Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 204735420 . T A CCDS2362.1:NM_005214.4:c.221cTt>cAt_NP_005205.2:p.74L>H Homo sapiens cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3osk 1 P16410 98.44 1e-90 X-RAY
 2010-12-08 LEU A:39 A:39 30.0 0.176 E -115.6 126.3 30.0 0.176 0.0 HOH
 3.881
 CD1
 O
LEU B:39 B:39 17.0 0.1 E -113.4 141.9 17.0 0.1 0.0 HOH
 3.369
 CD2
 O
5xj3 3 P16410 100.0 1e-90 X-RAY
 2018-04-25 LEU C:40 C:74 27.0 0.159 E -118.4 142.9 NA NA NA
LEU F:40 F:74 28.0 0.165 E -120.6 139.3 NA NA NA
LEU I:40 I:74 30.0 0.176 E -116.8 143.6 NA NA NA
LEU L:40 L:74 28.0 0.165 E -118.0 143.7 NA NA NA
1i85 2 P16410 100.0 2e-90 X-RAY
 2001-04-04 LEU C:39 C:39 31.0 0.182 -99.7 -165.1 31.0 0.182 0.0
LEU D:39 D:39 33.0 0.194 -95.6 -165.1 33.0 0.194 0.0
5ggv 3 P16410 100.0 2e-90 X-RAY
 2016-11-09 LEU C:39 Y:39 30.0 0.176 E -110.5 148.0 9.0 0.053 0.123 B:None:0.124
 HOH
 3.611
 CD2
 O
7elx 3 P16410 100.0 2e-90 X-RAY
 2021-06-30 LEU E:39 c:39 30.0 0.176 E -111.9 147.8 NA NA NA
LEU F:39 C:39 30.0 0.176 E -111.9 151.3 1.0 0.006 0.17 A:None:0.171
 HOH
 4.631
 CD2
 O
1i8l 2 P16410 99.21 9e-90 X-RAY
 2001-04-04 LEU C:39 C:39 23.0 0.135 E -105.2 142.6 23.0 0.135 0.0
LEU D:39 D:39 29.0 0.171 E -100.9 165.7 NA NA NA
2x44 1 P16410 97.66 1e-89 X-RAY
 2010-04-07 LEU A:40 D:39 39.0 0.229 E -114.1 147.6 39.0 0.229 0.0 HOH
 6.354
 C
 O
1ah1 1 P16410 100.0 1e-89 NMR
 1998-04-15 LEU A:38 A:37 23.0 0.135 E -120.1 153.4 23.0 0.135 0.0 NAG
NAG
 4.829
8.628
 HD11
HD12
 H82
HO6
6rqm 2 P16410 100.0 1e-89 X-RAY
 2020-07-08 LEU B:38 A:39 34.0 0.2 E -108.9 167.6 1.0 0.006 0.194 A:None:0.194
3bx7 1 P16410 100.0 5e-89 X-RAY
 2009-01-20 LEU A:37 C:39 29.0 0.171 E -112.2 136.2 19.0 0.112 0.059 B:None:0.059
 HOH
 6.338
 C
 O
6xy2 1 P16410 100.0 6e-88 X-RAY
 2020-12-09 LEU A:37 A:39 30.0 0.176 E -118.5 144.2 30.0 0.176 0.0
6rpj 1 P16410 100.0 2e-85 X-RAY
 2020-07-08 LEU A:38 A:39 22.0 0.129 E -103.4 118.0 NA NA NA
LEU C:38 C:39 21.0 0.124 E -103.0 121.3 NA NA NA
LEU E:38 E:39 23.0 0.135 E -105.0 119.9 NA NA NA
LEU G:38 G:39 22.0 0.129 E -105.7 118.5 22.0 0.129 0.0 NA
 8.038
 CD2
 NA
7dv4 1 P16410 100.0 1e-83 X-RAY
 2022-01-12 LEU A:39 A:39 18.0 0.106 E -111.4 138.9 6.0 0.035 0.071 H:None:0.071
LEU C:39 C:39 27.0 0.159 E -103.1 136.4 NA NA NA
LEU E:39 E:39 11.0 0.065 E -111.5 125.4 NA NA NA
LEU G:39 G:39 19.0 0.112 E -105.1 132.5 4.0 0.024 0.088 A:P16410:0.088
 HOH
 7.296
 CD2
 O
5tru 3 P16410 100.0 2e-83 X-RAY
 2017-05-10 LEU E:38 c:39 36.0 0.212 E -110.6 155.2 NA NA NA
LEU F:38 C:39 26.0 0.153 E -113.8 158.2 7.0 0.041 0.112 B:None:0.112
6rp8 3 P16410 100.0 2e-83 X-RAY
 2020-07-08 LEU E:38 C:39 35.0 0.206 E -103.3 151.2 NA NA NA
LEU F:38 c:39 33.0 0.194 E -104.6 152.5 1.0 0.006 0.188 A:None:0.188
4kkn 1 Q28090 80.65 3e-70 X-RAY
 2013-06-12 LEU A:44 A:72 23.0 0.135 E -115.5 128.4 23.0 0.135 0.0 HOH
 3.898
 CD2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p16410-f1 1 P16410 100.0 2e-168 LEU A:74 A:74 30.0 0.176 E -109.2 131.5