Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 219922200 . C A CCDS33380.1:NM_002181.3:c.532Gtg>Ttg_NP_002172.2:p.178V>L Homo sapiens indian hedgehog (IHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k7g 1 Q14623 100.0 2e-127 X-RAY
 2011-01-26 VAL A:163 B:178 0.0 0.0 E -137.3 131.8 0.0 0.0 0.0 ZN
SO4
HOH
 9.341
7.661
3.842
 C
O
CG2
 ZN
O1
O
3k7i 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 VAL A:163 B:178 0.0 0.0 E -136.9 129.2 0.0 0.0 0.0 ZN
SO4
HOH
 9.347
7.691
3.851
 C
O
CG2
 ZN
O1
O
3k7h 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 VAL A:163 B:178 0.0 0.0 E -134.8 133.8 0.0 0.0 0.0 ZN
HOH
 9.386
3.782
 C
CG2
 ZN
O
3k7j 1 Q14623 99.43 7e-127 X-RAY
 2011-01-26 VAL A:163 B:178 0.0 0.0 E -133.7 126.0 0.0 0.0 0.0 ZN
SO4
HOH
 9.370
7.442
4.015
 C
O
N
 ZN
O4
O
3n1f 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 VAL A:154 A:178 0.0 0.0 E -133.0 132.3 0.0 0.0 0.0 ZN
HOH
 8.544
3.209
 HA
HG23
 ZN
O
VAL B:154 B:178 0.0 0.0 E -135.3 133.4 NA NA NA
3n1m 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 VAL A:154 B:178 0.0 0.0 E -136.1 133.2 0.0 0.0 0.0 ZN
HOH
 8.546
3.095
 HA
HG23
 ZN
O
3n1o 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 VAL A:154 A:178 0.0 0.0 E -130.4 130.9 0.0 0.0 0.0 ZN
HOH
 9.462
3.993
 C
N
 ZN
O
VAL B:154 B:178 0.0 0.0 E -125.7 136.3 NA NA NA
VAL C:154 C:178 0.0 0.0 E -122.5 129.7 NA NA NA
3n1p 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 VAL A:154 B:178 0.0 0.0 E -127.9 134.0 0.0 0.0 0.0 ZN
 9.761
 C
 ZN
6dmy 2 Q15465 88.57 1e-113 EM
 2018-07-11 VAL B:153 B:173 0.0 0.0 E -125.1 105.5 0.0 0.0 0.0
6n7g 2 Q15465 88.57 2e-113 EM
 2019-05-29 VAL C:150 C:173 1.0 0.006 E -93.0 125.7 1.0 0.006 0.0 ZN
 9.663
 C
 ZN
VAL F:150 F:173 1.0 0.006 E -93.1 125.6 1.0 0.006 0.0 ZN
 9.663
 C
 ZN
6n7h 2 Q15465 88.57 2e-113 EM
 2019-05-29 VAL C:150 C:173 1.0 0.006 E -93.0 125.6 1.0 0.006 0.0 ZN
 9.663
 C
 ZN
6n7k 2 Q15465 88.57 2e-113 EM
 2019-05-29 VAL C:150 C:173 1.0 0.006 E -93.0 125.7 1.0 0.006 0.0 ZN
 9.663
 C
 ZN
VAL F:150 F:173 1.0 0.006 E -93.1 125.6 1.0 0.006 0.0 ZN
 9.663
 C
 ZN
6rvd 2 Q15465 88.57 2e-113 EM
 2019-10-02 VAL C:150 C:173 0.0 0.0 E -112.7 129.1 0.0 0.0 0.0 ZN
 9.314
 C
 ZN
