03-26 | ARG | A:431 | A:431 | 49.0 | 0.218 | E | -137.3 | 162.2 | 49.0 | 0.218 | 0.0 | ||||||
| 6avq | 1 | P06756 | 100.0 | 0.0 |
EM |
2017-11-01 | ARG | A:431 | A:431 | 25.0 | NA | E | -140.6 | 159.2 | 25.0 | NA | NA | ||||||
| 6avr | 1 | P06756 | 100.0 | 0.0 |
EM |
2017-11-01 | ARG | A:431 | A:431 | 24.0 | NA | E | -140.6 | 159.2 | 24.0 | NA | NA | ||||||
| 6avu | 1 | P06756 | 100.0 | 0.0 |
EM |
2017-11-01 | ARG | A:431 | A:431 | 23.0 | NA | E | -140.6 | 160.2 | 23.0 | NA | NA | ||||||
| 1jv2 | 1 | 14743192 | 99.9 | 0.0 |
X-RAY |
2001-10-17 | ARG | A:431 | A:431 | 47.0 | 0.209 | E | -162.7 | 159.1 | 47.0 | 0.209 | 0.0 | ||||||
| 1l5g | 1 | 14743192 | 99.9 | 0.0 |
X-RAY |
2002-04-17 | ARG | A:431 | A:431 | 40.0 | 0.178 | E | -147.2 | 166.1 | 40.0 | 0.178 | 0.0 | ||||||
| 1m1x | 1 | 14743192 | 99.9 | 0.0 |
X-RAY |
2002-08-14 | ARG | A:431 | A:431 | 34.0 | 0.151 | E | -158.4 | 159.9 | 34.0 | 0.151 | 0.0 | ||||||
| 1u8c | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2004-12-28 | ARG | A:431 | A:431 | 29.0 | 0.129 | E | 178.6 | 165.8 | 29.0 | 0.129 | 0.0 | ||||||
| 6mk0 | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2019-09-25 | ARG | A:431 | A:431 | 53.0 | 0.236 | E | -140.5 | 164.8 | 53.0 | 0.236 | 0.0 | ||||||
| 6naj | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2019-12-11 | ARG | A:431 | A:431 | 51.0 | 0.227 | E | -143.4 | 159.7 | 51.0 | 0.227 | 0.0 | ||||||
| 4um8 | 1 | P06756 | 99.66 | 0.0 |
X-RAY |
2014-11-12 | ARG | A:431 | A:431 | 52.0 | 0.231 | E | -131.0 | 160.7 | 52.0 | 0.231 | 0.0 |
HOH |
9.473 |
N |
O |
||
| ARG | C:431 | C:431 | 56.0 | 0.249 | E | -132.1 | 159.8 | NA | NA | NA | |||||||||||||
| 4um9 | 1 | P06756 | 99.66 | 0.0 |
X-RAY |
2014-11-12 | ARG | A:431 | A:431 | 45.0 | 0.2 | E | -143.0 | 150.0 | NA | NA | NA | ||||||
| ARG | C:431 | C:431 | 74.0 | 0.329 | E | -143.2 | 150.8 | 74.0 | 0.329 | 0.0 |
HOH |
2.414 |
NH2 |
O |
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| 5ner | 5 | P06756 | 99.83 | 0.0 |
EM |
2017-06-21 | ARG | E:431 | A:431 | 52.0 | 0.231 | E | -122.7 | 155.5 | 52.0 | 0.231 | 0.0 | ||||||
| 5net | 5 | P06756 | 99.83 | 0.0 |
EM |
2017-06-21 | ARG | E:431 | A:431 | 51.0 | 0.227 | E | -122.8 | 155.5 | 51.0 | 0.227 | 0.0 | ||||||
| 5ffg | 1 | P06756 | 99.5 | 0.0 |
X-RAY |
2017-01-25 | ARG | A:432 | A:432 | 60.0 | 0.267 | E | -145.3 | 151.0 | 60.0 | 0.267 | 0.0 |
HOH |
5.489 |
O |
O |
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| 5ffo | 1 | P06756 | 99.5 | 0.0 |
X-RAY |
2017-01-25 | ARG | A:432 | A:432 | 48.0 | 0.213 | E | -146.9 | 149.1 | 48.0 | 0.213 | 0.0 | ||||||
| ARG | E:432 | E:432 | 41.0 | 0.182 | E | -146.1 | 149.7 | 36.0 | 0.16 | 0.022 |
C:P01137:0.022 |
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| 6om1 | 1 | P06756 | 99.33 | 0.0 |
X-RAY |
2019-12-11 | ARG | A:432 | A:432 | 39.0 | 0.173 | E | -139.3 | 156.8 | 39.0 | 0.173 | 0.0 |
EDO HOH |
5.774 2.099 |
HH22 HH21 |
O2 O |
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| ARG | C:432 | C:432 | 62.0 | 0.276 | E | -144.7 | 164.6 | NA | NA | NA | |||||||||||||
| ARG | E:432 | E:432 | 39.0 | 0.173 | E | -152.1 | 164.1 | NA | NA | NA | |||||||||||||
| ARG | G:432 | G:432 | 43.0 | 0.191 | E | -151.8 | 162.1 | NA | NA | NA | |||||||||||||
| 6om2 | 1 | P06756 | 99.33 | 0.0 |
X-RAY |
2019-12-11 | ARG | A:432 | A:432 | 54.0 | 0.24 | E | -140.1 | 153.5 | 54.0 | 0.24 | 0.0 |
HOH |
7.190 |
HE |
O |
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| ARG | C:432 | C:432 | 58.0 | 0.258 | E | -139.4 | 157.0 | 58.0 | 0.258 | 0.0 |
HOH |
2.572 |
HH12 |
O |
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| 5nem | 5 | P06756 | 99.16 | 0.0 |
EM |
2017-06-21 | ARG | E:429 | A:431 | 50.0 | 0.222 | E | -122.8 | 155.5 | 50.0 | 0.222 | 0.0 | ||||||
| 5neu | 5 | P06756 | 99.16 | 0.0 |
EM |
2017-06-21 | ARG | E:429 | A:431 | 49.0 | 0.218 | E | -137.7 | 133.9 | 49.0 | 0.218 | 0.0 | ||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p06756-f1 | 1 | P06756 | 99.9 | 0.0 | ARG | A:461 | A:461 | 73.0 | 0.324 | E | -125.9 | 154.8 | |