Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 204735656 . G A CCDS2362.1:NM_005214.4:c.457Gat>Aat_NP_005205.2:p.153D>N Homo sapiens cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant 1, mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3osk 1 P16410 98.44 1e-90 X-RAY
 2010-12-08 ASP A:118 A:118 80.0 0.533 -86.5 114.6 73.0 0.487 0.046 B:P16410:0.047
 HOH
 2.672
 OD2
 O
ASP B:118 B:118 50.0 0.333 -85.6 131.6 49.0 0.327 0.006 A:P16410:0.007
 HOH
 2.589
 O
 O
5xj3 3 P16410 100.0 1e-90 X-RAY
 2018-04-25 ASP C:119 C:153 113.0 0.753 -114.2 156.2 NA NA NA
ASP F:119 F:153 111.0 0.74 -114.9 153.3 NA NA NA
ASP I:119 I:153 107.0 0.713 -122.4 151.9 NA NA NA
ASP L:119 L:153 113.0 0.753 -116.4 153.2 NA NA NA
1i85 2 P16410 100.0 2e-90 X-RAY
 2001-04-04 ASP C:118 C:118 86.0 0.573 179.8 81.9 19.0 0.127 0.446 D:P16410:0.447
ASP D:118 D:118 89.0 0.593 171.5 86.3 18.0 0.12 0.473 C:P16410:0.473
5ggv 3 P16410 100.0 2e-90 X-RAY
 2016-11-09 ASP C:118 Y:118 95.0 0.633 -81.8 118.0 95.0 0.633 0.0 HOH
 2.828
 N
 O
7elx 3 P16410 100.0 2e-90 X-RAY
 2021-06-30 ASP E:118 NA:NA DO NA DO DO DO NA NA NA
ASP F:118 NA:NA DO NA DO DO DO NA NA NA
1i8l 2 P16410 99.21 9e-90 X-RAY
 2001-04-04 ASP C:118 C:118 85.0 0.567 -71.4 110.0 85.0 0.567 0.0
ASP D:118 D:118 81.0 0.54 -93.4 116.0 NA NA NA
2x44 1 P16410 97.66 1e-89 X-RAY
 2010-04-07 ASP A:119 D:118 151.0 1.0 -87.6 109.0 130.0 0.867 0.133 A:P16410:0.14
 HOH
 2.992
 OD2
 O
1ah1 1 P16410 100.0 1e-89 NMR
 1998-04-15 ASP A:117 A:119 97.0 0.647 -100.5 108.0 97.0 0.647 0.0
6rqm 2 P16410 100.0 1e-89 X-RAY
 2020-07-08 ASP B:117 A:118 107.0 0.713 -137.0 95.8 107.0 0.713 0.0
3bx7 1 P16410 100.0 5e-89 X-RAY
 2009-01-20 ASP A:116 C:118 83.0 0.553 -73.0 133.3 83.0 0.553 0.0 HOH
 2.565
 OD1
 O
6xy2 1 P16410 100.0 6e-88 X-RAY
 2020-12-09 ASP A:116 A:118 81.0 0.54 -94.2 137.4 81.0 0.54 0.0
6rpj 1 P16410 100.0 2e-85 X-RAY
 2020-07-08 ASP A:117 A:118 84.0 0.56 -84.0 125.9 NA NA NA
ASP C:117 C:118 83.0 0.553 -86.0 126.0 NA NA NA
ASP E:117 E:118 77.0 0.513 -85.8 124.8 NA NA NA
ASP G:117 G:118 81.0 0.54 -88.3 122.3 81.0 0.54 0.0
7dv4 1 P16410 100.0 1e-83 X-RAY
 2022-01-12 ASP A:118 A:118 162.0 NA 49.0 360.0 162.0 NA NA HOH
 2.632
 O
 O
ASP C:118 C:118 148.0 NA -129.6 360.0 NA NA NA
ASP E:118 E:118 168.0 NA 88.5 360.0 NA NA NA
ASP G:118 G:118 178.0 NA 64.4 360.0 178.0 NA NA HOH
 7.058
 OXT
 O
5tru 3 P16410 100.0 2e-83 X-RAY
 2017-05-10 ASP E:117 c:118 99.0 NA -111.9 360.0 NA NA NA
ASP F:117 NA:NA DO NA DO DO DO NA NA NA
6rp8 3 P16410 100.0 2e-83 X-RAY
 2020-07-08 ASP E:117 C:118 121.0 0.807 49.0 360.0 NA NA NA
ASP F:117 NA:NA DO NA DO DO DO NA NA NA
4kkn 1 Q28090 80.65 3e-70 X-RAY
 2013-06-12 ASP A:123 A:151 150.0 1.0 -81.1 360.0 150.0 1.0 0.0 HOH
 2.645
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p16410-f1 1 P16410 100.0 2e-168 ASP A:153 A:153 100.0 0.667 -62.3 124.5