Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr2 | 187516759 | . | T | A | CCDS2292.1:NM_002210.4:c.1448aTt>aAt_NP_002201.1:p.483I>N | Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6uja | 1 | P06756 | 99.9 | 0.0 |
EM |
2020-02-05 | ILE | A:453 | A:453 | 74.0 | NA | E | -113.5 | 123.7 | 74.0 | NA | NA | ||||||
| 6ujb | 1 | P06756 | 99.9 | 0.0 |
EM |
2020-02-05 | ILE | A:453 | A:453 | 70.0 | NA | E | -111.1 | 126.3 | 70.0 | NA | NA | ||||||
| 6ujc | 1 | P06756 | 99.9 | 0.0 |
EM |
2020-02-05 | ILE | A:453 | A:453 | 82.0 | NA | E | -96.9 | 111.1 | 82.0 | NA | NA | ||||||
| 3ije | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2009-09-29 | ILE | A:453 | A:453 | 54.0 | 0.309 | E | -89.6 | 125.3 | 54.0 | 0.309 | 0.0 |
NAG NAG |
7.135 7.806 |
O O |
O5 O6 |
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| 6msl | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2019-10-23 | ILE | A:453 | A:453 | 45.0 | 0.257 | E | -92.2 | 105.4 | 45.0 | 0.257 | 0.0 |
NAG NAG MN |
6.357 8.002 9.753 |
O O CD1 |
O7 O6 MN |
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| 6msu | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2019-10-23 | ILE | A:453 | A:453 | 41.0 | 0.234 | E | -99.1 | 109.3 | 41.0 | 0.234 | 0.0 |
NAG NAG |
6.735 9.445 |
O O |
O7 C1 |
||
| 6djp | 1 | P06756 | 99.9 | 0.0 |
EM |
2018-07-25 | ILE | A:453 | A:453 | 64.0 | NA | E | -122.8 | 125.8 | 64.0 | NA | NA | ||||||
| 4o02 | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2014-04-02 | ILE | A:453 | A:453 | 54.0 | NA | 173.1 | 163.2 | 54.0 | NA | NA | |||||||
| 4g1e | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2012-12-12 | ILE | A:453 | A:453 | 26.0 | 0.149 | E | -75.3 | 141.8 | 26.0 | 0.149 | 0.0 |
NAG NAG CA |
5.960 8.976 9.953 |
O O CD1 |
O7 C1 CA |
||
| 4g1m | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2012-12-12 | ILE | A:453 | A:453 | 50.0 | 0.286 | E | -104.0 | 112.6 | 50.0 | 0.286 | 0.0 |
NAG NAG HOH |
7.026 8.699 3.654 |
O O CG1 |
O7 O5 O |
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| 4mmx | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2014-03-26 | ILE | A:453 | A:453 | 37.0 | 0.211 | E | -110.4 | 102.0 | 37.0 | 0.211 | 0.0 |
NAG NAG MN |
7.370 9.356 9.811 |
O O CD1 |
O5 C1 MN |
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| 4mmy | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2014-03-26 | ILE | A:453 | A:453 | 36.0 | 0.206 | E | -98.4 | 113.9 | 36.0 | 0.206 | 0.0 |
NAG NAG |
7.252 9.029 |
O O |
O7 C1 |
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| 4mmz | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2014-03-26 | ILE | A:453 | A:453 | 42.0 | 0.24 | E | -117.4 | 134.2 | 42.0 | 0.24 | 0.0 |
NAG NAG MN |
6.477 7.153 9.804 |
O O CD1 |
C2 O6 MN |
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| 6avq | 1 | P06756 | 100.0 | 0.0 |
EM |
2017-11-01 | ILE | A:453 | A:453 | 69.0 | NA | E | -109.7 | 125.1 | 69.0 | NA | NA | ||||||
| 6avr | 1 | P06756 | 100.0 | 0.0 |
EM |
2017-11-01 | ILE | A:453 | A:453 | 67.0 | NA | E | -109.1 | 124.6 | 67.0 | NA | NA | ||||||
| 6avu | 1 | P06756 | 100.0 | 0.0 |
EM |
2017-11-01 | ILE | A:453 | A:453 | 78.0 | NA | E | -108.2 | 124.8 | 78.0 | NA | NA | ||||||
| 1jv2 | 1 | 14743192 | 99.9 | 0.0 |
X-RAY |
2001-10-17 | ILE | A:453 | A:453 | 43.0 | 0.246 | E | -99.6 | 128.1 | 43.0 | 0.246 | 0.0 |
NAG CA |
3.562 9.820 |
O CG2 |
O4 CA |
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| 1l5g | 1 | 14743192 | 99.9 | 0.0 |
X-RAY |
2002-04-17 | ILE | A:453 | A:453 | 49.0 | 0.28 | S | -102.4 | 90.9 | 49.0 | 0.28 | 0.0 |
NAG MN |
3.749 9.678 |
O CD1 |
O4 MN |
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| 1m1x | 1 | 14743192 | 99.9 | 0.0 |
X-RAY |
2002-08-14 | ILE | A:453 | A:453 | 42.0 | 0.24 | S | -102.1 | 92.8 | 42.0 | 0.24 | 0.0 |
NAG |
3.810 |
O |
O4 |
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| 1u8c | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2004-12-28 | ILE | A:453 | A:453 | 47.0 | 0.269 | S | -100.1 | 100.2 | 47.0 | 0.269 | 0.0 |
