Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 219922192 . G A CCDS33380.1:NM_002181.3:c.540taC>taT_NP_002172.2:p.180Y>Y Homo sapiens indian hedgehog (IHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k7g 1 Q14623 100.0 2e-127 X-RAY
 2011-01-26 TYR A:165 B:180 21.0 0.091 E -79.3 78.3 21.0 0.091 0.0 ZN
HOH
 9.153
2.492
 C
OH
 ZN
O
3k7i 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 TYR A:165 B:180 21.0 0.091 E -79.1 76.4 21.0 0.091 0.0 ZN
HOH
 9.174
2.580
 C
OH
 ZN
O
3k7h 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 TYR A:165 B:180 20.0 0.087 E -78.2 76.3 20.0 0.087 0.0 ZN
HOH
 9.205
2.629
 C
OH
 ZN
O
3k7j 1 Q14623 99.43 7e-127 X-RAY
 2011-01-26 TYR A:165 B:180 18.0 0.078 E -74.5 67.1 18.0 0.078 0.0 ZN
SO4
HOH
 9.251
9.891
2.650
 C
N
OH
 ZN
O4
O
3n1f 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 TYR A:156 A:180 22.0 0.096 E -76.7 76.6 22.0 0.096 0.0 ZN
HOH
 9.303
2.656
 C
OH
 ZN
O
TYR B:156 B:180 26.0 0.113 E -79.2 75.2 NA NA NA
3n1m 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 TYR A:156 B:180 27.0 0.117 E -80.7 83.4 27.0 0.117 0.0 ZN
HOH
 9.215
2.481
 HA
HH
 ZN
O
3n1o 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 TYR A:156 A:180 21.0 0.091 E -72.2 70.3 21.0 0.091 0.0 ZN
HOH
 9.115
2.500
 C
OH
 ZN
O
TYR B:156 B:180 23.0 0.1 -76.2 67.1 NA NA NA
TYR C:156 C:180 25.0 0.109 -69.3 74.2 NA NA NA
3n1p 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 TYR A:156 B:180 20.0 0.087 -63.5 78.5 20.0 0.087 0.0 ZN
 8.660
 C
 ZN
6dmy 2 Q15465 88.57 1e-113 EM
 2018-07-11 TYR B:155 B:175 24.0 0.104 -71.2 83.0 24.0 0.104 0.0 ZN
 9.357
 C
 ZN
6n7g 2 Q15465 88.57 2e-113 EM
 2019-05-29 TYR C:152 C:175 21.0 0.091 -78.9 85.7 21.0 0.091 0.0 ZN
 9.203
 C
 ZN
TYR F:152 F:175 20.0 0.087 -78.9 85.8 20.0 0.087 0.0 ZN
 9.203
 C
 ZN
6n7h 2 Q15465 88.57 2e-113 EM
 2019-05-29 TYR C:152 C:175 21.0 0.091 -78.9 85.8 21.0 0.091 0.0 ZN
 9.203
 C
 ZN
6n7k 2 Q15465 88.57 2e-113 EM
 2019-05-29 TYR C:152 C:175 21.0 0.091 -78.9 85.7 21.0 0.091 0.0 ZN
 9.203
 C
 ZN
TYR F:152 F:175 20.0 0.087 -78.9 85.8 20.0 0.087 0.0 ZN
 9.203
 C
 ZN
6rvd 2 Q15465 88.57 2e-113 EM
 2019-10-02 TYR C:152 C:175 19.0 0.083 -70.7 86.3 19.0 0.083 0.0 ZN
 8.345
 C
 ZN
6e1h 2 Q15465 88.57 2e-113 EM
