Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr2 | 187516774 | . | A | C | CCDS2292.1:NM_002210.4:c.1463aAt>aCt_NP_002201.1:p.488N>T | Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6uja | 1 | P06756 | 99.9 | 0.0 |
EM |
2020-02-05 | ASN | A:458 | A:458 | 46.0 | NA | -86.6 | 72.0 | 46.0 | NA | NA | |||||||
| 6ujb | 1 | P06756 | 99.9 | 0.0 |
EM |
2020-02-05 | ASN | A:458 | A:458 | 54.0 | NA | -89.2 | 72.4 | 54.0 | NA | NA | |||||||
| 6ujc | 1 | P06756 | 99.9 | 0.0 |
EM |
2020-02-05 | ASN | A:458 | A:458 | 71.0 | NA | -83.8 | 73.7 | 71.0 | NA | NA | |||||||
| 3ije | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2009-09-29 | ASN | A:458 | A:458 | 94.0 | 0.588 | -69.4 | 92.8 | 94.0 | 0.588 | 0.0 |
NAG NAG |
1.457 6.729 |
ND2 ND2 |
C1 C1 |
|||
| 6msl | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2019-10-23 | ASN | A:458 | A:458 | 80.0 | 0.5 | -89.2 | 104.2 | 80.0 | 0.5 | 0.0 |
NAG NAG |
1.436 6.602 |
ND2 ND2 |
C1 C1 |
|||
| 6msu | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2019-10-23 | ASN | A:458 | A:458 | 93.0 | 0.581 | -103.5 | 103.3 | 93.0 | 0.581 | 0.0 |
NAG NAG |
1.435 6.547 |
ND2 ND2 |
C1 C1 |
|||
| 6djp | 1 | P06756 | 99.9 | 0.0 |
EM |
2018-07-25 | ASN | A:458 | A:458 | 51.0 | NA | -82.1 | 64.3 | 51.0 | NA | NA | |||||||
| 4o02 | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2014-04-02 | ASN | A:458 | A:458 | 59.0 | NA | G | -85.9 | 10.2 | 59.0 | NA | NA | ||||||
| 4g1e | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2012-12-12 | ASN | A:458 | A:458 | 72.0 | 0.45 | -58.7 | -63.0 | 72.0 | 0.45 | 0.0 |
NAG NAG |
1.440 6.501 |
ND2 ND2 |
C1 C1 |
|||
| 4g1m | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2012-12-12 | ASN | A:458 | A:458 | 85.0 | 0.531 | -101.8 | 66.1 | 85.0 | 0.531 | 0.0 |
NAG NAG |
1.442 6.649 |
ND2 ND2 |
C1 C1 |
|||
| 4mmx | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2014-03-26 | ASN | A:458 | A:458 | 77.0 | 0.481 | -99.6 | 103.9 | 77.0 | 0.481 | 0.0 |
NAG NAG |
1.438 6.513 |
ND2 ND2 |
C1 C1 |
|||
| 4mmy | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2014-03-26 | ASN | A:458 | A:458 | 76.0 | 0.475 | -101.5 | 102.9 | 76.0 | 0.475 | 0.0 |
NAG NAG |
1.436 6.549 |
ND2 ND2 |
C1 C1 |
|||
| 4mmz | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2014-03-26 | ASN | A:458 | A:458 | 98.0 | 0.613 | -90.9 | 12.0 | 98.0 | 0.613 | 0.0 |
NAG NAG |
1.431 6.447 |
ND2 ND2 |
C1 C1 |
|||
| 6avq | 1 | P06756 | 100.0 | 0.0 |
EM |
2017-11-01 | ASN | A:458 | A:458 | 64.0 | NA | -84.2 | 69.3 | 64.0 | NA | NA | |||||||
| 6avr | 1 | P06756 | 100.0 | 0.0 |
EM |
2017-11-01 | ASN | A:458 | A:458 | 61.0 | NA | -83.2 | 67.0 | 61.0 | NA | NA | |||||||
| 6avu | 1 | P06756 | 100.0 | 0.0 |
EM |
2017-11-01 | ASN | A:458 | A:458 | 60.0 | NA | -82.7 | 64.1 | 60.0 | NA | NA | |||||||
| 1jv2 | 1 | 14743192 | 99.9 | 0.0 |
X-RAY |
2001-10-17 | ASN | A:458 | A:458 | 52.0 | 0.325 | -115.3 | 126.1 | 52.0 | 0.325 | 0.0 |
NAG |
1.428 |
ND2 |
C1 |
|||
| 1l5g | 1 | 14743192 | 99.9 | 0.0 |
X-RAY |
2002-04-17 | ASN | A:458 | A:458 | 74.0 | 0.463 | -100.3 | 114.8 | 74.0 | 0.463 | 0.0 |
NAG |
1.447 |
ND2 |
C1 |
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| 1m1x | 1 | 14743192 | 99.9 | 0.0 |
X-RAY |
2002-08-14 | ASN | A:458 | A:458 | 58.0 | 0.362 | -106.6 | 132.7 | 58.0 | 0.362 | 0.0 |
NAG |
1.454 |
ND2 |
C1 |
|||