NAG |
5.615 |
O |
O5 |
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| 6mk0 | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2019-09-25 | ILE | A:453 | A:453 | 40.0 | 0.229 | E | -121.9 | 113.1 | 40.0 | 0.229 | 0.0 |
NAG NAG |
6.319 7.376 |
O O |
C8 O6 |
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| 6naj | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2019-12-11 | ILE | A:453 | A:453 | 39.0 | 0.223 | E | -117.1 | 130.6 | 39.0 | 0.223 | 0.0 |
NAG NAG MN |
7.016 7.379 9.908 |
O O CD1 |
C2 O6 MN |
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| 4um8 | 1 | P06756 | 99.66 | 0.0 |
X-RAY |
2014-11-12 | ILE | A:453 | A:453 | 121.0 | 0.691 | E | -92.3 | 92.0 | 121.0 | 0.691 | 0.0 |
NAG NAG NI |
5.195 9.623 6.448 |
O O CG2 |
O7 C1 NI |
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| ILE | C:453 | C:453 | 124.0 | 0.709 | E | -93.4 | 91.9 | NA | NA | NA | |||||||||||||
| 4um9 | 1 | P06756 | 99.66 | 0.0 |
X-RAY |
2014-11-12 | ILE | A:453 | A:453 | 116.0 | 0.663 | E | -96.7 | 123.2 | NA | NA | NA | ||||||
| ILE | C:453 | C:453 | 120.0 | 0.686 | E | -97.7 | 123.3 | 120.0 | 0.686 | 0.0 |
NAG NAG HOH |
5.152 9.018 7.884 |
O O CG2 |
O7 C1 O |
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| 5ner | 5 | P06756 | 99.83 | 0.0 |
EM |
2017-06-21 | ILE | E:453 | A:453 | 123.0 | 0.703 | E | -105.1 | 100.7 | 123.0 | 0.703 | 0.0 |
NAG NAG MAN |
4.206 8.938 8.458 |
O O N |
O7 C1 O6 |
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| 5net | 5 | P06756 | 99.83 | 0.0 |
EM |
2017-06-21 | ILE | E:453 | A:453 | 124.0 | 0.709 | E | -105.2 | 100.8 | 124.0 | 0.709 | 0.0 |
NAG NAG MAN |
4.205 8.938 8.458 |
O O N |
O7 C1 O6 |
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| 5ffg | 1 | P06756 | 99.5 | 0.0 |
X-RAY |
2017-01-25 | ILE | A:454 | A:454 | 105.0 | 0.6 | E | -105.9 | 125.5 | 105.0 | 0.6 | 0.0 |
NAG NAG HOH |
5.474 8.166 3.330 |
O O N |
C8 O6 O |
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| 5ffo | 1 | P06756 | 99.5 | 0.0 |
X-RAY |
2017-01-25 | ILE | A:454 | A:454 | 105.0 | 0.6 | B | -107.7 | 113.0 | 105.0 | 0.6 | 0.0 |
NAG NAG |
3.709 8.254 |
O CG1 |
C8 O6 |
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| ILE | E:454 | E:454 | 142.0 | 0.811 | S | -107.9 | 113.5 | 142.0 | 0.811 | 0.0 |
NAG NAG |
3.666 8.691 |
O CG1 |
C8 O6 |
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| 6om1 | 1 | P06756 | 99.33 | 0.0 |
X-RAY |
2019-12-11 | ILE | A:454 | A:454 | 85.0 | 0.486 | E | -91.0 | 116.0 | 85.0 | 0.486 | 0.0 |
NAG NAG BMA |
7.171 9.284 9.883 |
O O H |
C2 C1 O2 |
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| ILE | C:454 | C:454 | 91.0 | 0.52 | E | -93.4 | 119.0 | NA | NA | NA | |||||||||||||
| ILE | E:454 | E:454 | 92.0 | 0.526 | B | -104.3 | 108.8 | NA | NA | NA | |||||||||||||
| ILE | G:454 | G:454 | 107.0 | 0.611 | E | -76.6 | 116.7 | NA | NA | NA | |||||||||||||
| 6om2 | 1 | P06756 | 99.33 | 0.0 |
X-RAY |
2019-12-11 | ILE | A:454 | A:454 | 97.0 | 0.554 | E | -91.9 | 103.1 | 97.0 | 0.554 | 0.0 |
NAG NAG MAN HOH |
5.533 6.523 9.228 4.323 |
O H H O |
O7 O6 O6 O |
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| ILE | C:454 | C:454 | 95.0 | 0.543 | E | -116.7 | 111.6 | 95.0 | 0.543 | 0.0 |
NAG NAG GLY HOH |
5.377 7.824 9.352 3.414 |
O H HG21 O |
O7 O6 CA O |
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| 5nem | 5 | P06756 | 99.16 | 0.0 |
EM |
2017-06-21 | ILE | E:451 | A:453 | 124.0 | 0.709 | E | -105.1 | 100.7 | 124.0 | 0.709 | 0.0 |
NAG NAG MAN |
4.206 8.937 8.458 |
O O N |
O7 C1 O6 |
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| 5neu | 5 | P06756 | 99.16 | 0.0 |
EM |
2017-06-21 | ILE | E:451 | A:453 | 96.0 | 0.549 | S | -73.8 | 144.8 | 96.0 | 0.549 | 0.0 | ||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p06756-f1 | 1 | P06756 | 99.9 | 0.0 | ILE | A:483 | A:483 | 46.0 | 0.263 | E | -102.5 | 120.3 | |