 2018-08-29 TYR B:153 C:175 19.0 0.083 -71.5 80.2 19.0 0.083 0.0 ZN
 8.708
 C
 ZN
6oev 2 Q15465 88.57 2e-113 EM
 2019-04-17 TYR B:153 C:175 25.0 0.109 -66.3 93.4 25.0 0.109 0.0 ZN
 7.331
 C
 ZN
3m1n 1 Q15465 88.51 3e-112 X-RAY
 2010-03-16 TYR A:153 A:175 30.0 0.13 E -78.8 74.5 30.0 0.13 0.0 ZN
HOH
 9.164
2.581
 C
OH
 ZN
O
TYR B:153 B:175 20.0 0.087 E -83.8 73.8 NA NA NA
3ho5 2 Q15465 89.76 2e-110 X-RAY
 2009-06-23 TYR C:147 H:175 25.0 0.109 -75.8 79.5 NA NA NA
3mxw 1 Q15465 89.76 2e-110 X-RAY
 2010-05-26 TYR A:147 A:175 30.0 0.13 E -86.5 78.2 30.0 0.13 0.0 ZN
SO4
HOH
 9.299
9.171
2.625
 C
C
OH
 ZN
O2
O
6pjv 1 Q15465 89.76 2e-110 X-RAY
 2019-11-13 TYR A:147 A:175 29.0 0.126 E -81.9 79.5 29.0 0.126 0.0 DMS
DMS
GOL
ZN
MG
HOH
 8.118
7.915
9.220
8.635
8.623
1.888
 N
H
HE2
C
C
HH
 H22
O
H12
ZN
MG
O
6rmg 2 Q15465 89.76 8e-110 EM
 2019-10-09 TYR B:263 B:175 26.0 0.113 -77.7 71.4 26.0 0.113 0.0 ZN
 9.333
 C
 ZN
1vhh 1 Q62226 90.74 3e-108 X-RAY
 1996-01-29 TYR A:143 A:176 26.0 0.113 E -74.4 74.3 26.0 0.113 0.0 ZN
HOH
 9.054
1.935
 C
HH
 ZN
O
3d1m 1 Q62226 89.22 8e-108 X-RAY
 2008-09-23 TYR A:155 A:176 27.0 0.117 E -80.0 75.2 27.0 0.117 0.0 ZN
HOH
 8.750
2.584
 C
OH
 ZN
O
TYR B:155 B:176 27.0 0.117 E -84.1 73.5 NA NA NA
7rpk 2 Q62226 89.7 3e-107 EM
 2021-10-27 TYR B:151 H:176 23.0 0.1 E -76.1 81.2 23.0 0.1 0.0 ZN
 9.313
 C
 ZN
4c4m 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 TYR A:139 A:176 22.0 0.096 E -78.7 79.4 22.0 0.096 0.0 ZN
HOH
 9.305
2.616
 C
OH
 ZN
O
4c4n 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 TYR A:139 A:176 28.0 0.122 E -78.4 76.7 28.0 0.122 0.0 SGN
ZN
HOH
 7.838
9.135
5.710
 OH
C
OH
 O5S
ZN
O
TYR B:139 B:176 29.0 0.126 E -77.3 76.5 29.0 0.126 0.0 ZN
HOH
 9.208
7.116
 C
O
 ZN
O
3n1r 1 Q62226 91.67 6e-105 X-RAY
 2010-06-02 TYR A:141 A:176 26.0 0.113 E -75.4 66.7 26.0 0.113 0.0 ZN
HOH
 9.109
3.229
 C
OH
 ZN
O
2wg4 1 Q62226 91.61 1e-104 X-RAY
 2009-06-30 TYR A:137 A:176 25.0 0.109 -68.9 74.2 5.0 0.022 0.087 B:Q96QV1:0.087
 ZN
 9.439
 C
 ZN
2wfx 1 Q62226 92.11 3e-103 X-RAY
 2009-06-30 TYR A:137 A:176 25.0 0.109 E -74.0 65.7 1.0 0.004 0.105 B:Q96QV1:0.104
 ZN
 9.273
 C
 ZN

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14623-f1 1 Q14623 100.0 0.0 TYR A:180 A:180 24.0 0.104 -76.5 72.9