Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 204735407 . C A CCDS2362.1:NM_005214.4:c.208Cgg>Agg_NP_005205.2:p.70R>R Homo sapiens cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3osk 1 P16410 98.44 1e-90 X-RAY
 2010-12-08 ARG A:35 A:35 85.0 0.378 E -111.4 123.0 85.0 0.378 0.0 HOH
 3.061
 NH2
 O
ARG B:35 B:35 96.0 0.427 E -111.5 122.5 96.0 0.427 0.0 HOH
 2.522
 O
 O
5xj3 3 P16410 100.0 1e-90 X-RAY
 2018-04-25 ARG C:36 C:70 71.0 0.316 E -75.0 132.5 NA NA NA
ARG F:36 F:70 75.0 0.333 E -80.9 130.8 NA NA NA
ARG I:36 I:70 73.0 0.324 E -82.5 129.3 NA NA NA
ARG L:36 L:70 75.0 0.333 E -75.7 123.1 NA NA NA
1i85 2 P16410 100.0 2e-90 X-RAY
 2001-04-04 ARG C:35 C:35 75.0 0.333 E -136.0 104.7 75.0 0.333 0.0
ARG D:35 D:35 70.0 0.311 E -140.3 104.3 30.0 0.133 0.178 B:P42081:0.178
5ggv 3 P16410 100.0 2e-90 X-RAY
 2016-11-09 ARG C:35 Y:35 83.0 0.369 E -103.7 126.7 68.0 0.302 0.067 B:None:0.067
 HOH
 2.865
 NH2
 O
7elx 3 P16410 100.0 2e-90 X-RAY
 2021-06-30 ARG E:35 c:35 78.0 0.347 E -111.2 124.6 NA NA NA
ARG F:35 C:35 77.0 0.342 E -113.2 123.9 39.0 0.173 0.169 A:None:0.169
 HOH
 3.598
 NH2
 O
1i8l 2 P16410 99.21 9e-90 X-RAY
 2001-04-04 ARG C:35 C:35 82.0 0.364 E -116.5 127.7 14.0 0.062 0.302 A:P33681:0.302
ARG D:35 D:35 83.0 0.369 E -124.8 109.6 NA NA NA
2x44 1 P16410 97.66 1e-89 X-RAY
 2010-04-07 ARG A:36 D:35 75.0 0.333 E -122.9 118.3 75.0 0.333 0.0 HOH
 3.056
 O
 O
1ah1 1 P16410 100.0 1e-89 NMR
 1998-04-15 ARG A:34 A:33 88.0 0.391 E -60.0 124.6 88.0 0.391 0.0
6rqm 2 P16410 100.0 1e-89 X-RAY
 2020-07-08 ARG B:34 A:35 71.0 0.316 E -123.7 118.5 54.0 0.24 0.076 A:None:0.076
3bx7 1 P16410 100.0 5e-89 X-RAY
 2009-01-20 ARG A:33 C:35 80.0 0.356 E -123.9 127.0 31.0 0.138 0.218 B:None:0.218
 HOH
 2.904
 O
 O
6xy2 1 P16410 100.0 6e-88 X-RAY
 2020-12-09 ARG A:33 A:35 58.0 0.258 E -107.7 121.2 58.0 0.258 0.0
6rpj 1 P16410 100.0 2e-85 X-RAY
 2020-07-08 ARG A:34 A:35 75.0 0.333 E -112.2 109.5 NA NA NA
ARG C:34 C:35 78.0 0.347 E -114.1 108.9 NA NA NA
ARG E:34 E:35 67.0 0.298 E -109.4 110.9 NA NA NA
ARG G:34 G:35 66.0 0.293 E -110.3 108.7 3.0 0.013 0.28 A:P16410:0.28
 NA
 5.943
 CD
 NA
7dv4 1 P16410 100.0 1e-83 X-RAY
 2022-01-12 ARG A:35 A:35 91.0 0.404 E -122.0 127.2 1.0 0.004 0.4 B:None:0.4
 EDO
HOH
 9.141
6.157
 NH2
N
 O1
O
ARG C:35 C:35 92.0 0.409 E -118.4 128.1 NA NA NA
ARG E:35 E:35 95.0 0.422 E -121.3 129.9 NA NA NA
ARG G:35 G:35 100.0 0.444 E -112.3 127.8 3.0 0.013 0.431 H:None:0.431
 HOH
 2.654
 O
 O
5tru 3 P16410 100.0 2e-83 X-RAY
 2017-05-10 ARG E:34 c:35 99.0 0.44 E -114.2 109.5 NA NA NA
ARG F:34 C:35 87.0 0.387 E -119.9 109.4 40.0 0.178 0.209 B:None:0.209
6rp8 3 P16410 100.0 2e-83 X-RAY
 2020-07-08 ARG E:34 C:35 85.0 0.378 E -107.2 128.3 NA NA NA
ARG F:34 c:35 78.0 0.347 E -112.1 130.8 24.0 0.107 0.24 A:None:0.24
4kkn 1 Q28090 80.65 3e-70 X-RAY
 2013-06-12 ARG A:40 A:68 83.0 0.369 E -102.5 121.6 83.0 0.369 0.0 HOH
 2.800
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p16410-f1 1 P16410 100.0 2e-168 ARG A:70 A:70 82.0 0.364 E -110.9 127.8