| 1u8c | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2004-12-28 | ASN | A:458 | A:458 | 97.0 | 0.606 | -28.2 | 108.3 | 97.0 | 0.606 | 0.0 |
NAG |
1.450 |
ND2 |
C1 |
|||
| 6mk0 | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2019-09-25 | ASN | A:458 | A:458 | 98.0 | 0.613 | -118.3 | 46.7 | 98.0 | 0.613 | 0.0 |
NAG NAG |
1.415 6.701 |
ND2 ND2 |
C1 C1 |
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| 6naj | 1 | P06756 | 99.9 | 0.0 |
X-RAY |
2019-12-11 | ASN | A:458 | A:458 | 99.0 | 0.619 | -99.1 | 39.4 | 99.0 | 0.619 | 0.0 |
NAG NAG |
1.433 6.497 |
ND2 ND2 |
C1 C1 |
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| 4um8 | 1 | P06756 | 99.66 | 0.0 |
X-RAY |
2014-11-12 | ASN | A:458 | A:458 | 69.0 | 0.431 | -70.2 | -60.5 | 69.0 | 0.431 | 0.0 |
NAG NAG |
1.434 6.538 |
ND2 ND2 |
C1 C1 |
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| ASN | C:458 | C:458 | 76.0 | 0.475 | -71.5 | -59.4 | NA | NA | NA | ||||||||||||||
| 4um9 | 1 | P06756 | 99.66 | 0.0 |
X-RAY |
2014-11-12 | ASN | A:458 | A:458 | 72.0 | 0.45 | -52.7 | -59.3 | NA | NA | NA | |||||||
| ASN | C:458 | C:458 | 83.0 | 0.519 | T | -75.7 | -52.5 | 83.0 | 0.519 | 0.0 |
NAG NAG HOH |
1.443 6.663 3.391 |
ND2 ND2 CA |
C1 C1 O |
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| 5ner | 5 | P06756 | 99.83 | 0.0 |
EM |
2017-06-21 | ASN | E:458 | A:458 | 81.0 | 0.506 | -68.8 | -58.1 | 81.0 | 0.506 | 0.0 |
NAG NAG |
1.289 6.260 |
ND2 ND2 |
C1 C1 |
|||
| 5net | 5 | P06756 | 99.83 | 0.0 |
EM |
2017-06-21 | ASN | E:458 | A:458 | 80.0 | 0.5 | -68.9 | -58.1 | 80.0 | 0.5 | 0.0 |
NAG NAG |
1.289 6.260 |
ND2 ND2 |
C1 C1 |
|||
| 5ffg | 1 | P06756 | 99.5 | 0.0 |
X-RAY |
2017-01-25 | ASN | A:459 | A:459 | 78.0 | 0.487 | -91.2 | 88.9 | 78.0 | 0.487 | 0.0 |
NAG NAG HOH |
1.436 6.575 3.301 |
ND2 ND2 ND2 |
C1 C1 O |
|||
| 5ffo | 1 | P06756 | 99.5 | 0.0 |
X-RAY |
2017-01-25 | ASN | A:459 | A:459 | 68.0 | 0.425 | -131.5 | 87.5 | 68.0 | 0.425 | 0.0 |
NAG NAG |
1.441 6.554 |
ND2 ND2 |
C1 C1 |
|||
| ASN | E:459 | E:459 | 69.0 | 0.431 | -131.8 | 86.6 | 69.0 | 0.431 | 0.0 |
NAG NAG |
1.441 6.604 |
ND2 ND2 |
C1 C1 |
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| 6om1 | 1 | P06756 | 99.33 | 0.0 |
X-RAY |
2019-12-11 | ASN | A:459 | A:459 | 77.0 | 0.481 | T | -70.3 | -57.5 | 77.0 | 0.481 | 0.0 |
NAG NAG HOH |
1.438 6.572 8.103 |
ND2 ND2 N |
C1 C1 O |
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| ASN | C:459 | C:459 | 70.0 | 0.438 | T | -61.5 | -46.7 | NA | NA | NA | |||||||||||||
| ASN | E:459 | E:459 | 73.0 | 0.456 | T | -60.3 | -54.3 | NA | NA | NA | |||||||||||||
| ASN | G:459 | G:459 | 75.0 | 0.469 | T | -59.8 | -70.0 | NA | NA | NA | |||||||||||||
| 6om2 | 1 | P06756 | 99.33 | 0.0 |
X-RAY |
2019-12-11 | ASN | A:459 | A:459 | 75.0 | 0.469 | -98.0 | 80.4 | 75.0 | 0.469 | 0.0 |
NAG NAG HOH |
1.444 6.618 3.213 |
ND2 ND2 ND2 |
C1 C1 O |
|||
| ASN | C:459 | C:459 | 76.0 | 0.475 | -97.5 | 76.2 | 76.0 | 0.475 | 0.0 |
NAG NAG HOH |
1.444 6.604 3.232 |
ND2 ND2 ND2 |
C1 C1 O |
||||||||||
| 5nem | 5 | P06756 | 99.16 | 0.0 |
EM |
2017-06-21 | ASN | E:456 | A:458 | 82.0 | 0.512 | -68.9 | -58.1 | 82.0 | 0.512 | 0.0 |
NAG NAG |
1.288 6.259 |
ND2 ND2 |
C1 C1 |
|||
| 5neu | 5 | P06756 | 99.16 | 0.0 |
EM |
2017-06-21 | ASN | E:456 | A:458 | 69.0 | 0.431 | -75.3 | -54.4 | 69.0 | 0.431 | 0.0 | |||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p06756-f1 | 1 | P06756 | 99.9 | 0.0 | ASN | A:488 | A:488 | 95.0 | 0.594 | -80.5 | 65.6 | ||