6e1h 2 Q15465 88.57 2e-113 EM
 2018-08-29 VAL B:151 C:173 0.0 0.0 E -90.7 162.9 0.0 0.0 0.0 ZN
 9.710
 C
 ZN
6oev 2 Q15465 88.57 2e-113 EM
 2019-04-17 VAL B:151 C:173 1.0 0.006 E -77.6 158.6 1.0 0.006 0.0 ZN
 8.237
 C
 ZN
3m1n 1 Q15465 88.51 3e-112 X-RAY
 2010-03-16 VAL A:151 A:173 0.0 0.0 E -135.9 127.9 0.0 0.0 0.0 ZN
SO4
HOH
 9.338
8.693
7.118
 C
CB
O
 ZN
O2
O
VAL B:151 B:173 0.0 0.0 E -137.6 132.2 NA NA NA
3ho5 2 Q15465 89.76 2e-110 X-RAY
 2009-06-23 VAL C:145 H:173 0.0 0.0 E -119.1 131.3 NA NA NA
3mxw 1 Q15465 89.76 2e-110 X-RAY
 2010-05-26 VAL A:145 A:173 0.0 0.0 E -132.3 133.2 0.0 0.0 0.0 ZN
SO4
HOH
 9.312
9.406
3.940
 C
C
CG2
 ZN
O2
O
6pjv 1 Q15465 89.76 2e-110 X-RAY
 2019-11-13 VAL A:145 A:173 0.0 0.0 E -136.1 132.9 0.0 0.0 0.0 DMS
DMS
ZN
MG
HOH
 7.449
8.157
8.935
8.935
3.095
 C
O
HA
HA
HG23
 H22
O
ZN
MG
O
6rmg 2 Q15465 89.76 8e-110 EM
 2019-10-09 VAL B:261 B:173 1.0 0.006 E -139.9 155.3 1.0 0.006 0.0 ZN
 8.722
 HA
 ZN
1vhh 1 Q62226 90.74 3e-108 X-RAY
 1996-01-29 VAL A:141 A:174 0.0 0.0 E -132.4 129.8 0.0 0.0 0.0 ZN
HOH
 9.290
2.674
 C
H
 ZN
H2
3d1m 1 Q62226 89.22 8e-108 X-RAY
 2008-09-23 VAL A:153 A:174 0.0 0.0 E -136.9 130.3 0.0 0.0 0.0 ZN
HOH
 9.542
4.062
 C
CG2
 ZN
O
VAL B:153 B:174 0.0 0.0 E -130.0 132.1 NA NA NA
7rpk 2 Q62226 89.7 3e-107 EM
 2021-10-27 VAL B:149 H:174 0.0 0.0 E -137.7 134.0 0.0 0.0 0.0 ZN
 9.625
 C
 ZN
4c4m 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 VAL A:137 A:174 0.0 0.0 E -131.1 130.3 0.0 0.0 0.0 ZN
HOH
 9.443
3.946
 C
CG2
 ZN
O
4c4n 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 VAL A:137 A:174 0.0 0.0 E -132.6 126.0 0.0 0.0 0.0 ZN
HOH
 9.505
3.706
 C
CG2
 ZN
O
VAL B:137 B:174 0.0 0.0 E -130.2 128.2 0.0 0.0 0.0 ZN
HOH
 9.484
5.718
 C
CG2
 ZN
O
3n1r 1 Q62226 91.67 6e-105 X-RAY
 2010-06-02 VAL A:139 A:174 0.0 0.0 E -119.1 135.8 0.0 0.0 0.0 ZN
HOH
 9.536
3.831
 C
CG2
 ZN
O
2wg4 1 Q62226 91.61 1e-104 X-RAY
 2009-06-30 VAL A:135 A:174 0.0 0.0 E -113.5 145.2 0.0 0.0 0.0 ZN
 9.487
 C
 ZN
2wfx 1 Q62226 92.11 3e-103 X-RAY
 2009-06-30 VAL A:135 A:174 0.0 0.0 E -109.1 133.5 0.0 0.0 0.0 ZN
 9.677
 C
 ZN

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14623-f1 1 Q14623 100.0 0.0 VAL A:178 A:178 0.0 0.0 E -133.9 132.8