Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 204735600 . T A CCDS2362.1:NM_005214.4:c.401aTg>aAg_NP_005205.2:p.134M>K Homo sapiens cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3osk 1 P16410 98.44 1e-90 X-RAY
 2010-12-08 MET A:99 A:99 48.0 0.259 E -77.7 -47.5 48.0 0.259 0.0 GOL
HOH
 9.557
2.632
 N
O
 O2
O
MET B:99 B:99 44.0 0.238 E -99.2 -14.5 44.0 0.238 0.0 HOH
 3.293
 O
 O
5xj3 3 P16410 100.0 1e-90 X-RAY
 2018-04-25 MET C:100 C:134 64.0 0.346 -90.4 -80.7 NA NA NA
MET F:100 F:134 62.0 0.335 -81.5 -90.4 NA NA NA
MET I:100 I:134 64.0 0.346 -91.1 -85.0 NA NA NA
MET L:100 L:134 63.0 0.341 -85.9 -74.9 NA NA NA
1i85 2 P16410 100.0 2e-90 X-RAY
 2001-04-04 MET C:99 C:99 68.0 0.368 -67.7 -153.7 68.0 0.368 0.0
MET D:99 D:99 67.0 0.362 -64.1 -158.4 1.0 0.005 0.357 B:P42081:0.357
5ggv 3 P16410 100.0 2e-90 X-RAY
 2016-11-09 MET C:99 Y:99 72.0 0.389 E -98.6 -30.7 3.0 0.016 0.373 B:None:0.373
 HOH
 3.423
 SD
 O
7elx 3 P16410 100.0 2e-90 X-RAY
 2021-06-30 MET E:99 c:99 83.0 0.449 E -90.7 -31.2 NA NA NA
MET F:99 C:99 74.0 0.4 E -90.4 -30.7 3.0 0.016 0.384 A:None:0.384
 HOH
 3.790
 CG
 O
1i8l 2 P16410 99.21 9e-90 X-RAY
 2001-04-04 MET C:99 C:99 68.0 0.368 E -78.0 -39.6 0.0 0.0 0.368 A:P33681:0.368
MET D:99 D:99 66.0 0.357 E -75.1 -45.1 NA NA NA
2x44 1 P16410 97.66 1e-89 X-RAY
 2010-04-07 MET A:100 D:99 56.0 0.303 E -125.7 135.0 35.0 0.189 0.114 A:P16410:0.114
 HOH
 3.264
 CB
 O
1ah1 1 P16410 100.0 1e-89 NMR
 1998-04-15 MET A:98 A:99 68.0 0.368 -78.4 -38.3 68.0 0.368 0.0
6rqm 2 P16410 100.0 1e-89 X-RAY
 2020-07-08 MET B:98 A:99 54.0 0.292 E -79.5 -54.7 31.0 0.168 0.124 A:None:0.124
3bx7 1 P16410 100.0 5e-89 X-RAY
 2009-01-20 MET A:97 C:99 65.0 0.351 E -79.6 -32.0 28.0 0.151 0.2 B:None:0.2
 HOH
 3.047
 O
 O
6xy2 1 P16410 100.0 6e-88 X-RAY
 2020-12-09 MET A:97 A:99 69.0 0.373 E -90.6 -61.2 69.0 0.373 0.0
6rpj 1 P16410 100.0 2e-85 X-RAY
 2020-07-08 MET A:98 A:99 63.0 0.341 E -82.4 -36.4 NA NA NA
MET C:98 C:99 66.0 0.357 E -84.2 -32.2 NA NA NA
MET E:98 E:99 62.0 0.335 E -77.6 -33.1 NA NA NA
MET G:98 G:99 63.0 0.341 E -80.8 -39.4 5.0 0.027 0.314 A:P16410:0.314
 NA
 9.217
 CE
 NA
7dv4 1 P16410 100.0 1e-83 X-RAY
 2022-01-12 MET A:99 A:99 67.0 0.362 E -94.2 -35.8 2.0 0.011 0.351 B:None:0.351
 EDO
HOH
 9.420
3.659
 O
CE
 C1
O
MET C:99 C:99 67.0 0.362 E -94.5 -33.2 NA NA NA
MET E:99 E:99 68.0 0.368 E -87.2 -47.7 NA NA NA
MET G:99 G:99 64.0 0.346 E -85.3 -53.2 3.0 0.016 0.33 H:None:0.33
 HOH
 6.836
 SD
 O
5tru 3 P16410 100.0 2e-83 X-RAY
 2017-05-10 MET E:98 c:99 87.0 0.47 E -86.0 -43.6 NA NA NA
MET F:98 C:99 85.0 0.459 E -103.9 -28.2 2.0 0.011 0.448 B:None:0.449
6rp8 3 P16410 100.0 2e-83 X-RAY
 2020-07-08 MET E:98 C:99 84.0 0.454 E -81.7 -40.1 NA NA NA
MET F:98 c:99 86.0 0.465 E -80.8 -44.7 9.0 0.049 0.416 A:None:0.416
 HOH
 9.930
 SD
 O
4kkn 1 Q28090 80.65 3e-70 X-RAY
 2013-06-12 MET A:104 A:132 83.0 0.449 E -96.0 -20.5 83.0 0.449 0.0 HOH
 2.862
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p16410-f1 1 P16410 100.0 2e-168 MET A:134 A:134 71.0 0.384 E -92.8 -36.9