Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 187523779 . T A CCDS2292.1:NM_002210.4:c.1734ttT>ttA_NP_002201.1:p.578F>L Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6uja 1 P06756 99.9 0.0 EM
 2020-02-05 PHE A:548 A:548 73.0 NA -156.4 162.8 73.0 NA NA
6ujb 1 P06756 99.9 0.0 EM
 2020-02-05 PHE A:548 A:548 64.0 NA -161.6 161.7 64.0 NA NA
6ujc 1 P06756 99.9 0.0 EM
 2020-02-05 PHE A:548 A:548 71.0 NA -160.0 164.7 71.0 NA NA
3ije 1 P06756 99.9 0.0 X-RAY
 2009-09-29 PHE A:548 A:548 15.0 0.071 -54.0 125.8 13.0 0.062 0.009 B:P05106:0.01
6msl 1 P06756 99.9 0.0 X-RAY
 2019-10-23 PHE A:548 A:548 27.0 0.129 S -95.8 -82.0 8.0 0.038 0.091 B:P05106:0.09
6msu 1 P06756 99.9 0.0 X-RAY
 2019-10-23 PHE A:548 A:548 19.0 0.09 -156.1 170.1 15.0 0.071 0.019 B:P05106:0.019
6djp 1 P06756 99.9 0.0 EM
 2018-07-25 PHE A:548 A:548 20.0 NA -88.8 66.3 20.0 NA NA
4o02 1 P06756 99.9 0.0 X-RAY
 2014-04-02 PHE A:548 A:548 42.0 NA -94.0 128.3 42.0 NA NA
4g1e 1 P06756 99.9 0.0 X-RAY
 2012-12-12 PHE A:548 A:548 22.0 0.105 -174.3 163.5 22.0 0.105 0.0 HOH
 8.455
 CE2
 O
4g1m 1 P06756 99.9 0.0 X-RAY
 2012-12-12 PHE A:548 A:548 19.0 0.09 -141.5 171.6 18.0 0.086 0.004 B:P05106:0.005
4mmx 1 P06756 99.9 0.0 X-RAY
 2014-03-26 PHE A:548 A:548 25.0 0.119 S -159.8 -178.6 25.0 0.119 0.0
4mmy 1 P06756 99.9 0.0 X-RAY
 2014-03-26 PHE A:548 A:548 14.0 0.067 -136.5 -176.5 11.0 0.052 0.015 B:P05106:0.014
4mmz 1 P06756 99.9 0.0 X-RAY
 2014-03-26 PHE A:548 A:548 27.0 0.129 S -121.5 -58.4 6.0 0.029 0.1 B:P05106:0.1
 NA
 4.980
 N
 NA
6avq 1 P06756 100.0 0.0 EM
 2017-11-01 PHE A:548 A:548 35.0 NA -107.1 120.1 35.0 NA NA
6avr 1 P06756 100.0 0.0 EM
 2017-11-01 PHE A:548 A:548 35.0 NA -107.6 121.2 35.0 NA NA
6avu 1 P06756 100.0 0.0 EM
 2017-11-01 PHE A:548 A:548 36.0 NA -98.9 108.3 36.0 NA NA
1jv2 1 14743192 99.9 0.0 X-RAY
 2001-10-17 PHE A:548 A:548 14.0 0.067 -174.5 136.5 14.0 0.067 0.0
1l5g 1 14743192 99.9 0.0 X-RAY
 2002-04-17 PHE A:548 A:548 16.0 0.076 -167.9 164.4 16.0 0.076 0.0
1m1x 1 14743192 99.9 0.0 X-RAY
 2002-08-14 PHE A:548 A:548 14.0 0.067 -161.8 165.8 14.0 0.067 0.0
1u8c 1 P06756 99.9 0.0 X-RAY
 2004-12-28 PHE A:548 A:548 13.0 0.062 -152.6 153.1 13.0 0.062 0.0
6mk0 1 P06756 99.9 0.0 X-RAY
 2019-09-25 PHE A:548 A:548 18.0 0.086 S -131.2 -28.1 11.0 0.052 0.034 B:P05106:0.033
6naj 1 P06756 99.9 0.0 X-RAY
 2019-12-11 PHE A:548 A:548 17.0 0.081 S -122.7 -20.0 14.0 0.067 0.014 B:P05106:0.014
4um8 1 P06756 99.66 0.0 X-RAY
 2014-11-12 PHE A:548 A:548 14.0 0.067 -159.1 153.3 14.0 0.067 0.0 HOH
 4.224
 CB
 O
PHE C:548 C:548 17.0 0.081 -158.4 158.2 NA NA NA
4um9 1 P06756 99.66 0.0 X-RAY
 2014-11-12 PHE A:548 A:548 11.0 0.052 -153.9 148.0 NA NA NA
PHE C:548 C:548 16.0 0.076 -150.7 153.6 16.0 0.076 0.0 HOH
 3.964
 CB
 O
5ner 5 P06756 99.83 0.0 EM
 2017-06-21 PHE E:548 A:548 17.0 0.081 -160.6 152.0 17.0 0.081 0.0
5net 5 P06756 99.83 0.0 EM
 2017-06-21 PHE E:548 A:548 17.0 0.081 -160.7 152.0 17.0 0.081 0.0
5ffg 1 P06756 99.5 0.0 X-RAY
 2017-01-25 PHE A:549 A:549 14.0 0.067 -152.1 158.7 14.0 0.067 0.0 MES
HOH
 3.239
2.539
 CA
O
 O3S
O
5ffo 1 P06756 99.5 0.0 X-RAY
 2017-01-25 PHE A:549 A:549 9.0 0.043 -159.9 125.3 9.0 0.043 0.0
PHE E:549 E:549 13.0 0.062 -159.5 125.7 13.0 0.062 0.0
6om1 1 P06756 99.33 0.0 X-RAY
 2019-12-11 PHE A:549 A:549 10.0 0.048 -159.6 143.6 10.0 0.048 0.0
PHE C:549 C:549 10.0 0.048 -162.3 139.5 NA NA NA
PHE E:549 E:549 3.0 0.014 -154.5 137.4 NA NA NA
PHE G:549 G:549 3.0 0.014 -153.9 139.5 NA NA NA
6om2 1 P06756 99.33 0.0 X-RAY
 2019-12-11 PHE A:549 A:549 12.0 0.057 -152.7 153.7 12.0 0.057 0.0 HOH
 8.723
 HB3
 O
PHE C:549 C:549 12.0 0.057 -162.0 154.6 12.0 0.057 0.0 HOH
 3.191
 HB2
 O
5nem 5 P06756 99.16 0.0 EM
 2017-06-21 PHE E:544 A:548 16.0 0.076 -160.7 152.0 16.0 0.076 0.0
5neu 5 P06756 99.16 0.0 EM
 2017-06-21 PHE E:544 A:548 35.0 0.167 -84.4 -175.4 35.0 0.167 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06756-f1 1 P06756 99.9 0.0 PHE A:578 A:578 8.0 0.038 -136.6 142.2